Inhibition of nitric oxide-induced nuclear localization of CAPON by NMDA receptor antagonist in cultured rat primary astrocytes

Neurochemistry International

Volumn 56, Issue 4, 2010, Pages 561-568

  Jiang, Jing ^a   Yan, Meijuan ^a   Lv, Qingshan ^b   Cheng, Chun ^b   Li, Xiaohong ^a   Guo, Zhiqin ^a   Tao, Tao ^b   Shen, Aiguo ^a  

^a NANTONG UNIVERSITY   (China)

^b NANTONG MEDICAL COLLEGE   (China)

Author keywords

Astrocyte; CAPON; Neuronal nitric oxide synthase; Nitric oxide; NMDA receptor

Indexed keywords

DIZOCILPINE; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NITROPRUSSIDE SODIUM;

ANIMAL CELL; ARTICLE; ASTROCYTE; CARBOXY TERMINAL SEQUENCE; CELL FUNCTION; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; GENE OVEREXPRESSION; IMMUNOCYTOCHEMISTRY; NEWBORN; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PDZ DOMAIN; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; BLOTTING, WESTERN; CELL NUCLEUS; CELLS, CULTURED; CULTURE MEDIA; CYTOPLASM; DIZOCILPINE MALEATE; EXCITATORY AMINO ACID ANTAGONISTS; GLIAL FIBRILLARY ACIDIC PROTEIN; IMMUNOHISTOCHEMISTRY; NITRIC OXIDE; NITRIC OXIDE DONORS; NITROPRUSSIDE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA;

RATTUS;

EID: 77249145335     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2009.12.019     Document Type: Article

References (52)

