Sexual Function in Males After Radiotherapy for Rectal Cancer

International Journal of Radiation Oncology Biology Physics

Volumn 76, Issue 4, 2010, Pages 1012-1017

  Bruheim, Kjersti ^a   Guren, Marianne G ^a   Dahl, Alv A ^b,c   Skovlund, Eva ^d   Balteskard, Lise ^e   Carlsen, Erik ^f   Fosså, Sophie D ^b,c   Tveit, Kjell Magne ^a,c  

^a ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

^c UNIVERSITY OF OSLO   (Norway)

^d UNIVERSITY OF OSLO   (Norway)

^e UNIVERSITY HOSPITAL OF NORTH NORWAY   (Norway)

^f OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

Erectile dysfunction; Late effects; Radiotherapy; Rectal cancer; Sexual function

Indexed keywords

BODY FLUIDS; PATIENT MONITORING; RADIOTHERAPY; SURGERY; SURVEYS;

ERECTILE DYSFUNCTION; LATE EFFECTS; LONG-TERM EFFECTS; METHODS AND MATERIALS; POSTOPERATIVE RADIOTHERAPY; RECTAL CANCER; SERUM TESTOSTERONE; SEXUAL FUNCTIONS;

DISEASES;

FLUOROURACIL; FOLINIC ACID; OXALIPLATIN; SEX HORMONE;

ADULT; AGED; ARTICLE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; HUMAN; MAJOR CLINICAL STUDY; PATIENT SATISFACTION; PRIORITY JOURNAL; QUESTIONNAIRE; RECTUM CANCER; REFLEX; SELF CONCEPT; SEXUAL BEHAVIOR; SEXUAL FUNCTION;

EID: 77449111119     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2009.03.075     Document Type: Article

References (22)

1. Nesbakken A., Nygaard K., Bull-Njaa T., et al. Bladder and sexual dysfunction after mesorectal excision for rectal cancer. Br J Surg 87 (2000) 206-210
2. Maurer C.A. Urinary and sexual function after total mesorectal excision. Recent Results Cancer Res 165 (2005) 196-204
3. Hendren S.K., O'Connor B.I., Liu M., et al. Prevalence of male and female sexual dysfunction is high following surgery for rectal cancer. Ann Surg 242 (2005) 212-223
4. Kim N.K., Aahn T.W., Park J.K., et al. Assessment of sexual and voiding function after total mesorectal excision with pelvic autonomic nerve preservation in males with rectal cancer. Dis Colon Rectum 45 (2002) 1178-1185
5. Pinkawa M., Gagel B., Piroth M.D., et al. Erectile dysfunction after external beam radiotherapy for prostate cancer. Eur Urol 55 (2009) 227-236
6. Mulhall J., Ahmed A., Parker M., et al. The hemodynamics of erectile dysfunction following external beam radiation for prostate cancer. J Sex Med 2 (2005) 432-437
7. Birgisson H., Pahlman L., Gunnarsson U., et al. Late adverse effects of radiation therapy for rectal cancer-a systematic overview. Acta Oncol 46 (2007) 504-516
8. Marijnen C.A., van de Velde C.J.H., Putter H., et al. Impact of short-term preoperative radiotherapy on health-related quality of life and sexual functioning in primary rectal cancer: Report of a multicenter randomized trial. J Clin Oncol 23 (2005) 1847-1858
9. Heriot A.G., Tekkis P.P., Fazio V.W., et al. Adjuvant radiotherapy is associated with increased sexual dysfunction in male patients undergoing resection for rectal cancer: A predictive model. Ann Surg 242 (2005) 502-510
10. Bonnel C., Parc Y.R., Pocard M., et al. Effects of preoperative radiotherapy for primary resectable rectal adenocarcinoma on male sexual and urinary function. Dis Colon Rectum 45 (2002) 934-939
11. Bruheim K., Svartberg J., Carlsen E., et al. Radiotherapy for rectal cancer is associated with reduced serum testosterone and increased FSH and LH. Int J Radiat Oncol Biol Phys 70 (2008) 722-727
12. Rosen R.C., Riley A., Wagner G., et al. The international index of erectile function (IIEF): A multidimensional scale for assessment of erectile dysfunction. Urology 49 (1997) 822-830
13. MAPI Research Trust. Available at: http://www.mapi-trust.org. 2009.
14. Cappelleri J.C., Rosen R.C., Smith M.D., et al. Diagnostic evaluation of the erectile function domain of the International Index of Erectile Function. Urology 54 (1999) 346-351
15. Cappelleri J.C., Siegel R.L., Osterloh I.H., et al. Relationship between patient self-assessment of erectile function and the erectile function domain of the international index of erectile function. Urology 56 (2000) 477-481
16. Tveit K.M., Guldvog I., Hagen S., et al. Randomized controlled trial of postoperative radiotherapy and short-term time-scheduled 5-fluorouracil against surgery alone in the treatment of Dukes B and C rectal cancer. Norwegian Adjuvant Rectal Cancer Project Group. Br J Surg 84 (1997) 1130-1135
17. Braendengen M., Tveit K.M., Berglund A., et al. Randomized Phase III study comparing preoperative radiotherapy with chemoradiotherapy in nonresectable rectal cancer. J Clin Oncol 26 (2008) 3687-3694
18. Kline R.B. Principles and practice of structural equation modelling (2005), Guilford Press, New York
19. van der Wielen G.J., Hoogeman M.S., Dohle G.R., et al. Dose-volume parameters of the corpora cavernosa do not correlate with erectile dysfunction after external beam radiotherapy for prostate cancer: Results from a dose-escalation trial. Int J Radiat Oncol Biol Phys 71 (2008) 795-800
20. Yassin A.A., and Saad F. Testosterone and erectile dysfunction. J Androl 29 (2008) 593-604
21. Morales A., Buvat J., Gooren L.J., et al. Endocrine aspects of sexual dysfunction in men. J Sex Med 1 (2004) 69-81
22. Yoon F.H., Perera F., Fisher B., et al. Alterations in hormone levels after adjuvant chemoradiation in male rectal cancer patients. Int J Radiat Oncol Biol Phys 74 (2009) 1186-1190