-
1
-
-
0031883280
-
A dominant-negative inhibitor of CREB reveals that it is a general mediator of stimulus-dependent transcription of c-fos
-
Ahn S, Olive M, Aggarwal S, Krylov D, Ginty DD, Vinson C. A dominant-negative inhibitor of CREB reveals that it is a general mediator of stimulus-dependent transcription of c-fos. Mol Cell Biol 18: 967-977, 1998.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 967-977
-
-
Ahn, S.1
Olive, M.2
Aggarwal, S.3
Krylov, D.4
Ginty, D.D.5
Vinson, C.6
-
2
-
-
68049125868
-
ES cell cycle progression and differentiation require the action of the histone methyltransferase Dot1L
-
Barry ER, Krueger W, Jakuba CM, Veilleux E, Ambrosi DJ, Nelson CE, Rasmussen TP. ES cell cycle progression and differentiation require the action of the histone methyltransferase Dot1L. Stem Cells 27: 1538-1547, 2009.
-
(2009)
Stem Cells
, vol.27
, pp. 1538-1547
-
-
Barry, E.R.1
Krueger, W.2
Jakuba, C.M.3
Veilleux, E.4
Ambrosi, D.J.5
Nelson, C.E.6
Rasmussen, T.P.7
-
3
-
-
34447525522
-
Tissuespecific mechanisms for CCN2/CTGF persistence in fibrotic gingiva: Interactions between cAMP and MAPK signaling pathways, and prostaglandin E2-EP3 receptor mediated activation of the c-JUN N-terminal kinase
-
Black SA Jr, Palamakumbura AH, Stan M, Trackman PC. Tissuespecific mechanisms for CCN2/CTGF persistence in fibrotic gingiva: interactions between cAMP and MAPK signaling pathways, and prostaglandin E2-EP3 receptor mediated activation of the c-JUN N-terminal kinase. J Biol Chem 282: 15416-15429, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 15416-15429
-
-
Black Jr, S.A.1
Palamakumbura, A.H.2
Stan, M.3
Trackman, P.C.4
-
4
-
-
0034970113
-
In vitro evidence for differential involvement of CTGF, TGFbeta, and PDGF-BB in mesangial response to injury
-
Blom IE, van Dijk AJ, Wieten L, Duran K, Ito Y, Kleij L, deNichilo M, Rabelink TJ, Weening JJ, Aten J, Goldschmeding R. In vitro evidence for differential involvement of CTGF, TGFbeta, and PDGF-BB in mesangial response to injury. Nephrol Dial Transplant 16: 1139-1148, 2001.
-
(2001)
Nephrol Dial Transplant
, vol.16
, pp. 1139-1148
-
-
Blom, I.E.1
van Dijk, A.J.2
Wieten, L.3
Duran, K.4
Ito, Y.5
Kleij, L.6
deNichilo, M.7
Rabelink, T.J.8
Weening, J.J.9
Aten, J.10
Goldschmeding, R.11
-
5
-
-
34250733867
-
The role of tubular epithelialmesenchymal transition in progressive kidney disease
-
Burns WC, Kantharidis P, Thomas MC. The role of tubular epithelialmesenchymal transition in progressive kidney disease. Cells Tissues Organs 185: 222-231, 2007.
-
(2007)
Cells Tissues Organs
, vol.185
, pp. 222-231
-
-
Burns, W.C.1
Kantharidis, P.2
Thomas, M.C.3
-
7
-
-
0027433708
-
Phosphorylated CREB binds specifically to the nuclear protein CBP
-
Chrivia JC, Kwok RP, Lamb N, Hagiwara M, Montminy MR, Goodman RH. Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature 365: 855-859, 1993.
-
(1993)
Nature
, vol.365
, pp. 855-859
-
-
Chrivia, J.C.1
Kwok, R.P.2
Lamb, N.3
Hagiwara, M.4
Montminy, M.R.5
Goodman, R.H.6
-
8
-
-
24344482544
-
CREB: The unindicted cancer co-conspirator
-
Conkright MD, Montminy M. CREB: the unindicted cancer co-conspirator. Trends Cell Biol 15: 457-459, 2005.
