An overview on the small heat shock proteins

African Journal of Biotechnology

Volumn 9, Issue 7, 2010, Pages 927-939

  Mahmood, Tariq ^a   Safdar, Waseem ^a   Abbasi, Bilal Haider ^a   Naqvi, S M Saqlan ^b  

^a QUAID I AZAM UNIVERSITY   (Pakistan)

^b PMAS ARID AGRICULTURE UNIVERSITY   (Pakistan)

Author keywords

Function; Localization; Molecular evolution; Small heat shock proteins; Structural dynamics

Indexed keywords

CHAPERONE; HEAT SHOCK PROTEIN 100; HEAT SHOCK PROTEIN 60; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; OXYGEN; SMALL HEAT SHOCK PROTEIN; UBIQUITIN;

BIRD; CELL MEMBRANE; CELL NUCLEUS; CELL STRESS; CHLOROPLAST; CYTOSKELETON; DROSOPHILA; EMBRYO DEVELOPMENT; ENDOPLASMIC RETICULUM; ENVIRONMENTAL STRESS; EUKARYOTE; GENE EXPRESSION; GERMINATION; HIGH TEMPERATURE; MAMMAL; MITOCHONDRION; MOLECULAR EVOLUTION; MOLECULAR WEIGHT; NONHUMAN; PH; PLASTID; POLLEN DEVELOPMENT; PROKARYOTE; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN DENATURATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; REGULON; RESPIRATORY CHAIN; REVIEW; WATER DEPRIVATION; YEAST CELL;

ANIMALIA; AVES; EUKARYOTA; MAMMALIA; PROKARYOTA;

EID: 77249179803     PISSN: None     EISSN: 16845315     Source Type: Journal    
DOI: 10.5897/ajb09.006     Document Type: Review

References (96)

