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Volumn 166, Issue 3, 2010, Pages 924-934

NMDA receptors in primary afferents require phosphorylation by Src family kinases to induce substance P release in the rat spinal cord

Author keywords

C fiber; dorsal horn; internalization; neurokinin 1 receptor; nociceptor; protein tyrosine phosphatase

Indexed keywords

2 BENZHYDRYL 3 (2 IODOBENZYLAMINO)QUINUCLIDINE; 4 AMINO 7 TERT BUTYL 5 (4 METHYLPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; CALCIUM ION; CAPSAICIN; DASATINIB; DEXTRO SERINE; DIZOCILPINE; IFENPRODIL; LIDOCAINE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; NEUROKININ 1 RECEPTOR; OMEGA CONOTOXIN MVIIA; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE INHIBITOR; SODIUM CHANNEL; SUBSTANCE P; VOLTAGE GATED CALCIUM CHANNEL;

EID: 77549083670     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2010.01.009     Document Type: Article
Times cited : (26)

References (72)
  • 1
    • 0030798999 scopus 로고    scopus 로고
    • Inflammation increases the distribution of dorsal horn neurons that internalize the neurokinin-1 receptor in response to noxious and non-noxious stimulation
    • Abbadie C., Trafton J., Liu H., Mantyh P.W., and Basbaum A.I. Inflammation increases the distribution of dorsal horn neurons that internalize the neurokinin-1 receptor in response to noxious and non-noxious stimulation. J Neurosci 17 (1997) 8049-8060
    • (1997) J Neurosci , vol.17 , pp. 8049-8060
    • Abbadie, C.1    Trafton, J.2    Liu, H.3    Mantyh, P.W.4    Basbaum, A.I.5
  • 3
    • 67349236670 scopus 로고    scopus 로고
    • Substance P release and neurokinin 1 receptor activation in the rat spinal cord increases with the firing frequency of C-fibers
    • Adelson D.W., Lao L., Zhang G., Kim W., and Marvizón J.C. Substance P release and neurokinin 1 receptor activation in the rat spinal cord increases with the firing frequency of C-fibers. Neuroscience 161 (2009) 538-553
    • (2009) Neuroscience , vol.161 , pp. 538-553
    • Adelson, D.W.1    Lao, L.2    Zhang, G.3    Kim, W.4    Marvizón, J.C.5
  • 4
    • 0035910042 scopus 로고    scopus 로고
    • Involvement of spinal N-methyl-d-aspartate receptors in capsaicin-induced in vivo release of substance P in the rat dorsal horn
    • Afrah A.W., Stiller C.O., Olgart L., Brodin E., and Gustafsson H. Involvement of spinal N-methyl-d-aspartate receptors in capsaicin-induced in vivo release of substance P in the rat dorsal horn. Neurosci Lett 316 (2001) 83-86
    • (2001) Neurosci Lett , vol.316 , pp. 83-86
    • Afrah, A.W.1    Stiller, C.O.2    Olgart, L.3    Brodin, E.4    Gustafsson, H.5
  • 5
    • 0032978019 scopus 로고    scopus 로고
    • Primary afferent fibers that contribute to increased substance P receptor internalization in the spinal cord after injury
    • Allen B.J., Li J., Menning P.M., Rogers S.D., Ghilardi J., Mantyh P.W., and Simone D.A. Primary afferent fibers that contribute to increased substance P receptor internalization in the spinal cord after injury. J Neurophysiol 81 (1999) 1379-1390
    • (1999) J Neurophysiol , vol.81 , pp. 1379-1390
    • Allen, B.J.1    Li, J.2    Menning, P.M.3    Rogers, S.D.4    Ghilardi, J.5    Mantyh, P.W.6    Simone, D.A.7
  • 6
    • 0030877822 scopus 로고    scopus 로고
    • Noxious cutaneous thermal stimuli induce a graded release of endogenous substance P in the spinal cord: imaging peptide action in vivo
    • Allen B.J., Rogers S.D., Ghilardi J.R., Menning P.M., Kuskowski M.A., Basbaum A.I., Simone D.A., and Mantyh P.W. Noxious cutaneous thermal stimuli induce a graded release of endogenous substance P in the spinal cord: imaging peptide action in vivo. J Neurosci 17 (1997) 5921-5927