-
(2005)
Trends Cell Biol
, vol.15
, pp. 457-459
-
-
Conkright, M.D.1
Montminy, M.2
-
9
-
-
0035853761
-
Consensus and variant cAMP-regulated enhancers have distinct CREB-binding properties
-
Craig JC, Schumacher MA, Mansoor SE, Farrens DL, Brennan RG, Goodman RH. Consensus and variant cAMP-regulated enhancers have distinct CREB-binding properties. J Biol Chem 276: 11719-11728, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 11719-11728
-
-
Craig, J.C.1
Schumacher, M.A.2
Mansoor, S.E.3
Farrens, D.L.4
Brennan, R.G.5
Goodman, R.H.6
-
10
-
-
0032873465
-
Connective tissue growth factor mediates transforming growth factor beta-induced collagen synthesis: Downregulation by cAMP
-
Duncan MR, Frazier KS, Abramson S, Williams S, Klapper H, Huang X, Grotendorst GR. Connective tissue growth factor mediates transforming growth factor beta-induced collagen synthesis: downregulation by cAMP. FASEB J 13: 1774-1786, 1999.
-
(1999)
FASEB J
, vol.13
, pp. 1774-1786
-
-
Duncan, M.R.1
Frazier, K.S.2
Abramson, S.3
Williams, S.4
Klapper, H.5
Huang, X.6
Grotendorst, G.R.7
-
11
-
-
44849112242
-
Nonprocessive methylation by Dot1 leads to functional redundancy of histone H3K79 methylation states
-
Frederiks F, Tzouros M, Oudgenoeg G, van Welsem T, Fornerod M, Krijgsveld J, van Leeuwen F. Nonprocessive methylation by Dot1 leads to functional redundancy of histone H3K79 methylation states. Nat Struct Mol Biol 15: 550-557, 2008.
-
(2008)
Nat Struct Mol Biol
, vol.15
, pp. 550-557
-
-
Frederiks, F.1
Tzouros, M.2
Oudgenoeg, G.3
van Welsem, T.4
Fornerod, M.5
Krijgsveld, J.6
van Leeuwen, F.7
-
12
-
-
36749057921
-
Aldosterone induces CTGF in mesangial cells by activation of the glucocorticoid receptor
-
Gauer S, Segitz V, Goppelt-Struebe M. Aldosterone induces CTGF in mesangial cells by activation of the glucocorticoid receptor. Nephrol Dial Transplant 22: 3154-3159, 2007.
-
(2007)
Nephrol Dial Transplant
, vol.22
, pp. 3154-3159
-
-
Gauer, S.1
Segitz, V.2
Goppelt-Struebe, M.3
-
13
-
-
0036783550
-
TGF-β and CTGF have overlapping and distinct fibrogenic effects on human renal cells
-
Gore-Hyer E, Shegogue D, Markiewicz M, Lo S, Hazen-Martin D, Greene EL, Grotendorst G, Trojanowska M. TGF-β and CTGF have overlapping and distinct fibrogenic effects on human renal cells. Am J Physiol Renal Physiol 283: F707-F716, 2002.
-
(2002)
Am J Physiol Renal Physiol
, vol.283
-
-
Gore-Hyer, E.1
Shegogue, D.2
Markiewicz, M.3
Lo, S.4
Hazen-Martin, D.5
Greene, E.L.6
Grotendorst, G.7
Trojanowska, M.8
-
14
-
-
0034870254
-
Expression of connective tissue growth factor in human renal fibroblasts: Regulatory roles of RhoA and cAMP
-
Heusinger-Ribeiro J, Eberlein M, Wahab NA, Goppelt-Struebe M. Expression of connective tissue growth factor in human renal fibroblasts: regulatory roles of RhoA and cAMP. J Am Soc Nephrol 12: 1853-1861, 2001.
