Elevated albumin in retinas of monkeys with experimental glaucoma

Investigative Ophthalmology and Visual Science

Volumn 51, Issue 2, 2010, Pages 952-959

  Carter Dawson, Louvenia ^a   Zhang, Yujin ^a   Harwerth, Ronald S ^b   Rojas, Ricky ^a   Dash, Pramod ^a   Zhao, Xinping C ^a   WoldeMussie, Elizabeth ^c   Ruiz, Guadalupe ^c   Chuang, Alice ^a   Dubinsky, William P ^d   Redell, John B ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF HOUSTON   (United States)

^c UNIVERSITY OF TEXAS   (United States)

^d UNIVERSITY OF TEXAS DENTAL BRANCH AT HOUSTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; SERUM ALBUMIN; SERUM ALBUMIN PRECURSOR; UNCLASSIFIED DRUG; PROTEIN PRECURSOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLLISIONALLY ACTIVATED DISSOCIATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DISEASE SEVERITY; EYE PROTECTION; FEMALE; GLAUCOMA; IMMUNOHISTOCHEMISTRY; INTRAOCULAR HYPERTENSION; LIQUID CHROMATOGRAPHY; MALE; MOLECULAR WEIGHT; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PURIFICATION; RETINA; RHESUS MONKEY; TANDEM MASS SPECTROMETRY; TWO DIMENSIONAL GEL ELECTROPHORESIS; WESTERN BLOTTING; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; DISEASE MODEL; INTRAOCULAR PRESSURE; MACACA; METABOLISM; MOLECULAR GENETICS; OCULOPLETHYSMOGRAPHY; PATHOPHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEOMICS; RAT; WISTAR RAT;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, WESTERN; DISEASE MODELS, ANIMAL; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; GLAUCOMA; INTRAOCULAR PRESSURE; MACACA MULATTA; MALE; MICROSCOPY, CONFOCAL; MOLECULAR SEQUENCE DATA; PROTEIN PRECURSORS; PROTEOMICS; RATS; RATS, WISTAR; RETINA; SERUM ALBUMIN; TANDEM MASS SPECTROMETRY; TONOMETRY, OCULAR;

EID: 77449090376     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.09-4331     Document Type: Article

References (52)