    • (1997) J Neurosci , vol.17 , pp. 5921-5927
    • Allen, B.J.1    Rogers, S.D.2    Ghilardi, J.R.3    Menning, P.M.4    Kuskowski, M.A.5    Basbaum, A.I.6    Simone, D.A.7    Mantyh, P.W.8
  • 7
    • 17044446594 scopus 로고    scopus 로고
    • Antagonist properties of the stereoisomers of ifenprodil at NR1A/NR2A and NR1A/NR2B subtypes of the NMDA receptor expressed in Xenopus oocytes
    • Avenet P., Leonardon J., Besnard F., Graham D., Frost J., Depoortere H., Langer S.Z., and Scatton B. Antagonist properties of the stereoisomers of ifenprodil at NR1A/NR2A and NR1A/NR2B subtypes of the NMDA receptor expressed in Xenopus oocytes. Eur J Pharmacol 296 (1996) 209-213
    • (1996) Eur J Pharmacol , vol.296 , pp. 209-213
    • Avenet, P.1    Leonardon, J.2    Besnard, F.3    Graham, D.4    Frost, J.5    Depoortere, H.6    Langer, S.Z.7    Scatton, B.8
  • 8
    • 1642407670 scopus 로고    scopus 로고
    • Presynaptic NMDA receptors modulate glutamate release from primary sensory neurons in rat spinal cord dorsal horn
    • Bardoni R., Torsney C., Tong C.K., Prandini M., and MacDermott A.B. Presynaptic NMDA receptors modulate glutamate release from primary sensory neurons in rat spinal cord dorsal horn. J Neurosci 24 (2004) 2774-2781
    • (2004) J Neurosci , vol.24 , pp. 2774-2781
    • Bardoni, R.1    Torsney, C.2    Tong, C.K.3    Prandini, M.4    MacDermott, A.B.5
  • 9
    • 0032987252 scopus 로고    scopus 로고
    • Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: correlation with restricted localisation of NR2B subunit in dorsal horn
    • Boyce S., Wyatt A., Webb J.K., O'Donnell R., Mason G., Rigby M., Sirinathsinghji D., Hill R.G., and Rupniak N.M. Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: correlation with restricted localisation of NR2B subunit in dorsal horn. Neuropharmacology 38 (1999) 611-623
    • (1999) Neuropharmacology , vol.38 , pp. 611-623
    • Boyce, S.1    Wyatt, A.2    Webb, J.K.3    O'Donnell, R.4    Mason, G.5    Rigby, M.6    Sirinathsinghji, D.7    Hill, R.G.8    Rupniak, N.M.9
  • 11
    • 0001899259 scopus 로고
    • Structural elements which determine local anesthetic activity
    • Born G.V., Farah A., Herken H., and Welch A.D. (Eds), Springer-Verlag, New York
    • Courtney K.R., Strichartz G.R., and Strichartz G.R. Structural elements which determine local anesthetic activity. In: Born G.V., Farah A., Herken H., and Welch A.D. (Eds). Local anesthetics (1987), Springer-Verlag, New York 53-94
    • (1987) Local anesthetics , pp. 53-94
    • Courtney, K.R.1    Strichartz, G.R.2    Strichartz, G.R.3
  • 14
    • 0029871365 scopus 로고    scopus 로고
    • Interactions between ifenprodil and the NR2B subunit of the N-methyl-d-aspartate receptor
    • Gallagher M.J., Huang H., Pritchett D.B., and Lynch D.R. Interactions between ifenprodil and the NR2B subunit of the N-methyl-d-aspartate receptor. J Biol Chem 271 (1996) 9603-9611
    • (1996) J Biol Chem , vol.271 , pp. 9603-9611
    • Gallagher, M.J.1    Huang, H.2    Pritchett, D.B.3    Lynch, D.R.4
  • 15
    • 60349088785 scopus 로고    scopus 로고
    • Phospho-regulation of synaptic and extrasynaptic N-methyl-d-aspartate receptors in adult hippocampal slices
    • Goebel-Goody S.M., Davies K.D., Alvestad Linger R.M., Freund R.K., and Browning M.D. Phospho-regulation of synaptic and extrasynaptic N-methyl-d-aspartate receptors in adult hippocampal slices. Neuroscience 158 (2009) 1446-1459