-
(2001)
J Am Soc Nephrol
, vol.12
, pp. 1853-1861
-
-
Heusinger-Ribeiro, J.1
Eberlein, M.2
Wahab, N.A.3
Goppelt-Struebe, M.4
-
16
-
-
52949107241
-
The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure
-
Jones B, Su H, Bhat A, Lei H, Bajko J, Hevi S, Baltus GA, Kadam S, Zhai H, Valdez R, Gonzalo S, Zhang Y, Li E, Chen T. The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure. PLoS Genet 4: e100-0190, 2008.
-
(2008)
PLoS Genet
, vol.4
-
-
Jones, B.1
Su, H.2
Bhat, A.3
Lei, H.4
Bajko, J.5
Hevi, S.6
Baltus, G.A.7
Kadam, S.8
Zhai, H.9
Valdez, R.10
Gonzalo, S.11
Zhang, Y.12
Li, E.13
Chen, T.14
-
17
-
-
0037163016
-
Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase
-
Lacoste N, Utley RT, Hunter JM, Poirier GG, Cote J. Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase. J Biol Chem 277: 30421-30424, 2002.]
-
(2002)
J Biol Chem
, vol.277
, pp. 30421-30424
-
-
Lacoste, N.1
Utley, R.T.2
Hunter, J.M.3
Poirier, G.G.4
Cote, J.5
-
18
-
-
31744440775
-
Pentoxifylline attenuates tubulointerstitial fibrosis by blocking Smad3/4-activated transcription and profibrogenic effects of connective tissue growth factor
-
Lin SL, Chen RH, Chen YM, Chiang WC, Lai CF, Wu KD, Tsai TJ. Pentoxifylline attenuates tubulointerstitial fibrosis by blocking Smad3/4-activated transcription and profibrogenic effects of connective tissue growth factor. J Am Soc Nephrol 16: 2702-2713, 2005.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 2702-2713
-
-
Lin, S.L.1
Chen, R.H.2
Chen, Y.M.3
Chiang, W.C.4
Lai, C.F.5
Wu, K.D.6
Tsai, T.J.7
-
19
-
-
0037362456
-
Roles of connective tissue growth factor and prostanoids in early streptozotocin-induced diabetic rat kidney: The effect of aspirin treatment
-
Makino H, Mukoyama M, Sugawara A, Mori K, Suganami T, Yahata K, Fujinaga Y, Yokoi H, Tanaka I, Nakao K. Roles of connective tissue growth factor and prostanoids in early streptozotocin-induced diabetic rat kidney: the effect of aspirin treatment. Clin Exp Nephrol 7: 33-40, 2003.
-
(2003)
Clin Exp Nephrol
, vol.7
, pp. 33-40
-
-
Makino, H.1
Mukoyama, M.2
Sugawara, A.3
Mori, K.4
Suganami, T.5
Yahata, K.6
Fujinaga, Y.7
Yokoi, H.8
Tanaka, I.9
Nakao, K.10
-
21
-
-
0000690898
-
Identification of a cyclic-AMP-responsive element within the rat somatostatin gene
-
Montminy MR, Sevarino KA, Wagner JA, Mandel G, Goodman RH. Identification of a cyclic-AMP-responsive element within the rat somatostatin gene. Proc Natl Acad Sci USA 83: 6682-6686, 1986.