1. Quigley HA. Number of people with glaucoma worldwide. Br J Ophthalmol. 1996;80:389-393.
2. Challa P. Glaucoma genetics. Int Opthalmol Clin. 2008;48:73-94.
3. Jia LY, Tam PO, Chiang SW, et al. Multiple gene polymorphisms analysis revealed a different profile of genetic polymorphisms of primary open-angle glaucoma in northern Chinese. Mol Vis. 2009; 15:89-98.
4. Caixeta-Umbelino C, de Vasconcellos JP, Costa VP, et al. Lack of association between optineurin gene variants T34T, E50K, M98K, 691-692insAG and R545Q and primary open angle glaucoma in Brazilian patients. Ophthalmic Genet. 2009;30:13-18.
5. Campos-Mollo E, Sánchez-Sánchez F, López-Garrido MP, López-Sánchez E, López-Martínez F, Escribano J. MYOC gene mutations in Spanish patients with autosomal dominant primary open-angle glaucoma: a founder effect in southeast Spain. Mol Vis. 2007;13: 1666-1673.
6. Hayreh SS. Factors influencing blood flow in the optic nerve head. J Glaucoma. 1997;6:412-425.
7. Kerr J, Nelson P, O'Brien C. A comparison of ocular blood flow in untreated primary open-angle glaucoma and ocular hypertension. Am J Ophthalmol. 1998;126:42-51.
8. Quigley HA, Hohman RM, Addicks EM, Massof RW, Green WR. Morphologic changes in the lamina cribrosa correlated with neural loss in open-angle glaucoma. Am J Ophthalmol. 1983;95:673-691.
9. Quigley HA, McKinnon SJ, Zack DJ, et al. Retrograde axonal transport of BDNF in retinal ganglion cells is blocked by acute IOP elevation in rats. Invest Ophthalmol Vis Sci. 2000;41:3460-3466.
10. Pease ME, McKinnon SJ, Quigley HA, Kerrigan-Baumrind LA, Zack DJ. Obstructed axonal transport of BDNF and its receptor TrkB in experimental glaucoma. Invest Ophthalmol Vis Sci. 2000;41:764-774.
11. Romano C, Barrett DA, Li Z, Pestronk A, Wax MB. Anti-rhodopsin antibodies in sera from patients with normal-pressure glaucoma. Invest Ophthalmol Vis Sci. 1995;36:1968-1975.
12. Wax MB, Tezel G, Edward PD. Clinical and ocular histopathological findings in a patient with normal-pressure glaucoma. Arch Ophthalmol. 1998;116:993-1001.
13. Yang J, Patil RV, Yu H, Gordon M, Wax MB. T cell subsets and sIL-2/IL-2 levels in patients with glaucoma. Am J Ophthalmol. 2001;131:421-426.
14. Neufeld AH, Sawada A, Becker B. Inhibition of nitric-oxide synthase 2 by aminoguanidine provides neuroprotection of retinal ganglion cells in a rat model of chronic glaucoma. Proc Natl Acad Sci U S A. 1999;96:9944-9948.
15. Shareef S, Sawada A, Neufeld AH. Isoforms of nitric oxide synthase in the optic nerves of rat eyes with chronic moderately elevated intraocular pressure. Invest Ophthalmol Vis Sci. 1999;40:2884-2891.
16. Liu B, Neufeld AH. Nitric oxide synthase-2 in human optic nerve head astrocytes induced by elevated pressure in vitro. Arch Ophthalmol. 2001;119:240-245.
17. Sullivan RK, Woldemussie E, Macnab L, Ruiz G, Pow DV. Evoked expression of the glutamate transporter GLT-1c in retinal ganglion cells in human glaucoma and in a rat model. Invest Ophthalmol. 2006;47:3853-3859.
18. Vorwerk CK, Gorla MS, Dreyer EB. An experimental basis for implicating excitotoxicity in glaucomatous optic neuropathy. Surv Ophthalmol. 1999;43(suppl 1):S142-150.
19. Seki M, Lipton SA. Targeting excitotoxic/free radical signaling pathways for therapeutic intervention in glaucoma. Prog Brain Res. 2008;173:495-510.
20. Tezel G. Oxidative stress in glaucomatous neurodegeneration: mechanisms and consequences. Prog Retin Eye Res. 2006;25:490-513.
21. Moreno MC, Campanelli J, Sande P, Sanez DA, Keller Sarmiento MI, Rosenstein RE. Retinal oxidative stress induced by high intraocular pressure. Free Radic Biol Med. 2004;37:803-812.
22. Tezel G, Yang G, Cai J. Proteomic identification of oxidatively modified retinal proteins in a chronic pressure-induced rat model of glaucoma. Invest Ophthalmol Vis Sci. 2005;46:3177-3187.
23. Farkas RH, Qian J, Goldberg JL, Quigley HA, Zack DJ. Increased expression of iron-regulating genes in monkey and human glaucoma. Invest Ophthalmol Vis Sci. 2004;45:1410-1417.
24. Quigley HA, Holman RM. Laser energy levels for trabecular meshwork damage in the primate eye. Invest Ophthalmol Vis Sci. 1987;24:1305-1307.
25. Harwerth RS, Smith EL III, DeSantis L. Behavioral perimetry in monkeys. Invest Ophthalmol Vis Sci. 1993;34:31-40.
26. Harwerth RS. Glaucoma Models: Primate. In: Pang IH, Clark A, eds. Animal Models for Retinal Disease. Totowa, NJ: Humana Press; 2009. In press.
