메뉴 건너뛰기




Volumn 57, Issue 2, 2000, Pages 186-194

Regulation of eye formation by the Rx and pax6 homeobox genes

Author keywords

Development; Embryo; Eye; Homeobox; Pax6; Rx; Transcription factor

Indexed keywords

BETA ARRESTIN; EPIDERMAL GROWTH FACTOR; INTERPHOTORECEPTOR RETINOID BINDING PROTEIN; RNA; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR ALPHA;

EID: 0034020651     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00000683     Document Type: Review
Times cited : (90)

References (94)
  • 1
    • 0026340588 scopus 로고
    • Pax-6, a murine paired box gene, is expressed in the developing CNS
    • 1 Walther C. and Gruss P. (1991) Pax-6, a murine paired box gene, is expressed in the developing CNS. Development 113: 1435-1449
    • (1991) Development , vol.113 , pp. 1435-1449
    • Walther, C.1    Gruss, P.2
  • 2
    • 0026315044 scopus 로고
    • Positional cloning and characterization of a paired box-and homeobox-containing gene from the aniridia region
    • 2 Ton C. C., Hirvonen H., Miwa H., Weil M. M., Monaghan P., Jordan T, et al. (1991) Positional cloning and characterization of a paired box-and homeobox-containing gene from the aniridia region. Cell 67: 1059-1074
    • (1991) Cell , vol.67 , pp. 1059-1074
    • Ton, C.C.1    Hirvonen, H.2    Miwa, H.3    Weil, M.M.4    Monaghan, P.5    Jordan, T.6
  • 3
    • 0027965633 scopus 로고
    • Homology of the eyeless gene of Drosophila to the small eye gene in mice and aniridia in humans
    • 3 Quiring R., Walldorf U., Kloter U. and Gehring W. J. (1994) Homology of the eyeless gene of Drosophila to the Small eye gene in mice and aniridia in humans. Science 265: 785-789
    • (1994) Science , vol.265 , pp. 785-789
    • Quiring, R.1    Walldorf, U.2    Kloter, U.3    Gehring, W.J.4
  • 4
    • 0029149918 scopus 로고
    • Specification of sense-organ identity by a Caenorhabditis elegans Pax-6 homologue
    • 4 Zhang Y. and Emmons S. W. (1995) Specification of sense-organ identity by a Caenorhabditis elegans Pax-6 homologue. Nature 377: 55-59
    • (1995) Nature , vol.377 , pp. 55-59
    • Zhang, Y.1    Emmons, S.W.2
  • 5
    • 0029155709 scopus 로고
    • Patterning of the Caenorhabditis elegans head region by the Pax-6 family member vab-3
    • 5 Chisholm A. D. and Horvitz H. R. (1995) Patterning of the Caenorhabditis elegans head region by the Pax-6 family member vab-3. Nature 377: 52-55
    • (1995) Nature , vol.377 , pp. 52-55
    • Chisholm, A.D.1    Horvitz, H.R.2
  • 7
    • 0031038186 scopus 로고    scopus 로고
    • Conservation of Pax-6 in a lower chordate, the ascidian Phallusia mammillata
    • 7 Glardon S., Callaerts P., Halder G. and Gehring W. J. (1997) Conservation of Pax-6 in a lower chordate, the ascidian Phallusia mammillata. Development 124: 817-825
    • (1997) Development , vol.124 , pp. 817-825
    • Glardon, S.1    Callaerts, P.2    Halder, G.3    Gehring, W.J.4
  • 8
    • 0031876653 scopus 로고    scopus 로고
    • Isolation and developmental expression of the amphioxus Pax-6 gene (AmphiPax-6): Insights into eye and photoreceptor evolution
    • 8 Glardon S., Holland L. Z., Gehring W. J. and Holland N. D. (1998) Isolation and developmental expression of the amphioxus Pax-6 gene (AmphiPax-6): insights into eye and photoreceptor evolution. Development 125: 2701-2710
    • (1998) Development , vol.125 , pp. 2701-2710
    • Glardon, S.1    Holland, L.Z.2    Gehring, W.J.3    Holland, N.D.4
  • 9
  • 10
    • 0033105606 scopus 로고    scopus 로고
    • Twin of eyeless, a second Pax-6 gene of Drosophila, acts upstream of eyeless in the control of eye development
    • 10 Czerny T., Halder G., Kloter U., Souabni A., Gehring W. J. and Busslinger M. (1999) twin of eyeless, a second Pax-6 gene of Drosophila, acts upstream of eyeless in the control of eye development. Mol. Cell 3: 297-307
    • (1999) Mol. Cell , vol.3 , pp. 297-307
    • Czerny, T.1    Halder, G.2    Kloter, U.3    Souabni, A.4    Gehring, W.J.5    Busslinger, M.6
  • 11
    • 0031043386 scopus 로고    scopus 로고
    • Xrxl, a novel Xenopus homeobox gene expressed during eye and pineal gland development
    • 11 Casarosa S., Andreazzoli M., Simeone A. and Barsacchi G. (1997) Xrxl, a novel Xenopus homeobox gene expressed during eye and pineal gland development. Mech. Dev. 61: 187-198
    • (1997) Mech. Dev. , vol.61 , pp. 187-198
    • Casarosa, S.1    Andreazzoli, M.2    Simeone, A.3    Barsacchi, G.4
  • 12
    • 0030979167 scopus 로고    scopus 로고
    • Proc