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 6682-6686
-
-
Montminy, M.R.1
Sevarino, K.A.2
Wagner, J.A.3
Mandel, G.4
Goodman, R.H.5
-
22
-
-
0037452770
-
Lysine-79 of histone H3 is hypomethylated at silenced loci in yeast and mammalian cells: A potential mechanism for position effect variegation
-
Ng HH, Ciccone DN, Morshead KB, Oettinger MA, Struhl K. Lysine-79 of histone H3 is hypomethylated at silenced loci in yeast and mammalian cells: a potential mechanism for position effect variegation. Proc Natl Acad Sci USA 100: 1820-1825, 2003.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 1820-1825
-
-
Ng, H.H.1
Ciccone, D.N.2
Morshead, K.B.3
Oettinger, M.A.4
Struhl, K.5
-
23
-
-
48649102468
-
Plasma connective tissue growth factor is an independent predictor of end-stage renal disease and mortality in type 1 diabetic nephropathy
-
Nguyen TQ, Tarnow L, Jorsal A, Oliver N, Roestenberg P, Ito Y, Parving HH, Rossing P, van Nieuwenhoven FA, Goldschmeding R. Plasma connective tissue growth factor is an independent predictor of end-stage renal disease and mortality in type 1 diabetic nephropathy. Diabetes Care 31: 1177-1182, 2008.
-
(2008)
Diabetes Care
, vol.31
, pp. 1177-1182
-
-
Nguyen, T.Q.1
Tarnow, L.2
Jorsal, A.3
Oliver, N.4
Roestenberg, P.5
Ito, Y.6
Parving, H.H.7
Rossing, P.8
van Nieuwenhoven, F.A.9
Goldschmeding, R.10
-
24
-
-
72149098573
-
+ channel
-
+ channel. J Biol Chem 284: 35659-35669, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 35659-35669
-
-
Reisenauer, M.R.1
Anderson, M.2
Huang, L.3
Zhang, Z.4
Zhou, Q.5
Kone, B.C.6
Morris, A.P.7
Lesage, G.D.8
Dryer, S.E.9
Zhang, W.10
-
25
-
-
0033579301
-
Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons
-
Riccio A, Ahn S, Davenport CM, Blendy JA, Ginty DD. Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons. Science 286: 2358-2361, 1999.
-
(1999)
Science
, vol.286
, pp. 2358-2361
-
-
Riccio, A.1
Ahn, S.2
Davenport, C.M.3
Blendy, J.A.4
Ginty, D.D.5
-
26
-
-
0033387824
-
Regulation of connective tissue growth factor expression by prostaglandin E2
-
Ricupero DA, Rishikof DC, Kuang PP, Poliks CF, Goldstein RH. Regulation of connective tissue growth factor expression by prostaglandin E2. Am J Physiol Lung Cell Mol Physiol 277: L1165-L1171, 1999.
-
(1999)
Am J Physiol Lung Cell Mol Physiol
, vol.277
-
-
Ricupero, D.A.1
Rishikof, D.C.2
Kuang, P.P.3
Poliks, C.F.4
Goldstein, R.H.5
-
27
-
-
0033957976
-
Regulation of connective tissue growth factor activity in cultured rat mesangial cells and its expression in experimental diabetic glomerulosclerosis
-
Riser BL, Denichilo M, Cortes P, Baker C, Grondin JM, Yee J, Narins RG. Regulation of connective tissue growth factor activity in cultured rat mesangial cells and its expression in experimental diabetic glomerulosclerosis. J Am Soc Nephrol 11: 25-38, 2000.
-
(2000)
J Am Soc Nephrol
, vol.11
, pp. 25-38
-
-
Riser, B.L.1
Denichilo, M.2
Cortes, P.3
Baker, C.4
Grondin, J.M.5
Yee, J.6
Narins, R.G.7
-
28
-
-
34547890019
-
Functions of site-specific histone acetylation and deacetylation
-
Shahbazian MD, Grunstein M. Functions of site-specific histone acetylation and deacetylation. Annu Rev Biochem 76: 75-100, 2007.
-
(2007)
Annu Rev Biochem
, vol.76
, pp. 75-100
-
-
Shahbazian, M.D.1
Grunstein, M.2
-
29
-
-
40749107501
-
Regulation and function of connective tissue growth factor/CCN2 in tissue repair, scarring and fibrosis
-
Shi-Wen X, Leask A, Abraham D. Regulation and function of connective tissue growth factor/CCN2 in tissue repair, scarring and fibrosis. Cytokine Growth Factor Rev 19: 133-144, 2008.
