-
1
-
-
21544447530
-
Characterization of a human monoclonal antibody against Shiga toxin 2 expressed in Chinese hamster ovary cells
-
Akiyoshi, D. E., C. M. Rich, S. O'Sullivan-Murphy, L. Richard, J. Dilo, A. Donohue-Rolfe, A. S. Sheoran, S. Chapman-Bonofiglio, and S. Tzipori. 2005. Characterization of a human monoclonal antibody against Shiga toxin 2 expressed in Chinese hamster ovary cells. Infect. Immun. 73:4054-4061.
-
(2005)
Infect. Immun
, vol.73
, pp. 4054-4061
-
-
Akiyoshi, D.E.1
Rich, C.M.2
O'Sullivan-Murphy, S.3
Richard, L.4
Dilo, J.5
Donohue-Rolfe, A.6
Sheoran, A.S.7
Chapman-Bonofiglio, S.8
Tzipori, S.9
-
2
-
-
39549121093
-
-
Andrew, S. M., and J. A. Titus. 2003. Fragmentation of immunoglobulin G. Curr. Protoc. Cell Biol. 16:16.4.
-
Andrew, S. M., and J. A. Titus. 2003. Fragmentation of immunoglobulin G. Curr. Protoc. Cell Biol. 16:16.4.
-
-
-
-
3
-
-
33748313351
-
Retrograde transport from endosomes to the trans-Golgi network
-
Bonifacino, J. S., and R. Rojas. 2006. Retrograde transport from endosomes to the trans-Golgi network. Nat. Rev. Mol. Cell Biol. 7:568-579.
-
(2006)
Nat. Rev. Mol. Cell Biol
, vol.7
, pp. 568-579
-
-
Bonifacino, J.S.1
Rojas, R.2
-
5
-
-
77349105356
-
-
Edwards, A. C., A. R. Melton-Celsa, K. Arbuthnott, J. R. Stinson, C. K. Schmitt, H. C. Wong, and A. O'Brien. 1998. Vero cell neutralization and mouse protective efficacy of humanized monoclonal antibodies against Escherichia coli toxins Stx1 and Stx2, p. 388-392. In J. B. Kasper and A. D. O'Brien (ed.), Escherichia coli O157:H7 and other Shiga toxin-producing E. coli strains. American Society for Microbiology, Washington, DC.
-
Edwards, A. C., A. R. Melton-Celsa, K. Arbuthnott, J. R. Stinson, C. K. Schmitt, H. C. Wong, and A. O'Brien. 1998. Vero cell neutralization and mouse protective efficacy of humanized monoclonal antibodies against Escherichia coli toxins Stx1 and Stx2, p. 388-392. In J. B. Kasper and A. D. O'Brien (ed.), Escherichia coli O157:H7 and other Shiga toxin-producing E. coli strains. American Society for Microbiology, Washington, DC.
-
-
-
-
6
-
-
34248680659
-
Shiga toxin-producing Escherichia coli: An overview
-
Gyles, C. L. 2007. Shiga toxin-producing Escherichia coli: an overview. J. Anim. Sci. 85:E45-E62.
-
(2007)
J. Anim. Sci
, vol.85
-
-
Gyles, C.L.1
-
7
-
-
4344620978
-
Characterization of a Shiga toxin 1-neutralizing recombinant Fab fragment isolated by phage display system
-
Inoue, K., K. Itoh, H. Nakao, T. Takeda, and T. Suzuki. 2004. Characterization of a Shiga toxin 1-neutralizing recombinant Fab fragment isolated by phage display system. Tohoku J. Exp. Med. 203:295-303.
-
(2004)
Tohoku J. Exp. Med
, vol.203
, pp. 295-303
-
-
Inoue, K.1
Itoh, K.2
Nakao, H.3
Takeda, T.4
Suzuki, T.5
-
8
-
-
0004032583
-
-
5th ed. NIH publication no. 91-3242. U.S. Department of Health and Human Services, Public Health Service, NIH, Bethesda, MD
-
Kabat, E. A., T. T. Wu, H. M. Perry, K. S. Gottesman, and C. Foeller. 1992. Sequences of proteins of immunological interest, 5th ed. NIH publication no. 91-3242. U.S. Department of Health and Human Services, Public Health Service, NIH, Bethesda, MD.
