Mechanisms of integrin-mediated calcium signaling in MDCK cells: Regulation of adhesion by IP3- and store-independent calcium influx

Molecular Biology of the Cell

Volumn 7, Issue 7, 1996, Pages 1025-1041

  Sjaastad, Michael D ^a   Lewis, Richard S ^a   Nelson, W James ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ARGINYLGLYCYLASPARTIC ACID; CALCIUM CHANNEL; CALCIUM ION; CHONDROITIN SULFATE; HEPARIN; INOSITOL 1,4,5 TRISPHOSPHATE; INTEGRIN; NICKEL; THAPSIGARGIN;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CELL ADHESION; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; EPITHELIUM CELL; EXTRACELLULAR CALCIUM; EXTRACELLULAR MATRIX; FEEDBACK SYSTEM; NONHUMAN; PRIORITY JOURNAL;

EID: 0030035971     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.7.7.1025     Document Type: Article

References (78)

1. Andreason, G.L. (1993). Electroporation as a technique for the transfer of macromolecules into mammmalian cell lines. J. Tissue Cult. Methods 15, 36-62.
2. Arroyo, A.G., Campanero, M.R., Sanchez, M.P., Zapata, J.M., Ursa, M.A., Del, P.M., and Sanchez, M.F. (1994). Induction of tyrosine phosphorylation during ICAM-3 and LFA-1-mediated intercellular adhesion, and its regulation by the CD45 tyrosine phosphatase. J. Cell Biol. 126, 1277-1286.
3. Blake, R.A., Schieven, G.L., and Watson, S.P. (1994). Collagen stimulates tyrosine phosphorylation of phospholipase C-gamma 2 but not phospholipase C-gamma 1 in human platelets. FEBS Lett. 353, 212-216.
4. Boitano, S., Dirksen, E.R., and Sanderson, M.J. (1992). Intercellular propagation of calcium waves mediated by inositol trisphosphate. Science 258, 292-295.
5. Boudreau, N., Sympson, C.J., Werb, Z., and Bissell, M.J. (1995). Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix. Science 267, 891-893.
6. Brooks, P.C., Clark, R.A., and Cheresh, D.A. (1994a). Requirement of vascular integrin alpha v beta 3 for angiogenesis. Science 264, 569-571.
7. Brooks, P.C., Montgomery, A.M., Rosenfeld, M., Reisfeld, R.A., Hu, T., Klier, G., and Cheresh, D.A. (1994b). Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 79, 1157-1164.
8. Buck, C.A., and Horwitz, A.F. (1987). Cell surface receptors for extracellular matrix molecules. Annu. Rev. Cell Biol. 3, 179-205.
9. Burridge, K., Fath, K., Kelly, T., Nuckolls, G., and Turner, C. (1988). Focal adhesions: transmembrane junctions between the extracellular matrix and the cytoskeleton. Annu. Rev. Cell Biol. 4, 487-525.
10. Chenu, C., Colucci, S., Grano, M., Zigrino, P., Barattolo, R., Zambonin, G., Baldini, N., Vergnaud, P., Delmas, P.D., and Zallone, A.Z. (1994). Osteocalcin induces chemotaxis, secretion of matrix proteins, and calcium-mediated intracellular signaling in human osteoclast-like cells. J. Cell Biol. 127, 1149-1158.
11. Clark, E.A., and Brugge, J.S. (1995). Integrins and signal transduction pathways: the road taken. Science 268, 233-239.
12. Damsky, C.H., and Werb, Z. (1992). Signal transduction by integrin receptors for extracellular matrix: cooperative processing of extracellular information. Curr. Opin. Cell Biol. 4, 772-781.
13. De Belder, A.N., and Granath, K. (1973). Preparation and properties of fluorescein-labeled dextrans. Carbohydr. Res. 30, 375.
14. Delles, C., Haller, T., and Dietl, P. (1995). A highly calcium-selective cation current activated by intracellular calcium release in MDCK cells. J. Physiol. 486, 557-569.
15. 2+ entry in MDCK renal epithelial cells. Mol. Pharmacol. 45, 300-305.
16. Di Virgilio, F., Steinberg, T.H., and Silverstein, S.C. (1990). Inhibition of Fura-2 sequestration and secretion with organic anion transport blockers. Cell Calcium 11, 57-62.
