메뉴 건너뛰기




Volumn 13, Issue 3, 2010, Pages 166-168

Why realistic test scenarios in translational genomics research remain hypothetical

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; ENVIRONMENTAL FACTOR; GENE FREQUENCY; GENE LOCUS; GENETIC ANALYSIS; GENETIC MARKER; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOMICS; GENOTYPE; HUMAN; PRIORITY JOURNAL; RESEARCH;

EID: 77349109788     PISSN: 16624246     EISSN: None     Source Type: Journal    
DOI: 10.1159/000236062     Document Type: Article
Times cited : (3)

References (18)
  • 1
    • 43049146524 scopus 로고    scopus 로고
    • A HapMap harvest of insights into the genetics of common disease
    • Manolio TA, Brooks LD, Collins FS: A HapMap harvest of insights into the genetics of common disease. J Clin Invest 2008; 118: 1590-1605.
    • (2008) J Clin Invest , vol.118 , pp. 1590-1605
    • Manolio, T.A.1    Brooks, L.D.2    Collins, F.S.3
  • 2
    • 25144433506 scopus 로고    scopus 로고
    • Realizing the promise of genomics in biomedical research
    • Guttmacher AE, Collins FS: Realizing the promise of genomics in biomedical research. JAMA 2005; 294: 1399-1402.
    • (2005) JAMA , vol.294 , pp. 1399-1402
    • Guttmacher, A.E.1    Collins, F.S.2
  • 4
    • 41149120561 scopus 로고    scopus 로고
    • A critical appraisal of the scientific basis of commercial genomic profiles used to assess health risks and personalize health interventions
    • Janssens ACJW, Gwinn M, Bradley LA, Oostra BA, Van Duijn CM, Khoury MJ: A critical appraisal of the scientific basis of commercial genomic profiles used to assess health risks and personalize health interventions. Am J Hum Genet 2008; 82: 593-599.
    • (2008) Am J Hum Genet , vol.82 , pp. 593-599
    • Janssens, A.C.J.W.1    Gwinn, M.2    Bradley, L.A.3    Oostra, B.A.4    Van Duijn, C.M.5    Khoury, M.J.6
  • 5
    • 38549085235 scopus 로고    scopus 로고
    • Research ethics and the challenge of whole-genome sequencing
    • McGuire AL, Caulfield T, Cho MK: Research ethics and the challenge of whole-genome sequencing. Nat Rev Genet 2008; 9: 152-156.
    • (2008) Nat Rev Genet , vol.9 , pp. 152-156
    • McGuire, A.L.1    Caulfield, T.2    Cho, M.K.3
  • 6
    • 33750388916 scopus 로고    scopus 로고
    • The emergence of an ethical duty to disclose genetic research results: International perspectives
    • Knoppers BM, Joly Y, Simard J, Durocher F: The emergence of an ethical duty to disclose genetic research results: international perspectives. Eur J Hum Genet 2006; 14: 1170-1178.
    • (2006) Eur J Hum Genet , vol.14 , pp. 1170-1178
    • Knoppers, B.M.1    Joly, Y.2    Simard, J.3    Durocher, F.4
  • 7
    • 77349095299 scopus 로고    scopus 로고
    • Considerations for designing a prototype genetic test to use in translational research
    • DOI: 10.1159/000236061
    • Wade CH, McBride CM, Kardia SLR, Brody LC: Considerations for designing a prototype genetic test to use in translational research. Public Health Genomics DOI: 10.1159/000236061.
    • Public Health Genomics
    • Wade, C.H.1    McBride, C.M.2    Kardia, S.L.R.3    Brody, L.C.4
  • 9
    • 36248973674 scopus 로고    scopus 로고
    • Assessing hypothetical scenario methodology in genetic susceptibility testing analog studies: A quantitative review
    • Persky S, Kaphingst KA, Condit CM, Mc-Bride CM: Assessing hypothetical scenario methodology in genetic susceptibility testing analog studies: a quantitative review. Genet Med 2007; 9: 727-738.
    • (2007) Genet Med , vol.9 , pp. 727-738
    • Persky, S.1    Kaphingst, K.A.2    Condit, C.M.3    Mc-Bride, C.M.4
  • 10
    • 17744373679 scopus 로고    scopus 로고
    • Do we need genomic research for the prevention of common diseases with environmental causes?
    • Khoury MJ, Davis R, Gwinn M, Lindegren ML, Yoon P: Do we need genomic research for the prevention of common diseases with environmental causes? Am J Epidemiol 2005; 161: 799-805.
    • (2005) Am J Epidemiol , vol.161 , pp. 799-805
    • Khoury, M.J.1    Davis, R.2    Gwinn, M.3    Lindegren, M.L.4    Yoon, P.5
  • 11
    • 57649243614 scopus 로고    scopus 로고
    • Genomebased prediction of common diseases: Advances and prospects
    • Janssens ACJW, Van Duijn CM: Genomebased prediction of common diseases: advances and prospects. Hum Mol Genet 2008; 17:R166-R173.
    • (2008) Hum Mol Genet , vol.17
    • Janssens, A.C.J.W.1    Van Duijn, C.M.2
  • 13
    • 56349096931 scopus 로고    scopus 로고
    • Lango H; UK Type 2 Diabetes Genetics Consortium, Palmer CN, Morris AD, Zeggini E, Hattersley AT, McCarthy MI, Frayling TM, Weedon MN: Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk. Diabetes 2008; 57: 3129-3135.
    • Lango H; UK Type 2 Diabetes Genetics Consortium, Palmer CN, Morris AD, Zeggini E, Hattersley AT, McCarthy MI, Frayling TM, Weedon MN: Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk. Diabetes 2008; 57: 3129-3135.
  • 16
    • 40949112321 scopus 로고    scopus 로고
    • Delivery of genomic medicine for common chronic adult diseases: A systematic review
    • Scheuner MT, Sieverding P, Shekelle PG: Delivery of genomic medicine for common chronic adult diseases: a systematic review. JAMA 2008; 299: 1320-1334.
    • (2008) JAMA , vol.299 , pp. 1320-1334
    • Scheuner, M.T.1    Sieverding, P.2    Shekelle, P.G.3
  • 17
    • 57649210710 scopus 로고    scopus 로고
    • Is the time right for translation research in genomics?
    • Janssens AC: Is the time right for translation research in genomics? Eur J Epidemiol 2008; 23: 707-710.
    • (2008) Eur J Epidemiol , vol.23 , pp. 707-710
    • Janssens, A.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.