    • (2009) Neuroscience , vol.158 , pp. 1446-1459
    • Goebel-Goody, S.M.1    Davies, K.D.2    Alvestad Linger, R.M.3    Freund, R.K.4    Browning, M.D.5
  • 16
    • 10244242550 scopus 로고    scopus 로고
    • Characterization of antisera specific to NK1, NK2, and NK3 neurokinin receptors and their utilization to localize receptors in the rat gastrointestinal tract
    • Grady E.F., Baluk P., Bohm S., Gamp P.D., Wong H., Payan D.G., Ansel J., Portbury A.L., Furness J.B., McDonald D.M., and Bunnett N.W. Characterization of antisera specific to NK1, NK2, and NK3 neurokinin receptors and their utilization to localize receptors in the rat gastrointestinal tract. J Neurosci 16 (1996) 6975-6986
    • (1996) J Neurosci , vol.16 , pp. 6975-6986
    • Grady, E.F.1    Baluk, P.2    Bohm, S.3    Gamp, P.D.4    Wong, H.5    Payan, D.G.6    Ansel, J.7    Portbury, A.L.8    Furness, J.B.9    McDonald, D.M.10    Bunnett, N.W.11
  • 17
    • 0030029143 scopus 로고    scopus 로고
    • Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation
    • Hanke J.H., Gardner J.P., Dow R.L., Changelian P.S., Brissette W.H., Weringer E.J., Pollok B.A., and Connelly P.A. Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation. J Biol Chem 271 (1996) 695-701
    • (1996) J Biol Chem , vol.271 , pp. 695-701
    • Hanke, J.H.1    Gardner, J.P.2    Dow, R.L.3    Changelian, P.S.4    Brissette, W.H.5    Weringer, E.J.6    Pollok, B.A.7    Connelly, P.A.8
  • 19
    • 0033179318 scopus 로고    scopus 로고
    • Evidence for tonic activation of NK-1 receptors during the second phase of the formalin test in the rat
    • Henry J.L., Yashpal K., Pitcher G.M., Chabot J., and Coderre T.J. Evidence for tonic activation of NK-1 receptors during the second phase of the formalin test in the rat. J Neurosci 19 (1999) 6588-6598
    • (1999) J Neurosci , vol.19 , pp. 6588-6598
    • Henry, J.L.1    Yashpal, K.2    Pitcher, G.M.3    Chabot, J.4    Coderre, T.J.5
  • 21
    • 0033197997 scopus 로고    scopus 로고
    • Spinal cord substance P receptor expression and internalization in acute, short-term, and long-term inflammatory pain states
    • Honore P., Menning P.M., Rogers S.D., Nichols M.L., Basbaum A.I., Besson J.M., and Mantyh P.W. Spinal cord substance P receptor expression and internalization in acute, short-term, and long-term inflammatory pain states. J Neurosci 19 (1999) 7670-7678
    • (1999) J Neurosci , vol.19 , pp. 7670-7678
    • Honore, P.1    Menning, P.M.2    Rogers, S.D.3    Nichols, M.L.4    Basbaum, A.I.5    Besson, J.M.6    Mantyh, P.W.7
  • 22
    • 7944234850 scopus 로고    scopus 로고
    • Src in synaptic transmission and plasticity
    • Kalia L.V., Gingrich J.R., and Salter M.W. Src in synaptic transmission and plasticity. Oncogene 23 (2004) 8007-8016
    • (2004) Oncogene , vol.23 , pp. 8007-8016
    • Kalia, L.V.1    Gingrich, J.R.2    Salter, M.W.3
  • 24
    • 0034036363 scopus 로고    scopus 로고
    • Deficits in visceral pain and hyperalgesia of mice with a disruption of the tachykinin NK1 receptor gene
    • Laird J.M., Olivar T., Roza C., De Felipe C., Hunt S.P., and Cervero F. Deficits in visceral pain and hyperalgesia of mice with a disruption of the tachykinin NK1 receptor gene. Neuroscience 98 (2000) 345-352
    • (2000) Neuroscience , vol.98 , pp. 345-352
    • Laird, J.M.1    Olivar, T.2    Roza, C.3    De Felipe, C.4    Hunt, S.P.5    Cervero, F.6
  • 25
    • 0035252574 scopus 로고    scopus 로고
    • Role of central and peripheral tachykinin NK1 receptors in capsaicin-induced pain and hyperalgesia in mice