1. Bal-Price A., and Brown G.C. Inflammatory neurodegeneration mediated by nitric oxide from activated glia-inhibiting neuronal respiration, causing glutamate release and excitotoxicity. J. Neurosci. 21 (2001) 6480-6491
2. Brahmachari S., Fung Y.K., and Pahan K. Induction of glial fibrillary acidic protein expression in astrocytes by nitric oxide. J. Neurosci. 26 (2006) 4930-4939
3. Brimecombe J.C., Boeckman F.A., and Aizenman E. Functional consequences of NR2 subunit composition in single recombinant N-methyl-d-aspartate receptors. Proc. Natl. Acad. Sci. U.S.A. 94 (1997) 11019-11024
4. Brosnan C.F., Battistini L., Raine C.S., Dickson D.W., Casadevall A., and Lee S.C. Reactive nitrogen intermediates in human neuropathology: an overview. Dev. Neurosci. 16 (1994) 152-161
5. Chang K.C., Barth A.S., Sasano T., Kizana E., Kashiwakura Y., Zhang Y., et al. CAPON modulates cardiac repolarization via neuronal nitric oxide synthase signaling in the heart. Proc. Natl. Acad. Sci. U.S.A. 105 (2008) 4477-4482
6. Cheah J.H., Kim S.F., Hester L.D., Clancy K.W., Patterson III S.E., Papadopoulos V., et al. NMDA receptor-nitric oxide transmission mediates neuronal iron homeostasis via the GTPase Dexras1. Neuron 51 (2006) 431-440
7. Chen N., Luo T., and Raymond L.A. Subtype-dependence of NMDA receptor channel open probability. J. Neurosci. 19 (1999) 6844-6854
8. Christopherson K.S., Hillier B.J., Lim W.A., and Bredt D.S. PSD-95 assembles a ternary complex with the N-methyl-d-aspartic acid receptor and a bivalent neuronal NO synthase PDZ domain. J. Biol. Chem. 274 (1999) 27467-27473
9. Coyle J.T., Tsai G., and Goff D. Converging evidence of NMDA receptor hypofunction in the pathophysiology of schizophrenia. Ann. N.Y. Acad. Sci. 1003 (2003) 318-327
10. Dawson T.M., and Snyder S.H. Gases as biological messengers: nitric oxide and carbon monoxide in the brain. J. Neurosci. 14 (1994) 5147-5159
11. Dawson V.L., Kizushi V.M., Huang P.L., Snyder S.H., and Dawson T.M. Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice. J. Neurosci. 16 (1996) 2479-2487
12. Dingledine R., Borges K., Bowie D., and Traynelis S.F. The glutamate receptor ion channels. Pharmacol. Rev. 51 (1999) 7-61
13. Eastwood S.L. Does the CAPON gene confer susceptibility to schizophrenia?. PLoS Med. 2 (2005) e348
14. Eugenin E.A., King J.E., Nath A., Calderon T.M., Zukin R.S., Bennett M.V., et al. HIV-tat induces formation of an LRP-PSD-95-NMDAR-nNOS complex that promotes apoptosis in neurons and astrocytes. Proc. Natl. Acad. Sci. U.S.A. 104 (2007) 3438-3443
15. Fang M., Jaffrey S.R., Sawa A., Ye K., Luo X., and Snyder S.H. Dexras1: a G protein specifically coupled to neuronal nitric oxide synthase via CAPON. Neuron 28 (2000) 183-193
16. Giraldi-Guimaraes A., Batista C.M., Carneiro K., Tenorio F., Cavalcante L.A., and Mendez-Otero R. A critical survey on nitric oxide synthase expression and nitric oxide function in the retinotectal system. Brain Res. Rev. 56 (2007) 403-426
17. Hirsch D.B., Steiner J.P., Dawson T.M., Mammen A., Hayek E., and Snyder S.H. Neurotransmitter release regulated by nitric oxide in PC-12 cells and brain synaptosomes. Curr. Biol. 3 (1993) 749-754
18. Hoffmann H., Gremme T., Hatt H., and Gottmann K. Synaptic activity-dependent developmental regulation of NMDA receptor subunit expression in cultured neocortical neurons. J. Neurochem. 75 (2000) 1590-1599
19. Iadecola C., Zhang F., Xu S., Casey R., and Ross M.E. Inducible nitric oxide synthase gene expression in brain following cerebral ischemia. J. Cereb. Blood Flow Metab. 15 (1995) 378-384
20. Jaffrey S.R., Benfenati F., Snowman A.M., Czernik A.J., and Snyder S.H. Neuronal nitric-oxide synthase localization mediated by a ternary complex with synapsin and CAPON. Proc. Natl. Acad. Sci. U.S.A. 99 (2002) 3199-3204
21. Jaffrey S.R., Snowman A.M., Eliasson M.J., Cohen N.A., and Snyder S.H. CAPON: a protein associated with neuronal nitric oxide synthase that regulates its interactions with PSD95. Neuron 20 (1998) 115-124
22. Jeremy J.Y., Rowe D., Emsley A.M., and Newby A.C. Nitric oxide and the proliferation of vascular smooth muscle cells. Cardiovasc. Res. 43 (1999) 580-594
23. Kang Y.C., Kim P.K., Choi B.M., Chung H.T., Ha K.S., Kwon Y.G., et al. Regulation of programmed cell death in neuronal cells by nitric oxide. In Vivo 18 (2004) 367-376
24. Krebs C., Fernandes H.B., Sheldon C., Raymond L.A., and Baimbridge K.G. Functional NMDA receptor subtype 2B is expressed in astrocytes after ischemia in vivo and anoxia in vitro. J. Neurosci. 23 (2003) 3364-3372
25. Krumenacker J.S., Hanafy K.A., and Murad F. Regulation of nitric oxide and soluble guanylyl cyclase. Brain Res. Bull. 62 (2004) 505-515
26. Lalo U., Pankratov Y., Kirchhoff F., North R.A., and Verkhratsky A. NMDA receptors mediate neuron-to-glia signaling in mouse cortical astrocytes. J. Neurosci. 26 (2006) 2673-2683
27. Lee S.Y., Kim H.J., Lee W.J., Joo S.H., Jeon S.J., Kim J.W., et al. Differential regulation of matrix metalloproteinase-9 and tissue plasminogen activator activity by the cyclic-AMP system in lipopolysaccharide-stimulated rat primary astrocytes. Neurochem. Res. 33 (2008) 2324-2334