-
(1992)
Sequences of proteins of immunological interest
-
-
Kabat, E.A.1
Wu, T.T.2
Perry, H.M.3
Gottesman, K.S.4
Foeller, C.5
-
9
-
-
24044469996
-
Enterohaemorrhagic Escherichia coli in human medicine
-
Karch, H., P. I. Tarr, and M. Bielaszewska. 2005. Enterohaemorrhagic Escherichia coli in human medicine. Int. J. Med. Microbiol. 295:405-418.
-
(2005)
Int. J. Med. Microbiol
, vol.295
, pp. 405-418
-
-
Karch, H.1
Tarr, P.I.2
Bielaszewska, M.3
-
10
-
-
4143084550
-
Infection by Shiga toxin-producing Escherichia coli: An overview
-
Karmali, M. A. 2004. Infection by Shiga toxin-producing Escherichia coli: an overview. Mol. Biotechnol. 26:117-122.
-
(2004)
Mol. Biotechnol
, vol.26
, pp. 117-122
-
-
Karmali, M.A.1
-
11
-
-
42949178089
-
Intracellular neutralization of Shiga toxin 2 by an A subunit-specific human monoclonal antibody
-
Krautz-Peterson, G., S. Chapman-Bonofiglio, K. Boisvert, H. Feng, I. M. Herman, S. Tzipori, and A. S. Sheoran. 2008. Intracellular neutralization of Shiga toxin 2 by an A subunit-specific human monoclonal antibody. Infect. Immun. 76:1931-1939.
-
(2008)
Infect. Immun
, vol.76
, pp. 1931-1939
-
-
Krautz-Peterson, G.1
Chapman-Bonofiglio, S.2
Boisvert, K.3
Feng, H.4
Herman, I.M.5
Tzipori, S.6
Sheoran, A.S.7
-
12
-
-
57449109700
-
Engineering an anti-Stx2 antibody to control severe infections of EHEC O157:H7
-
Ma, Y., X. Mao, J. Li, H. Li, Y. Feng, H. Chen, P. Luo, J. Gu, S. Yu, H. Zeng, G. Guo, K. Yang, and Q. Zou. 2008. Engineering an anti-Stx2 antibody to control severe infections of EHEC O157:H7. Immunol. Lett. 121:110-115.
-
(2008)
Immunol. Lett
, vol.121
, pp. 110-115
-
-
Ma, Y.1
Mao, X.2
Li, J.3
Li, H.4
Feng, Y.5
Chen, H.6
Luo, P.7
Gu, J.8
Yu, S.9
Zeng, H.10
Guo, G.11
Yang, K.12
Zou, Q.13
-
13
-
-
0036156075
-
Human Stx2-specific monoclonal antibodies prevent systemic complications of Escherichia coli O157:H7 infection
-
Mukherjee, J., K. Chios, D. Fishwild, D. Hudson, S. O'Donnell, S. M. Rich, A. Donohue-Rolfe, and S. Tzipori. 2002. Human Stx2-specific monoclonal antibodies prevent systemic complications of Escherichia coli O157:H7 infection. Infect. Immun. 70:612-619.
-
(2002)
Infect. Immun
, vol.70
, pp. 612-619
-
-
Mukherjee, J.1
Chios, K.2
Fishwild, D.3
Hudson, D.4
O'Donnell, S.5
Rich, S.M.6
Donohue-Rolfe, A.7
Tzipori, S.8
-
14
-
-
0036784674
-
Production and characterization of protective human antibodies against Shiga toxin 1
-
Mukherjee, J., K. Chios, D. Fishwild, D. Hudson, S. O'Donnell, S. M. Rich, A. Donohue-Rolfe, and S. Tzipori. 2002. Production and characterization of protective human antibodies against Shiga toxin 1. Infect. Immun. 70:5896-5899.
-
(2002)
Infect. Immun
, vol.70
, pp. 5896-5899
-
-
Mukherjee, J.1
Chios, K.2
Fishwild, D.3
Hudson, D.4
O'Donnell, S.5
Rich, S.M.6
Donohue-Rolfe, A.7
Tzipori, S.8
-
15
-
-
0034851401
-
Glycan mimicry as a basis for novel anti-infective drugs
-
Mulvey, G., P. I. Kitov, P. Marcato, D. R. Bundle, and G. D. Armstrong. 2001. Glycan mimicry as a basis for novel anti-infective drugs. Biochimie 83:841-847.
