-
1
-
-
0032101546
-
Clinical significance of cytogenetic abnormalities in adult acute lymphoblastic leukemia
-
Faderl S, Kantarjian HM, Talpaz M, et al. Clinical significance of cytogenetic abnormalities in adult acute lymphoblastic leukemia. Blood 1998;9:3995-4019. (Pubitemid 28261960)
-
(1998)
Blood
, vol.91
, Issue.11
, pp. 3995-4019
-
-
Faderl, S.1
Kantarjian, H.M.2
Talpaz, M.3
Estrov, Z.4
-
2
-
-
33646168564
-
Management of acute lymphoblastic leukemia in older patients
-
Larson RA. Management of acute lymphoblastic leukemia in older patients. Semin Hematol 2006;43:126-133.
-
(2006)
Semin Hematol
, vol.43
, pp. 126-133
-
-
Larson, R.A.1
-
3
-
-
0025348013
-
Tyrosine kinase activity and transformation potency of bcr-abl oncogene products
-
Lugo TG, Pendergast AM, Muller AJ, Witte ON. Tyrosine kinase activity and transformation potency of bcr-abl oncogene products. Science 1990;247):1079-1082.
-
(1990)
Science
, vol.247
, pp. 1079-1082
-
-
Lugo, T.G.1
Pendergast, A.M.2
Muller, A.J.3
Witte, O.N.4
-
4
-
-
0033954540
-
Outcome of Philadelphia chromosome-positive adult acute lymphoblastic leukemia
-
Faderl S, Kantarjian HM, Thomas DA, et al. Outcome of Philadelphia chromosome-positive adult acute lymphoblastic leukemia. Leuk Lymphoma 2000;36:263-273.
-
(2000)
Leuk Lymphoma
, vol.36
, pp. 263-273
-
-
Faderl, S.1
Kantarjian, H.M.2
Thomas, D.A.3
-
5
-
-
0035093711
-
Philadelphia chromosome-positive acute lymphocytic leukemia
-
Radich JP. Philadelphia chromosome-positive acute lymphocytic leukemia. Hematol Oncol Clin North Am 2001;15:21-36.
-
(2001)
Hematol Oncol Clin North Am
, vol.15
, pp. 21-36
-
-
Radich, J.P.1
-
6
-
-
0036786909
-
Outcome of treatment in adults with Philadelphia chromosome-positive acute lymphoblastic leukemia-results of the prospective multicenter LALA-94 trial
-
Dombret H, Gabert J, Boiron JM, et al. Outcome of treatment in adults with Philadelphia chromosome-positive acute lymphoblastic leukemia-results of the prospective multicenter LALA-94 trial. Blood 2002;100:2357-2366.
-
(2002)
Blood
, vol.100
, pp. 2357-2366
-
-
Dombret, H.1
Gabert, J.2
Boiron, J.M.3
-
7
-
-
0029947186
-
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
-
Druker BJ, Tamura S, Buchdunger E, et al. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat Med 1996;2:561-566.
-
(1996)
Nat Med
, vol.2
, pp. 561-566
-
-
Druker, B.J.1
Tamura, S.2
Buchdunger, E.3
-
8
-
-
0034665903
-
CGP57148B (STI-571) induces differentiation and apoptosis and sensitizes Bcr-Ablpositive human leukemia cells to apoptosis due to anti leukemic drugs
-
Fang G, Kim CN, Perkins CL, et al. CGP57148B (STI-571) induces differentiation and apoptosis and sensitizes Bcr-Ablpositive human leukemia cells to apoptosis due to anti leukemic drugs. Blood 2000;96:2246-2253.