    • 12 Furukawa T., Kozak C. A. and Cepko C. L. (1997) rax, a novel paired-type homeobox gene, shows expression in the anterior neural fold and developing retina. Proc. Natl. Acad. Sci. USA 94: 3088-3093
    • (1997) Natl. Acad. Sci. USA , vol.94 , pp. 3088-3093
    • Furukawa, T.1    Kozak, C.A.2    Cepko, C.L.3
  • 13
    • 0031001710 scopus 로고    scopus 로고
    • The Rx homeobox gene is essential for vertebrate eye development
    • 13 Mathers P. H., Grinberg A., Mahon K. A. and Jamrich M. (1997) The Rx homeobox gene is essential for vertebrate eye development. Nature 387: 603-607
    • (1997) Nature , vol.387 , pp. 603-607
    • Mathers, P.H.1    Grinberg, A.2    Mahon, K.A.3    Jamrich, M.4
  • 14
    • 0000071294 scopus 로고
    • A comprehensive classification of homeobox genes
    • Duboule D. (ed.), Oxford University Press, New York
    • 14 Bürglin T. R. (1994) A comprehensive classification of homeobox genes. In: Guidebook to Homeobox Genes, pp. 25-73, Duboule D. (ed.), Oxford University Press, New York
    • (1994) Guidebook to Homeobox Genes , pp. 25-73
    • Bürglin, T.R.1
  • 16
    • 0030581164 scopus 로고    scopus 로고
    • Influence of PAX6 gene dosage on development: Overexpression causes severe eye abnormalities
    • 16 Schedl A., Ross A., Lee M., Engelkamp D., Rashbass P., Heyningen V. van et al. (1996) Influence of PAX6 gene dosage on development: overexpression causes severe eye abnormalities. Cell 86: 71-82
    • (1996) Cell , vol.86 , pp. 71-82
    • Schedl, A.1    Ross, A.2    Lee, M.3    Engelkamp, D.4    Rashbass, P.5    Van Heyningen, V.6
  • 17
    • 0024506003 scopus 로고
    • Differential gene expression in the anterior neural plate during gastrulation of Xenopus laevis
    • 17 Jamrich M. and Sato S. (1989) Differential gene expression in the anterior neural plate during gastrulation of Xenopus laevis. Development 105: 779-786
    • (1989) Development , vol.105 , pp. 779-786
    • Jamrich, M.1    Sato, S.2
  • 18
    • 0031043536 scopus 로고    scopus 로고
    • A single morphogenetic field gives rise to two retina primordia under the influence of the prechordal plate
    • 18 Li H., Tierney C., Wen L., Wu J. Y. and Rao Y. (1997) A single morphogenetic field gives rise to two retina primordia under the influence of the prechordal plate. Development 124: 603-615
    • (1997) Development , vol.124 , pp. 603-615
    • Li, H.1    Tierney, C.2    Wen, L.3    Wu, J.Y.4    Rao, Y.5
  • 19
    • 0031035640 scopus 로고    scopus 로고
    • Xenopus Pax-6 and retinal development
    • 19 Hirsch N. and Harris W. A. (1997) Xenopus Pax-6 and retinal development. J. Neurobiol. 32: 45-61
    • (1997) J. Neurobiol. , vol.32 , pp. 45-61
    • Hirsch, N.1    Harris, W.A.2
  • 20
    • 0344731346 scopus 로고    scopus 로고
    • Expression of three Rx homeobox genes in embryonic and adult zebrafish
    • 20 Chuang J. C., Mathers P. H. and Raymond P. A. (1999) Expression of three Rx homeobox genes in embryonic and adult zebrafish. Mech. Dev. 84: 195-198
    • (1999) Mech. Dev. , vol.84 , pp. 195-198
    • Chuang, J.C.1    Mathers, P.H.2    Raymond, P.A.3
  • 21
    • 0032967757 scopus 로고    scopus 로고
    • Expression of the medaka (Oryzias latipes) Ol-Rx3 paired-like gene in two diencephalic derivatives, the eye and the hypothalamus
    • 21 Desehet K., Bourrat F., Ristoratore F., Chourrout D. and Joly J. S. (1999) Expression of the medaka (Oryzias latipes) Ol-Rx3 paired-like gene in two diencephalic derivatives, the eye and the hypothalamus. Mech. Dev. 83: 179-182
    • (1999) Mech. Dev. , vol.83 , pp. 179-182
    • Desehet, K.1    Bourrat, F.2    Ristoratore, F.3    Chourrout, D.4    Joly, J.S.5
  • 22
    • 0033167238 scopus 로고    scopus 로고
    • Identification of chick rax/rx genes with overlapping patterns of expression during early eye and brain development
    • 22 Ohuchi H., Tomonari S., Itoh H., Mikawa T. and Noji S. (1999) Identification of chick rax/rx genes with overlapping patterns of expression during early eye and brain development. Mech. Dev. 85: 193-195
    • (1999) Mech. Dev. , vol.85 , pp. 193-195
    • Ohuchi, H.1    Tomonari, S.2    Itoh, H.3    Mikawa, T.4    Noji, S.5
  • 23
    • 23444441161 scopus 로고
    • Pax-6 is first expressed in a region of ectoderm anterior to the early neural plate: Implications for stepwise determination of the lens
    • 23 Li H. S., Yang J. M., Jacobson R. D., Pasko D. and Sundin O. (1994) Pax-6 is first expressed in a region of ectoderm anterior to the early neural plate: implications for stepwise determination of the lens. Dev. Biol. 162: 181-194