    • Laird J.M., Roza C., De Felipe C., Hunt S.P., and Cervero F. Role of central and peripheral tachykinin NK1 receptors in capsaicin-induced pain and hyperalgesia in mice. Pain 90 (2001) 97-103
    • (2001) Pain , vol.90 , pp. 97-103
    • Laird, J.M.1    Roza, C.2    De Felipe, C.3    Hunt, S.P.4    Cervero, F.5
  • 26
    • 11844269872 scopus 로고    scopus 로고
    • A receptor facilitation of neurokinin release from primary afferent terminals in the rat spinal cord
    • A receptor facilitation of neurokinin release from primary afferent terminals in the rat spinal cord. Neuroscience 130 (2005) 1013-1027
    • (2005) Neuroscience , vol.130 , pp. 1013-1027
    • Lao, L.1    Marvizon, J.C.G.2
  • 28
    • 2442628592 scopus 로고    scopus 로고
    • Electrophysiological characterization of N-methyl-d-aspartate receptors in rat dorsal root ganglia neurons
    • Li J., McRoberts J.A., Nie J., Ennes H.S., and Mayer E.A. Electrophysiological characterization of N-methyl-d-aspartate receptors in rat dorsal root ganglia neurons. Pain 109 (2004) 443-452
    • (2004) Pain , vol.109 , pp. 443-452
    • Li, J.1    McRoberts, J.A.2    Nie, J.3    Ennes, H.S.4    Mayer, E.A.5
  • 30
    • 2142652107 scopus 로고    scopus 로고
    • Oxidation of protein tyrosine phosphatases as a pharmaceutical mechanism of action: a study using 4-hydroxy-3,3-dimethyl-2H-benzo[g]indole-2,5(3H)-dione
    • Liljebris C., Baranczewski P., Bjorkstrand E., Bystrom S., Lundgren B., Tjernberg A., Warolen M., and James S.R. Oxidation of protein tyrosine phosphatases as a pharmaceutical mechanism of action: a study using 4-hydroxy-3,3-dimethyl-2H-benzo[g]indole-2,5(3H)-dione. J Pharmacol Exp Ther 309 (2004) 711-719
    • (2004) J Pharmacol Exp Ther , vol.309 , pp. 711-719
    • Liljebris, C.1    Baranczewski, P.2    Bjorkstrand, E.3    Bystrom, S.4    Lundgren, B.5    Tjernberg, A.6    Warolen, M.7    James, S.R.8
  • 31
    • 0030943255 scopus 로고    scopus 로고
    • NMDA-receptor regulation of substance P release from primary afferent nociceptors
    • Liu H., Mantyh P.W., and Basbaum A.I. NMDA-receptor regulation of substance P release from primary afferent nociceptors. Nature 386 (1997) 721-724
    • (1997) Nature , vol.386 , pp. 721-724
    • Liu, H.1    Mantyh, P.W.2    Basbaum, A.I.3
  • 32
    • 0028023153 scopus 로고
    • Evidence for presynaptic N-methyl-d-aspartate autoreceptors in the spinal cord dorsal horn
    • Liu H., Wang H., Sheng M., Jan L.Y., Jan Y.N., and Basbaum A.I. Evidence for presynaptic N-methyl-d-aspartate autoreceptors in the spinal cord dorsal horn. Proc Natl Acad Sci U S A 91 (1994) 8383-8387
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 8383-8387
    • Liu, H.1    Wang, H.2    Sheng, M.3    Jan, L.Y.4    Jan, Y.N.5    Basbaum, A.I.6
  • 34
    • 0023768328 scopus 로고
    • Glutamate induces a depolarization of adult rat dorsal root ganglion neurons that is mediated predominantly by NMDA receptors
    • Lovinger D.M., and Weight F.F. Glutamate induces a depolarization of adult rat dorsal root ganglion neurons that is mediated predominantly by NMDA receptors. Neurosci Lett 94 (1988) 314-320
    • (1988) Neurosci Lett , vol.94 , pp. 314-320
    • Lovinger, D.M.1    Weight, F.F.2
  • 35
    • 0242417529 scopus 로고    scopus 로고
    • Primary afferent terminals that express presynaptic NR1 in rats are mainly from myelinated, mechanosensitive fibers
    • Lu C.R., Hwang S.J., Phend K.D., Rustioni A., and Valtschanoff J.G. Primary afferent terminals that express presynaptic NR1 in rats are mainly from myelinated, mechanosensitive fibers. J Comp Neurol 460 (2003) 191-202
