Altered Ion Channel Formation by the Parkinson's-Disease-Linked E46K Mutant of α-Synuclein Is Corrected by GM3 but Not by GM1 Gangliosides

Journal of Molecular Biology

Volumn 397, Issue 1, 2010, Pages 202-218

  Di Pasquale, Eric ^a   Fantini, Jacques ^a   Chahinian, Henri ^a   Maresca, Marc ^a   Taïeb, Nadira ^a   Yahi, Nouara ^a  

^a University of Mediterranée   (France)

Author keywords

Langmuir monolayer; Parkinson's disease; planar lipid bilayer; synuclein; amyloid peptide

Indexed keywords

ALANINE; ALPHA SYNUCLEIN; AMYLOID BETA PROTEIN; CATION; GANGLIOSIDE GM1; GANGLIOSIDE GM3; GLYCOSPHINGOLIPID; ION CHANNEL; LYSINE; PHOSPHATIDYLCHOLINE; TYROSINE;

AGING; ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; MOLECULAR MODEL; MUTANT; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INTERACTION; WILD TYPE;

EID: 77449085703     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2010.01.046     Document Type: Article

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