    • (1994) Dev. Biol. , vol.162 , pp. 181-194
    • Li, H.S.1    Yang, J.M.2    Jacobson, R.D.3    Pasko, D.4    Sundin, O.5
  • 24
    • 0029002548 scopus 로고
    • The role of Pax-6 in eye and nasal development
    • 24 Grindley J. C., Davidson D. R. and Hill R. E. (1995) The role of Pax-6 in eye and nasal development. Development 121: 1433-1442
    • (1995) Development , vol.121 , pp. 1433-1442
    • Grindley, J.C.1    Davidson, D.R.2    Hill, R.E.3
  • 25
    • 0029777408 scopus 로고    scopus 로고
    • Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
    • 25 Chiang C., Litingtung Y., Lee E., Young K. E., Corden J. L., Westphal H. et al. (1996) Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature 383: 407-413
    • (1996) Nature , vol.383 , pp. 407-413
    • Chiang, C.1    Litingtung, Y.2    Lee, E.3    Young, K.E.4    Corden, J.L.5    Westphal, H.6
  • 26
    • 0028864430 scopus 로고
    • Midline signalling is required for Pax gene regulation and patterning of the eyes
    • 26 Macdonald R., Barth K. A., Xu Q., Holder N., Mikkola I. and Wilson S. W. (1995) Midline signalling is required for Pax gene regulation and patterning of the eyes. Development 121: 3267-3278
    • (1995) Development , vol.121 , pp. 3267-3278
    • Macdonald, R.1    Barth, K.A.2    Xu, Q.3    Holder, N.4    Mikkola, I.5    Wilson, S.W.6
  • 27
  • 29
    • 0032559307 scopus 로고    scopus 로고
    • Positional cloning identifies zebrafish one-eyed pinhead as a permissive EGF-related ligand required during gastrulation
    • 29 Zhang J., Talbot W. S. and Schier A. F. (1998) Positional cloning identifies zebrafish one-eyed pinhead as a permissive EGF-related ligand required during gastrulation. Cell 92: 241-251
    • (1998) Cell , vol.92 , pp. 241-251
    • Zhang, J.1    Talbot, W.S.2    Schier, A.F.3
  • 30
    • 0033515638 scopus 로고    scopus 로고
    • The EGF-CFC protein one-eyed pinhead is essential for nodal signaling
    • 30 Gritsman K., Zhang J., Cheng S., Heckscher E., Talbot W. S. and Schier A. F. (1999) The EGF-CFC protein one-eyed pinhead is essential for nodal signaling. Cell 97: 121-132
    • (1999) Cell , vol.97 , pp. 121-132
    • Gritsman, K.1    Zhang, J.2    Cheng, S.3    Heckscher, E.4    Talbot, W.S.5    Schier, A.F.6
  • 31
    • 0023787751 scopus 로고
    • Small eye (Sey): A mouse model for the genetic analysis of craniofacial abnormalities
    • 31 Hogan B. L., Hirst E. M., Horsburgh G. and Hetherington C. M. (1988) Small eye (Sey): a mouse model for the genetic analysis of craniofacial abnormalities. Development 103: 115-119
    • (1988) Development , vol.103 , pp. 115-119
    • Hogan, B.L.1    Hirst, E.M.2    Horsburgh, G.3    Hetherington, C.M.4
  • 32
    • 0030696668 scopus 로고    scopus 로고
    • Genetic background effects on dental and other craniofacial abnormalities in homozygous small eye (Pax6Sey/Pax6Sey) mice
    • 32 Quinn J. C., West J. D. and Kaufman M. H. (1997) Genetic background effects on dental and other craniofacial abnormalities in homozygous small eye (Pax6Sey/Pax6Sey) mice. Anat. Embryol. (Berl.) 196: 311-321
    • (1997) Anat. Embryol. (Berl.) , vol.196 , pp. 311-321
    • Quinn, J.C.1    West, J.D.2    Kaufman, M.H.3
  • 33
    • 0014323345 scopus 로고
    • Differential addition of cells to the retina in Rana pipiens tadpoles
    • 33 Hollyfield J. G. (1968) Differential addition of cells to the retina in Rana pipiens tadpoles. Dev. Biol. 18: 163-179
    • (1968) Dev. Biol. , vol.18 , pp. 163-179
    • Hollyfield, J.G.1
  • 34
    • 0023869524 scopus 로고
    • Multipotent precursors can give rise to all major cell types of the frog retina
    • 34 Wetts R. and Fraser S. E. (1988) Multipotent precursors can give rise to all major cell types of the frog retina. Science 239: 1142-1145
    • (1988) Science , vol.239 , pp. 1142-1145
    • Wetts, R.1    Fraser, S.E.2
  • 35
    • 0023967713 scopus 로고
    • Cellular determination in the Xenopus retina is independent of lineage and birth date
    • 35 Holt C. E., Bertsch T. W., Ellis H. M. and Harris W. A. (1988) Cellular determination in the Xenopus retina is independent of lineage and birth date. Neuron 1: 15-26
    • (1988) Neuron , vol.1 , pp. 15-26
    • Holt, C.E.1    Bertsch, T.W.2    Ellis, H.M.3    Harris, W.A.4
  • 36
    • 0024438547 scopus 로고
    • Cell lineage analysis reveals multipotent precursors in the ciliary margin of the frog retina