    • (2003) J Comp Neurol , vol.460 , pp. 191-202
    • Lu, C.R.1    Hwang, S.J.2    Phend, K.D.3    Rustioni, A.4    Valtschanoff, J.G.5
  • 36
    • 0034669122 scopus 로고    scopus 로고
    • Localization of N-methyl-d-aspartate NR2B subunits on primary sensory neurons that give rise to small-caliber sciatic nerve fibers in rats
    • Ma Q.P., and Hargreaves R.J. Localization of N-methyl-d-aspartate NR2B subunits on primary sensory neurons that give rise to small-caliber sciatic nerve fibers in rats. Neuroscience 101 (2000) 699-707
    • (2000) Neuroscience , vol.101 , pp. 699-707
    • Ma, Q.P.1    Hargreaves, R.J.2
  • 37
    • 0032421805 scopus 로고    scopus 로고
    • NMDA receptor activation modulates evoked release of substance P from rat spinal cord
    • Malcangio M., Fernandes K., and Tomlinson D.R. NMDA receptor activation modulates evoked release of substance P from rat spinal cord. Br J Pharmacol 125 (1998) 1625-1626
    • (1998) Br J Pharmacol , vol.125 , pp. 1625-1626
    • Malcangio, M.1    Fernandes, K.2    Tomlinson, D.R.3
  • 40
    • 0030731433 scopus 로고    scopus 로고
    • Neurokinin 1 receptor internalization in spinal cord slices induced by dorsal root stimulation is mediated by NMDA receptors
    • Marvizon J.C., Martinez V., Grady E.F., Bunnett N.W., and Mayer E.A. Neurokinin 1 receptor internalization in spinal cord slices induced by dorsal root stimulation is mediated by NMDA receptors. J Neurosci 17 (1997) 8129-8136
    • (1997) J Neurosci , vol.17 , pp. 8129-8136
    • Marvizon, J.C.1    Martinez, V.2    Grady, E.F.3    Bunnett, N.W.4    Mayer, E.A.5
  • 41
    • 0032970296 scopus 로고    scopus 로고
    • Substance P release in the dorsal horn assessed by receptor internalization: NMDA receptors counteract a tonic inhibition by GABA(B) receptors
    • Marvizon J.C., Grady E.F., Stefani E., Bunnett N.W., and Mayer E.A. Substance P release in the dorsal horn assessed by receptor internalization: NMDA receptors counteract a tonic inhibition by GABA(B) receptors. Eur J Neurosci 11 (1999) 417-426
    • (1999) Eur J Neurosci , vol.11 , pp. 417-426
    • Marvizon, J.C.1    Grady, E.F.2    Stefani, E.3    Bunnett, N.W.4    Mayer, E.A.5
  • 43
    • 0037426616 scopus 로고    scopus 로고
    • Relationship between capsaicin-evoked substance P release and neurokinin 1 receptor internalization in the rat spinal cord
    • Marvizon J.C., Wang X., Matsuka Y., Neubert J.K., and Spigelman I. Relationship between capsaicin-evoked substance P release and neurokinin 1 receptor internalization in the rat spinal cord. Neuroscience 118 (2003) 535-545
    • (2003) Neuroscience , vol.118 , pp. 535-545
    • Marvizon, J.C.1    Wang, X.2    Matsuka, Y.3    Neubert, J.K.4    Spigelman, I.5
  • 44
    • 0346688591 scopus 로고    scopus 로고
    • Effect of peptidases on the ability of exogenous and endogenous neurokinins to produce neurokinin 1 receptor internalization in the rat spinal cord
    • Marvizon J.C.G., Wang X., Lao L., and Song B. Effect of peptidases on the ability of exogenous and endogenous neurokinins to produce neurokinin 1 receptor internalization in the rat spinal cord. Br J Pharmacol 140 (2003) 1389-1398
    • (2003) Br J Pharmacol , vol.140 , pp. 1389-1398
    • Marvizon, J.C.G.1    Wang, X.2    Lao, L.3    Song, B.4
  • 45
    • 0029864403 scopus 로고    scopus 로고
    • Inhibition of calcium channels in rat central and peripheral neurons by omega-conotoxin MVIIC
    • McDonough S.I., Swartz K.J., Mintz I.M., Boland L.M., and Bean B.P. Inhibition of calcium channels in rat central and peripheral neurons by omega-conotoxin MVIIC. J Neurosci 16 (1996) 2612-2623