-
(2008)
Cytokine Growth Factor Rev
, vol.19
, pp. 133-144
-
-
Shi-Wen, X.1
Leask, A.2
Abraham, D.3
-
30
-
-
0034610814
-
The language of covalent histone modifications
-
Strahl BD, Allis CD. The language of covalent histone modifications. Nature 403: 41-45, 2000.
-
(2000)
Nature
, vol.403
, pp. 41-45
-
-
Strahl, B.D.1
Allis, C.D.2
-
31
-
-
39049092072
-
Aldosterone-stimulated SGK1 activity mediates profi-brotic signaling in the mesangium
-
Terada Y, Kuwana H, Kobayashi T, Okado T, Suzuki N, Yoshimoto T, Hirata Y, Sasaki S. Aldosterone-stimulated SGK1 activity mediates profi-brotic signaling in the mesangium. J Am Soc Nephrol 19: 298-309, 2008.
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 298-309
-
-
Terada, Y.1
Kuwana, H.2
Kobayashi, T.3
Okado, T.4
Suzuki, N.5
Yoshimoto, T.6
Hirata, Y.7
Sasaki, S.8
-
32
-
-
5444223019
-
Site-specific analysis of histone methylation and acetylation
-
Umlauf D, Goto Y, Feil R. Site-specific analysis of histone methylation and acetylation. Methods Mol Biol 287: 99-120, 2004.
-
(2004)
Methods Mol Biol
, vol.287
, pp. 99-120
-
-
Umlauf, D.1
Goto, Y.2
Feil, R.3
-
33
-
-
0037077178
-
Dot1p modulates silencing in yeast by methylation of the nucleosome core
-
van Leeuwen F, Gafken PR, Gottschling DE. Dot1p modulates silencing in yeast by methylation of the nucleosome core. Cell 109: 745-756, 2002.
-
(2002)
Cell
, vol.109
, pp. 745-756
-
-
van Leeuwen, F.1
Gafken, P.R.2
Gottschling, D.E.3
-
34
-
-
0030733076
-
The vascular smooth muscle type I angiotensin II receptor mRNA is destabilized by cyclic AMP-elevating agents
-
Wang X, Nickenig G, Murphy TJ. The vascular smooth muscle type I angiotensin II receptor mRNA is destabilized by cyclic AMP-elevating agents. Mol Pharmacol 52: 781-787, 1997.
-
(1997)
Mol Pharmacol
, vol.52
, pp. 781-787
-
-
Wang, X.1
Nickenig, G.2
Murphy, T.J.3
-
35
-
-
33845262861
-
Renal injury due to renin-angiotensin-aldosterone system activation of the transforming growth factor-beta pathway
-
Wolf G. Renal injury due to renin-angiotensin-aldosterone system activation of the transforming growth factor-beta pathway. Kidney Int 70: 1914-1919, 2006.
-
(2006)
Kidney Int
, vol.70
, pp. 1914-1919
-
-
Wolf, G.1
-
36
-
-
25444466892
-
Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9
-
Wysocki R, Javaheri A, Allard S, Sha F, Cote J, Kron SJ. Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9. Mol Cell Biol 25: 8430-8443, 2005.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 8430-8443
-
-
Wysocki, R.1
Javaheri, A.2
Allard, S.3
Sha, F.4
Cote, J.5
Kron, S.J.6
-
38
-
-
0028345893
-
A constitutively active form of CREB can activate expression of the rat prolactin promoter in nonpituitary cells
-
Yan G, Chen X, Bancroft C. A constitutively active form of CREB can activate expression of the rat prolactin promoter in nonpituitary cells. Mol Cell Endocrinol 101: R25-R30, 1994.