    • 36 Wetts R., Serbedzija G. N. and Fraser S. E. (1989) Cell lineage analysis reveals multipotent precursors in the ciliary margin of the frog retina. Dev. Biol. 136: 254-263
    • (1989) Dev. Biol. , vol.136 , pp. 254-263
    • Wetts, R.1    Serbedzija, G.N.2    Fraser, S.E.3
  • 37
    • 0032528384 scopus 로고    scopus 로고
    • The genetic sequence of retinal development in the ciliary margin of the Xenopus eye
    • 37 Perron M., Kanekar S., Vetter M. L. and Harris W. A. (1998) The genetic sequence of retinal development in the ciliary margin of the Xenopus eye. Dev. Biol. 199: 185-200
    • (1998) Dev. Biol. , vol.199 , pp. 185-200
    • Perron, M.1    Kanekar, S.2    Vetter, M.L.3    Harris, W.A.4
  • 38
    • 0029670954 scopus 로고    scopus 로고
    • Antibodies against Pax6 immunostain amacrine and ganglion cells and neuronal progenitors, but not rod precursors, in the normal and regenerating retina of the goldfish
    • 38 Hitchcock P. F., Macdonald R. E., VanDeRyt J. T. and Wilson S. W. (1996) Antibodies against Pax6 immunostain amacrine and ganglion cells and neuronal progenitors, but not rod precursors, in the normal and regenerating retina of the goldfish. J. Neurobiol. 29: 399-413
    • (1996) J. Neurobiol. , vol.29 , pp. 399-413
    • Hitchcock, P.F.1    Macdonald, R.E.2    VanDeRyt, J.T.3    Wilson, S.W.4
  • 39
    • 0017729874 scopus 로고
    • Growth of the adult goldfish eye. III. Source of the new retinal cells
    • 39 Johns P. R. (1977) Growth of the adult goldfish eye. III. Source of the new retinal cells. J. Comp. Neurol. 176: 343-357
    • (1977) J. Comp. Neurol. , vol.176 , pp. 343-357
    • Johns, P.R.1
  • 40
    • 0025579965 scopus 로고
    • Teleost vision: Seeing while growing
    • 40 Fernald R. D. (1990) Teleost vision: seeing while growing. J. Exp. Zool. Suppl. 5: 167-180
    • (1990) J. Exp. Zool. Suppl. , vol.5 , pp. 167-180
    • Fernald, R.D.1
  • 41
    • 0032478268 scopus 로고    scopus 로고
    • Isolation of a Drosophila homolog of the vertebrate homeobox gene Rx and its possible role in brain and eye development
    • 41 Eggert T., Hauck B., Hildebrandt N., Gehring W. J. and Walldorf U. (1998) Isolation of a Drosophila homolog of the vertebrate homeobox gene Rx and its possible role in brain and eye development. Proc. Natl. Acad. Sci. USA 95: 2343-2348
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 2343-2348
    • Eggert, T.1    Hauck, B.2    Hildebrandt, N.3    Gehring, W.J.4    Walldorf, U.5
  • 43
    • 0031033915 scopus 로고    scopus 로고
    • The Pax-6 homeobox gene is expressed throughout the corneal and conjunctival epithelia
    • 43 Koroma B. M., Yang J. M. and Sundin O. H. (1997) The Pax-6 homeobox gene is expressed throughout the corneal and conjunctival epithelia. Invest. Ophthalmol. Vis. Sci. 38: 108-120
    • (1997) Invest. Ophthalmol. Vis. Sci. , vol.38 , pp. 108-120
    • Koroma, B.M.1    Yang, J.M.2    Sundin, O.H.3
  • 45
    • 0033977329 scopus 로고    scopus 로고
    • Both PCE-I/RX and OTX/CRX interactions are necessary for photoreceptor-specific gene expression
    • 45 Kimura A., Singh D., Wawrousek E. F., Kikuchi M., Nakamura M. and Shinohara T. (2000) Both PCE-I/RX and OTX/CRX interactions are necessary for photoreceptor-specific gene expression. J. Biol. Chem. 275: 1152-1160
    • (2000) J. Biol. Chem. , vol.275 , pp. 1152-1160
    • Kimura, A.1    Singh, D.2    Wawrousek, E.F.3    Kikuchi, M.4    Nakamura, M.5    Shinohara, T.6
  • 46
    • 0027453705 scopus 로고
    • A universal target sequence is bound in vitro by diverse homeodomains
    • 46 Kalionis B. and O'Farrell P. H. (1993) A universal target sequence is bound in vitro by diverse homeodomains. Mech. Dev. 43: 57-70
    • (1993) Mech. Dev. , vol.43 , pp. 57-70
    • Kalionis, B.1    O'Farrell, P.H.2
  • 47
    • 0025741231 scopus 로고
    • Characterization of developmentally regulated and retina-specific nuclear protein binding to a site in the upstream region of the rat opsin gene
    • 47 Morabito M. A., Yu X. and Barnstable C. J. (1991) Characterization of developmentally regulated and retina-specific nuclear protein binding to a site in the upstream region of the rat opsin gene. J. Biol. Chem. 266: 9667-9672
    • (1991) J. Biol. Chem. , vol.266 , pp. 9667-9672
    • Morabito, M.A.1    Yu, X.2    Barnstable, C.J.3
  • 48
    • 0027240908 scopus 로고
    • The proximal promoter of the mouse arrestin gene directs gene expression in photoreceptor cells and contains an evolutionarily conserved retinal factor-binding site
