메뉴 건너뛰기




Volumn 100, Issue 1, 2010, Pages 55-64

Identification of potential targets in biological signalling systems through network perturbation analysis

Author keywords

Adenosine; Biological signalling networks; Boolean networks; Calcium; Caspase 3; Network vulnerability; Perturbation analysis

Indexed keywords

ADENOSINE; CALCIUM;

EID: 77549087194     PISSN: 03032647     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biosystems.2010.01.002     Document Type: Article
Times cited : (12)

References (31)
  • 1
    • 58149261709 scopus 로고    scopus 로고
    • Fault diagnosis engineering of digital circuits can identify vulnerable molecules in complex cellular pathways
    • ra10, doi:10.1126/scisignal.2000008
    • Abdi A., Tahoori M.B., and Emamian E.S. Fault diagnosis engineering of digital circuits can identify vulnerable molecules in complex cellular pathways. Sci. Signal. 1 (2008) ra10, doi:10.1126/scisignal.2000008
    • (2008) Sci. Signal. , vol.1
    • Abdi, A.1    Tahoori, M.B.2    Emamian, E.S.3
  • 2
    • 0034721164 scopus 로고    scopus 로고
    • Error and attack tolerance of complex networks
    • doi:10.1038/35019019
    • Albert R., Jeong H., and Barabasi A.L. Error and attack tolerance of complex networks. Nature 406 (2000) 378-382 doi:10.1038/35019019
    • (2000) Nature , vol.406 , pp. 378-382
    • Albert, R.1    Jeong, H.2    Barabasi, A.L.3
  • 5
    • 18844380444 scopus 로고    scopus 로고
    • Robustness and fragility of Boolean models for genetic regulatory networks
    • Chaves M., Albert R., and Sontag E.D. Robustness and fragility of Boolean models for genetic regulatory networks. J. Theor. Biol. 235 (2005) 431-449
    • (2005) J. Theor. Biol. , vol.235 , pp. 431-449
    • Chaves, M.1    Albert, R.2    Sontag, E.D.3
  • 6
    • 35348891430 scopus 로고    scopus 로고
    • Network-based classification of breast cancer metastasis
    • doi:10.1038/msb4100180
    • Chuang H.Y., Lee E., Liu Y.T., Lee D., and Ideker T. Network-based classification of breast cancer metastasis. Mol. Syst. Biol. 3 (2007) 140 doi:10.1038/msb4100180
    • (2007) Mol. Syst. Biol. , vol.3 , pp. 140
    • Chuang, H.Y.1    Lee, E.2    Liu, Y.T.3    Lee, D.4    Ideker, T.5
  • 8
    • 33748749963 scopus 로고    scopus 로고
    • Adenosine inhibits matrix metalloproteinase-9 secretion by neutrophils: implication of A2a receptor and cAMP/PKA/Ca2+ pathway
    • 10.1161/01.RES.0000241428.82502.d4
    • Ernens I., Rouy D., Velot E., Devaux Y., and Wagner D.R. Adenosine inhibits matrix metalloproteinase-9 secretion by neutrophils: implication of A2a receptor and cAMP/PKA/Ca2+ pathway. Circ Res. 99 (2006) 590-597 10.1161/01.RES.0000241428.82502.d4
    • (2006) Circ Res. , vol.99 , pp. 590-597
    • Ernens, I.1    Rouy, D.2    Velot, E.3    Devaux, Y.4    Wagner, D.R.5
  • 9
    • 71749121782 scopus 로고    scopus 로고
    • A multi-objective differential evolutionary approach toward more stable gene regulatory networks
    • 10.1016/j.biosystems.2009.09.002
    • Esmaeili A., and Jacob C. A multi-objective differential evolutionary approach toward more stable gene regulatory networks. BioSystems 98 (2009) 127-136 10.1016/j.biosystems.2009.09.002
    • (2009) BioSystems , vol.98 , pp. 127-136
    • Esmaeili, A.1    Jacob, C.2
  • 10
    • 34250770500 scopus 로고    scopus 로고
    • Adenosine, an endogenous distress signal, modulates tissue damage and repair
    • 10.1038/sj.cdd.4402132
    • Fredholm B.B. Adenosine, an endogenous distress signal, modulates tissue damage and repair. Cell Death Differ. 14 (2007) 1315-1323 10.1038/sj.cdd.4402132
    • (2007) Cell Death Differ. , vol.14 , pp. 1315-1323
    • Fredholm, B.B.1
  • 11
    • 34848826034 scopus 로고    scopus 로고
    • Influence of degree correlations on network structure and stability in protein-protein interaction networks
    • 10.1186/1471-2105-8-297
    • Friedel C.C., and Zimmer R. Influence of degree correlations on network structure and stability in protein-protein interaction networks. BMC Bioinform. 8 (2007) 297 10.1186/1471-2105-8-297