1. 2+ Binding, Redox Silencing, and Cytoprotective effects of the Small Heat Shock Proteins aA- and aB-Crystallin. J. Mol. Biol. 382(3): 812-824.
2. Ahn YJ, Claussen K, Zimmerman JL (2004). Genotypic differences in the heat shock response and thermotolerance in four potato cultivars. Plant Sci. 166: 901-911.
3. Almoguera C, Dapena PP, Jordano J (1998). Dual regulation of a heat shock promoter during embryogenesis: stage-dependent role of heat shock elements. Plant J. 13(4): 437-446.
4. Antonova G, Lichtenbeld H, Xia T, Chatterjee A, Dimitropoulou C, Catravas JD (2007). Functional significance of hsp90 complexes with NOS and sGC in endothelial cells. Clin. Hemorheol. Microcirs. 37(1-2): 19-35.
5. Atungulu E, Tanaka H, Fujita K, Yamamoto KI, Sakata M, Sato E, Hara M, Yamashita T, Suzuki K (2006). A double chaperone function of the sHSPs genes against heat-based environmental adversity in the soildwelling leaf beetles. J. Ins. Biotechnol Sericol. 75(1): 15-22.
6. Barcala M, Garcia A, Cubas P, Almoguera C, Jordano J, Fenoll C, Escobar C (2008). Distinct heat-shock element arrangements that mediate the heat shock, but not the late-embryogenesis induction of small heat-shock proteins, correlate with promoter activation in rootknot nematode feeding cells. Plant Mol. Biol. 66: 151-164.
7. Basha E, Friedrich KL, Vierling E (2006). The N-terminal arm of small heat shock proteins is important for both chaperone activity and substrate specificity. J. Biol. Chem. 281(52): 39943-39952.
8. Benjamin IJ, McMillan DR (1998). Stress (heat shock) proteins: molecular chaperones in cardiovascular biology and disease. Circ. Res. 83(2): 117-132.
9. Borges JC, Ramos CH (2005). Protein folding assisted by chaperones. Protein Peptide lett. 12(3): 257-261.
10. Carranco R, Almoguera C, Jordano J (1999). An imperfect heat shock element and different upstream sequences are required for the seedspecific expression of a small heat shock protein gene. Plant Physiol. 121:723-730.
11. Carver JA, Rekas A, Thorn DC, Wilson MR (2003). Small Heat-shock Proteins and Clusterin: Intra-and Extracellular Molecular Chaperones with a Common Mechanism of Action and Function. IUBMB Life. 55(12): 661-668.
12. Chang PFL, Huang CI, Chang FC, Tseng TS, Lin WC, Lin CY (2001). Isolation and characterization of the third gene encoding a 16.9-kDa class I low-molecular-mass heat shock protein, Oshsp16.9C, in rice. Bot. Bull. Acad. Sinica. 42: 85-92.
13. Chang PFL, Huang WK, Jinn TL, Wang CW, Lin PL, Chang HM (2005). The class II small heat shock gene of rice (Oryza sativa L.), OsHSP 18.0-CII, is induced by heat stress, mechanical injury, and also confers tolerance to heat and UV stresses when overexpressing in Escherichia coli. Am. Soc. Plant Biol. Abst. #178. (http://abstract. aspb.org/pb2005/pubic/p38/8248.html).
14. Chang PFL, Jinn TL, Huang WK, Chen Y, Chang HM, Wang CW (2007). Induction of a cDNA clone from rice encoding a class II small heat shock protein by heat stress, mechanical injury, and salicylic acid. Plant Sci. 172: 64-75.
15. Ciocca DR, Calderwood SK (2005). Heat shock proteins in cancers: diagnostic, prognostic, predictive, and treatment implications. Cell Stress Chap. 10: 86-103.
16. Coca MA, Almoguera C, Thomas TL, Jordano J (1996). Differential regulation of small heat-shock genes in plants: Analysis of a waterstress-inducible and developmentally activated sunflower promoter. Plant Mol. Biol. 31(4): 863-876.
17. Coca MA, Almoguera C, Jordano J (1994). Expression of sunflower lowmolecular-weight heat-shock proteins during embryogenesis and persistence after germination: localization and possible functional implications. Plant Mol. Biol. 25: 479-492.