17. 2+ influx: how many mechanisms for how many channels? Trends Pharmacol. Sci. 15, 77-83.
18. Felder, C.C., Ma, A.L., Liotta, L.A., and Kohn, E.C. (1991). The antiproliferative and antimetastatic compound L651582 inhibits muscarinic acetylcholine receptor-stimulated calcium influx and arachidonic acid release. J. Pharmacol. Exp. Ther. 257, 967-971.
19. Ghosh, T.K., Eis, P.S., Mullaney, J.M., Ebert, C.L., and Gill, D.L. (1988). Competitive, reversible, and potent antagonism of inositol 1,4,5-trisphosphate-activated calcium release by heparin. J. Biol. Chem. 263, 11075-11079.
20. Ginsberg, M.H., Du, X., and Plow, E.F. (1992). Inside-out integrin signalling. Curr. Opin. Cell Biol. 4, 766-771.
21. 2+ indicators with greatly improved fluorescnce properties. J. Biol. Chem. 260, 3440-3450.
22. Guan, J.L., Trevithick, J.E., and Hynes, R.O. (1991). Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa protein. Cell Regul. 2, 951-964.
23. Hagiwara, S., and Byerly, L. (1981). Calcium Channel. Annu. Rev. Neurosci. 4, 69-125.
24. 3. Science 251, 75-78.
25. Hendey, B., and Maxfield, F.R. (1993). Regulation of neutrophil motility and adhesion by intracellular calcium transients. Blood Cells 19, 143-161; discussion, 161-164.
26. Hill, T.D., Berggren, P.O., and Boynton, A.L. (1987). Heparin inhibits inositol trisphosphate-induced calcium release from permeabilized rat liver cells. Biochem. Biophys. Res. Commun. 149, 897-901.
27. Hoth, M., and Penner, R. (1992). Depletion of intracellular calcium stores activates a calcium current in mast cells. Nature 355, 353-356.
28. Hynes, R.O. (1987). Integrins: a family of cell surface receptors. Cell 48, 549-554.
29. Hynes, R.O. (1992). Integrins: versatility, modulation, and signaling in cell adhesion. Cell 69, 11-25.
30. Ingber, D.E., Prusty, D., Frangioni, J.V., Cragoe, E.J., Lechene, C., and Schwartz, M.A. (1990). Control of intracellular pH and growth by fibronectin in capillary endothelial cells. J. Cell Biol. 110, 1803-1811.
31. Jones, P.L., Schmidhauser, C., and Bissell, M.J. (1993). Regulation of gene expression and cell function by extracellular matrix. Crit. Rev. Eukaryotic Gene Expr. 3, 137-154.
32. Juliano, R.L., and Haskill, S. (1993). Signal transduction from the extracellular matrix. J. Cell Biol. 120, 577-585.
33. Kanner, S.B., Grosmaire, L.S., Ledbetter, J.A., and Damle, N.K. (1993). Beta 2-integrin LFA-1 signaling through phospholipase C-gamma 1 activation. Proc. Natl. Acad. Sci. USA 90, 7099-7103.
34. Klemke, R.L., Yebra, M., Bayna, E.M., and Cheresh, D.A. (1994). Receptor tyrosine kinase signaling required for integrin alpha v beta 5-directed cell motility but not adhesion on vitronectin. J. Cell Biol. 127, 859-866.
35. Kohn, E.C., Alessandro, R., Spoonster, J., Wersto, R.P., and Liotta, L.A. (1995). Angiogenesis: role of calcium-mediated signal transduction. Proc. Natl. Acad. Sci. USA 92, 1307-1311.
36. Kohn, E.C., Felder, C.C., Jacobs, W., Holmes, K.A., Day, A., Freer, R., and Liotta, L.A. (1994). Structure-function analysis of signal and growth inhibition by carboxyamido-triazole, CAI. Cancer Res. 54, 935-942.
37. Kornberg, L., Earp, H.S., Parsons, J.T., Schaller, M., and Juliano, R.L. (1992). Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase. J. Biol. Chem. 267, 23439-23442.
