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Volumn 48, Issue 2, 2010, Pages 86-95

Lens morphogenesis is dependent on Pax6-mediated inhibition of the canonical Wnt/Beta-catenin signaling in the lens surface ectoderm

Author keywords

Lens; Pax6; Wnt catenin signaling

Indexed keywords

BETA CATENIN; DICKKOPF 1 PROTEIN; SECRETED FRIZZLED RELATED PROTEIN 1; SECRETED FRIZZLED RELATED PROTEIN 2; TRANSCRIPTION FACTOR PAX6; WNT PROTEIN;

EID: 77249170249     PISSN: 1526954X     EISSN: 1526968X     Source Type: Journal    
DOI: 10.1002/dvg.20583     Document Type: Article
Times cited : (51)

References (50)
  • 1
    • 1642418216 scopus 로고    scopus 로고
    • Spatial and temporal expression of Wnt and Dickkopf genes during murine lens development
    • Ang SJ, Stump RJ, Lovicu FJ, McAvoy JW. 2004. Spatial and temporal expression of Wnt and Dickkopf genes during murine lens development. Gene Expr Patterns 4:289-295.
    • (2004) Gene Expr Patterns , vol.4 , pp. 289-295
    • Ang, S.J.1    Stump, R.J.2    Lovicu, F.J.3    McAvoy, J.W.4
  • 2
    • 0034312313 scopus 로고    scopus 로고
    • Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye
    • Ashery-Padan R, Marquardt T, Zhou X, Gruss P. 2000. Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye. Genes Dev 14:2701-2711.
    • (2000) Genes Dev , vol.14 , pp. 2701-2711
    • Ashery-Padan, R.1    Marquardt, T.2    Zhou, X.3    Gruss, P.4
  • 3
    • 33749130424 scopus 로고    scopus 로고
    • Lens specification is the ground state of all sensory placodes, from which FGF promotes olfactory identity
    • Bailey AP, Bhattacharyya S, Bronner-Fraser M, Streit A. 2006. Lens specification is the ground state of all sensory placodes, from which FGF promotes olfactory identity. Dev Cell 11:505-517.
    • (2006) Dev Cell , vol.11 , pp. 505-517
    • Bailey, A.P.1    Bhattacharyya, S.2    Bronner-Fraser, M.3    Streit, A.4
  • 4
    • 33846186034 scopus 로고    scopus 로고
    • Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage
    • Blixt A, Landgren H, Johansson BR, Carlsson P. 2007. Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage. Dev Biol 302:218-229.
    • (2007) Dev Biol , vol.302 , pp. 218-229
    • Blixt, A.1    Landgren, H.2    Johansson, B.R.3    Carlsson, P.4
  • 5
    • 0033897180 scopus 로고    scopus 로고
    • Forkhead Foxe3 maps to the dysgenetic lens locus and is critical in lens development and differentiation
    • Brownell I, Dirksen M, Jamrich M. 2000. Forkhead Foxe3 maps to the dysgenetic lens locus and is critical in lens development and differentiation. Genesis 27:81-93.
    • (2000) Genesis , vol.27 , pp. 81-93
    • Brownell, I.1    Dirksen, M.2    Jamrich, M.3
  • 6
    • 11144322833 scopus 로고    scopus 로고
    • Expression of Frizzleds and secreted frizzled-related proteins (Sfrps) during mammalian lens development
    • Chen Y, Stump RJ, Lovicu FJ, McAvoy JW. 2004. Expression of Frizzleds and secreted frizzled-related proteins (Sfrps) during mammalian lens development. Int J Dev Biol 48:867-877.
    • (2004) Int J Dev Biol , vol.48 , pp. 867-877
    • Chen, Y.1    Stump, R.J.2    Lovicu, F.J.3    McAvoy, J.W.4
  • 7
    • 0035184055 scopus 로고    scopus 로고
    • Early eye development in vertebrates
    • Chow RL, Lang RA. 2001. Early eye development in vertebrates. Annu Rev Cell Dev Biol 17:255-296.
    • (2001) Annu Rev Cell Dev Biol , vol.17 , pp. 255-296