-
(2000)
Blood
, vol.96
, pp. 2246-2253
-
-
Fang, G.1
Kim, C.N.2
Perkins, C.L.3
-
9
-
-
15444350807
-
Selective inhibition of cell proliferation and BCR-ABL phosphorylation in acute lymphoblastic leukemia cells expressing Mr 190,000 BCR-ABL protein by a tyrosine kinase inhibitor (CGP-57148)
-
Beran M, Cao X, Estrov Z, et al. Selective inhibition of cell proliferation and BCR-ABL phosphorylation in acute lymphoblastic leukemia cells expressing Mr 190,000 BCR-ABL protein by a tyrosine kinase inhibitor (CGP-57148). Clin Cancer Res 1998;4:1661-1672.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 1661-1672
-
-
Beran, M.1
Cao, X.2
Estrov, Z.3
-
10
-
-
0037222235
-
Imatinib mesylate therapy in newly diagnosed patients with Philadelphia chromosome-positive chronic myelogenous leukemia: High incidence of early complete and major cytogenetic responses
-
DOI 10.1182/blood-2002-02-0545
-
Kantarjian HM, Cortes JE, O'Brien S, et al. Imatinib mesylate therapy in newly diagnosed patients with Philadelphia chromosome-positive chronic myelogenous leukemia: high incidence of early complete and major cytogenetic responses. Blood 2003;101:97-100. (Pubitemid 36025893)
-
(2003)
Blood
, vol.101
, Issue.1
, pp. 97-100
-
-
Kantarjian, H.M.1
Cortes, J.E.2
O'Brien, S.3
Giles, F.4
Garcia-Manero, G.5
Faderl, S.6
Thomas, D.7
Jeha, S.8
Rios, M.B.9
Letvak, L.10
Bochinski, K.11
Arlinghaus, R.12
Talpaz, M.13
-
11
-
-
0035810142
-
Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
-
Druker BJ, Sawyers CL, Kantarjian H, et al. Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N Engl J Med 2001;344:1038-1042.
-
(2001)
N Engl J Med
, vol.344
, pp. 1038-1042
-
-
Druker, B.J.1
Sawyers, C.L.2
Kantarjian, H.3
-
12
-
-
0037186915
-
Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia
-
Kantarjian H, Sawyers C, Hochhaus A, et al. Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia. N Engl J Med 2002;346: 645-652.
-
(2002)
N Engl J Med
, vol.346
, pp. 645-652
-
-
Kantarjian, H.1
Sawyers, C.2
Hochhaus, A.3
-
13
-
-
0037085785
-
Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: Results of a phase 2 study
-
DOI 10.1182/blood.V99.6.1928
-
Talpaz M, Silver RT, Druker BJ, et al. Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: results of a phase 2 study. Blood 2002;99:1928-1937. (Pubitemid 34525471)
-
(2002)
Blood
, vol.99
, Issue.6
, pp. 1928-1937
-
-
Talpaz, M.1
Silver, R.T.2
Druker, B.J.3
Goldman, J.M.4
Gambacorti-Passerini, C.5
Guilhot, F.6
Schiffer, C.A.7
Fischer, T.8
Deininger, M.W.N.9
Lennard, A.L.10
Hochhaus, A.11
Ottmann, O.G.12
Gratwohl, A.13
Baccarani, M.14
Stone, R.15
Tura, S.16
Mahon, F.-X.17
Fernandes-Reese, S.18
Gathmann, I.19
Capdeville, R.20
Kantarjian, H.M.21
Sawyers, C.L.22
more..
-
14
-
-
0037093092
-
Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: Results of a phase II study
-
DOI 10.1182/blood.V99.10.3530
-
Sawyers CL, Hochhaus A, Feldman E, et al. Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: results of a phase II study. Blood 2002;99:3530-3539. (Pubitemid 34534519)
-
(2002)
Blood
, vol.99
, Issue.10
, pp. 3530-3539
-
-
Sawyers, C.L.1
Hochhaus, A.2
Feldman, E.3
Goldman, J.M.4
Miller, C.B.5
Ottmann, O.G.6
Schiffer, C.A.7
Talpaz, M.8
Guilhot, F.9
Deininger, M.W.N.10
Fischer, T.11
O'Brien, S.G.12
Stone, R.M.13
Gambacorti-Passerini, C.B.14
Russell, N.H.15
Reiffers, J.J.16
Shea, T.C.17
Chapuis, B.18
Coutre, S.19
Tura, S.20
Morra, E.21
Larson, R.A.22
Saven, A.23
Peschel, C.24
Gratwohl, A.25
Mandelli, F.26
Ben-Am, M.27
Gathmann, I.28
Capdeville, R.29
Paquette, R.L.30
Druker, B.J.31
more..