38. Kornberg, L.J., Earp, H.S., Turner, C.E., Prockop, C., and Juliano, R.L. (1991). Signal transduction by integrins: increased protein tyrosine phosphorylation caused by clustering of beta 1 integrins. Proc. Natl. Acad. Sci. USA 88, 8392-8396.
39. Kornberg, L., and Juliano, R.L. (1992). Signal transduction from the extracellular matrix: the integrin-tyrosine kinase connection. Trends Pharmacol. Sci. 13, 93-95.
40. Leavesley, D.I., Schwartz, M.A., Rosenfeld, M., and Cheresh, D.A. (1993). Integrin beta 1- and beta 3-mediated endothelial cell migration is triggered through distinct signaling mechanisms. J. Cell Biol. 121, 163-170.
41. 2+ current in human leukemic T cells. Cell Regul. 2, 99-112.
42. Lückhoff, A., and Clapham, D.E. (1994). Calcium channels activated by depletion of internal calcium stores in A431 cells. Biophys. J. 67, 177-182.
43. McDonald, T.V., Premack, B.A., and Gardner, P. (1993). Flash photolysis of caged inositol 1,4,5-trisphosphate activates plasma membrane calcium current in human T cells. J. Biol. Chem. 268, 3889-3896.
44. McNamee, H.P., Ingber, D.E., and Schwartz, M.A. (1993). Adhesion to fibronectin stimulates inositol lipid synthesis and enhances PDGF-induced inositol lipid breakdown. J. Cell Biol. 121, 673-678.
45. Miyamoto, S., Akiyama, S.K., and Yamada, K.M. (1995). Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function. Science 267, 883-885.
46. 2+ requirements for stimulus-secretion coupling in parietal cell. Am. J. Physiol. 256, C241-C251.
47. Nelson, W.J., and Veshnock, P.J. (1986). Dynamics of membrane-skeleton (fodrin) organization during development of polarity in Madin-Darby canine kidney epithelial cells. J. Cell Biol. 203, 1751-1765.
48. Nelson, W.J., and Veshnock, P.J. (1987). Modulation of fodrin (membrane skeleton) stability by cell-cell contact in Madin-Darby canine kidney epithelial cells. J. Cell Biol. 104, 1527-1537.
49. O'Toole, T.E., Katagiri, Y., Faull, R.J., Peter, K., Tamura, R., Quaranta, V., Loftus, J.C., Shattil, S.J., and Ginsberg, M.H. (1994). Integrin cytoplasmic domains mediate inside-out signal transduction. J. Cell Biol. 224, 1047-1059.
50. Ojakian, G.K., and Schwimmer, R. (1994). Regulation of epithelial cell surface polarity reversal by beta 1 integrins. J. Cell Sci. 107, 561-576.
51. Ozaki, Y., Satoh, K., Yatomi, Y., Miura, S., Fujimura, Y., and Kume, S. (1995). Protein tyrosine phosphorylation in human platelets induced by interaction between glycoprotein Ib and von Willebrand factor. Biochim. Biophys. Acta 1243, 482-488.
52. Paulmichl, M., Pfeilschifter, J., Woll, E., and Lang, F. (1990). Cellular mechanisms of ATP-induced hyperpolarization in renal epitheloid MDCK cells. Mol. Cell. Biol. 20, 57-67.
53. Pavalko, F.M., and Otey, C.A. (1994). Role of adhesion molecule cytoplasmic domains in mediating interactions with the cytoskeleton. Proc. Soc. Exp. Biol. Med. 205, 282-293.
54. Pelletier, A.J., Bodary, S.C., and Levinson, A.D. (1992). Signal transduction by the platelet integrin alpha lib beta 3: induction of calcium oscillations required for protein-tyrosine phosphorylation and ligand-induced spreading of stably transfected cells. Mol. Biol. Cell 3, 989-998.
55. Pierschbacher, M.D., and Ruoslahti, E. (1984a). Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule. Nature 309, 30-33.
56. Pierschbacher, M.D., and Ruoslahti, E. (1984b). Variants of the cell recognition site of fibronectin that retain attachment-promoting activity. Proc. Natl. Acad. Sci. USA 81, 5985-5988.
57. Plopper, G., and Ingber, D.E. (1993). Rapid induction and isolation of focal adhesion complexes. Biochem. Biophys. Res. Commun. 193, 571-578.
