Microwave-assisted solvent-free synthesis of bis(dihydropyrimidinone) benzenes and evaluation of their cytotoxic activity: Research article

Chemical Biology and Drug Design

Volumn 75, Issue 4, 2010, Pages 375-380

  Azizian, Javad ^a   Mohammadi, Mohammad K ^a   Firuzi, Omidreza ^b   Mirza, Behrooz ^a   Miri, Ramin ^b  

^a ISLAMIC AZAD UNIVERSITY   (Iran)

^b SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Biginelli reaction; Cytotoxicity; Dihyropyrimidinone; Microwave irradiation; Multicomponent; Terephthalic aldehyde; TMSCl

Indexed keywords

(4,4' (1,4 PHENYLENE)BIS(6 METHYL 2 OXO 1,2,3,4 TETRAHYDROPYRIMIDINE 5,4 DIYL))BIS (PHENYLMETHANONE); 1,1' (4,4' (1,4 PHENYLENE)BIS(2 IMINO 6 METHYL 1,2, 3,4 TETRAHYDROPYRIMIDINE 5,4 DIYL))DIETHANONE; 1,1' (4,4' (1,4 PHENYLENE)BIS(6 METHYL 2 THIOXO 1,2,3,4 TETRAHYDROPYRIMIDINE 5,4 DIYL))DIETHANONE; 4,4' (1,4 PHENYLENE)BIS(5 (THIOPHENE 2 CARBONYL) 6 (TRIFLUOROMETHYL) 3,4 DIHYDROPYRIMIDIN 2(1H)ONE; 4,4' (1,4 PHENYLENE)BIS(5 ACETYL 6 (TRIFLUOROMETHYL) 3,4 DIHYDROPYRIMIDIN 2(1H) ONE); 4,4' (1,4 PHENYLENE)BIS(5 ACETYL 6 METHYL 3,4 DIHYDROPYRIMIDIN 2(1H) ONE; CYTOTOXIC AGENT; DIETHYL 4,4' (1,4 PHENYLENE)BIS(6 METHYL 2 OXO 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXYLATE); SOLVENT; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CELL STRAIN MCF 7; CHEMICAL REACTION; CHEMICAL STRUCTURE; CLINICAL EVALUATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; FEMALE; HELA CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MICROWAVE RADIATION; PRIORITY JOURNAL; RAJI CELL;

ANTINEOPLASTIC AGENTS; BENZENE DERIVATIVES; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; HELA CELLS; HUMANS; MICROWAVES; PYRIMIDINONES; SOLVENTS;

EID: 77449158979     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2009.00937.x     Document Type: Article

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