    • (1996) J Neurosci , vol.16 , pp. 2612-2623
    • McDonough, S.I.1    Swartz, K.J.2    Mintz, I.M.3    Boland, L.M.4    Bean, B.P.5
  • 46
    • 34548791634 scopus 로고    scopus 로고
    • Sex-dependent differences in the activity and modulation of N-methyl-d-aspartic acid receptors in rat dorsal root ganglia neurons
    • McRoberts J.A., Li J., Ennes H.S., and Mayer E.A. Sex-dependent differences in the activity and modulation of N-methyl-d-aspartic acid receptors in rat dorsal root ganglia neurons. Neuroscience 148 (2007) 1015-1020
    • (2007) Neuroscience , vol.148 , pp. 1015-1020
    • McRoberts, J.A.1    Li, J.2    Ennes, H.S.3    Mayer, E.A.4
  • 48
    • 10944258479 scopus 로고    scopus 로고
    • Synaptic distribution of the NR1, NR2A and NR2B subunits of the N-methyl-d-aspartate receptor in the rat lumbar spinal cord revealed with an antigen-unmasking technique
    • Nagy G.G., Watanabe M., Fukaya M., and Todd A.J. Synaptic distribution of the NR1, NR2A and NR2B subunits of the N-methyl-d-aspartate receptor in the rat lumbar spinal cord revealed with an antigen-unmasking technique. Eur J Neurosci 20 (2004) 3301-3312
    • (2004) Eur J Neurosci , vol.20 , pp. 3301-3312
    • Nagy, G.G.1    Watanabe, M.2    Fukaya, M.3    Todd, A.J.4
  • 50
    • 33847198227 scopus 로고    scopus 로고
    • Alternative splicing controls G protein-dependent inhibition of N-type calcium channels in nociceptors
    • Raingo J., Castiglioni A.J., and Lipscombe D. Alternative splicing controls G protein-dependent inhibition of N-type calcium channels in nociceptors. Nat Neurosci 10 (2007) 285-292
    • (2007) Nat Neurosci , vol.10 , pp. 285-292
    • Raingo, J.1    Castiglioni, A.J.2    Lipscombe, D.3
  • 51
    • 0035925692 scopus 로고    scopus 로고
    • Presynaptic regulation of spinal cord tachykinin signaling via GABA(B) but not GABA(A) receptor activation
    • Riley R.C., Trafton J.A., Chi S.I., and Basbaum A.I. Presynaptic regulation of spinal cord tachykinin signaling via GABA(B) but not GABA(A) receptor activation. Neuroscience 103 (2001) 725-737
    • (2001) Neuroscience , vol.103 , pp. 725-737
    • Riley, R.C.1    Trafton, J.A.2    Chi, S.I.3    Basbaum, A.I.4
  • 52
    • 0028981596 scopus 로고
    • mu-Opioid receptor activation reduces multiple components of high-threshold calcium current in rat sensory neurons
    • Rusin K.I., and Moises H.C. mu-Opioid receptor activation reduces multiple components of high-threshold calcium current in rat sensory neurons. J Neurosci 15 (1995) 4315-4327
    • (1995) J Neurosci , vol.15 , pp. 4315-4327
    • Rusin, K.I.1    Moises, H.C.2
  • 53
    • 0031900694 scopus 로고    scopus 로고
    • 2+ currents in rat nodose ganglion neurons
    • 2+ currents in rat nodose ganglion neurons. Neuroscience 85 (1998) 939-956
    • (1998) Neuroscience , vol.85 , pp. 939-956
    • Rusin, K.I.1    Moises, H.C.2
  • 54
    • 0027421810 scopus 로고
    • AMPA, KA and NMDA receptors are expressed in the rat DRG neurones
    • Sato K., Kiyama H., Park H.T., and Tohyama M. AMPA, KA and NMDA receptors are expressed in the rat DRG neurones. Neuroreport 4 (1993) 1263-1265
    • (1993) Neuroreport , vol.4 , pp. 1263-1265
    • Sato, K.1    Kiyama, H.2    Park, H.T.3    Tohyama, M.4
  • 55
    • 43049112058 scopus 로고    scopus 로고
    • Post-synaptic density-93 mediates tyrosine-phosphorylation of the N-methyl-d-aspartate receptors
    • Sato Y., Tao Y.X., Su Q., and Johns R.A. Post-synaptic density-93 mediates tyrosine-phosphorylation of the N-methyl-d-aspartate receptors. Neuroscience 153 (2008) 700-708