    • Chow, R.L.1    Lang, R.A.2
  • 8
    • 0034121519 scopus 로고    scopus 로고
    • Different roles for Pax6 in the optic vesicle and facial epithelium mediate early morphogenesis of the murine eye
    • Collinson JM, Hill RE, West JD. 2000. Different roles for Pax6 in the optic vesicle and facial epithelium mediate early morphogenesis of the murine eye. Development 127:945-956.
    • (2000) Development , vol.127 , pp. 945-956
    • Collinson, J.M.1    Hill, R.E.2    West, J.D.3
  • 9
    • 0032718124 scopus 로고    scopus 로고
    • Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation
    • DasGupta R, Fuchs E. 1999. Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation. Development 126:4557-4568.
    • (1999) Development , vol.126 , pp. 4557-4568
    • DasGupta, R.1    Fuchs, E.2
  • 11
    • 7444235421 scopus 로고    scopus 로고
    • Characterisation of the Wnt antagonists and their response to conditionally activated Wnt signalling in the developing mouse forebrain
    • Diep DB, Hoen N, Backman M, Machon O, Krauss S. 2004. Characterisation of the Wnt antagonists and their response to conditionally activated Wnt signalling in the developing mouse forebrain. Brain Res Dev Brain Res 153:261-270.
    • (2004) Brain Res Dev Brain Res , vol.153 , pp. 261-270
    • Diep, D.B.1    Hoen, N.2    Backman, M.3    Machon, O.4    Krauss, S.5
  • 12
  • 13
    • 0036177940 scopus 로고    scopus 로고
    • Prox1 is differentially localized during lens development
    • Duncan MK, Cui W, Oh DJ, Tomarev SI. 2002. Prox1 is differentially localized during lens development. Mech Dev 112:195-198.
    • (2002) Mech Dev , vol.112 , pp. 195-198
    • Duncan, M.K.1    Cui, W.2    Oh, D.J.3    Tomarev, S.I.4
  • 14
    • 33845391367 scopus 로고    scopus 로고
    • Pax6 is required for delta-catenin/neurojugin expression during retinal, cerebellar and cortical development in mice
    • Duparc RH, Boutemmine D, Champagne MP, Tetreault N, Bernier G. 2006. Pax6 is required for delta-catenin/neurojugin expression during retinal, cerebellar and cortical development in mice. Dev Biol 300:647-655.
    • (2006) Dev Biol , vol.300 , pp. 647-655
    • Duparc, R.H.1    Boutemmine, D.2    Champagne, M.P.3    Tetreault, N.4    Bernier, G.5
  • 17
    • 0032430772 scopus 로고    scopus 로고
    • BMP4 is essential for lens induction in the mouse embryo
    • Furuta Y, Hogan BL. 1998. BMP4 is essential for lens induction in the mouse embryo. Genes Dev 12:3764-3775.
    • (1998) Genes Dev , vol.12 , pp. 3764-3775
    • Furuta, Y.1    Hogan, B.L.2
  • 18
    • 42649083977 scopus 로고    scopus 로고
    • The canonical Wnt signaling antagonist DKK2 is an essential effector of PITX2 function during normal eye development
    • Gage PJ, Qian M, Wu D, Rosenberg KI. 2008. The canonical Wnt signaling antagonist DKK2 is an essential effector of PITX2 function during normal eye development. Dev Biol 317:310-324.
    • (2008) Dev Biol , vol.317 , pp. 310-324
    • Gage, P.J.1    Qian, M.2    Wu, D.3    Rosenberg, K.I.4
  • 20
    • 0029002548 scopus 로고
    • The role of Pax-6 in eye and nasal development
    • Grindley JC, Davidson DR, Hill RE. 1995. The role of Pax-6 in eye and nasal development. Development 121:1433-1442.
    • (1995) Development , vol.121 , pp. 1433-1442
    • Grindley, J.C.1    Davidson, D.R.2    Hill, R.E.3
  • 21
    • 0029054291 scopus 로고
    • Pax6: More than meets the eye