    • 48 Kikuchi T., Raju K., Breitman M. L. and Shinohara T. (1993) The proximal promoter of the mouse arrestin gene directs gene expression in photoreceptor cells and contains an evolutionarily conserved retinal factor-binding site. Mol. Cell. Biol. 13: 4400-4408
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 4400-4408
    • Kikuchi, T.1    Raju, K.2    Breitman, M.L.3    Shinohara, T.4
  • 49
    • 0032497289 scopus 로고    scopus 로고
    • Erx, a novel retina-specific homeodomain transcription factor, can interact with Ret I/PCEI sites
    • 49 Martinez J. A. and Barnstable C. J. (1998) Erx, a novel retina-specific homeodomain transcription factor, can interact with Ret I/PCEI sites. Biochem. Biophys. Res. Commun. 250: 175-180
    • (1998) Biochem. Biophys. Res. Commun. , vol.250 , pp. 175-180
    • Martinez, J.A.1    Barnstable, C.J.2
  • 50
    • 0030781996 scopus 로고    scopus 로고
    • Crx, a novel otx-like paired-homeodomain protein, binds to and transactivates photoreceptor cell-specific genes
    • 50 Chen S., Wang Q. L., Nie Z., Sun H., Lennon G., Copeland N. G. et al. (1997) Crx, a novel Otx-like paired-homeodomain protein, binds to and transactivates photoreceptor cell-specific genes. Neuron 19: 1017-1030
    • (1997) Neuron , vol.19 , pp. 1017-1030
    • Chen, S.1    Wang, Q.L.2    Nie, Z.3    Sun, H.4    Lennon, G.5    Copeland, N.G.6
  • 51
    • 0030725687 scopus 로고    scopus 로고
    • Crx, a novel otx-like homeobox gene, shows photoreceptor-specific expression and regulates photoreceptor differentiation
    • 51 Furukawa T., Morrow E. M. and Cepko C. L. (1997) Crx, a novel otx-like homeobox gene, shows photoreceptor-specific expression and regulates photoreceptor differentiation. Cell 91: 531-541
    • (1997) Cell , vol.91 , pp. 531-541
    • Furukawa, T.1    Morrow, E.M.2    Cepko, C.L.3
  • 53
    • 0028918392 scopus 로고
    • DNA-binding and transactivation properties of Pax-6: Three amino acids in the paired domain are responsible for the different sequence recognition of Pax-6 and BSAP (Pax-5)
    • 53 Czerny T. and Busslinger M. (1995) DNA-binding and transactivation properties of Pax-6: three amino acids in the paired domain are responsible for the different sequence recognition of Pax-6 and BSAP (Pax-5). Mol. Cell. Biol. 15: 2858-2871
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2858-2871
    • Czerny, T.1    Busslinger, M.2
  • 54
    • 0027332476 scopus 로고
    • Cooperative dimerization of paired class homeo domains on DNA
    • 54 Wilson D., Sheng G., Lecuit T., Dostatni N. and Desplan C. (1993) Cooperative dimerization of paired class homeo domains on DNA. Genes Dev. 7: 2120-2134
    • (1993) Genes Dev. , vol.7 , pp. 2120-2134
    • Wilson, D.1    Sheng, G.2    Lecuit, T.3    Dostatni, N.4    Desplan, C.5
  • 55
    • 0030219742 scopus 로고    scopus 로고
    • Lens development and crystallin gene expression: Many roles for Pax-6
    • 55 Cvekl A. and Piatigorsky J. (1996) Lens development and crystallin gene expression: many roles for Pax-6. Bioessays 18: 621-630
    • (1996) Bioessays , vol.18 , pp. 621-630
    • Cvekl, A.1    Piatigorsky, J.2
  • 56
    • 0031840442 scopus 로고    scopus 로고
    • Dual roles for Pax-6: A transcriptional repressor of lens fiber cell-specific beta-crystallin genes
    • 56 Duncan M. K., Haynes J. I. 2nd, Cvekl A. and Piatigorsky J. (1998) Dual roles for Pax-6: a transcriptional repressor of lens fiber cell-specific beta-crystallin genes. Mol. Cell. Biol. 18: 5579-5586
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 5579-5586
    • Duncan, M.K.1    Haynes J.I. II2    Cvekl, A.3    Piatigorsky, J.4
  • 57
    • 0031736865 scopus 로고    scopus 로고
    • Identification of the cornea-specific keratin 12 promoter by in vivo particle-mediated gene transfer
    • 57 Shiraishi A., Converse R. L., Liu C. Y., Zhou F., Kao C. W. and Kao W. W. (1998) Identification of the cornea-specific keratin 12 promoter by in vivo particle-mediated gene transfer. Invest. Ophthalmol. Vis. Sci. 39: 2554-2561
    • (1998) Invest. Ophthalmol. Vis. Sci. , vol.39 , pp. 2554-2561
    • Shiraishi, A.1    Converse, R.L.2    Liu, C.Y.3    Zhou, F.4    Kao, C.W.5    Kao, W.W.6
  • 58
    • 0033104951 scopus 로고    scopus 로고
    • Corneal epithelium-specific mouse keratin K12 promoter
    • 58 Liu J. J., Kao W. W. and Wilson S. E. (1999) Corneal epithelium-specific mouse keratin K12 promoter. Exp. Eye Res. 68: 295-301
    • (1999) Exp. Eye Res. , vol.68 , pp. 295-301
    • Liu, J.J.1    Kao, W.W.2    Wilson, S.E.3
  • 59