-
(2001)
Biochimie
, vol.83
, pp. 841-847
-
-
Mulvey, G.1
Kitov, P.I.2
Marcato, P.3
Bundle, D.R.4
Armstrong, G.D.5
-
16
-
-
34250803180
-
Neutralizing activity of polyvalent Gb3, Gb2 and galacto-trehalose models against Shiga toxins
-
Neri, P., S. I. Nagano, S. Yokoyama, H. Dohi, K. Kobayashi, T. Miura, T. Inazu, T. Sugiyama, Y. Nishida, and H. Mori. 2007. Neutralizing activity of polyvalent Gb3, Gb2 and galacto-trehalose models against Shiga toxins. Microbiol. Immunol. 51:581-592.
-
(2007)
Microbiol. Immunol
, vol.51
, pp. 581-592
-
-
Neri, P.1
Nagano, S.I.2
Yokoyama, S.3
Dohi, H.4
Kobayashi, K.5
Miura, T.6
Inazu, T.7
Sugiyama, T.8
Nishida, Y.9
Mori, H.10
-
17
-
-
20444390944
-
Identification of the optimal structure required for a Shiga toxin neutralizer with oriented carbohydrates to function in the circulation
-
Nishikawa, K., K. Matsuoka, M. Watanabe, K. Igai, K. Hino, K. Hatano, A. Yamada, N. Abe, D. Terunuma, H. Kuzuhara, and Y. Natori. 2005. Identification of the optimal structure required for a Shiga toxin neutralizer with oriented carbohydrates to function in the circulation. J. Infect. Dis. 191:2097-2105.
-
(2005)
J. Infect. Dis
, vol.191
, pp. 2097-2105
-
-
Nishikawa, K.1
Matsuoka, K.2
Watanabe, M.3
Igai, K.4
Hino, K.5
Hatano, K.6
Yamada, A.7
Abe, N.8
Terunuma, D.9
Kuzuhara, H.10
Natori, Y.11
-
18
-
-
0023237938
-
Shiga and Shiga-like toxins
-
O'Brien, A. D., and R. K. Holmes. 1987. Shiga and Shiga-like toxins. Microbiol. Rev. 51:206-220.
-
(1987)
Microbiol. Rev
, vol.51
, pp. 206-220
-
-
O'Brien, A.D.1
Holmes, R.K.2
-
19
-
-
33845315574
-
Shiga toxin "goes retro" in human primary kidney cells
-
Paton, J. C., and A. W. Paton. 2006. Shiga toxin "goes retro" in human primary kidney cells. Kidney Int. 70:2049-2051.
-
(2006)
Kidney Int
, vol.70
, pp. 2049-2051
-
-
Paton, J.C.1
Paton, A.W.2
-
20
-
-
0031691782
-
Production and characterization of a set of mouse-human chimeric immunoglobulin G (IgG) subclass and IgA monoclonal antibodies with identical variable regions specific for Pseudomonas aeruginosa serogroup O6 lipopolysaccharide
-
Preston, M. J., A. A. Gerceker, M. E. Reff, and G. B. Pier. 1998. Production and characterization of a set of mouse-human chimeric immunoglobulin G (IgG) subclass and IgA monoclonal antibodies with identical variable regions specific for Pseudomonas aeruginosa serogroup O6 lipopolysaccharide. Infect. Immun. 66:4137-4142.
-
(1998)
Infect. Immun
, vol.66
, pp. 4137-4142
-
-
Preston, M.J.1
Gerceker, A.A.2
Reff, M.E.3
Pier, G.B.4
-
21
-
-
34548490308
-
Identification and characterization of small molecules that inhibit intracellular toxin transport
-
Saenz, J. B., T. A. Doggett, and D. B. Haslam. 2007. Identification and characterization of small molecules that inhibit intracellular toxin transport. Infect. Immun. 75:4552-4561.
-
(2007)
Infect. Immun
, vol.75
, pp. 4552-4561
-
-
Saenz, J.B.1
Doggett, T.A.2
Haslam, D.B.3
-
22
-
-
51549116628
-
Treatment and outcome of Shiga-toxin-associated hemolytic uremic syndrome (HUS)
-
Scheiring, J., S. P. Andreoli, and L. B. Zimmerhackl. 2008. Treatment and outcome of Shiga-toxin-associated hemolytic uremic syndrome (HUS). Pediatr. Nephrol. 23:1749-1760.
-
(2008)
Pediatr. Nephrol
, vol.23
, pp. 1749-1760
-
-
Scheiring, J.1
Andreoli, S.P.2
Zimmerhackl, L.B.3
-
23
-
-
36549081013
-
Pathogenesis and treatment of Shiga toxin-producing Escherichia coli infections
-
Serna, A., IV, and E. C. Boedeker. 2008. Pathogenesis and treatment of Shiga toxin-producing Escherichia coli infections. Curr. Opin. Gastroenterol. 24:38-47.