-
15
-
-
0035992318
-
Treatment of Philadelphia chromosome-positive, accelerated-phase chronic myelogenous leukemia with imatinib mesylate
-
Kantarjian HM, O'Brien S, Cortes JE, et al. Treatment of Philadelphia chromosome-positive, accelerated-phase chronic myelogenous leukemia with imatinib mesylate. Clin Cancer Res 2002;8:2167-2176. (Pubitemid 34753587)
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.7
, pp. 2167-2176
-
-
Kantarjian, H.M.1
O'Brien, S.2
Cortes, J.E.3
Smith, T.L.4
Rios, M.B.5
Shan, J.6
Yang, Y.7
Giles, F.J.8
Thomas, D.A.9
Faderl, S.10
Garcia-Manero, G.11
Jeha, S.12
Wierda, W.13
Issa, J.-P.J.14
Kornblau, S.M.15
Keating, M.16
Resta, D.17
Capdeville, R.18
Talpaz, M.19
-
16
-
-
0037105560
-
A phase 2 study of imatinib in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoid leukemias
-
Ottmann OG, Druker BJ, Sawyers CL, et al. A phase 2 study of imatinib in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoid leukemias. Blood 2002;100:1965-1971.
-
(2002)
Blood
, vol.100
, pp. 1965-1971
-
-
Ottmann, O.G.1
Druker, B.J.2
Sawyers, C.L.3
-
17
-
-
0036940238
-
Therapy with imatinib mesylate (Glivec) preceding allogeneic stem cell transplantation (SCT) in relapsed or refractory Philadelphiapositive acute lymphoblastic leukemia (Ph+ALL)
-
Wassmann B, Pfeifer H, Scheuring U, et al. Therapy with imatinib mesylate (Glivec) preceding allogeneic stem cell transplantation (SCT) in relapsed or refractory Philadelphiapositive acute lymphoblastic leukemia (Ph+ALL). Leukemia 2002;16:2358-2365.
-
(2002)
Leukemia
, vol.16
, pp. 2358-2365
-
-
Wassmann, B.1
Pfeifer, H.2
Scheuring, U.3
-
18
-
-
2942567555
-
Treatment of Philadelphia chromosome-positive acute lymphocytic leukemia with hyper-CVAD and imatinib mesylate
-
DOI 10.1182/blood-2003-08-2958
-
Thomas DA, Faderl S, Cortes J, et al. Treatment of Philadelphia chromosome-positive acute lymphocytic leukemia with hyper-CVAD and imatinib mesylate. Blood 2004;103:4396-4407. (Pubitemid 38745962)
-
(2004)
Blood
, vol.103
, Issue.12
, pp. 4396-4407
-
-
Thomas, D.A.1
Faderl, S.2
Cortes, J.3
O'Brien, S.4
Giles, F.J.5
Kornblau, S.M.6
Garcia-Manero, G.7
Keating, M.J.8
Andreeff, M.9
Jeha, S.10
Beran, M.11
Verstovsek, S.12
Pierce, S.13
Letvak, L.14
Salvado, A.15
Champlin, R.16
Talpaz, M.17
Kantarjian, H.18
-
19
-
-
26944439774
-
Clinical effect of imatinib added to intensive combination chemotherapy for newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia
-
Lee KH, Lee JH, Choi SJ, et al. Clinical effect of imatinib added to intensive combination chemotherapy for newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia. Leukemia 2005;19:1509-1516.
-
(2005)
Leukemia
, vol.19
, pp. 1509-1516
-
-
Lee, K.H.1
Lee, J.H.2
Choi, S.J.3
-
20
-
-
33644845774
-
High complete remission rate and promising outcome by combination of imatinib and chemotherapy for newly diagnosed BCR-ABL positive acute lymphoblastic leukemia: A phase II study by the Japan Adult Leukemia Study Group
-
Yanada M, Takeuchi J, Sugiura I, et al. High complete remission rate and promising outcome by combination of imatinib and chemotherapy for newly diagnosed BCR-ABL positive acute lymphoblastic leukemia: a phase II study by the Japan Adult Leukemia Study Group. J Clin Oncol 2006;24:460-466.
