Synthesis of fluorinated C-mannopeptides as sialyl Lewisx mimics for E- and P-selectin inhibition

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 6, 2010, Pages 1957-1960

  Gouge Ibert, Vanessa ^a   Pierry, Camille ^a   Poulain, Florent ^a   Serre, Anne Lise ^a   Largeau, Céline ^b,c,d,e   Escriou, Virginie ^b,c,d,e   Scherman, Daniel ^b,c,d,e   Jubault, Philippe ^a   Quirion, Jean Charles ^a   Leclerc, Eric ^a  

^a UNIVERSITÉ ET INSA DE ROUEN   (France)

^b INSERM   (France)

^c CNRS   (France)

^d UNIVERSITÉ PARIS DESCARTES   (France)

^e PSL RESEARCH UNIVERSITY   (France)

Author keywords

C Glycosides; Fluorine; Selectin inhibitors; sLex Mimics

Indexed keywords

C MANNOPEPTIDE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; GLYCOPEPTIDE; MANNOSIDE; PADGEM PROTEIN; PEPTIDE DERIVATIVE; SIALYL LEWIS X ANTIGEN; UNCLASSIFIED DRUG;

ARTICLE; EVALUATION; FLUORINATION; INHIBITION KINETICS; MOLECULE; SYNTHESIS;

E-SELECTIN; FLUORINE; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR MIMICRY; OLIGOSACCHARIDES; P-SELECTIN; PEPTIDES;

EID: 77549084150     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.01.141     Document Type: Article

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