-
(1994)
Mol Cell Endocrinol
, vol.101
-
-
Yan, G.1
Chen, X.2
Bancroft, C.3
-
39
-
-
70349659185
-
Angiotensin II induces connective tissue growth factor and collagen I expression via transforming growth factor-beta-dependent and -independent Smad pathways: The role of Smad3
-
Yang F, Chung AC, Huang XR, Lan HY. Angiotensin II induces connective tissue growth factor and collagen I expression via transforming growth factor-beta-dependent and -independent Smad pathways: the role of Smad3. Hypertension 54: 877-884, 2009.
-
(2009)
Hypertension
, vol.54
, pp. 877-884
-
-
Yang, F.1
Chung, A.C.2
Huang, X.R.3
Lan, H.Y.4
-
40
-
-
58349113159
-
Epigenetics and the control of epithelial sodium channel expression in collecting duct
-
Zhang D, Yu ZY, Cruz P, Kong Q, Li S, Kone BC. Epigenetics and the control of epithelial sodium channel expression in collecting duct. Kidney Int 75: 260-267, 2009.
-
(2009)
Kidney Int
, vol.75
, pp. 260-267
-
-
Zhang, D.1
Yu, Z.Y.2
Cruz, P.3
Kong, Q.4
Li, S.5
Kone, B.C.6
-
41
-
-
68949129008
-
Sirtuin 1 functionally and physically interacts with disruptor of telomeric silencing-1 to regulate alpha-ENaC transcription in collecting duct
-
Zhang D, Li S, Cruz P, Kone BC. Sirtuin 1 functionally and physically interacts with disruptor of telomeric silencing-1 to regulate alpha-ENaC transcription in collecting duct. J Biol Chem 284: 20917-20926, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 20917-20926
-
-
Zhang, D.1
Li, S.2
Cruz, P.3
Kone, B.C.4
-
42
-
-
1242269799
-
Structure and regulation of the mDot1 gene, a mouse histone H3 methyltransferase
-
Zhang W, Hayashizaki Y, Kone BC. Structure and regulation of the mDot1 gene, a mouse histone H3 methyltransferase. Biochem J 377: 641-651, 2004.
-
(2004)
Biochem J
, vol.377
, pp. 641-651
-
-
Zhang, W.1
Hayashizaki, Y.2
Kone, B.C.3
-
43
-
-
33645459867
-
Aldosterone-sensitive repression of ENaC transcription by a histone H3 lysine-79 methyltransferase
-
Zhang W, Xia X, Jalal DI, Kuncewicz T, Xu W, Lesage GD, Kone BC. Aldosterone-sensitive repression of ENaC transcription by a histone H3 lysine-79 methyltransferase. Am J Physiol Cell Physiol 290: C936-C946, 2006.
-
(2006)
Am J Physiol Cell Physiol
, vol.290
-
-
Zhang, W.1
Xia, X.2
Jalal, D.I.3
Kuncewicz, T.4
Xu, W.5
Lesage, G.D.6
Kone, B.C.7
-
44
-
-
33745873838
-
Dot1a-AF9 complex mediates histone H3 Lys-79 hypermethylation and repression of ENaCalpha in an aldosterone-sensitive manner
-
Zhang W, Xia X, Reisenauer MR, Hemenway CS, Kone BC. Dot1a-AF9 complex mediates histone H3 Lys-79 hypermethylation and repression of ENaCalpha in an aldosterone-sensitive manner. J Biol Chem 281: 18059-18068, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 18059-18068
-
-
Zhang, W.1
Xia, X.2
Reisenauer, M.R.3
Hemenway, C.S.4
Kone, B.C.5
-
45
-
-
33847412788
-
+ channel alpha
-
+ channel alpha. J Clin Invest 117: 773-783, 2007.
-
(2007)
J Clin Invest
, vol.117
, pp. 773-783
-
-
Zhang, W.1
Xia, X.2
Reisenauer, M.R.3
Rieg, T.4
Lang, F.5
Kuhl, D.6
Vallon, V.7
Kone, B.C.8
|