-
(2006)
J Clin Oncol
, vol.24
, pp. 460-466
-
-
Yanada, M.1
Takeuchi, J.2
Sugiura, I.3
-
21
-
-
33846916856
-
Imatinib combined with induction or consolidation chemotherapy in patients with de novo Philadelphia chromosome-positive acute lymphoblastic leukemia: Results of the GRAAPH-2003 study
-
de Labarthe A, Rousselot P, Huguet-Rigal F, et al. Imatinib combined with induction or consolidation chemotherapy in patients with de novo Philadelphia chromosome-positive acute lymphoblastic leukemia: results of the GRAAPH-2003 study. Blood 2007;109:1408-1413.
-
(2007)
Blood
, vol.109
, pp. 1408-1413
-
-
De Labarthe, A.1
Rousselot, P.2
Huguet-Rigal, F.3
-
22
-
-
34247359952
-
Imatinib plus steroids induces complete remissions and prolonged survival in elderly Philadelphia chromosome-positive patients with acute lymphoblastic leukemia without additional chemotherapy: Results of the Gruppo Italiano Malattie Ematologiche dell'Adulto (GIMEMA) LAL0201-B protocol
-
Vignetti M, Fazi P, Cimino G, et al. Imatinib plus steroids induces complete remissions and prolonged survival in elderly Philadelphia chromosome-positive patients with acute lymphoblastic leukemia without additional chemotherapy: results of the Gruppo Italiano Malattie Ematologiche dell'Adulto (GIMEMA) LAL0201-B protocol. Blood 2007;109:3676-3678.
-
(2007)
Blood
, vol.109
, pp. 3676-3678
-
-
Vignetti, M.1
Fazi, P.2
Cimino, G.3
-
23
-
-
33750470841
-
Imatinib combined chemotherapy for Philadelphia chromosome-positive acute lymphoblastic leukemia: Major challenges in current practice
-
Yanada M, Naoe T. Imatinib combined chemotherapy for Philadelphia chromosome-positive acute lymphoblastic leukemia: major challenges in current practice. Leuk Lymphoma 2006;47:1747-1753.
-
(2006)
Leuk Lymphoma
, vol.47
, pp. 1747-1753
-
-
Yanada, M.1
Naoe, T.2
-
24
-
-
9444289883
-
Combination of intensive chemotherapy and imatinib can rapidly induce highquality complete remission for a majority of patients with newly diagnosed BCR-ABL-positive acute lymphoblastic leukemia
-
Towatari M, Yanada M, Usui N, et al. Combination of intensive chemotherapy and imatinib can rapidly induce highquality complete remission for a majority of patients with newly diagnosed BCR-ABL-positive acute lymphoblastic leukemia. Blood 2004;104:3507-3512.
-
(2004)
Blood
, vol.104
, pp. 3507-3512
-
-
Towatari, M.1
Yanada, M.2
Usui, N.3
-
25
-
-
33645394581
-
The role of BCR/ABL isoforms in the presentation and outcome of patients with Philadelphia-positive acute lymphoblastic leukemia: A seven-year update of the GIMEMA 0496 trial
-
Giuseppe Cimino, Fabrizio Pane, Loredana Elia, et al. The role of BCR/ABL isoforms in the presentation and outcome of patients with Philadelphia-positive acute lymphoblastic leukemia: a seven-year update of the GIMEMA 0496 trial. Haematologica 2006;91:377-380.
-
(2006)
Haematologica
, vol.91
, pp. 377-380
-
-
Cimino, G.1
Pane, F.2
Elia, L.3
-
26
-
-
0033964380
-
Results of treatment with hyper-CVAD, a dose-intensive regimen, in adult acute lymphocytic leukemia
-
KantarjianHM, O'Brien S,SmithTL, et al. Results of treatment with hyper-CVAD, a dose-intensive regimen, in adult acute lymphocytic leukemia. J Clin Oncol 2000;18:547-561.
-
(2000)
J Clin Oncol
, vol.18
, pp. 547-561
-
-
O'Brien Ssmithtl, K.1
-
27
-
-
0036493694
-
Leading prognostic relevance of the BCR-ABL translocation in adult acute B-lineage lymphoblastic leukemia: A prospective study of the German Multicenter Trial Group and confirmed polymerase chain reaction analysis
-
Gleissner B, Gokbuget N, Bartram CR, et al. Leading prognostic relevance of the BCR-ABL translocation in adult acute B-lineage lymphoblastic leukemia: a prospective study of the German Multicenter Trial Group and confirmed polymerase chain reaction analysis. Blood 2002;99:1536-1543.