18. Dafny-Yelin M, Tzfira T, Vainstein A, Adam Z (2008). Non-redundant functions of sHSP-CIs in acquired thermotolerance and their role in early seed development in Arabidopsis. Plant Mol. Biol. 67: 363-373.
19. Dell'Aquila A (2000). Effect of combined salt and heat treatments on germination and heat-shock protein synthesis in lentil seeds. Biol. Plantarum. 43(4): 591-594.
20. De Rocher AE, Vierling E (1994). Developmental control of small heat shock protein expression during pea seed maturation. Plant J. 5: 93-102.
21. Dillmann WH (1999). Small heat shock proteins and protection against injury. Ann. NY. Acad. Sci. 874: 66-68.
22. Doerwald L, Onnekink C, Van Genesen ST, De Jong WW, Lubsen NH (2003). Translational Thermotolerance Provided by Small Heat Shock Proteins Is Limited to Cap-dependent Initiation and Inhibited by 2-Aminopurine. J. Biol. Chem. 278: 49743-49750.
23. Doerwald L, Rheede TV, Dirks RP, Madsen O, Rexwinkel R, Van Genesen ST, Martens GJ, De Jong WW, Lubsen NH (2004). Sequence and functional conservation of the intergenic region between the head-to-head genes encoding the small heat shock proteins aB-crystallin and HspB2 in the mammalian lineage. J. Mol. Evol. 59(5): 674-686.
24. Doran P, Gannon J, Connell OK, Ohlendieck K (2007). Aging skeletal muscle shows a drastic increase in the small heat shock proteins aBcrystallin/ HspB5 and cvHsp/HspB7. Eur. J. Cell Biol. 86(10): 629-640.
25. Downs CA, Coleman JS, Heckathorn SA (1999a). The chloroplast 22-kD heat-shock protein: a lumenal protein that associates with the oxygen-evolving complex and protects Photosystem II during heat stress. J. Plant Physiol. 155: 477-478.
26. Downs CA, Ryan SL, Heckathorn SA (1999b). The chloroplast small heat-shock protein: evidence for a general role in protecting photosystem II against oxidative stress and photoinhibition. J. Plant Physiol. 155: 488-496.
27. Downs CA, Jones LR, Heckathorn SA (1999c). Evidence for a novel set of small heat-shock proteins that associates with the mitochondria of murine PC12 cells and protects NADH:ubiquinone oxidoreductase from heat and oxidative stress. Arch. Biochem. Biophys. 365: 344-350.
28. Escobar C, Barcala M, Portillo M, Almoguera C, Jordano J, Fenoll C (2003). Induction of the Hahsp17.7G4 Promoter by Root-Knot Nematodes: Involvement of Heat-Shock Elements in Promoter Activity in Giant Cells. Mol. Plant Micro. In. 16(12): 1062-1068.
29. Fan GC, Ren X, Qian J, Yuan Q, Nicolaou P, Wang Y, Jones WK, Chu G, Kranias EG (2005). Novel cardioprotective role of a small heatshock protein, Hsp20, against ischemia/reperfusion injury. Circulation, 111(14): 1792-1799.
30. Feder ME, Hofmann GE (1999). Heat-Shock Proteins, Molecular Chaperones, And The Stress Response: Evolutionary and Ecological Physiology. Ann. Rev. Physiol. 61: 243-282.
31. Franck E, Madsen O, Van Rheede T, Ricard G, Huynen MA, De Jong WW (2004). Evolutionary diversity of vertebrate small heat shock proteins. J. Mol. Evol. 59(6): 792-805.
32. Fu X, Jiao W, Chang Z (2006). Phylogenetic and biochemical studies reveal a potential evolutionary origin of small heat shock proteins of animals from bacterial class A. J. Mol. Evol. 62: 257-266.
33. Ganea E (2001). Chaperone-like activity of a-crystallin and other small heat shock proteins. Curr. Protein Pept. Sci. 2: 205-225.
34. Guan JC, Chang FC, Tseng TS, Chang PFL, Yeh KW, Chen YM, Lin CY (1998). Structure of rice genes encoding three class-I lowmolecular-mass heat-shock proteins (accession Nos. U83669, U83670, U83671). Plant Physiol. 118: p. 1101.
