Monomer/dimer equilibrium of the AB-type lectin from mistletoe enables combination of toxin/agglutinin activities in one protein: Analysis of native and citraconylated proteins by ultracentrifugation/gel filtration and cell biological consequences of dimer destabilization

Glycobiology

Volumn 15, Issue 12, 2005, Pages 1386-1395

  Jiménez, Marta ^a   Sáiz, José L ^a   André, Sabine ^b   Gabius, Hans J ^b   Solís, Dolores ^a  

^a INSTITUTO DE QUÍMICA FÍSICA ROCASOLANO   (Spain)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

Agglutinin; Cytotoxicity; Lectin; Mistetoe; Ribosome inactivating protein

Indexed keywords

DIMER; MONOMER; PLANT LECTIN; PLANT TOXIN; RICIN; UNCLASSIFIED DRUG; VISCUMIN;

ANTIGEN ANTIBODY REACTION; ARTICLE; CALCULATION; CONTROLLED STUDY; CYTOLOGY; CYTOTOXICITY; EQUILIBRIUM CONSTANT; FAST PROTEIN LIQUID CHROMATOGRAPHY; FLUORESCENCE ACTIVATED CELL SORTING; GEL FILTRATION CHROMATOGRAPHY; GROWTH INHIBITION; HUMAN; HUMAN CELL; MITOGENICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; RICINUS COMMUNIS; SEDIMENTATION; ULTRACENTRIFUGATION; VISCUM ALBUM;

AGGLUTININS; ANIMALS; CELL LINE; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMATOGRAPHY, GEL; DIMERIZATION; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; HUMANS; LECTINS; LYMPHATIC METASTASIS; MACROMOLECULAR SUBSTANCES; MICE; MISTLETOE; MOLECULAR CONFORMATION; NIH 3T3 CELLS; PLANT PREPARATIONS; PLANT PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; RICINUS; TIME FACTORS; TOXINS, BIOLOGICAL; ULTRACENTRIFUGATION;

RICINUS COMMUNIS; VISCUM ALBUM;

EID: 28444497752     PISSN: 09596658     EISSN: 14602423     Source Type: Journal    
DOI: 10.1093/glycob/cwj020     Document Type: Article

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