Association of the manganese superoxide dismutase polymorphism with vasospastic angina pectoris

Journal of Cardiology

Volumn 55, Issue 2, 2010, Pages 205-210

  Fujimoto, Hajime ^a   Kobayashi, Hisae ^a   Ogasawara, Ken ^b   Yamakado, Minoru ^c   Ohno, Minoru ^a  

^a TORANOMON HOSPITAL   (Japan)

^b THE CARDIOVASCULAR INSTITUTE   (Japan)

^c MITSUI MEMORIAL HOSPITAL   (Japan)

Author keywords

Acetylcholine; Coronary vasospasm; Gene expression; Superoxide dismutase

Indexed keywords

ALANINE; MANGANESE SUPEROXIDE DISMUTASE; VALINE;

ADULT; AGED; AMINO ACID SUBSTITUTION; ANGINA PECTORIS; ANGIOCARDIOGRAPHY; ARTICLE; DNA POLYMORPHISM; ENDOTHELIAL DYSFUNCTION; ENZYME ACTIVITY; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; REAL TIME POLYMERASE CHAIN REACTION; VASOSPASTIC ANGINA PECTORIS;

ANGINA PECTORIS, VARIANT; FEMALE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUPEROXIDE DISMUTASE;

EID: 77549085889     PISSN: 09145087     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jjcc.2009.10.011     Document Type: Article

References (33)