35. Guan JC, Jinn TC, Yeh CH, Feng SP, Chen YM, Lin CY (2004). Characterization of the genomic structures and selective expression profiles of nine class I small heat shock protein genes clustered on two chromosomes in rice (Oryza sativa L.). Plant Mol. Biol. 56(5): 795-809.
36. Guan JC, Li XH, Zhang QF, Kochert G, Lin CY (2003). Characterization of a unique genomic clone located 5′ upstream of the Oshsp16.9B gene on chromosome 1 in rice (Oryza sativa L. cv Tainung No. 67). Theor. Appl. Gen. 106(3): 503-511.
37. Giaginis C, Daskalopoulou SS, Vgenopoulou S, Sfiniadakis I, Kouraklis G, Theocharis SE (2009). Heat Shock Protein-27, -60 and -90 expression in gastric cancer: association with clinicopathological variables and patient survival. BMC Gastroenterol. 9: 9-14.
38. Han MJ, Lee JW, Lee SY (2005). Enhanced proteome profiling by inhibiting proteolysis with small heat shock proteins. J. Proteome Res. 4: 2429-2434.
39. Hamilton EW, Scott A (2001). Heckathorn Mitochondrial Adaptations to NaCl. Complex I is Protected by Anti-Oxidants and Small Heat Shock Proteins, Whereas Complex II is Protected by Proline and Betaine. Plant Physiol. 126: 1266-1274.
40. Haslbeck M, Kastenmuller A, Buchner J, Weinkauf S, Braun N (2008). Structural Dynamics of Archaeal Small Heat Shock Proteins. J. Mol. Biol. 378(2): 362-374.
41. Heckathorn SA, Downs CA, Coleman JS (1999). Small heat shock proteins protect electron transport in chloroplast and mitochondria during stress. Am. Zool. 39(6): 865-876.
42. Heckathorn SA, Ryan SL, Baylis JA, Dongfang W, Hamilton WE, Cundiff L, Luthe DS (2002). In vivo evidence from an Agrostis stolonifera selection genotype that chloroplast small heat-shock proteins can protect photosystem II during heat stress. Funct. Plant Biol. 29(8): 935-946.
43. Heikkila JJ (2004). Regulation and function of small heat shock protein genes during amphibian development. J. Cell. Biochem. 93(4): 672-680.
44. Hendrick JP, Hartl FU, (1993). Molecular chaperone functions of heatshock proteins. Ann. Rev. Biochem. 62:349-384.
45. Jiao W, Li P, Zhang J, Zhang H, Chang Z (2005). Small heat-shock proteins function in the insoluble protein complex. Biochem. Biophys. Res. Commun. 335(1): 227-231.
46. Klemenz R, Andres AC, Frohli E, Schafer R, Aoyama A (1993). Expression of the murine small heat shock proteins hsp 25 and aB crystallin in the absence of stress. J. Cell Biol. 120: 639-645.
47. Koide TR, Vêncio ZN, Gomes LS (2006). Global Gene Expression Analysis of the Heat Shock Response in the Phytopathogen Xylella fastidiosa. J. Bacteriol. 188: 5821-5830.
48. Ledesma NA, Kawabata S (2004). Effect of high temperature on protein expression in strawberry plants. Biol. Plantarum. 48(1): 73-79.
49. Lee GJ, Pokala N, Vierling E (1995). Structure and in vitro molecular chaperone activity of cytosolic small heat shock proteins from pea. J. Biol. Chem. 270: 0432-10438.
50. Lee U, Ripflorido I, Hong S, Lurkindale J, Waters E, Vierling E (2007). The Arabidopsis ClpB/Hsp100 family of proteins: chaperones for stress and chloroplast development. Plant J. 49: 115-127.
51. Leroux MR, Ma BJ, Batelier Y, Melki R, Candido EP (1997). Unique structural features of a novel class of small heat shock proteins. J. Biol. Chem. 272: 12847-12853.
52. Lindquist S, Craig EA (1988). The heat shock proteins. Ann. Rev. Genet. 22: 631-677.
53. McLemore EC, Tessier DJ, Thresher J, Komalavilas P, Brophy CM (2005). Role of the small heat shock proteins in regulating vascular smooth muscle tone. J. Am. Coll. Surgeons. 201(1): 30-36.
54. Mounier N, Arrigo AP (2002). Actin cytoskeleton and small heat shock proteins: How do they interact? Cell Stress Chap. 7(2): 167-176.