    • Hanson I, van Heyningen V. 1995. Pax6: More than meets the eye. Trends Genet 11:268-272.
    • (1995) Trends Genet , vol.11 , pp. 268-272
    • Hanson, I.1    van Heyningen, V.2
  • 22
    • 0033230616 scopus 로고    scopus 로고
    • Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene
    • Harada N, Tamai Y, Ishikawa T, Sauer B, Takaku K, Oshima M, Taketo MM. 1999. Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene. EMBO J 18:5931-5942.
    • (1999) EMBO J , vol.18 , pp. 5931-5942
    • Harada, N.1    Tamai, Y.2    Ishikawa, T.3    Sauer, B.4    Takaku, K.5    Oshima, M.6    Taketo, M.M.7
  • 24
    • 0022558958 scopus 로고
    • Small eyes (Sey): A homozygous lethal mutation on chromosome 2 which affects the differentiation of both lens and nasal placodes in the mouse
    • Hogan BL, Horsburgh G, Cohen J, Hetherington CM, Fisher G, Lyon MF. 1986. Small eyes (Sey): A homozygous lethal mutation on chromosome 2 which affects the differentiation of both lens and nasal placodes in the mouse. J Embryol Exp Morphol 97:95-110.
    • (1986) J Embryol Exp Morphol , vol.97 , pp. 95-110
    • Hogan, B.L.1    Horsburgh, G.2    Cohen, J.3    Hetherington, C.M.4    Fisher, G.5    Lyon, M.F.6
  • 25
    • 0036148208 scopus 로고    scopus 로고
    • Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway
    • Jho EH, Zhang T, Domon C, Joo CK, Freund JN, Costantini F. 2002. Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway. Mol Cell Biol 22:1172-1183.
    • (2002) Mol Cell Biol , vol.22 , pp. 1172-1183
    • Jho, E.H.1    Zhang, T.2    Domon, C.3    Joo, C.K.4    Freund, J.N.5    Costantini, F.6
  • 26
    • 0032895297 scopus 로고    scopus 로고
    • Distinct cis-essential modules direct the time-space pattern of the Pax6 gene activity
    • Kammandel B, Chowdhury K, Stoykova A, Aparicio S, Brenner S, Gruss P. 1999. Distinct cis-essential modules direct the time-space pattern of the Pax6 gene activity. Dev Biol 205:79-97.
    • (1999) Dev Biol , vol.205 , pp. 79-97
    • Kammandel, B.1    Chowdhury, K.2    Stoykova, A.3    Aparicio, S.4    Brenner, S.5    Gruss, P.6
  • 28
    • 22144486514 scopus 로고    scopus 로고
    • Pax genes in eye development and evolution
    • Kozmik Z. 2005. Pax genes in eye development and evolution. Curr Opin Genet Dev 15:430-438.
    • (2005) Curr Opin Genet Dev , vol.15 , pp. 430-438
    • Kozmik, Z.1
  • 30
    • 0037664300 scopus 로고    scopus 로고
    • Characterization of Wnt signaling components and activation of the Wnt canonical pathway in the murine retina
    • Liu H, Mohamed O, Dufort D, Wallace VA. 2003. Characterization of Wnt signaling components and activation of the Wnt canonical pathway in the murine retina. Dev Dyn 227:323-334.
    • (2003) Dev Dyn , vol.227 , pp. 323-334
    • Liu, H.1    Mohamed, O.2    Dufort, D.3    Wallace, V.A.4
  • 32
    • 14844323116 scopus 로고    scopus 로고
    • Growth factor regulation of lens development
    • Lovicu FJ, McAvoy JW. 2005. Growth factor regulation of lens development. Dev Biol 280:1-14.
    • (2005) Dev Biol , vol.280 , pp. 1-14
    • Lovicu, F.J.1    McAvoy, J.W.2
  • 34
    • 35348900147 scopus 로고    scopus 로고
    • A dynamic gradient of Wnt signaling controls initiation of neurogenesis in the mammalian cortex and cellular specification in the hippocampus