58. Putney, J.J., and Bird, G.S. (1993). The inositol phosphate-calcium signaling system in nonexcitable cells. Endocr. Rev. 24, 610-631.
59. Ruoslahti, E., Noble, N.A., Kagami, S., and Border, W.A. (1994). Integrins. Kidney Int. Suppl. S17-S22.
60. Ruoslahti, E., and Pierschbacher, M.D. (1987). New perspectives in cell adhesion: RGD and integrins. Science 238, 491-497.
61. Sastry, S.K., and Horwitz, A.F. (1993). Integrin cytoplasmic domains: mediators of cytoskeletal linkages and extra- and intracellular initiated transmembrane signaling. Curr. Opin. Cell Biol. 5, 819-831.
62. Schaller, M.D., and Parsons, J.T. (1994). Focal adhesion kinase and associated proteins. Curr. Opin. Cell Biol. 6, 705-710.
63. Schoenenberger, C.A., Zuk, A., Zinkl, G.M., Kendall, D., and Matlin, K.S. (1994). Integrin expression and localization in normal MDCK cells and transformed MDCK cells lacking apical polarity. J. Cell Sci. 107, 527-541.
64. Schwartz, M.A. (1993). Spreading of human endothelial cells on fibronectin or vitronectin triggers elevation of intracellular free calcium. J. Cell Biol. 120, 1003-1010.
65. Schwartz, M.A., and Denninghoff, K. (1994). Alpha v integrins mediate the rise in intracellular calcium in endothelial cells on fibronectin even though they play a minor role in adhesion. J. Biol. Chem. 269, 11133-11137.
66. Schwartz, M.A., and Ingber, D.E. (1994). Integrating with integrins. Mol. Biol. Cell 5, 389-393.
67. Shankar, G., Davison, I., Helfrich, M.H., Mason, W.T., and Horton, M.A. (1993). Integrin receptor-mediated mobilisation of intranuclear calcium in rat osteoclasts. J. Cell Sci. 105, 61-68.
68. Shattil, S.J., Haimovich, B., Cunningham, M., Lipfert, L., Parsons, J.T., Ginsberg, M.H., and Brugge, J.S. (1994). Tyrosine phosphorylation of Pp 125FAK in platelets requires coordinated signaling through integrin and agonist receptors. J. Biol. Chem. 269, 14738-14745.
69. 2+ signaling. Proc. Natl. Acad. Sci. USA 91, 8214-8218.
70. 2+ in pancreatic acinar cells via activation of phospholipase C. Biochem. J. 299, 603-611.
71. Streuli, C.H., Schmidhauser, C., Kobrin, M., Bissell, M.J., and Derynck, R. (1993). Extracellular matrix regulates expression of the TGF-beta 1 gene. J. Cell Biol. 120, 253-260.
72. Sultan, C., Plantavid, M., Bachelot, C., Grondin, P., Breton, M., Mauco, G., Levy, T.S., Caen, J.P., and Chap, H. (1991). Involvement of platelet glycoprotein IIb-IIIa (alpha IIb-beta 3 integrin) in thrombin-induced synthesis of phosphatidylinositol 3′,4′-bisphosphate. J. Biol. Chem. 266, 23554-23557.
73. 2+-ATPase. Proc. Natl. Acad. Sci. USA 87, 2466-2470.
74. Vuori, K., and Ruoslahti, E. (1993). Activation of protein kinase C precedes alpha 5 beta 1 integrin-mediated cell spreading on fibronectin. J. Biol. Chem. 268, 21459-21462.
75. Yamada, K.M., and Kennedy, D.W. (1984). Dualistic nature of adhesive protein function: fibronectin and its biologically active peptide fragments can autoinhibit fibronectin function. J. Cell Biol. 99, 29-36.
76. Yurochko, A.D., Liu, D.Y., Eierman, D., and Haskill, S. (1992). Integrins as a primary signal transduction molecule regulating monocyte immediate-early gene induction. Proc. Natl. Acad. Sci. USA 89, 9034-9038.
77. i in rat osteoclasts and mouse-derived osteoclast-like cells. Am. J. Physiol. 266, C376-C381.
78. 2+ stores. Proc. Natl. Acad. Sci. USA 90, 6295-6299.