Erythritol is a sweet antioxidant

Nutrition

Volumn 26, Issue 4, 2010, Pages 449-458

  den Hartog, Gertjan J M ^a   Boots, Agnes W ^a   Adam Perrot, Aline ^b   Brouns, Fred ^a   Verkooijen, Inge W C M ^c   Weseler, Antje R ^a   Haenen, Guido R M M ^a   Bast, Aalt ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b Cargill R D Centre Europe   (Belgium)

^c MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Diabetes; Erythritol; Oxidative stress; Rat

Indexed keywords

CARBOHYDRATE; ERYTHRITOL; ERYTHROSE; ERYTHRULOSE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; DRUG STRUCTURE; DRUG TOLERABILITY; DRUG URINE LEVEL; ELECTRON SPIN RESONANCE; ENDOTHELIUM; HEMOLYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; RADICAL REACTION; RAT; STREPTOZOCIN DIABETES; VASCULAR DISEASE;

ANIMALS; ANTIOXIDANTS; BIOLOGICAL MARKERS; BLOOD GLUCOSE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIABETES MELLITUS; DISEASE MODELS, ANIMAL; ELECTRON SPIN RESONANCE SPECTROSCOPY; ENDOTHELIUM, VASCULAR; ERYTHRITOL; FEMALE; FREE RADICAL SCAVENGERS; HYDROXYL RADICAL; MALE; OXIDATIVE STRESS; RATS; RATS, WISTAR; TETROSES;

RATTUS;

EID: 77349122089     PISSN: 08999007     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nut.2009.05.004     Document Type: Article

References (36)

