Differential aiolos expression in human hematopoietic subpopulations

Leukemia Research

Volumn 34, Issue 3, 2010, Pages 289-293

  Billot, Katy ^a   Parizot, Christophe ^b   Arrouss, Issam ^a   Mazier, Dominique ^a   Debre, Patrice ^a   Rogner, Ute C ^c   Rebollo, Angelita ^a  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^c INSTITUT PASTEUR   (France)

Author keywords

Aiolos; B cells; Cord blood; NK cells; T cells

Indexed keywords

ABELSON KINASE; CD34 ANTIGEN; CD45RA ANTIGEN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AIOLOS; UNCLASSIFIED DRUG;

ARTICLE; B LYMPHOCYTE; CD34 SELECTION; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL SUBPOPULATION; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MEMORY T LYMPHOCYTE; MONOCYTE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; T LYMPHOCYTE;

B-LYMPHOCYTES; BLOTTING, WESTERN; CELL LINE; CELL SEPARATION; FETAL BLOOD; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELLS; HUMANS; IKAROS TRANSCRIPTION FACTOR; KILLER CELLS, NATURAL; LYMPHOCYTE SUBSETS; MONOCYTES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; T-LYMPHOCYTES;

EID: 77649179870     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2009.05.016     Document Type: Article

References (15)

1. Chiorazzi N., Hatzi K., Albesiano E. B-cell chronic lymphocytic leukemia, a clonal disease of B lymphocytes with receptors that vary in specificity for (auto)antigens. Ann N Y Acad Sci 2005, 1062:1-12.
2. Kuppers R. Mechanisms of B-cell lymphoma pathogenesis. Nat Rev Cancer 2005, 5:251-262.
3. Wang J.H., Avitahl N., Cariappa A., Friedrich C., Ikeda T., Renold A., et al. Aiolos regulates B cell activation and maturation to effector state. Immunity 1998, 9:543-553.
4. Kim J., Sif S., Jones B., Jackson A., Koipally J., Heller E., et al. Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes. Immunity 1999, 10:345-355.
5. Liippo J., Nera K.P., Veistinen E., Lahdesmaki A., Postila V., Kimby E., et al. Both normal and leukemic B lymphocytes express multiple isoforms of the human Aiolos gene. Eur J Immunol 2001, 31:3469-3474.
6. Morgan B., Sun L., Avitahl N., Andrikopoulos K., Ikeda T., Gonzales E., et al. Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation. EMBO J 1997, 16:2004-2013.
7. Caballero R., Setien F., Lopez-Serra L., Boix-Chornet M., Fraga M.F., Ropero S., et al. Combinatorial effects of splice variants modulate function of Aiolos. J Cell Sci 2007, 120:2619-2630.
8. Hosokawa Y., Maeda Y., Takahashi E., Suzuki M., Seto M. Human aiolos, an ikaros-related zinc finger DNA binding protein: cDNA cloning, tissue expression pattern, and chromosomal mapping. Genomics 1999, 61:326-329.
9. Duhamel M., Arrouss I., Merle-Beral H., Rebollo A. The Aiolos transcription factor is up-regulated in chronic lymphocytic leukemia. Blood 2008, 111:3225-3228.
10. Duhamel M., Navarro P., Cario-Andre M., Billot K., Arrouss I., Rebollo A. Differential epigenetic regulation of Aiolos expression in human tumoral cell lines and primary cells. FEBS Lett 2008, 582:457-467.
11. Nakase K., Ishimaru F., Fujii K., Tabayashi T., Kozuka T., Sezaki N., et al. Overexpression of novel short isoforms of Helios in a patient with T-cell acute lymphoblastic leukaemia. Exp Hematol 2002, 30:313-317.
12. Antica M., Dubravcic K., Weber I., Raic L., Labar B., Batinic D. A search for a mutation of the Aiolos phosphorylation domain in lymphocytes from patients with leukemia. Haematologica 2007, 92:260-261.
13. Nuckel H., Frey U.H., Sellmann L., Collins C.H., Duhrsen U., Siffert W., et al. (Aiolos) transcription factor is highly upregulated and inversely correlated with clinical progression in chronic lymphocytic leukaemia. Br J Haematol 2009, 144:268-270.
14. Narvi E., Nera K.P., Terho P., Mustonen L., Granberg J., Lassila O. Aiolos controls gene conversion and cell death in DT40 B cells. Scand J Immunol 2007, 65:503-513.
15. Cariappa A., Tang M., Parng C., Nebelitskiy E., Carroll M., Georgopoulos K., et al. The follicular versus marginal zone B lymphocyte cell fate decision is regulated by Aiolos, Btk, and CD21. Immunity 2001, 14:603-615.