α-O-linked glycopeptide mimetics: Synthesis, conformation analysis, and interactions with viscumin, a galactoside-binding model lectin

Chemistry - A European Journal

Volumn 15, Issue 40, 2009, Pages 10423-10431

  Jiménez Barbero, Jesús ^a   Dragoni, Elisa ^b,c   Venturis, Chiara ^a,b,c   Nannucci, Federico ^b   Ardá, Ana ^a   Fontanella, Marco ^a   André, Sabine ^d   Cañada, Francisco Javier ^a   Gabius, Hans Joachim ^d   Nativi, Cristina ^b,c  

^a CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^b Dipartimento di Chimica Organica   (Italy)

^c UNIVERSITY OF FLORENCE   (Italy)

^d UNIVERSITY OF MUNICH   (Germany)

Author keywords

Carbohydrates; Drug design; Glycoproteins; Lectins; Molecular modeling; NMR spectroscopy

Indexed keywords

ANOMERICS; BINDING MODELS; CHAIR CONFORMATIONS; CONFORMATION ANALYSIS; CONFORMATIONAL PROPERTIES; DIASTEREOSELECTIVE; DRUG DESIGN; EXPERIMENTAL TECHNIQUES; GALACTOSYLATION; GLYCOPEPTIDES; HETERODIENES; LECTINS; MIMETICS; MOLECULAR DOCKING; NMR SPECTROSCOPY; O-GLYCANS; O-LINKED; PLANT TOXINS; PYRANOSE; SYNTHETIC ROUTES;

CARBOHYDRATES; GLYCOPROTEINS; MOLECULAR MODELING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLYSACCHARIDES; PROTEINS; SCAFFOLDS; SILANES; SYNTHESIS (CHEMICAL);

NUCLEAR MAGNETIC RESONANCE;

GLYCOPEPTIDE; MISTLETOE LECTIN I; RIBOSOME INACTIVATING PROTEIN 2; TOXIN;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DESIGN; ISOLATION AND PURIFICATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN CONFORMATION; STEREOISOMERISM;

DRUG DESIGN; GLYCOPEPTIDES; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEIN CONFORMATION; RIBOSOME INACTIVATING PROTEINS, TYPE 2; STEREOISOMERISM; TOXINS, BIOLOGICAL;

EID: 70349921475     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.200901077     Document Type: Article

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