Effect of the ghrelin receptor agonist TZP-101 on colonic transit in a rat model of postoperative ileus

European Journal of Pharmacology

Volumn 604, Issue 1-3, 2009, Pages 132-137

  Fraser, Graeme L ^c   Venkova, Kalina ^a,b   Hoveyda, Hamid R ^c   Thomas, Helmut ^c   Greenwood Van Meerveld, Beverley ^a,b  

^a UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^c Tranzyme Pharma Inc   (Canada)

Author keywords

(Rat); Colonic transit; Fecal pellet output; Ghrelin receptor; Postoperative ileus; TZP 101

Indexed keywords

7 CYCLOPROPYL 13 (4 FLUOROBENZYL) 3 OXA 6,9,12,15 TETRAAZA 4,9,10 TRIMETHYL 4,5,6,7,10,12,13,15,16,17,18 UNDECAHYDRO 1,2 BENZOCYCLOOCTADECENE 8,11,14 TRIONE; DRUG VEHICLE; GASTROINTESTINAL AGENT; GHRELIN RECEPTOR; MORPHINE; TZP 101; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COLON; DRUG MECHANISM; FOOD INTAKE; ILEUS; INTESTINE FUNCTION; INTESTINE TRANSIT TIME; LAPAROTOMY; MALE; NONHUMAN; POSTOPERATIVE CARE; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; RAT; STOMACH EMPTYING;

ABDOMEN; ANIMALS; BODY WEIGHT; COLON; DEFECATION; DISEASE MODELS, ANIMAL; EATING; GASTROINTESTINAL TRANSIT; ILEUS; MACROCYCLIC COMPOUNDS; MALE; MORPHINE; POSTOPERATIVE COMPLICATIONS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GHRELIN; TIME FACTORS;

EID: 58949088281     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.12.011     Document Type: Article

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