Esterase inhibition in SH-SY5Y human neuroblastoma cells following exposure to organophosphorus compounds for 28 days

In Vitro and Molecular Toxicology: Journal of Basic and Applied Research

Volumn 14, Issue 2, 2001, Pages 129-135

  Barber, D S ^a   Ehrich, M ^a  

^a VIRGINIA MARYLAND REGIONAL COLLEGE OF VETERINARY MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINESTERASE; CHLORPYRIFOS; ESTERASE; ORGANOPHOSPHATE INSECTICIDE; PARAOXON; PARATHION; PHENYLSALIGENIN PHOSPHATE; TRICRESYL PHOSPHATE; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; INCUBATION TIME; NEUROBLASTOMA CELL; NEUROTOXICITY; TUMOR CELL CULTURE;

EID: 0034820619     PISSN: 10979336     EISSN: None     Source Type: Journal    
DOI: 10.1089/10979330152560522     Document Type: Article

References (22)

1. Comparison of two in vitro activation systems for protoxicant organophosphorous esterase inhibitors
2. Comparative effectiveness of organophosphorus protoxicant activating systems in neuroblastoma cells and brain homogenates
3. A microassay method for neurotoxic esterase determinations
4. Neural differentiation following culture of embryonal carcinoma cells in a serum-free defined medium
5. Subchronic delayed neurotoxicity evaluation of jet engine lubricants containing phosphorus additives
6. DDVP (dichlovos) detoxification by binding and interactions with DDT, dieldrin, and malaoxon
7. Organophosphate-induced delayed neuropathy
8. Neuropathy target esterase inhibition by organophosphorus esters in human neuroblastoma cells
9. Examination of culture conditions on esterase activities in human and mouse neuroblastoma cells
10. Acetylcholinesterase and neuropathy target esterase inhibitions in neuroblastoma cells to distinguish organophosphorus compounds causing acute and delayed neurotoxicity
11. Hydroxylation and cyclization reactions in the metabolism of tri-o-cresyl phosphate
12. Subchronic neurotoxicity of oil formulations containing either tricresyl phosphate or tri-orthocresyl phosphate
13. Neuropathy target esterase
14. The target for initiation of delayed neurotoxicity by organophosphorus esters: Biochemical studies and toxicological applications
15. Neurotoxicity of organophosphorus pesticides: Predictions can be based on in vitro studies with hen and human enzymes
16. Hepatic disposition of organophosphorus insecticides: A synthesis of in vitro, in situ and in vivo data
17. Chlorpyrifos: Assessment of potential for delayed neurotoxicity by repeated dosing in adult hens with monitoring of brain acetylcholinesterase, brain and lymphocyte neurotoxic esterase, and plasma butyrylcholinesterase activities
18. Screening acute, delayed and subchronic neurotoxicity studies in the hen: Measurements and evaluations of clinical signs following administration of TOCP
19. Species susceptibility to delayed toxic neuropathy in relation to in vivo inhibition of neurotoxic esterase by neurotoxic organophosphorus esters
20. Evaluation of a sensitive grading system for assessing acute and subchronic delayed neurotoxicity in hens
21. Time course for neurotoxic esterase activity in hens given multiple diisopropyl fluorophosphate injections