    • (2008) Neuroscience , vol.153 , pp. 700-708
    • Sato, Y.1    Tao, Y.X.2    Su, Q.3    Johns, R.A.4
  • 56
    • 31544459272 scopus 로고    scopus 로고
    • Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human malignancies
    • Schittenhelm M.M., Shiraga S., Schroeder A., Corbin A.S., Griffith D., Lee F.Y., Bokemeyer C., Deininger M.W., Druker B.J., and Heinrich M.C. Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human malignancies. Cancer Res 66 (2006) 473-481
    • (2006) Cancer Res , vol.66 , pp. 473-481
    • Schittenhelm, M.M.1    Shiraga, S.2    Schroeder, A.3    Corbin, A.S.4    Griffith, D.5    Lee, F.Y.6    Bokemeyer, C.7    Deininger, M.W.8    Druker, B.J.9    Heinrich, M.C.10
  • 57
    • 0141885141 scopus 로고    scopus 로고
    • Dorsal horn neurons firing at high frequency, but not primary afferents, release opioid peptides that produce m-opioid receptor internalization in the rat spinal cord
    • Song B., and Marvizon J.C.G. Dorsal horn neurons firing at high frequency, but not primary afferents, release opioid peptides that produce m-opioid receptor internalization in the rat spinal cord. J Neurosci 23 (2003) 9171-9184
    • (2003) J Neurosci , vol.23 , pp. 9171-9184
    • Song, B.1    Marvizon, J.C.G.2
  • 58
    • 27744492907 scopus 로고    scopus 로고
    • NMDA receptors and large conductance calcium-sensitive potassium channels inhibit the release of opioid peptides that induce m-opioid receptor internalization in the rat spinal cord
    • Song B., and Marvizon J.C.G. NMDA receptors and large conductance calcium-sensitive potassium channels inhibit the release of opioid peptides that induce m-opioid receptor internalization in the rat spinal cord. Neuroscience 136 (2005) 549-562
    • (2005) Neuroscience , vol.136 , pp. 549-562
    • Song, B.1    Marvizon, J.C.G.2
  • 59
    • 0037095729 scopus 로고    scopus 로고
    • Projection neurons in lamina I of rat spinal cord with the neurokinin 1 receptor are selectively innervated by substance P-containing afferents and respond to noxious stimulation
    • Todd A.J., Puskar Z., Spike R.C., Hughes C., Watt C., and Forrest L. Projection neurons in lamina I of rat spinal cord with the neurokinin 1 receptor are selectively innervated by substance P-containing afferents and respond to noxious stimulation. J Neurosci 22 (2002) 4103-4113
    • (2002) J Neurosci , vol.22 , pp. 4103-4113
    • Todd, A.J.1    Puskar, Z.2    Spike, R.C.3    Hughes, C.4    Watt, C.5    Forrest, L.6
  • 60
    • 12844266086 scopus 로고    scopus 로고
    • Fos induction in lamina I projection neurons in response to noxious thermal stimuli
    • Todd A.J., Spike R.C., Young S., and Puskar Z. Fos induction in lamina I projection neurons in response to noxious thermal stimuli. Neuroscience 131 (2005) 209-217
    • (2005) Neuroscience , vol.131 , pp. 209-217
    • Todd, A.J.1    Spike, R.C.2    Young, S.3    Puskar, Z.4
  • 61
    • 0035873496 scopus 로고    scopus 로고
    • Differential contribution of substance P and neurokinin A to spinal cord neurokinin-1 receptor signaling in the rat
    • Trafton J.A., Abbadie C., and Basbaum A.I. Differential contribution of substance P and neurokinin A to spinal cord neurokinin-1 receptor signaling in the rat. J Neurosci 21 (2001) 3656-3664
    • (2001) J Neurosci , vol.21 , pp. 3656-3664
    • Trafton, J.A.1    Abbadie, C.2    Basbaum, A.I.3
  • 62
    • 0033232528 scopus 로고    scopus 로고
    • Spinal opioid analgesia: how critical is the regulation of substance P signaling?