    • 0030923056 scopus 로고    scopus 로고
    • Direct regulation of rhodopsin 1 by Pax6/eyeless in Drosophila: Evidence for a conserved function in photoreceptors
    • 59 Sheng G., Thouvenot E., Schmucker D., Wilson D. S. and Desplan C. (1997) Direct regulation of rhodopsin 1 by Pax6/eyeless in Drosophila: evidence for a conserved function in photoreceptors. Genes Dev. 11: 1122-1131
    • (1997) Genes Dev. , vol.11 , pp. 1122-1131
    • Sheng, G.1    Thouvenot, E.2    Schmucker, D.3    Wilson, D.S.4    Desplan, C.5
  • 60
    • 0033558871 scopus 로고    scopus 로고
    • Six3 overexpression initiates the formation of ectopic retina
    • 60 Loosli F., Winkler S. and Wittbrodt J. (1999) Six3 overexpression initiates the formation of ectopic retina. Genes Dev. 13: 649-654
    • (1999) Genes Dev. , vol.13 , pp. 649-654
    • Loosli, F.1    Winkler, S.2    Wittbrodt, J.3
  • 62
    • 0026345992 scopus 로고
    • Mouse small eye results from mutations in a paired-like homeobox-containing gene
    • 62 Hill R. E., Favor J., Hogan B. L., Ton C. C., Saunders G. F., Hanson I. M. et al. (1991) Mouse small eye results from mutations in a paired-like homeobox-containing gene. Nature 354: 522-525
    • (1991) Nature , vol.354 , pp. 522-525
    • Hill, R.E.1    Favor, J.2    Hogan, B.L.3    Ton, C.C.4    Saunders, G.F.5    Hanson, I.M.6
  • 63
    • 0026501506 scopus 로고
    • [published erratum appears in Nature (1992) 355: 750]
    • (1992) Nature , vol.355 , pp. 750
  • 64
    • 0026949405 scopus 로고
    • Genomic structure, evolutionary conservation and aniridia mutations in the human PAX6 gene
    • 63 Glaser T., Walton D. S. and Maas R. L. (1992) Genomic structure, evolutionary conservation and aniridia mutations in the human PAX6 gene. Nat. Genet. 2: 232-239
    • (1992) Nat. Genet. , vol.2 , pp. 232-239
    • Glaser, T.1    Walton, D.S.2    Maas, R.L.3
  • 65
    • 0028074973 scopus 로고
    • PAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia and central nervous system defects
    • 64 Glaser T., Jepeal L., Edwards J. G., Young S. R., Favor J. and Maas R. L. (1994) PAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia and central nervous system defects. Nat. Genet. 7: 463-471
    • (1994) Nat. Genet. , vol.7 , pp. 463-471
    • Glaser, T.1    Jepeal, L.2    Edwards, J.G.3    Young, S.R.4    Favor, J.5    Maas, R.L.6
  • 66
    • 0027968947 scopus 로고
    • [published erratum appears in Nat. Genet. (1994) 8: 203]
    • (1994) Nat. Genet. , vol.8 , pp. 203
  • 68
    • 0028308664 scopus 로고
    • Mutations at the PAX6 locus are found in heterogeneous anterior segment malformations including Peters' anomaly
    • 66 Hanson I. M., Fletcher J. M., Jordan T., Brown A., Taylor D., Adams R. J. et al. (1994) Mutations at the PAX6 locus are found in heterogeneous anterior segment malformations including Peters' anomaly. Nat. Genet. 6: 168-173
    • (1994) Nat. Genet. , vol.6 , pp. 168-173
    • Hanson, I.M.1    Fletcher, J.M.2    Jordan, T.3    Brown, A.4    Taylor, D.5    Adams, R.J.6
  • 69
    • 0022558958 scopus 로고
    • Small eyes (Sey): A homozygous lethal mutation on chromosome 2 which affects the differentiation of both lens and nasal placodes in the mouse
    • 67 Hogan B. L., Horsburgh G., Cohen J., Hetherington C. M., Fisher G. and Lyon M. F. (1986) Small eyes (Sey): a homozygous lethal mutation on chromosome 2 which affects the differentiation of both lens and nasal placodes in the mouse. J. Embryol. Exp. Morphol. 97: 95-110
    • (1986) J. Embryol. Exp. Morphol. , vol.97 , pp. 95-110
    • Hogan, B.L.1    Horsburgh, G.2    Cohen, J.3    Hetherington, C.M.4    Fisher, G.5    Lyon, M.F.6
  • 70
    • 0025200949 scopus 로고
    • A mouse model of the aniridia-wilms tumor deletion syndrome
    • 68 Glaser T., Lane J. and Housman D. (1990) A mouse model of the aniridia-Wilms tumor deletion syndrome. Science 250: 823-827
    • (1990) Science , vol.250 , pp. 823-827
    • Glaser, T.1    Lane, J.2    Housman, D.3
  • 71
    • 0029979219 scopus 로고    scopus 로고
    • Multiple functions for Pax6 in mouse eye and nasal development
    • 69 Quinn J. C., West J. D. and Hill R. E. (1996) Multiple functions for Pax6 in mouse eye and nasal development. Genes Dev. 10: 435-446
    • (1996) Genes Dev. , vol.10 , pp. 435-446
    • Quinn, J.C.1    West, J.D.2    Hill, R.E.3
  • 72
    • 0028944665 scopus 로고
    • Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila
    • 70 Halder G., Callaerts P. and Gehring W. J. (1995) Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila. Science 267: 1788-1792