-
(2008)
Curr. Opin. Gastroenterol
, vol.24
, pp. 38-47
-
-
Serna, A.I.1
Boedeker, E.C.2
-
24
-
-
0038444124
-
Stx2-specific human monoclonal antibodies protect mice against lethal infection with Escherichia coli expressing Stx2 variants
-
Sheoran, A. S., S. Chapman, P. Singh, A. Donohue-Rolfe, and S. Tzipori. 2003. Stx2-specific human monoclonal antibodies protect mice against lethal infection with Escherichia coli expressing Stx2 variants. Infect. Immun. 71:3125-3130.
-
(2003)
Infect. Immun
, vol.71
, pp. 3125-3130
-
-
Sheoran, A.S.1
Chapman, S.2
Singh, P.3
Donohue-Rolfe, A.4
Tzipori, S.5
-
25
-
-
23344444656
-
Human antibody against Shiga toxin 2 administered to piglets after the onset of diarrhea due to Escherichia coli O157:H7 prevents fatal systemic complications
-
Sheoran, A. S., S. Chapman-Bonofiglio, B. R. Harvey, J. Mukherjee, G. Georgiou, A. Donohue-Rolfe, and S. Tzipori. 2005. Human antibody against Shiga toxin 2 administered to piglets after the onset of diarrhea due to Escherichia coli O157:H7 prevents fatal systemic complications. Infect. Immun. 73:4607-4613.
-
(2005)
Infect. Immun
, vol.73
, pp. 4607-4613
-
-
Sheoran, A.S.1
Chapman-Bonofiglio, S.2
Harvey, B.R.3
Mukherjee, J.4
Georgiou, G.5
Donohue-Rolfe, A.6
Tzipori, S.7
-
26
-
-
17144365102
-
Hemolytic uremic syndrome; pathogenesis, treatment, and outcome
-
Siegler, R., and R. Oakes. 2005. Hemolytic uremic syndrome; pathogenesis, treatment, and outcome. Curr. Opin. Pediatr. 17:200-204.
-
(2005)
Curr. Opin. Pediatr
, vol.17
, pp. 200-204
-
-
Siegler, R.1
Oakes, R.2
-
27
-
-
67650096429
-
Monoclonal antibody 11E10 which neutralizes Shiga toxin type 2 (Stx2), recognizes three regions on the Stx2 A subunit, blocks the enzymatic action of the toxin in vitro, and alters the overall cellular distribution of the toxin
-
Smith, M. J., A. R. Melton-Celsa, J. F. Sinclair, H. M. Carvalho, C. M. Robinson, and A. D. O'Brien. 2009. Monoclonal antibody 11E10 which neutralizes Shiga toxin type 2 (Stx2), recognizes three regions on the Stx2 A subunit, blocks the enzymatic action of the toxin in vitro, and alters the overall cellular distribution of the toxin. Infect. Immun. 77:2730-2740.
-
(2009)
Infect. Immun
, vol.77
, pp. 2730-2740
-
-
Smith, M.J.1
Melton-Celsa, A.R.2
Sinclair, J.F.3
Carvalho, H.M.4
Robinson, C.M.5
O'Brien, A.D.6
-
28
-
-
15244348050
-
Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome
-
Tarr, P. I., C. A. Gordon, and W. L. Chandler. 2005. Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome. Lancet 365:1073-1086.
-
(2005)
Lancet
, vol.365
, pp. 1073-1086
-
-
Tarr, P.I.1
Gordon, C.A.2
Chandler, W.L.3
-
29
-
-
37849003390
-
Protection of mice from Shiga toxin-2 toxemia by mucosal vaccine of Shiga toxin 2B-His with Escherichia coli enterotoxin
-
Tsuji, T., T. Shimizu, K. Sasaki, Y. Shimizu, K. Tsukamoto, H. Arimitsu, S. Ochi, S. Sugiyama, K. Taniguchi, P. Neri, and H. Mori. 2008. Protection of mice from Shiga toxin-2 toxemia by mucosal vaccine of Shiga toxin 2B-His with Escherichia coli enterotoxin. Vaccine 26:469-476.
