The ghrelin agonist TZP-101 for management of postoperative ileus after partial colectomy: A randomized, dose-ranging, placebo-controlled clinical trial

Diseases of the Colon and Rectum

Volumn 53, Issue 2, 2010, Pages 126-134

  Popescu, Irinel ^a   Fleshner, Phillip R ^b   Pezzullo, John C ^c   Charlton, Philippa A ^d   Kosutic, Gordana ^d   Senagore, Anthony J ^e  

^a FUNDENI CLINICAL INSTITUTE   (Romania)

^b CEDARS SINAI MEDICAL CENTER   (United States)

^c GEORGETOWN UNIVERSITY   (United States)

^d Tranzyme Inc   (United States)

^e SPECTRUM HEALTH   (United States)

Author keywords

Abdominal surgery; Gastrointestinal; Ghrelin agonist; Ileus; Prokinetic

Indexed keywords

ALVIMOPAN; GHRELIN; GHRELIN AGONIST; GHRELIN RECEPTOR; MU OPIATE RECEPTOR ANTAGONIST; OPIATE; PLACEBO; PROKINETIC AGENT; TZP 101; UNCLASSIFIED DRUG; MACROCYCLIC COMPOUND; TZP-101;

ABDOMINAL SURGERY; ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANEMIA; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CLINICAL TRIAL; COLON RESECTION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DOUBLE BLIND PROCEDURE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; FEMALE; FEVER; FLATULENCE; FOOD INTAKE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; HAZARD RATIO; HUMAN; HYPERGLYCEMIA; HYPERTENSION; HYPOALBUMINEMIA; HYPOPROTEINEMIA; ILEUS; INTESTINE FUNCTION; INTESTINE MOTILITY; KAPLAN MEIER METHOD; LIVER FUNCTION TEST; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NAUSEA; PHASE 2 CLINICAL TRIAL; POSTOPERATIVE COMPLICATION; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; TREATMENT OUTCOME; URINARY TRACT INFECTION; VOMITING; WOUND INFECTION; COMPARATIVE STUDY; DOSE RESPONSE; DRUG POTENTIATION; FOLLOW UP; INTRAVENOUS DRUG ADMINISTRATION; METHODOLOGY; MIDDLE AGED; POSTOPERATIVE CARE; PROCTOCOLECTOMY; RETROSPECTIVE STUDY;

DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; FOLLOW-UP STUDIES; GHRELIN; HUMANS; ILEUS; INFUSIONS, INTRAVENOUS; MACROCYCLIC COMPOUNDS; MALE; MIDDLE AGED; POSTOPERATIVE CARE; PROCTOCOLECTOMY, RESTORATIVE; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 77449137453     PISSN: 00123706     EISSN: 15300358     Source Type: Journal    
DOI: 10.1007/DCR.0b013e3181b54166     Document Type: Article

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