1. Gil-del Valle L., C Milian L d.l., Toledo A., Vilaró N., Tápanes R., and Otero M.A. Altered redox status in patients with diabetes mellitus type I. Pharmacol Res 51 (2005) 375-380
2. Assaloni R., Da Ros R., Quagliaro L., Piconi L., Maier A., Zuodar G., et al. Effects of S21403 (mitiglinide) on postprandial generation of oxidative stress and inflammation in type 2 diabetic patients. Diabetologia 48 (2005) 1919-1924
3. West I.C. Radicals and oxidative stress in diabetes. Diabet Med 17 (2000) 171-180
4. Yoshida K., Hirokawa J., Tagami S., Kawakami Y., Urata Y., and Kondo T. Weakened cellular scavenging activity against oxidative stress in diabetes mellitus: regulation of glutathione synthesis and efflux. Diabetologia 38 (1995) 201-210
5. Goossens J., and Röper H. Erythritol: a new bulk sweetener. Int Food Ingred 1-2 (1994) 27-33
6. Bernt W.O., Borzelleca J.F., Flamm G., and Munro I.C. Erythritol: a review of biological and toxicological studies. Regul Toxicol Pharmacol 24 (1996) S191-S197
7. Munro I.C., Berndt W.O., Borzelleca J.F., Flamm G., Lynch B.S., Kennepohl E., et al. Erythritol: an interpretive summary of biochemical, metabolic, toxicological and clinical data. Food Chem Toxicol 36 (1998) 1139-1174
8. Ching T.L., Haenen G.R., and Bast A. Cimetidine and other H2 receptor antagonists as powerful hydroxyl radical scavengers. Chem Biol Interact 86 (1993) 119-127
9. Li S., Patapoff T.W., Nguyen T.H., and Borchardt R.T. Inhibitory effect of sugars and polyols on the metal-catalyzed oxidation of human relaxin. J Pharm Sci 85 (1996) 868-872
10. Livesey G. Health potential of polyols as sugar replacers, with emphasis on low glycaemic properties. Nutr Res Rev 16 (2003) 163-191
11. Halliwell B., Gutteridge J.M.C., and Aruoma O.I. The deoxyribose method: a simple 'test-tube' assay for determination of rate constants for reactions of hydroxyl radicals. Anal Biochem 165 (1987) 215-219
12. Kirkova M., Atanassova M., and Russanov E. Effects of cimetidine and its metal complexes on nitroblue tetrazolium and ferricytochrome c reduction by superoxide radicals. Gen Pharmacol 33 (1999) 271-276
13. Vosters O., and Nève J. Inhibitory effects of thiol-containing drugs on erythrocyte oxidative damages investigated with an improved assay system. Talanta 57 (2002) 595-600
14. Nascimento R.F., Marques J.C., Lima Neto B.S., De Keukeleire D., and Franco D.W. Qualitative and quantitative high-performance liquid chromatographic analysis of aldehydes in Brazilian sugar cane spirits and other distilled alcoholic beverages. J Chromatogr A 782 (1997) 13-23
15. Hasselbaink D.M., Glatz J.F.C., Luiken J.J.F.P., Roemen T.H.M., and van der Vusse G.J. Ketone bodies disturb fatty acid handling in isolated cardiomyocytes derived from control and diabetic rats. Biochem J 371 (2003) 753-760
16. Baker M.A., Cerniglia G.J., and Zaman A. Microtiter plate assay for the measurement of glutathione and glutathione disulfide in large numbers of biological samples. Anal Biochem 190 (1990) 360-365
17. Vandeputte C., Guizon I., Genestie-Denis I., Vannier B., and Lorenzon G. A microtiter plate assay for total glutathione and glutathione disulfide contents in cultured/isolated cells: performance study of a new miniaturized protocol. Cell Biol Toxicol 10 (1994) 415-421
18. Arts M.J., Haenen G.R., Voss H.P., and Bast A. Antioxidant capacity of reaction products limits the applicability of the Trolox Equivalent Antioxidant Capacity (TEAC) assay. Food Chem Toxicol 42 (2004) 45-49
19. Lepage G., Munoz G., Champagne J., and Roy C.C. Preparative steps necessary for the accurate measurement of malondialdehyde by high-performance liquid chromatography. Anal Biochem 197 (1991) 277-283
20. Buettner G.R. Spin trapping: ESR parameters of spin adducts. Free Radic Biol Med 3 (1987) 259-303
21. van Acker S.A.B.E., van den Berg D.J., Tromp M.N., Griffioen D.H., van Bennekom W.P., van der Vijgh W.J.F., et al. Structural aspects of antioxidant activity of flavonoids. Free Radic Biol Med 20 (1996) 331-342
22. Schuchmann M.N., and Von Sonntag C. Radiation chemistry of carbohydrates. Part 14. Hydroxyl radical induced oxidation of D-glucose in oxygenated aqueous solution. J Chem Soc Perkins Trans II 2 (1977) 1958-1963
23. Cherqaoui A., Takki D., Kokoh K.B., Hahn F., Belgsir E.M., Léger J.-M., et al. Electro-oxidation of meso-erythritol on platinum in acid medium: analysis of the reaction products. J Electroanalyt Chem 464 (1999) 101-109
24. Yokozawa T., Kim H.Y., and Cho E.J. Erythritol attenuates the diabetic oxidative stress through glucose metabolism and lipid peroxidation in streptozotocin-induced diabetic rats. J Agric Food Chem 50 (2002) 5485-5489
25. Gross E.R., LaDisa J.F., Weihrauch D., Olson L.E., Kress T.T., Hettrick D.A., et al. Reactive oxygen species modulate coronary wall shear stress and endothelial function during hyperglycemia. Am J Physiol Heart Circ Physiol 284 (2003) H1552-H1559
26. Widlansky M.E., Gokce N., Keany J.F., and Vita J.A. The clinical implications of endothelial dysfunction. J Am Coll Cardiol 42 (2003) 1149-1160
27. Praticò D. Antioxidants and endothelium protection. Atherosclerosis 181 (2005) 215-224
28. Leighton F., Miranda-Rottmann S., and Urquiaga I. A central role of eNOS in the protective effect of wine against metabolic syndrome. Cell Biochem Funct 24 (2006) 291-298
29. Halcox J.P., Schenke W.H., Zalos G., Mincemoyer R., Prasad A., Waclawiw M.A., et al. Prognostic value of coronary vascular endothelial dysfunction. Circulation 6 (2002) 653-658
30. Dhein S., Kabat A., Olbrich A., Rosen P., Schroder H., and Mohr F.W. Effect of chronic treatment with vitamin E on endothelial dysfunction in a type I in vivo diabetes mellitus model and in vitro. J Pharmacol Exp Ther 305 (2003) 114-122
31. Wang X., and Quinn P.J. Vitamin E and its function in membranes. Prog Lipid Res 38 (1999) 309-336
32. Ceriello A. New insights on oxidative stress and diabetic complications may lead to a "causal" antioxidant therapy. Diabetes Care 26 (2003) 1589-1596
33. Pennathur S., Wagner J.D., Leeuwenburgh C., Litwak K.N., and Heinecke J.W. A hydroxyl radical-like species oxidizes cynomolgus monkey artery wall proteins in early diabetic vascular disease. J Clin Invest 107 (2001) 853-860
34. Goris R.J.A. Treatment of reflex sympathetic dystrophy with hydroxyl radical scavengers. Unfallchirurg 88 (1985) 330-332
35. Matsushima H., Yonemura K., Ohishi K., and Hishida A. The role of oxygen free radicals in cisplatin-induced acute renal failure in rats. J Lab Clin Med 131 (1998) 518-526
36. Meijer E.P., Coolen S.A., Bast A., and Westerterp K.R. Exercise-induced oxidative stress in older adults as measure by antipyrine oxidation. Metabolism 50 (2001) 1484-1488