Augmented responses to morphine and cocaine in mice with a 12-lipoxygenase gene disruption

Psychopharmacology

Volumn 170, Issue 2, 2003, Pages 124-131

  Walters, Carrie L ^a   Wang, Bao Cheng ^a   Godfrey, Misty ^a   Sun, Duxin ^a   Funk, Colin D ^a   Blendy, Julie A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

12 lipoxygenase; Analgesia; C57B1 6 mice; Cocaine; Gene targeting; Morphine

Indexed keywords

ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONIC ACID; COCAINE; MORPHINE SULFATE;

ACUTE DRUG ADMINISTRATION; ANALGESIA; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DRUG WITHDRAWAL; FATTY ACID METABOLISM; FEMALE; GENE DISRUPTION; LEUKOCYTE; LOCOMOTION; MALE; MOUSE; MOUSE MUTANT; NONHUMAN; PRIORITY JOURNAL; THERMAL STIMULATION; WILD TYPE;

ANESTHETICS, LOCAL; ANIMALS; ARACHIDONATE 12-LIPOXYGENASE; AVOIDANCE LEARNING; BEHAVIOR, ANIMAL; COCAINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DRUG SYNERGISM; DRUG TOLERANCE; INHIBITION (PSYCHOLOGY); MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MORPHINE; MOTOR ACTIVITY; MUTATION; NARCOTICS; PAIN THRESHOLD; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SUBSTANCE WITHDRAWAL SYNDROME; SWIMMING;

EID: 0242576522     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-003-1526-7     Document Type: Article

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