    • (1995) Science , vol.267 , pp. 1788-1792
    • Halder, G.1    Callaerts, P.2    Gehring, W.J.3
  • 74
    • 13344249785 scopus 로고    scopus 로고
    • Ocular retardation mouse caused by Chx10 homeobox null allele: Impaired retinal progenitor proliferation and bipolar cell differentiation
    • 72 Burmeister M., Novak J., Liang M. Y., Basu S., Ploder L., Hawes N. L. et al. (1996) Ocular retardation mouse caused by Chx10 homeobox null allele: impaired retinal progenitor proliferation and bipolar cell differentiation. Nat. Genet. 12: 376-384
    • (1996) Nat. Genet. , vol.12 , pp. 376-384
    • Burmeister, M.1    Novak, J.2    Liang, M.Y.3    Basu, S.4    Ploder, L.5    Hawes, N.L.6
  • 75
    • 0030767662 scopus 로고    scopus 로고
    • Lhx2, a LIM homeobox gene, is required for eye, forebrain, and definitive erythrocyte development
    • 73 Porter F. D., Drago J., Xu Y., Cheema S. S., Wassif C., Huang S. P. et al. (1997) Lhx2, a LIM homeobox gene, is required for eye, forebrain, and definitive erythrocyte development. Development 124: 2935-2944
    • (1997) Development , vol.124 , pp. 2935-2944
    • Porter, F.D.1    Drago, J.2    Xu, Y.3    Cheema, S.S.4    Wassif, C.5    Huang, S.P.6
  • 76
    • 0028832707 scopus 로고
    • A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye
    • 74 Dudley A. T., Lyons K. M. and Robertson E. J. (1995) A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye. Genes Dev. 9: 2795-2807
    • (1995) Genes Dev. , vol.9 , pp. 2795-2807
    • Dudley, A.T.1    Lyons, K.M.2    Robertson, E.J.3
  • 77
    • 0028882261 scopus 로고
    • BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning
    • 75 Luo G., Hofmann C., Bronckers A. L., Sohocki M., Bradley A. and Karsenty G. (1995) BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning. Genes Dev. 9: 2808-2820
    • (1995) Genes Dev. , vol.9 , pp. 2808-2820
    • Luo, G.1    Hofmann, C.2    Bronckers, A.L.3    Sohocki, M.4    Bradley, A.5    Karsenty, G.6
  • 78
    • 0029977614 scopus 로고    scopus 로고
    • Mammalian hairy and enhancer of split homolog 1 regulates differentiation of retinal neurons and is essential for eye morphogenesis
    • 76 Tomita K., Ishibashi M., Nakahara K., Ang S. L., Nakanishi S., Guillemot F. et al. (1996) Mammalian hairy and Enhancer of split homolog 1 regulates differentiation of retinal neurons and is essential for eye morphogenesis. Neuron 16: 723-734
    • (1996) Neuron , vol.16 , pp. 723-734
    • Tomita, K.1    Ishibashi, M.2    Nakahara, K.3    Ang, S.L.4    Nakanishi, S.5    Guillemot, F.6
  • 80
    • 0025802099 scopus 로고
    • Deletion mapping of a retinal cone-rod dystrophy: Assignment to 18q211
    • 78 Warburg M., Sjo O., Tranebjaerg L. and Fledelius H. C. (1991) Deletion mapping of a retinal cone-rod dystrophy: assignment to 18q211. Am. J. Med. Genet. 39: 288-293
    • (1991) Am. J. Med. Genet. , vol.39 , pp. 288-293
    • Warburg, M.1    Sjo, O.2    Tranebjaerg, L.3    Fledelius, H.C.4
  • 81
    • 0030669568 scopus 로고    scopus 로고
    • Cone-rod dystrophy due to mutations in a novel photoreceptor-specific homeobox gene (CRX) essential for maintenance of the photoreceptor
    • 79 Freund C. L., Gregory-Evans C. Y., Furukawa T., Papaioannou M., Looser J., Ploder L. et al. (1997) Cone-rod dystrophy due to mutations in a novel photoreceptor-specific homeobox gene (CRX) essential for maintenance of the photoreceptor. Cell 91: 543-553
    • (1997) Cell , vol.91 , pp. 543-553
    • Freund, C.L.1    Gregory-Evans, C.Y.2    Furukawa, T.3    Papaioannou, M.4    Looser, J.5    Ploder, L.6
  • 82
    • 0031447030 scopus 로고    scopus 로고
    • Mutations in the cone-rod homeobox gene are associated with the cone-rod dystrophy photoreceptor degeneration
    • 80 Swain P. K., Chen S., Wang Q. L., Affatigato L. M., Coats C. L., Brady K. D. et al. (1997) Mutations in the cone-rod homeobox gene are associated with the cone-rod dystrophy photoreceptor degeneration. Neuron 19: 1329-1336
    • (1997) Neuron , vol.19 , pp. 1329-1336
    • Swain, P.K.1    Chen, S.2    Wang, Q.L.3    Affatigato, L.M.4    Coats, C.L.5    Brady, K.D.6
  • 83
    • 0032037626 scopus 로고    scopus 로고
    • De novo mutations in the CRX homeobox gene associated with leber congenital amaurosis
    • 81 Freund C. L., Wang Q. L., Chen S., Muskat B. L., Wiles C. D., Sheffield V. C. et al. (1998) De novo mutations in the CRX homeobox gene associated with Leber congenital amaurosis. Nat. Genet. 18: 311-312