    • Trafton J.A., Abbadie C., Marchand S., Mantyh P.W., and Basbaum A.I. Spinal opioid analgesia: how critical is the regulation of substance P signaling?. J Neurosci 19 (1999) 9642-9653
    • (1999) J Neurosci , vol.19 , pp. 9642-9653
    • Trafton, J.A.1    Abbadie, C.2    Marchand, S.3    Mantyh, P.W.4    Basbaum, A.I.5
  • 63
    • 0030246892 scopus 로고    scopus 로고
    • The spinal contribution of substance P to the generation and maintenance of inflammatory hyperalgesia in the rat
    • Traub R.J. The spinal contribution of substance P to the generation and maintenance of inflammatory hyperalgesia in the rat. Pain 67 (1996) 151-161
    • (1996) Pain , vol.67 , pp. 151-161
    • Traub, R.J.1
  • 64
    • 0035167454 scopus 로고    scopus 로고
    • A workingperson's guide to deconvolution in light microscopy
    • Wallace W., Schaefer L.H., and Swedlow J.R. A workingperson's guide to deconvolution in light microscopy. Biotechniques 31 (2001) 1076-1078
    • (2001) Biotechniques , vol.31 , pp. 1076-1078
    • Wallace, W.1    Schaefer, L.H.2    Swedlow, J.R.3
  • 65
    • 0037135181 scopus 로고    scopus 로고
    • Time-course of the internalization and recycling of neurokinin 1 receptors in rat dorsal horn neurons
    • Wang X., and Marvizon J.C. Time-course of the internalization and recycling of neurokinin 1 receptors in rat dorsal horn neurons. Brain Res 944 (2002) 239-247
    • (2002) Brain Res , vol.944 , pp. 239-247
    • Wang, X.1    Marvizon, J.C.2
  • 66
    • 0027525324 scopus 로고
    • Ifenprodil discriminates subtypes of the N-methyl-d-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors
    • Williams K. Ifenprodil discriminates subtypes of the N-methyl-d-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors. Mol Pharmacol 44 (1993) 851-859
    • (1993) Mol Pharmacol , vol.44 , pp. 851-859
    • Williams, K.1
  • 68
    • 0032790229 scopus 로고    scopus 로고
    • Subunit- and site-specific pharmacology of the NMDA receptor channel
    • Yamakura T., and Shimoji K. Subunit- and site-specific pharmacology of the NMDA receptor channel. Prog Neurobiol 59 (1999) 279-298
    • (1999) Prog Neurobiol , vol.59 , pp. 279-298
    • Yamakura, T.1    Shimoji, K.2
  • 69
    • 0033529228 scopus 로고    scopus 로고
    • Src, a molecular switch governing gain control of synaptic transmission mediated by N-methyl-d-aspartate receptors
    • Yu X.M., and Salter M.W. Src, a molecular switch governing gain control of synaptic transmission mediated by N-methyl-d-aspartate receptors. Proc Natl Acad Sci U S A 96 (1999) 7697-7704
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 7697-7704
    • Yu, X.M.1    Salter, M.W.2
  • 70
    • 33751117497 scopus 로고    scopus 로고
    • Primary afferent NMDA receptors increase dorsal horn excitation and mediate opiate tolerance in neonatal rats
    • Zeng J., Thomson L.M., Aicher S.A., and Terman G.W. Primary afferent NMDA receptors increase dorsal horn excitation and mediate opiate tolerance in neonatal rats. J Neurosci 26 (2006) 12033-12042
    • (2006) J Neurosci , vol.26 , pp. 12033-12042
    • Zeng, J.1    Thomson, L.M.2    Aicher, S.A.3    Terman, G.W.4
  • 71
    • 38349009068 scopus 로고    scopus 로고
    • Cdk5 regulates the phosphorylation of tyrosine 1472 NR2B and the surface expression of NMDA receptors
    • Zhang S., Edelmann L., Liu J., Crandall J.E., and Morabito M.A. Cdk5 regulates the phosphorylation of tyrosine 1472 NR2B and the surface expression of NMDA receptors. J Neurosci 28 (2008) 415-424
    • (2008) J Neurosci , vol.28 , pp. 415-424
    • Zhang, S.1    Edelmann, L.2    Liu, J.3    Crandall, J.E.4    Morabito, M.A.5
  • 72
    • 61949237557 scopus 로고    scopus 로고
    • Ifenprodil induced antinociception and decreased the expression of NR2B subunits in the dorsal horn after chronic dorsal root ganglia compression in rats
    • Zhang W., Shi C.X., Gu X.P., Ma Z.L., and Zhu W. Ifenprodil induced antinociception and decreased the expression of NR2B subunits in the dorsal horn after chronic dorsal root ganglia compression in rats. Anesth Analg 108 (2009) 1015-1020
    • (2009) Anesth Analg , vol.108 , pp. 1015-1020
    • Zhang, W.1    Shi, C.X.2    Gu, X.P.3    Ma, Z.L.4    Zhu, W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.