55. Murakami T, Matsuba S, Funatsuki H, Kawaguchi K, Saruyama H, Tanida M, Sato Y (2004). Over expression of small heat shock, sHSP17.7 confers both heat tolerance and UV-B resistance to rice plants. Mol. Breed. 13: 165-175.
56. Nakamoto H, Vigh L (2007). The small heat shock proteins and their clients. Cell. Mol. Life Sci. 64: 294-306.
57. Nover L, Neumann D, Scharf KD (1989). Heat shock and other stress response systems of plants. Springer, N.Y., p. 155.
58. Parcellier A, Schmitt E, Brunet M, Hammann A, Solary E, Garrido C (2005). Small heat shock proteins HSP27 and aB-crystallin: Cytoprotective and oncogenic functions. Antioxid. Redox Signal, 7(4): 404-413.
59. Prandl R, Kloske E Schöffl F (1995). Developmental regulation and tissue-specific differences of heat shock gene expression in transgenic tobacco and Arabidopsis plants. Plant Mol. Biol. 28: 73-82.
60. Plesofsky-Vig N, Vig J, Brambl R (1992). Phylogeny of the alphacrystallin-related heat-shock proteins. J. Mol. Evol. 35: 537-545.
61. Puigderrajols P, Jofre A, Mir G, Pla M, Verdaguer D, Huguet G, Molinas M (2002). Developmentally and stress-induced small heat shock proteins in cork oak somatic embryos. J. Exp. Bot. 53: 1445-1452.
62. Ramakrishna W, Deng Z, Ding CK, Handa AK, Ozminkowski RH (2003). A Novel Small Heat Shock Protein Gene, vis1, contributes to Pectin Depolymerization and Juice Viscosity in Tomato Fruit. Plant Physiol. 131: 725-735.
63. Salinthone S, Tyagi M, Gerthoffer WT (2008). Small heat shock proteins in smooth muscle. Pharmacol. Therapeut. 119(1): 44-54.
64. Sanmiya K, Suzuki K, Tagiri A, Egawa Y, Shono M (2005). Ovule specific expression of the genes for mitochondrial and endoplasmic reticulum localized small heat-shock proteins in tomato flower. Plant Cell, Tissue Organ Cult. 83(3): 245-250.
65. Santoro MG (2000). Heat shock factors and the control of the stress response. Biochem. Pharmacol. 59(1): 55-63.
66. Schlesinger MJ (1990). Heat shock proteins. J. Biol. Chem. 265(21): 12111-12114.
67. Schoffl F, Prandl R, Reindl A (1998). Regulation of the heat shoch response. Plant physiol. 117: 1135-1141.
68. Schubert R, Manteuffel R, Eich J Haeger KP (2002). Molecular characterization and evolution of the cytosolic class II 17.0 kDa small heatshock protein gene family from Picea abies (L.) Karst. Plant Sci. 163(1): 1-12.
69. Siddique M, Port M, Tripp J, Weber C, Zielinski D, Calligaris R, Winkelhaus S, Scharf KD (2003). Tomato heat stress protein Hsp 16.1-CIII represents a member of a new class of nucleocytoplasmic small heat stress proteins in plants. Cell Stress Chap. 8: 381-394.
70. Smale ST, Kadonaga JT (2003). The RNA polymerase II core promoter. Ann. Rev. Biochem. 72: 449-479.
71. Soto A, Allona I, Collada C, Guevara MA, Casado R, Cerezo ER, aragoncillo C, Gomez L (1999). Hetrologus expression of plant small heat shock protein enhances Escherichia coli viability under heat and cold stress. Plant Physiol. 120: 521-526.
72. Sun Y, MacRae TH (2005a). Small heat shock proteins: Molecular structure and chaperone function. Cell. Mol. Life Sci. 62(21): 2460-2476.
73. Sun W, Montagu MV, Verbruggen N (2002). Small heat shock proteins and stress tolerance in plants. Biochem. Biophysica Acta-Gene Struc. Exp. 1577(1): 1-9.
74. Sun Y, MacRae TH (2005b). The small heat shock proteins and their role in human disease. FEBS J. 272(11): 2613-2627.
75. Swamynathan SK, Piatigorsky J (2002). Orientation-dependent influence of an intergenic enhancer on the promoter activity of the divergently transcribed mouse Shsp/aB-crystallin and Mkbp/HspB2 genes. J. Biol. Chem. 277(51): 49700-49706.