    • (1998) Nat. Genet. , vol.18 , pp. 311-312
    • Freund, C.L.1    Wang, Q.L.2    Chen, S.3    Muskat, B.L.4    Wiles, C.D.5    Sheffield, V.C.6
  • 84
    • 0026759308 scopus 로고
    • Nested expression domains of four homeobox genes in developing rostral brain
    • 82 Simeone A., Acampora D., Gulisano M., Stornaiuolo A. and Boncinelli E. (1992) Nested expression domains of four homeobox genes in developing rostral brain. Nature 358: 687-690
    • (1992) Nature , vol.358 , pp. 687-690
    • Simeone, A.1    Acampora, D.2    Gulisano, M.3    Stornaiuolo, A.4    Boncinelli, E.5
  • 85
    • 0029617682 scopus 로고
    • Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development
    • 83 Oliver G., Mailhos A., Wehr R., Copeland N. G., Jenkins N. A. and Gruss P. (1995) Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development. Development 121: 4045-4055
    • (1995) Development , vol.121 , pp. 4045-4055
    • Oliver, G.1    Mailhos, A.2    Wehr, R.3    Copeland, N.G.4    Jenkins, N.A.5    Gruss, P.6
  • 87
    • 0028825890 scopus 로고
    • Initiation of anterior head-specific gene expression in uncommitted ectoderm of Xenopus laevis by ammonium chloride
    • 85 Mathers P. H., Miller A., Doniach T., Dirksen M. L. and Jamrich M. (1995) Initiation of anterior head-specific gene expression in uncommitted ectoderm of Xenopus laevis by ammonium chloride. Dev. Biol. 171: 641-654
    • (1995) Dev. Biol. , vol.171 , pp. 641-654
    • Mathers, P.H.1    Miller, A.2    Doniach, T.3    Dirksen, M.L.4    Jamrich, M.5
  • 88
    • 0028908976 scopus 로고
    • Sequence, genomic organization, and expression of the novel homeobox gene Hesxl
    • 86 Thomas P. Q., Johnson B. V., Rathjen J. and Rathjen P. D. (1995) Sequence, genomic organization, and expression of the novel homeobox gene Hesxl. J. Biol. Chem. 270: 3869-3875
    • (1995) J. Biol. Chem. , vol.270 , pp. 3869-3875
    • Thomas, P.Q.1    Johnson, B.V.2    Rathjen, J.3    Rathjen, P.D.4
  • 89
    • 0030068242 scopus 로고    scopus 로고
    • Rpx: A novel anterior-restricted homeobox gene progressively activated in the prechordal plate, anterior neural plate and Rathke's pouch of the mouse embryo
    • 87 Hermesz E., Mackem S. and Mahon K. A. (1996) Rpx: a novel anterior-restricted homeobox gene progressively activated in the prechordal plate, anterior neural plate and Rathke's pouch of the mouse embryo. Development 122: 41-52
    • (1996) Development , vol.122 , pp. 41-52
    • Hermesz, E.1    Mackem, S.2    Mahon, K.A.3
  • 90
    • 0029678243 scopus 로고    scopus 로고
    • The master control gene for morphogenesis and evolution of the eye
    • 88 Gehring W. J. (1996) The master control gene for morphogenesis and evolution of the eye. Genes Cells 1: 11-15
    • (1996) Genes Cells , vol.1 , pp. 11-15
    • Gehring, W.J.1
  • 91
    • 0024337818 scopus 로고
    • Progressive determination during formation of the anteroposterior axis in Xenopus laevis
    • 89 Sive H. L., Hattori K. and Weintraub H. (1989) Progressive determination during formation of the anteroposterior axis in Xenopus laevis. Cell 58: 171-180
    • (1989) Cell , vol.58 , pp. 171-180
    • Sive, H.L.1    Hattori, K.2    Weintraub, H.3
  • 92
    • 0027967380 scopus 로고
    • Xenopus chordin: A novel dorsalizing factor activated by organizer-specific homeobox genes
    • 90 Sasai Y., Lu B., Steinbeisser H., Geissert D., Gont L. K. and De Robertis E. M. (1994) Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes. Cell 79: 779-790
    • (1994) Cell , vol.79 , pp. 779-790
    • Sasai, Y.1    Lu, B.2    Steinbeisser, H.3    Geissert, D.4    Gont, L.K.5    De Robertis, E.M.6
  • 93
    • 0028270311 scopus 로고
    • Follistatin, an antagonist of activin, is expressed in the spemann organizer and displays direct neuralizing activity
    • 91 Hemmati-Brivanlou A., Kelly O. G. and Melton D. A. (1994) Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity. Cell 77: 283-295
    • (1994) Cell , vol.77 , pp. 283-295
    • Hemmati-Brivanlou, A.1    Kelly, O.G.2    Melton, D.A.3
  • 94
    • 0029775569 scopus 로고    scopus 로고
    • Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of spemann's organizer
    • 92 Bouwmeester T., Kim S., Sasai Y., Lu B. and De Robertis E. M. (1996) Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer. Nature 382: 595-601
    • (1996) Nature , vol.382 , pp. 595-601
    • Bouwmeester, T.1    Kim, S.2    Sasai, Y.3    Lu, B.4    De Robertis, E.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.