    • Machon O, Backman M, Machonova O, Kozmik Z, Vacik T, Andersen L, Krauss S. 2007. A dynamic gradient of Wnt signaling controls initiation of neurogenesis in the mammalian cortex and cellular specification in the hippocampus. Dev Biol 311:223-237.
    • (2007) Dev Biol , vol.311 , pp. 223-237
    • Machon, O.1    Backman, M.2    Machonova, O.3    Kozmik, Z.4    Vacik, T.5    Andersen, L.6    Krauss, S.7
  • 37
    • 0034020651 scopus 로고    scopus 로고
    • Regulation of eye formation by the Rx and pax6 homeobox genes
    • Mathers PH, Jamrich M. 2000. Regulation of eye formation by the Rx and pax6 homeobox genes. Cell Mol Life Sci 57:186-194.
    • (2000) Cell Mol Life Sci , vol.57 , pp. 186-194
    • Mathers, P.H.1    Jamrich, M.2
  • 38
    • 0031001710 scopus 로고    scopus 로고
    • The Rx homeobox gene is essential for vertebrate eye development
    • Mathers PH, Grinberg A, Mahon KA, Jamrich M. 1997. The Rx homeobox gene is essential for vertebrate eye development. Nature 387:603-607.
    • (1997) Nature , vol.387 , pp. 603-607
    • Mathers, P.H.1    Grinberg, A.2    Mahon, K.A.3    Jamrich, M.4
  • 39
  • 40
    • 25844490866 scopus 로고    scopus 로고
    • The duality of beta-catenin function: A requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm
    • Smith AN, Miller LA, Song N, Taketo MM, Lang RA. 2005. The duality of beta-catenin function: A requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm. Dev Biol 285:477-489.
    • (2005) Dev Biol , vol.285 , pp. 477-489
    • Smith, A.N.1    Miller, L.A.2    Song, N.3    Taketo, M.M.4    Lang, R.A.5
  • 41
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter strain
    • Soriano P. 1999. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 21:70-71.
    • (1999) Nat Genet , vol.21 , pp. 70-71
    • Soriano, P.1
  • 44
    • 0034526271 scopus 로고    scopus 로고
    • Dosage requirement and allelic expression of PAX6 during lens placode formation
    • van Raamsdonk CD, Tilghman SM. 2000. Dosage requirement and allelic expression of PAX6 during lens placode formation. Development 127:5439-5448.
    • (2000) Development , vol.127 , pp. 5439-5448
    • van Raamsdonk, C.D.1    Tilghman, S.M.2
  • 46
    • 0033018615 scopus 로고    scopus 로고
    • Prox1 function is crucial for mouse lens-fibre elongation
    • Wigle JT, Chowdhury K, Gruss P, Oliver G. 1999. Prox1 function is crucial for mouse lens-fibre elongation. Nat Genet 21:318-322.
    • (1999) Nat Genet , vol.21 , pp. 318-322
    • Wigle, J.T.1    Chowdhury, K.2    Gruss, P.3    Oliver, G.4
  • 49
    • 27744542002 scopus 로고    scopus 로고
    • Regulation of ocular lens development by Smad-interacting protein 1 involving Foxe3 activation
    • Yoshimoto A, Saigou Y, Higashi Y, Kondoh H. 2005. Regulation of ocular lens development by Smad-interacting protein 1 involving Foxe3 activation. Development 132:4437-4448.
    • (2005) Development , vol.132 , pp. 4437-4448
    • Yoshimoto, A.1    Saigou, Y.2    Higashi, Y.3    Kondoh, H.4
  • 50
    • 0037102552 scopus 로고    scopus 로고
    • Meis homeoproteins directly regulate Pax6 during vertebrate lens morphogenesis
    • Zhang X, Friedman A, Heaney S, Purcell P, Maas RL. 2002. Meis homeoproteins directly regulate Pax6 during vertebrate lens morphogenesis. Genes Dev 16:2097-2107.
    • (2002) Genes Dev , vol.16 , pp. 2097-2107
    • Zhang, X.1    Friedman, A.2    Heaney, S.3    Purcell, P.4    Maas, R.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.