1. Yasue H., Omote S., Takizawa A., and Nagao M. Coronary arterial spasm in ischemic heart disease and its pathogenesis: a review. Circ Res 52 (1983) I-147-I-152
2. Nakamura M., Takeshita A., and Nose Y. Clinical characteristics associated with myocardial infarction, arrhythmias, and sudden death in patients with vasospastic angina. Circulation 75 (1987) 1110-1116
3. Myerburg R.J., Kessler K.M., Mallon S.M., Cox M.M., DeMarchena E., Interian Jr. A., and Castellanos A. Life-threatening ventricular arrhythmias in patients with silent myocardial ischemia due to coronay artery spasm. N Engl J Med 326 (1992) 1451-1455
4. Kim M.H., Park E.H., Yang D.K., Park T.H., Kim S.G., Yoon J.H., Cha K.S., Kum D.S., Kim H.J., and Kim J.S. Role of vasospasm in acute coronary syndrome: insights from ergonovine stress echocardiography. Circ J 69 (2005) 39-43
5. Beltrame J.F., Sasayama S., and Maseri A. Racial heterogeneity in coronary artery vasomotor reactivity: differences between Japanese and Caucasian patients. J Am Coll Cardiol 33 (1999) 1442-1452
6. Pristipino C., Beltrame J.F., Finocchiaro M.L., Hattori R., Fujita M., Mongiardo R., Cianflone D., Sanna T., Sasayama S., and Maseri A. Major racial differences in coronary constrictor response between Japanese and Caucasians with recent myocardial infarction. Circulation 101 (2000) 1102-1108
7. Kugiyama K., Motoyama T., Hirashima O., Ohgushi M., Soejima H., Misumi K., Kawano H., Miyao Y., Yoshimura M., Ogawa H., Matsumura T., Sugiyama S., and Yasue H. Vitamin C attenuates abnormal vasomotor reactivity in spasm coronary arteries in patients with coronary spastic angina. J Am Coll Cardiol 32 (1998) 103-109
8. Hirashima O., Kawano H., Motoyama T., Hirai N., Ohgushi M., Kugiyama K., Ogawa H., and Yasue H. Improvement of endothelial function and insulin sensitivity with vitamin C in patients with coronary spastic angina: possible role of reactive oxygen species. J Am Coll Cardiol 35 (2000) 1860-1866
9. Motoyama T., Kawano H., Kugiyama K., Hirashima O., Ohgushi M., Tsunoda R., Moriyama Y., Miyao Y., Yoshimura M., Ogawa H., and Yasue H. Vitamin E administration improves impairment of endothelium-dependent vasodilation in patients with coronary spastic angina. J Am Coll Cardiol 32 (1998) 1672-1679
10. Wispe J.R., Clark J.C., Burhans M.S., Kropp K.E., Korfhagen T.R., and Whitsett J.A. Synthesis and processing of the precursor for human mangano-superoxide dismutase. Biochim Biophys Acta 994 (1989) 30-36
11. Shimoda-Matsubayashi S., Matsumine H., Kobayashi T., Nakagawa-Hattori Y., Shimizu Y., and Mizuno Y. Structural dimorphism in the mitochondrial targeting sequence in the human manganese superoxide dismutase gene. A predictive evidence for conformational change to influence mitochondrial transport and a study of allelic association in Parkinson's disease. Biochem Biophys Res Commun 226 (1996) 561-565
12. Ohashi M., Runge M.S., Faraci F.M., and Heistad D.D. MnSOD deficiency increases endothelial dysfunction in ApoE-deficient mice. Arterioscler Thromb Vasc Biol 26 (2006) 2331-2336
13. Fang X., Weintraub N.L., Rios C.D., Chappell D.A., Zwacka R.M., Engelhardt J.F., Oberley L.W., Yan T., Heistad D.D., and Spector A.A. Overexpression of human superoxide dismutase inhibits oxidation of low-density lipoprotein by endothelial cells. Circ Res 82 (1998) 1289-1297
14. Kinscherf R., Claus R., Wagner M., Gehrke C., Kamencic H., Hou D., Nauen O., Schmiedt W., Kovacs G., Pill J., Metz J., and Deigner H.P. Apoptosis caused by oxidized LDL is manganese superoxide dismutase and p53 dependent. FASEB J 6 (1998) 461-467
15. Shatrov V.A., and Brune B. Induced expression of manganese superoxide dismutase by non-toxic concentrations of oxidized low-density lipoprotein (oxLDL) protects against oxLDL-mediated cytotoxicity. Biochem J 374 (2003) 505-511
16. Fujimoto H., Taguchi J., Imai Y., Ayabe S., Hashimoto H., Kobayashi H., Ogasawara K., Aizawa T., Yamakado M., Nagai R., and Ohno M. Manganese superoxide dismutase polymorphism affects the oxidized low-density lipoprotein-induced apoptosis of macrophages and coronary artery disease. Eur Heart J 29 (2008) 1267-1274
17. Rosenblum J.S., Gilula N.B., and Lerner R.A. On signal sequence polymorphisms and diseases of distribution. Proc Natl Acad Sci USA 93 (1996) 4471-4473
18. Hiroi S., Harada H., Nishi H., Satoh M., Nagai R., and Kimura A. Polymorphisms in the SOD2 and HLA-DRB1 genes are associated with nonfamilial idiopathic dilated cardiomyopathy in Japanese. Biochem Biophys Res Commun 261 (1999) 332-339
19. Yoshimura M., Yasue H., Nakayama M., Shimasaki Y., Sumida H., Sugiyama S., Kugiyama K., Ogawa H., Ogawa Y., Saito Y., Miyamoto Y., and Nakao K. A missense Glu298Asp variant in the endothelial nitric oxide synthase gene is associated with coronary spasm in the Japanese. Hum Genet 103 (1998) 65-69
20. Nakayama M., Yasue H., Yoshimura M., Shimasaki Y., Kugiyama K., Ogawa H., Motoyama T., Saito Y., Ogawa Y., Miyamoto Y., and Nakao K. T-786 → C mutation in the 5′-flanking region of the endothelial nitric oxide synthase gene is associated with coronary spasm. Circulation 99 (1999) 2864-2870
21. Ito T., Yasue H., Yoshimura M., Nakamura S., Nakayama M., Shimasaki Y., Harada E., Mizuno Y., Kawano H., and Ogawa H. Paraoxonase gene Gln192Arg (Q192R) polymorphism is associated with coronary artery spasm. Hum Genet 110 (2002) 89-94
22. Mashiba J., Koike G., Kamiunten H., Ikeda M., and Sunagawa K. Vasospastic angina and microvascular angina are differentially influenced by PON1 A632G polymorphism in the Japanese. Circ J 69 (2005) 1466-1471
23. Kaneda H., Taguchi J., Kuwada Y., Hangaishi M., Aizawa T., Yamakado M., Ogasawara K., Aizawa T., and Ohno M. Coronary artery spasm and the polymorphisms of the endothelial nitric oxide synthase gene. Circ J 70 (2006) 409-413
24. Sugiishi M., and Takatsu F. Cigarette smoking is a major risk factor for coronary spasm. Circulation 87 (1993) 76-79
25. Yasue H., Nakagawa H., Itoh T., Harada E., and Mizuno Y. Coronary artery spasm-clinical features, diagnosis, pathogenesis, and treatment. J Cardiol 51 (2008) 2-17
26. Rubanyi G.M. The role of endothelium in cardiovascular homeostasis and diseases. J Cardiovasc Pharmacol 22 (1993) S1-14
27. Egashira K., Inou T., Yamada A., Hirooka Y., and Takeshita A. Preserved endothelium-dependent vasodilation at the vasospastic site in patients with variant angina. J Clin Invest 89 (1992) 1047-1052
28. Bräsen J.H., Leppänen O., Inkala M., Heikura T., Levin M., Ahrens F., Rutanen J., Rutanen J., Pietsch H., Bergqvist D., Levonen A.L., Basu S., Zeller T., Klöppel G., Laukkanen M.O., et al. Extracellular superoxide dismutase accelerates endothelial recovery and inhibits in-stent restenosis in stented atherosclerotic Watanabe heritable hyperlipidemic rabbit aorta. J Am Coll Cardiol 50 (2007) 2249-2253
29. Lund D.D., Chu Y., Brooks R.M., Faraci F.M., and Heistad D.D. Effects of a common human gene variant of extracellular superoxide dismutase on endothelial function after endotoxin in mice. J Physiol 584 (2007) 583-590
30. Shuvaev V.V., Tliba S., Nakada M., Albelda S.M., and Muzykantov V.R. Platelet-endothelial cell adhesion molecule-1-directed endothelial targeting of superoxide dismutase alleviates oxidative stress caused by either extracellular or intracellular superoxide. J Pharmacol Exp Ther 323 (2007) 450-457
31. Giardina J.B., Tanner D.J., Khalil R.A., and Oxidized-LDL. enhances coronary vasoconstriction by increasing the activity of protein kinase C isoforms alpha and epsilon. Hypertension 37 (2001) 561-568
32. Miwa K., Fujita M., and Sasayama S. Recent insights into the mechanisms, predisposing factors, and racial differences of coronary vasospasm. Heart Vessels 20 (2005) 1-7
33. Shimokawa H., and Takeshita A. Rho-kinase is an important therapeutic target in cardiovascular medicine. Arterioscler Thromb Vasc Biol 25 (2005) 1767-1775