    • (2007) BMC Bioinform. , vol.8 , pp. 297
    • Friedel, C.C.1    Zimmer, R.2
  • 13
    • 0142170014 scopus 로고    scopus 로고
    • Acute adenosinergic cardioprotection in ischemic-reperfused hearts
    • 10.1152/ajpheart.00407.2003
    • Headrick J.P., Hack B., and Ashton K.J. Acute adenosinergic cardioprotection in ischemic-reperfused hearts. Am. J. Physiol. Heart Circ. Physiol. 285 (2003) H1797-H1818 10.1152/ajpheart.00407.2003
    • (2003) Am. J. Physiol. Heart Circ. Physiol. , vol.285
    • Headrick, J.P.1    Hack, B.2    Ashton, K.J.3
  • 14
    • 41149165188 scopus 로고    scopus 로고
    • Emergent decision-making in biological signal transduction networks
    • 10.1073/pnas.0705088105
    • Helikar T., Konvalina J., Heidel J., and Rogers J.A. Emergent decision-making in biological signal transduction networks. Proc. Natl. Acad. Sci. U.S.A. 105 (2008) 1913-1918 10.1073/pnas.0705088105
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 1913-1918
    • Helikar, T.1    Konvalina, J.2    Heidel, J.3    Rogers, J.A.4
  • 15
    • 33644770260 scopus 로고    scopus 로고
    • Adenosine receptors as therapeutic targets
    • doi:10.1038/nrd1983
    • Jacobson K.A., and Gao Z.G. Adenosine receptors as therapeutic targets. Nat. Rev. Drug Discov. 5 (2006) 247-264 doi:10.1038/nrd1983
    • (2006) Nat. Rev. Drug Discov. , vol.5 , pp. 247-264
    • Jacobson, K.A.1    Gao, Z.G.2
  • 16
    • 0842320458 scopus 로고    scopus 로고
    • A high-throughput quantitative multiplex kinase assay for monitoring information flow in signaling networks: application to sepsis-apoptosis
    • 10.1074/mcp.M300045-MCP200
    • Janes K.A., Albeck J.G., Peng L.X., Sorger P.K., Lauffenburger D.A., and Yaffe M.B. A high-throughput quantitative multiplex kinase assay for monitoring information flow in signaling networks: application to sepsis-apoptosis. Mol. Cell. Proteomics 2 (2003) 463-473 10.1074/mcp.M300045-MCP200
    • (2003) Mol. Cell. Proteomics , vol.2 , pp. 463-473
    • Janes, K.A.1    Albeck, J.G.2    Peng, L.X.3    Sorger, P.K.4    Lauffenburger, D.A.5    Yaffe, M.B.6
  • 17
    • 33646036758 scopus 로고    scopus 로고
    • The response of human epithelial cells to TNF involves an inducible autocrine cascade
    • 10.1016/j.cell.2006.01.041
    • Janes K.A., Gaudet S., Albeck J.G., Nielsen U.B., Lauffenburger D.A., and Sorger P.K. The response of human epithelial cells to TNF involves an inducible autocrine cascade. Cell 124 (2006) 1225-1239 10.1016/j.cell.2006.01.041
    • (2006) Cell , vol.124 , pp. 1225-1239
    • Janes, K.A.1    Gaudet, S.2    Albeck, J.G.3    Nielsen, U.B.4    Lauffenburger, D.A.5    Sorger, P.K.6
  • 18
    • 71749110375 scopus 로고    scopus 로고
    • Guest editorial: special section on evolving gene regulatory networks
    • 10.1016/j.biosystems.2009.10.001
    • Jin Y., and Hallinan J. Guest editorial: special section on evolving gene regulatory networks. BioSystems 98 (2009) vi-vii 10.1016/j.biosystems.2009.10.001
    • (2009) BioSystems , vol.98
    • Jin, Y.1    Hallinan, J.2
  • 19
    • 0014489272 scopus 로고
    • Metabolic stability and epigenesis in randomly constructed genetic nets
    • Kauffman S.A. Metabolic stability and epigenesis in randomly constructed genetic nets. J. Theor. Biol. 22 (1969) 437-467
    • (1969) J. Theor. Biol. , vol.22 , pp. 437-467
    • Kauffman, S.A.1
  • 20
  • 21
    • 33847377573 scopus 로고    scopus 로고
    • A robustness-based approach to systems-oriented drug design
    • doi:10.1038/nrd21959
    • Kitano H. A robustness-based approach to systems-oriented drug design. Nat. Rev. Drug Discov. 6 (2007) 202-210 doi:10.1038/nrd21959
    • (2007) Nat. Rev. Drug Discov. , vol.6 , pp. 202-210
    • Kitano, H.1
  • 22
    • 33646337667 scopus 로고    scopus 로고
    • A methodology for the structural and functional analysis of signaling and regulatory networks