-
(2002)
Blood
, vol.99
, pp. 1536-1543
-
-
Gleissner, B.1
Gokbuget, N.2
Bartram, C.R.3
-
28
-
-
0034611661
-
Outcome of treatment in children with Philadelphia chromosome-positive acute lymphoblastic leukemia
-
Arico M, ValsecchiMG,Camitta B, et al. Outcome of treatment in children with Philadelphia chromosome-positive acute lymphoblastic leukemia. N Engl J Med 2000;342:998-1006.
-
(2000)
N Engl J Med
, vol.342
, pp. 998-1006
-
-
Arico, M.1
Valsecchimgcamitta, B.2
-
29
-
-
0035869381
-
Unrelatedmarrow transplantation for adult patients with poor-risk acute lymphoblastic leukemia: Strong graft-versus-leukemia effect and risk factors determining outcome
-
Cornelissen JJ, Carston M, Kollman C, et al.Unrelatedmarrow transplantation for adult patients with poor-risk acute lymphoblastic leukemia: strong graft-versus-leukemia effect and risk factors determining outcome. Blood 2001;97:1572-1577.
-
(2001)
Blood
, vol.97
, pp. 1572-1577
-
-
Cornelissen, J.J.1
Carston, M.2
Kollman, C.3
-
30
-
-
33749022243
-
Alternative donor transplants for adult acute lymphoblastic leukaemia: A comparison of the three major options
-
Marks DI, Aversa F, Lazarus HM. Alternative donor transplants for adult acute lymphoblastic leukaemia: a comparison of the three major options. Bone Marrow Transplant 2006;38: 467-475.
-
(2006)
Bone Marrow Transplant
, vol.38
, pp. 467-475
-
-
Marks, D.I.1
Aversa, F.2
Lazarus, H.M.3
-
31
-
-
9244256765
-
Outcomes after transplantation of cord blood or bone marrow from unrelated donors in adults with leukemia
-
Laughlin MJ, Eapen M, Rubinstein P, et al. Outcomes after transplantation of cord blood or bone marrow from unrelated donors in adults with leukemia. N Engl J Med 2004;351:2265-2275.
-
(2004)
N Engl J Med
, vol.351
, pp. 2265-2275
-
-
Laughlin, M.J.1
Eapen, M.2
Rubinstein, P.3
-
32
-
-
59549085066
-
Allo-hematopoietic cell transplantation for Ph chromosome-positive ALL: Impact of imatinib on relapse and survival
-
Burke MJ, Trotz B, Luo X, et al. Allo-hematopoietic cell transplantation for Ph chromosome-positive ALL: impact of imatinib on relapse and survival. Bone Marrow Transplant 2009;43:107-113.
-
(2009)
Bone Marrow Transplant
, vol.43
, pp. 107-113
-
-
Burke, M.J.1
Trotz, B.2
Luo, X.3
-
33
-
-
33846925617
-
The effects of imatinib mesylate treatment before allogeneic transplantation for chronic myeloid leukemia
-
Oehler VG, Gooley T, Snyder DS, et al. The effects of imatinib mesylate treatment before allogeneic transplantation for chronic myeloid leukemia. Blood 2007;109:1782-1789.
-
(2007)
Blood
, vol.109
, pp. 1782-1789
-
-
Oehler, V.G.1
Gooley, T.2
Snyder, D.S.3
-
34
-
-
18244407767
-
The effect of first-line imatinib interim therapy on the outcome of allogeneic stem cell transplantation in adults with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia
-
Lee S, Kim YJ, Min CK, et al. The effect of first-line imatinib interim therapy on the outcome of allogeneic stem cell transplantation in adults with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia. Blood 2005;105:3449-3457.
-
(2005)
Blood
, vol.105
, pp. 3449-3457
-
-
Lee, S.1
Kim, Y.J.2
Min, C.K.3
-
35
-
-
22144460555
-
Early molecular response to posttransplantation imatinib determines outcome in MRD+ Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL)
-
Wassmann B, Pfeifer H, Stadler M, et al. Early molecular response to posttransplantation imatinib determines outcome in MRD+ Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL). Blood 2005;106:458-463.
-
(2005)
Blood
, vol.106
, pp. 458-463
-
-
Wassmann, B.1
Pfeifer, H.2
Stadler, M.3
|