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Volumn 5, Issue 3, 2010, Pages 415-419

Lectin-based drug design: Combined strategy to identify lead compounds using STD NMR spectroscopy, solid-phase assays and cell binding for a plant toxin model

(7) Ribeiro, João P a Andrá, Sabine b Cañada, F Javier a Gabius, Hans Joachim b Butera, Paola c Alves, Ricardo José c Jiménez Barbero, Jesffls a

a CENTRO DE INVESTIGACIONES BIOLÓGICAS (Spain)

b UNIVERSITY OF MUNICH (Germany)

c FEDERAL UNIVERSITY OF MINAS GERAIS (Brazil)

Author keywords

Antitumor agents; Drug design; Lectins; Molecular recognition; NMR

Indexed keywords

4 NITROGEN DIOXIDE PHENYLLACTOSIDE; CARBOHYDRATE DERIVATIVE; GALACTOSE OLIGOSACCHARIDE; GLYCAN; GLYCOPROTEIN; LACTOSE; LACTOSIDE; LECTIN; LIGAND; NITROGEN DIOXIDE; PLANT TOXIN; UNCLASSIFIED DRUG; VISCUMIN;

ARTICLE; BINDING AFFINITY; CELL ASSAY; CELL TYPE; CONTROLLED STUDY; DRUG DESIGN; DRUG POTENCY; HUMAN; HUMAN CELL; LECTIN BINDING; LIGAND BINDING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; SATURATION TRANSFER DIFFERENCE NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SCREENING; SOLID;

CELL LINE, TUMOR; CELL MEMBRANE; DRUG DESIGN; GLYCOPROTEINS; HUMANS; LACTOSE; LECTINS; LIGANDS; MODELS, BIOLOGICAL; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PLANT PROTEINS; PROTEIN BINDING; RIBOSOME INACTIVATING PROTEINS, TYPE 2; TOXINS, BIOLOGICAL; VISCUM ALBUM;

EID: 77249140580 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.200900476 Document Type: Article

Times cited : (31)

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