    • Klamt S., Saez-Rodriguez J., Lindquist J.A., Simeoni L., and Gilles E.D. A methodology for the structural and functional analysis of signaling and regulatory networks. BMC Bioinform. 7 (2006) 56
    • (2006) BMC Bioinform. , vol.7 , pp. 56
    • Klamt, S.1    Saez-Rodriguez, J.2    Lindquist, J.A.3    Simeoni, L.4    Gilles, E.D.5
  • 23
    • 39149143293 scopus 로고    scopus 로고
    • A systems biology approach to prediction of oncogenes and molecular perturbation targets in B-cell lymphomas
    • doi:10.1038/msb.2008.2
    • Mani K.M., Lefebvre C., Wang K., Lim W.K., Basso K., Dalla-Favera R., and Califano A. A systems biology approach to prediction of oncogenes and molecular perturbation targets in B-cell lymphomas. Mol. Syst. Biol. 4 (2008) 16 doi:10.1038/msb.2008.2
    • (2008) Mol. Syst. Biol. , vol.4 , pp. 16
    • Mani, K.M.1    Lefebvre, C.2    Wang, K.3    Lim, W.K.4    Basso, K.5    Dalla-Favera, R.6    Califano, A.7
  • 26
    • 0038771191 scopus 로고    scopus 로고
    • Signalling from adenosine receptors to mitogen-activated protein kinases
    • doi:10.1016/S0898-6568(03)00058-5
    • Schulte G., and Fredholm B.B. Signalling from adenosine receptors to mitogen-activated protein kinases. Cell Signal. 15 (2003) 813-827 doi:10.1016/S0898-6568(03)00058-5
    • (2003) Cell Signal. , vol.15 , pp. 813-827
    • Schulte, G.1    Fredholm, B.B.2
  • 27
    • 2542432162 scopus 로고    scopus 로고
    • Physiological control of immune response and inflammatory tissue damage by hypoxia-inducible factors and adenosine A2A receptors
    • doi:10.1146/annurev.immunol.22.012703.104731
    • Sitkovsky M.V., Lukashev D., Apasov S., Kojima H., Koshiba M., Caldwell C., Ohta A., and Thiel M. Physiological control of immune response and inflammatory tissue damage by hypoxia-inducible factors and adenosine A2A receptors. Annu. Rev. Immunol. 22 (2004) 657-682 doi:10.1146/annurev.immunol.22.012703.104731
    • (2004) Annu. Rev. Immunol. , vol.22 , pp. 657-682
    • Sitkovsky, M.V.1    Lukashev, D.2    Apasov, S.3    Kojima, H.4    Koshiba, M.5    Caldwell, C.6    Ohta, A.7    Thiel, M.8
  • 28
    • 4544346660 scopus 로고    scopus 로고
    • Robustness of cellular functions
    • 10.1016/j.cell.2004.09.008
    • Stelling J., Sauer U., Szallasi Z., Doyle III F.J., and Doyle J. Robustness of cellular functions. Cell 118 (2004) 675-685 10.1016/j.cell.2004.09.008
    • (2004) Cell , vol.118 , pp. 675-685
    • Stelling, J.1    Sauer, U.2    Szallasi, Z.3    Doyle III, F.J.4    Doyle, J.5
  • 29
    • 77549083321 scopus 로고    scopus 로고
    • Playing hide and seek with adenosine receptors
    • 10.1111/j.1752-8062.2008.00022.x
    • Wagner D.R., and Devaux Y. Playing hide and seek with adenosine receptors. Clin. Transl. Sci. 1 (2008) 133-135 10.1111/j.1752-8062.2008.00022.x
    • (2008) Clin. Transl. Sci. , vol.1 , pp. 133-135
    • Wagner, D.R.1    Devaux, Y.2
  • 30
    • 43849083417 scopus 로고    scopus 로고
    • Sticking together? Falling apart? Exploring the dynamics of the interactome
    • 10.1016/j.tibs.2008.03.001
    • Wilkins M.R., and Kummerfeld S.K. Sticking together? Falling apart? Exploring the dynamics of the interactome. Trends Biochem. Sci. 33 (2008) 195-200 10.1016/j.tibs.2008.03.001
    • (2008) Trends Biochem. Sci. , vol.33 , pp. 195-200
    • Wilkins, M.R.1    Kummerfeld, S.K.2
  • 31
    • 50949092459 scopus 로고    scopus 로고
    • Why do hubs in the yeast protein interaction network tend to be essential: reexamining the connection between the network topology and essentiality
    • 10.1371/journal.pcbi.1000140
    • Zotenko E., Mestre J., O'Leary D.P., and Przytycka T.M. Why do hubs in the yeast protein interaction network tend to be essential: reexamining the connection between the network topology and essentiality. PLoS Comput. Biol. 4 (2008) e1000140 10.1371/journal.pcbi.1000140
    • (2008) PLoS Comput. Biol. , vol.4
    • Zotenko, E.1    Mestre, J.2    O'Leary, D.P.3    Przytycka, T.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.