27. Harwerth RS, Carter-Dawson L, Smith EL 3rd, Barnes G, Holt WF, Crawford ML. Neural losses correlated with visual losses in clinical perimetry. Invest Ophthalmol Vis Sci. 2004;45:3152-3160.
28. Harwerth RS, Carter-Dawson L, Smith EL 3rd, Crawford ML. Scaling the structure-function relationship for clinical perimetry. Acta Ophthalmol Scand. 2005;83:448-455.
29. Hare W, Wolde Mussie E, Lai R, et al. Efficacy and safety of memantine, an NMDA-type open-channel blocker, for reduction of retinal injury associated with experimental glaucoma in rat and monkey. Surv Ophthalmol. 2001;45(suppl 3):S284-289.
30. Moore CG, Epley D, Milne ST, Morrison JC. Long-term non-invasive measurement of intraocular pressure in the rat eye. Curr Eye Res. 1995;8:711-717.
31. Redell JB, Zhao J, Dash PK. Acutely increased cyclophilin a expression after brain injury: a role in blood-brain barrier function and tissue preservation. J Neurosci Res. 2007;85:1980-1988.
32. Simpson RJ. Proteins and Proteomics: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press; 2003:400-401.
33. Wolde Mussie E, Ruiz G, Wijono M, Wheeler LA. Neuroprotection of retinal ganglion cells by brimonidine in rats with laser-induced chronic ocular hypertension. Invest Ophthalmol Vis Sci. 2001;42: 2849-2855.
34. Woldemussie E, Wijono M, Ruiz G. Müller cell response to laser-induced increase in intraocular pressure in rats. Glia. 2004;47:109-119.
35. Mestriner AC, Haddad A. Serum albumin enters the posterior chamber of the eye permeating the blood-aqueous barrier. Graefes Arch Clin Exp Ophthalmol. 1994;232:242-251.
36. Peters T Jr. All about Albumin: Biochemistry, Genetics, and Medical Applications. San Diego, CA: Academic Press; 1996:432.
37. Tezel G, Luo C, Yang X. Accelerated aging in glaucoma: immunohistochemical assessment of advanced glycation end products in the human retina and optic nerve head. Invest Ophthalmol Vis Sci. 2007;48:1201-1211.
38. Fatokun AA, Stone TW, Smith RA. Oxidative stress in neurodegeneration and available means of protection. Front Biosci. 2008;13: 3288-3311.
39. Belayev L, Saul I, Busto R, et al. Albumin treatment reduces neurological deficit and protects blood-brain barrier integrity after acute intracortical hematoma in the rat. Stroke. 2005;36:326-331.
40. Nimmagadda A, Park HP, Prado R, Ginsberg MD. Albumin therapy improves local vascular dynamics in a rat model of primary microvascular thrombosis: a two-photon laser-scanning microscopy study. Stroke. 2008;9:198-204.
41. Hill MD, Moy CS, Palesch YY, et al. The albumin in acute stroke trial (ALIAS); design and metholodgy. Int J Stroke. 2007;2:214-219.
42. Cain LD, Nie L, Hughes MG, et al. Serum albumin improves recovery from spinal cord injury. J Neurosci Res. 2007;85:1558-1567.
43. Gum ET, Swanson RA, Alano C, et al. Human serum albumin and its N-terminal tetrapeptide (DAHK) oxidant-induced neuronal death. Stroke. 2004;35:590-595.
44. Kiaer C, Thams P. Serum albumin protects from cytokine-induced pancreatic b cell death by a phosphoinositide 3-kinase-dependent mechanism. Endocrine. 2009;35:325-332.
45. Maeda M, Akai F, Nishida S, Yanagihara T. Intracerebral distribution of albumin after transient cerebral ischemia: light and electron microscopic immunocytochemical investigation. Acta Neuropathol. 1992;84:59-66.
46. Løberg EM, Karlsson BR, Torvik A. Neuronal uptake of plasma proteins after transient cerebral ischemia/hypoxia. Immunohistochemical studies on experimental animals and human brains. APMIS. 1993;101:777-783.
47. Sabah JR, Davidson H, McConkey EN, Takemoto LJ. In vivo passage of albumin from the aqueous humor into the lens. Mol Vis. 2004; 10:254-259.
48. Sabah JR, McConkey E, Welti R, Albin K, Takemoto LJ. Role of albumin as a fatty acid carrier for biosynthesis of lens lipids. Exp Eye Res. 2005;80:31-36.
49. Arend O, Remky A, Plange N, Kaup M, Schwartz B. Fluorescein leakage of the optic disc in glaucomatous optic neuropathy. Graefes Arch Clin Exp Ophthalmol. 2005;243:659-664.
50. Tezel G, Wax MB. Hypoxia-inducible factor 1alpha in the glaucomatous retina and optic nerve head. Arch Ophthalmol. 2004;122: 1348-1356.
51. Koto T, Takubo K, Ishida S, et al. Hypoxia disrupts the barrier function of neural blood vessels through changes in the expression of claudin-5 in endothelial cells. Am J Pathol. 2007;170:1389-1397.
52. Mushtaq S, Naqvi ZA, Siddiqui AA, Palmberg C, Shafqat J, Ahmed N. Changes in albumin precursor and heat shock protein 70 expression and their potential role in response to corneal epithelial wound repair. Proteomics. 2007;7:463-468.