28. Loesch A., Belai A., and Burnstock G. An ultrastructural study of NADPH-diaphorase and nitric oxide synthase in the perivascular nerves and vascular endothelium of the rat basilar artery. J. Neurocytol. 23 (1994) 49-59
29. Lynch D.R., and Guttmann R.P. Excitotoxicity: perspectives based on N-methyl-d-aspartate receptor subtypes. J. Pharmacol. Exp. Ther. 300 (2002) 717-723
30. Ma L., Morita I., and Murota S. Presence of constitutive type nitric oxide synthase in cultured astrocytes isolated from rat cerebra. Neurosci. Lett. 174 (1994) 123-126
31. Marzetti F., Pezzuto R.W., and Ducci M. Multiple stage cervical laryngotracheal reconstruction after trauma with extensive tissue loss. Acta Otorhinolaryngol. Ital. 17 (1997) 190-195
32. Mitrovic A.D., and Johnston G.A. Regional differences in the inhibition of l-glutamate and l-aspartate sodium-dependent high affinity uptake systems in rat CNS synaptosomes by l-trans-pyrrolidine-2,4-dicarboxylate, threo-3-hydroxy-d-aspartate and d-aspartate. Neurochem. Int. 24 (1994) 583-588
33. Murphy S., Simmons M.L., Agullo L., Garcia A., Feinstein D.L., Galea E., et al. Synthesis of nitric oxide in CNS glial cells. Trends Neurosci. 16 (1993) 323-328
34. Oliveira R.M., Guimaraes F.S., and Deakin J.F. Expression of neuronal nitric oxide synthase in the hippocampal formation in affective disorders. Braz. J. Med. Biol. Res. 41 (2008) 333-341
35. Perry V.H. The influence of systemic inflammation on inflammation in the brain: implications for chronic neurodegenerative disease. Brain Behav. Immun. 18 (2004) 407-413
36. Petralia R.S., Wang Y.X., and Wenthold R.J. The NMDA receptor subunits NR2A and NR2B show histological and ultrastructural localization patterns similar to those of NR1. J. Neurosci. 14 (1994) 6102-6120
37. Rameau G.A., Chiu L.Y., and Ziff E.B. NMDA receptor regulation of nNOS phosphorylation and induction of neuron death. Neurobiol. Aging 24 (2003) 1123-1133
38. Ryu J.S., Shin C.Y., Yang S.J., Lee T.S., La H.O., Song H.J., et al. NMDA receptor and NO mediate ET-1-induced behavioral and cardiovascular effects in periaqueductal gray matter of rats. Arch. Pharm. Res. 24 (2001) 64-68
39. Samdani A.F., Newcamp C., Resink A., Facchinetti F., Hoffman B.E., Dawson V.L., et al. Differential susceptibility to neurotoxicity mediated by neurotrophins and neuronal nitric oxide synthase. J. Neurosci. 17 (1997) 4633-4641
40. Scherzer C.R., Landwehrmeyer G.B., Kerner J.A., Counihan T.J., Kosinski C.M., Standaert D.G., et al. Expression of N-methyl-d-aspartate receptor subunit mRNAs in the human brain: hippocampus and cortex. J. Comp. Neurol. 390 (1998) 75-90
41. Schipke C.G., Ohlemeyer C., Matyash M., Nolte C., Kettenmann H., and Kirchhoff F. Astrocytes of the mouse neocortex express functional N-methyl-d-aspartate receptors. FASEB J. 15 (2001) 1270-1272
42. Sprengel R., Suchanek B., Amico C., Brusa R., Burnashev N., Rozov A., et al. Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo. Cell 92 (1998) 279-289
43. Sun L., Shipley M.T., and Lidow M.S. Expression of NR1, NR2A-D, and NR3 subunits of the NMDA receptor in the cerebral cortex and olfactory bulb of adult rat. Synapse 35 (2000) 212-221
44. Tegeder I., and Geisslinger G. Cardiovascular risk with cyclooxygenase inhibitors: general problem with substance specific differences?. Naunyn Schmiedebergs Arch. Pharmacol. 373 (2006) 1-17
45. Tomas M., Marin M.P., Portoles M., Megias L., Gomez-Lechon M.J., and Renau-Piqueras J. Ethanol affects calmodulin and the calmodulin-binding proteins neuronal nitric oxide synthase and alphaII-spectrin (alpha-fodrin) in the nucleus of growing and differentiated rat astrocytes in primary culture. Toxicol. In Vitro 21 (2007) 1039-1049
46. Varney M.A., Jachec C., Deal C., Hess S.D., Daggett L.P., Skvoretz R., et al. Stable expression and characterization of recombinant human heteromeric N-methyl-d-aspartate receptor subtypes NMDAR1A/2A and NMDAR1A/2B in mammalian cells. J. Pharmacol. Exp. Ther. 279 (1996) 367-378
47. Vincent S.R. Nitric oxide: a radical neurotransmitter in the central nervous system. Prog. Neurobiol. 42 (1994) 129-160
48. Vincent V.A., De Groot C.J., Lucassen P.J., Portegies P., Troost D., Tilders F.J., et al. Nitric oxide synthase expression and apoptotic cell death in brains of AIDS and AIDS dementia patients. AIDS 13 (1999) 317-326
49. Wang T., Wang B.R., Zhao H.Z., Kuang F., Fan J., Duan X.L., et al. Lipopolysaccharide up-regulates IL-6R alpha expression in cultured leptomeningeal cells via activation of ERK1/2 pathway. Neurochem. Res. 33 9 (2008) 1901-1910
50. Watkins J., and Collingridge G. Phenylglycine derivatives as antagonists of metabotropic glutamate receptors. Trends Pharmacol. Sci. 15 9 (1994) 333-342
51. Xu B., Wratten N., Charych E.I., Buyske S., Firestein B.L., and Brzustowicz L.M. Increased expression in dorsolateral prefrontal cortex of CAPON in schizophrenia and bipolar disorder. PLoS Med. 2 10 (2005) e263
52. Yuan Z., Liu B., Yuan L., Zhang Y., Dong X., and Lu J. Evidence of nuclear localization of neuronal nitric oxide synthase in cultured astrocytes of rats. Life Sci. 74 26 (2004) 3199-3209