-
(2008)
Vaccine
, vol.26
, pp. 469-476
-
-
Tsuji, T.1
Shimizu, T.2
Sasaki, K.3
Shimizu, Y.4
Tsukamoto, K.5
Arimitsu, H.6
Ochi, S.7
Sugiyama, S.8
Taniguchi, K.9
Neri, P.10
Mori, H.11
-
30
-
-
41549158210
-
A nasal vaccine comprising B-subunit derivative of Shiga toxin 2 for cross-protection against Shiga toxin types 1 and 2
-
Tsuji, T., T. Shimizu, K. Sasaki, K. Tsukamoto, H. Arimitsu, S. Ochi, K. Taniguchi, M. Noda, P. Neri, and H. Mori. 2008. A nasal vaccine comprising B-subunit derivative of Shiga toxin 2 for cross-protection against Shiga toxin types 1 and 2. Vaccine 26:2092-2099.
-
(2008)
Vaccine
, vol.26
, pp. 2092-2099
-
-
Tsuji, T.1
Shimizu, T.2
Sasaki, K.3
Tsukamoto, K.4
Arimitsu, H.5
Ochi, S.6
Taniguchi, K.7
Noda, M.8
Neri, P.9
Mori, H.10
-
31
-
-
5644227317
-
Antibody therapy in the management of Shiga toxin-induced hemolytic uremic syndrome
-
table of contents
-
Tzipori, S., A. Sheoran, D. Akiyoshi, A. Donohue-Rolfe, and H. Trachtman. 2004. Antibody therapy in the management of Shiga toxin-induced hemolytic uremic syndrome. Clin. Microbiol. Rev. 17:926-941, table of contents.
-
(2004)
Clin. Microbiol. Rev
, vol.17
, pp. 926-941
-
-
Tzipori, S.1
Sheoran, A.2
Akiyoshi, D.3
Donohue-Rolfe, A.4
Trachtman, H.5
-
32
-
-
0001127374
-
Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity
-
Urlaub, G., and L. A. Chasin. 1980. Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity. Proc. Natl. Acad. Sci. U. S. A. 77:4216-4220.
-
(1980)
Proc. Natl. Acad. Sci. U. S. A
, vol.77
, pp. 4216-4220
-
-
Urlaub, G.1
Chasin, L.A.2
-
33
-
-
0023029414
-
Effect of gamma rays at the dihydrofolate reductase locus: Deletions and inversions
-
Urlaub, G., P. J. Mitchell, E. Kas, L. A. Chasin, V. L. Funanage, T. T. Myoda, and J. Hamlin. 1986. Effect of gamma rays at the dihydrofolate reductase locus: deletions and inversions. Somat. Cell Mol. Genet. 12:555-566.
-
(1986)
Somat. Cell Mol. Genet
, vol.12
, pp. 555-566
-
-
Urlaub, G.1
Mitchell, P.J.2
Kas, E.3
Chasin, L.A.4
Funanage, V.L.5
Myoda, T.T.6
Hamlin, J.7
-
34
-
-
0034729744
-
The risk of the hemolytic-uremic syndrome after antibiotic treatment of Escherichia coli O157:H7 infections
-
Wong, C. S., S. Jelacic, R. L. Habeeb, S. L. Watkins, and P. I. Tarr. 2000. The risk of the hemolytic-uremic syndrome after antibiotic treatment of Escherichia coli O157:H7 infections. N. Engl. J. Med. 342:1930-1936.
-
(2000)
N. Engl. J. Med
, vol.342
, pp. 1930-1936
-
-
Wong, C.S.1
Jelacic, S.2
Habeeb, R.L.3
Watkins, S.L.4
Tarr, P.I.5
-
35
-
-
0035884459
-
Efficacy of postinfection treatment with anti-Shiga toxin (Stx) 2 humanized monoclonal antibody TMA-15 in mice lethally challenged with Stx-producing Escherichia coli
-
Yamagami, S., M. Motoki, T. Kimura, H. Izumi, T. Takeda, Y. Katsuura, and Y. Matsumoto. 2001. Efficacy of postinfection treatment with anti-Shiga toxin (Stx) 2 humanized monoclonal antibody TMA-15 in mice lethally challenged with Stx-producing Escherichia coli. J. Infect. Dis. 184:738-742.
-
(2001)
J. Infect. Dis
, vol.184
, pp. 738-742
-
-
Yamagami, S.1
Motoki, M.2
Kimura, T.3
Izumi, H.4
Takeda, T.5
Katsuura, Y.6
Matsumoto, Y.7
|