76. Trougakos IP, Gonos ES (2006). Regulation of clusterin/apolipoprotein J, a functional homologue to the small heat shock proteins, by oxidative stress in ageing and age-related diseases. Free Rad. Res. 40(12): 1324-1334.
77. Tang D, Khaleque AA, Jones ER, Theriault JR, Li C, Wong WH, Stevenson MA, Calderwood SK (2005). Expression of heat shock proteins and HSP messenger ribonucleic acid in human prostate carcinoma in vitro and in tumors in vivo. Cell Stress Chaperones. 10: 46-59.
78. Van den Ussel P, Norman DG, Quinlan RA (1999). Molecular chaperones: Small heat shock proteins in the limelight. Curr. Biol. 9(3): 103-105.
79. Verschuure P, Croes Y, Ijssel VD, Quinlan RA, De Jong WW, Boelens WC (2002). Translocation of small heat shock proteins to the actin cytoskeleton upon proteasomal inhibition. J. Mol. Cell. Cardiol. 34(2): 117-128.
80. Vierling E (1991). The heat shock response in plants. Ann. Rev. Plant Physiol. Plant Mol. Biol. 4: 579-620.
81. Vierling E (1997). The small heat shock proteins in plants are members of an ancient family of heat induced proteins. Acta Physiol. Plantarum. 19(4): 539-547.
82. Vierling R, Nguyen HT (1992). Heat-shock gene expression in diploid wheat genotypes differing in thermal tolerance. Crop Sci. 32: 370-377.
83. Vinocur B, Altman A (2005). Recent advances in engineering plant tolerance to abiotic stress: achievements and limitations. Curr. Opin. Biotechnol. 16: 123-132.
84. Volkov RA, Panchuk II, Schoffl F (2005). Small heat shock proteins are differentially regulated during pollen development and following heat stress in tobacco. Plant Mol. Biol. 57: 487-502.
85. 2 is required for effective expression of heat shock genes in Arabidopsis. Plant Mol. Biol. 61: 733-746.
86. Walter S, Buchner J (2002). Molecular chaperones-cellular machines for protein folding. Angewandte Chemie. 41(7): 1098-1113.
87. Wang K, Spector A (2001). ATP causes small heat shock proteins to release denatured protein. Eur J. Biochem. 268: 6335-6345.
88. Wang W, Vinocur B, Shoseyov O, Altman A (2004). Role of plant heat shock proteins and molecular chaperons in the abiotic stress response. Trends Plant Sci. 9(5): 1360-1385.
89. Waters ER (1995). The Molecular Evolution of the Small Heat-Shock Proteins in Plants. Genetics, 141: 785-795.
90. Waters ER, Vierling E (1999). Chloroplast small heat shock proteins: Evidence for atypical evolution of an organelle-localized protein. P. Natl. Acad. Sci. USA, 96(25): 14394-14399.
91. Waters ER, Rioflorido I (2007). Evolutionary analysis of the small heat shock proteins in five complete algal genomes. J. Mol. Evol. 65: 162-174.
92. Waters ER, Lee GJ, Vierling E (1996). Evolution, structure and function of the small heat shock proteins in plants. J. Exp. Bot. 47(296): 325-338.
93. Wehmeyer N, Hernandez LD, Finkelstein RR, Vierling E (1996). Synthesis of small heat-shock proteins is part of the developmental program of late seed maturation. Plant Physiol. 112: 747-757.
94. Wehmeyer N, Vierling E (2000). The expression of small heat shock proteins in seeds responds to discrete developmental signals and suggests a general protective role in desiccation tolerance. Plant Physiol. 122: 1099-1108.
95. Wolkers W, Alberda M, Koornneef M, Leon-Kloosterziel K, Hoekstra F (1998). Properties of proteins and the glassy matrix in maturationdefective mutant seeds of Arabidopsis thaliana. Plant J. 16: 133-143.
96. Zou J, Liu A, Chen X, Zhou X, Gao G, Wang W, Zhang X (2009). Expression analysis of nine rice heat shock protein genes under abiotic stresses and ABA treatment. J. Plant Physiol. 166: 851-861.