Opioids activate brain analgesic circuits through cytochrome P450/epoxygenase signaling

Nature Neuroscience

Volumn 13, Issue 3, 2010, Pages 284-286

  Conroy, Jennie L ^a   Fang, Cheng ^b   Gu, Jun ^b   Zeitlin, Scott O ^c   Yang, Weizhu ^b   Yang, Jun ^a   Vanalstine, Melissa A ^a   Nalwalk, Julia W ^a   Albrecht, Phillip J ^a,d   Mazurkiewicz, Joseph E ^a,d   Snyder Keller, Abigail ^b   Shan, Zhixing ^e   Zhang, Shao Zhong ^e   Wentland, Mark P ^e   Behr, Melissa ^b   Knapp, Brian I ^f   Bidlack, Jean M ^f   Zuiderveld, Obbe P ^g   Leurs, Rob ^g   Ding, Xinxin ^b   Hough, Lindsay B ^a   more..

^a ALBANY MEDICAL COLLEGE   (United States)

^b STATE UNIVERSITY OF NEW YORK   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

^d Integrated Tissue Dynamics   (United States)

^e Research Rensselaer Polytechnic Institute   (United States)

^f UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^g VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; CYTOCHROME P450; CYTOCHROME P450 EPOXYGENASE; MORPHINE; MU OPIATE RECEPTOR; UNCLASSIFIED DRUG;

ANALGESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; BRAIN NERVE CELL; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANALGESICS, OPIOID; ANIMALS; BRAIN; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FEMALE; MALE; MICE; MICE, TRANSGENIC; MORPHINE; NEURAL PATHWAYS; NEURONS; PAIN; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID, MU; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 77649183412     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/nn.2497     Document Type: Article

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