Evaluation of apoptotic and anti-apoptotic genes on efficacy of DNA vaccine encoding glycoprotein B of Herpes Simplex Virus type 1

Immunology Letters

Volumn 128, Issue 2, 2010, Pages 137-142

  Parsania, Masoud ^a,c   Bamdad, Taravat ^a   Hassan, Zuhair Mohammad ^a   Kheirandish, Maryam ^b   Pouriayevali, Mohammad Hassan ^a   Sari, Rohollah Dorostkar ^a   Jamali, Abbas ^a  

^a TARBIAT MODARES UNIVERSITY   (Iran)

^b IRANIAN BLOOD TRANSFUSION ORGANIZATION   (Iran)

^c ISLAMIC AZAD UNIVERSITY   (Iran)

Author keywords

Anti apoptosis; Apoptosis; DNA vaccine; HSV 1

Indexed keywords

DENDROSOME; DNA VACCINE; GAMMA INTERFERON; GLYCOPROTEIN B; IMMUNOGLOBULIN G; INTERLEUKIN 4; NANOPARTICLE; PLASMID DNA; PROTEIN BAX; PROTEIN BCL XL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY PRODUCTION; APOPTOSIS; ARTICLE; CELLULAR IMMUNITY; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; DNA IMMUNIZATION; DRUG SCREENING; HERPES SIMPLEX VIRUS 1; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNOASSAY; IN VITRO STUDY; LYMPHOCYTE PROLIFERATION; MALE; MONOTHERAPY; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; SPLEEN CELL; TH1 CELL; TH2 CELL;

ANIMALS; ANTIBODIES, VIRAL; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; IMMUNIZATION; INTERLEUKIN-4; LYMPHOCYTE ACTIVATION; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PLASMIDS; T-LYMPHOCYTES, CYTOTOXIC; TREATMENT OUTCOME; VACCINES, DNA; VIRAL ENVELOPE PROTEINS;

EID: 77249113684     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imlet.2009.12.014     Document Type: Article

References (36)

1. Bergmann-Leitner E.S., Leitner W.W. Danger, death and DNA vaccines. Microbes Infect 2004, 6:319-327.
2. Kinsey B.M., Marcelli M., Song L., Bhogal B.S., Ittmann M., Orson F.M. Enhancement of both cellular and humoral responses to genetic immunization by co-administration of an antigen-expressing plasmid and a plasmid encoding the pro-apoptotic protein Bax. J Gene Med 2004, 6:445-454.
3. Leitner W.W., Restifo N.P. DNA vaccines and apoptosis: to kill or not to kill? J Clin Invest 2003, 112:22-24.
4. Parsania M., Hassan Z.M., Bamdad T., et al. Pro-apoptotic gene enhances the immunogenicity of glycoprotein b gene of herpes simplex virus-1. Gene Ther Mol Biol 2008, 12:7-14.
5. Sasaki S., Amara R.R., Oran A.E., Smith J.M., Robinson H.L. Apoptosis-mediated enhancement of DNA-raised immune responses by mutant caspases. Nat Biotechnol 2001, 19:543-547.
6. Kim T.W., Hung C.F., Ling M., Juang J., Hardwik J.M. Enhancing DNA vaccine potency by coadministration of DNA encoding antiapoptotic proteins. J Clin Invest 2003, 112:109-117.
7. Kim D., Hoory T., Wu T.C., Hung C.F. Enhancing DNA vaccine potency by combining a strategy to prolong dendritic cell life and intracellular targeting strategies with a strategy to boost CD4+ T cell. Hum Gene Ther 2007, 18:1129-1139.
8. Kang T.H., Lee J.H., Noh K.H., et al. Enhancing dendritic cell vaccine potency by combining a BAK/BAX siRNA-mediated antiapoptotic strategy to prolong dendritic cell life with an intracellular strategy to target antigen to lysosomal compartments. Int J Cancer 2007, 120:1696-1703.
9. Cheng W.F., Chang M.C., Sun W.Z., et al. Connective tissue growth factor linked to the E7 tumor antigen generates potent antitumor immune responses mediated by an antiapoptotic mechanism. Gene Ther 2008, 15:1007-1016.
10. Huang B., Mao C.P., Peng S., He L., Hung C.F., Wu T.C. Intradermal administration of DNA vaccines combining a strategy to bypass antigen processing with a strategy to prolong dendritic cell survival enhances DNA vaccine potency. Vaccine 2007, 25:7824-7831.
11. Kim T.W., Hung C.F., Boyd D., Juang J., Kim J.W. Enhancing DNA vaccine potency by combining a strategy to prolong dendritic cell life with intracellular targeting strategies. J Immunol 2003, 171:2970-2976.
12. Bernstein D.I., Stanberry L.R. Herpes simplex virus vaccines. Vaccine 1999, 17:1681-1689.
13. Koelle D.M., Corey L. Recent progress in herpes simplex virus immunobiology and vaccine research. Clin Microbiol Rev 2003, 16:96-113.
14. Stanberry L.R., Spruance S.L., Cunningham A.L., et al. Glycoprotein-D-adjuvant vaccine to prevent genital herpes. N Engl J Med 2002, 347:1652-1661.
15. Flo J., Beatriz Perez A., Tisminetzky S., Baralle F. Superiority of intramuscular route and full length glycoprotein D for DNA vaccination against herpes simplex 2. Enhancement of protection by the co-delivery of the GM-CSF gene. Vaccine 2000, 18:3242-3253.
16. Sarbolouki M.N., Sadeghizadeh M., Yaghoobi M.M., Karami A., Lohrasbi T. Dendrosomes: a novel family of vehicles for transfection and therapy. J Chem Tech Biotech 2000, 75:919-922.
17. Balenga N.A., Zahedifard F., Weiss R., Sarbolouki M.N., Thalhamer J., Rafati S. Protective efficiency of dendrosomes as novel nano-sized adjuvants for DNA vaccination against birch pollen allergy. J Biotechnol 2006, 124:602-614.
18. Bamdad T., Roostaee M.H., Sadeghizadeh M., Mahboudi F., Kazemnejad A., Soleimanjahi H. Immunogenicity and protective effect of a DNA construct encoding certain neutralizing epitopes of herpes simplex virus type-1 glycoprotein B. Folia Biol (Praha) 2005, 51:109-113.
19. Leitner W.W., Hwang L.N., Bergmann-Leitner E.S., Finklstein S.E., Frank S., Restifo N.P. Apoptosis is essential for the increased efficacy of alphaviral replicase-based DNA vaccines. Vaccine 2004, 22:1537-1544.
20. Pachl C., Burke R.L., Stuve L.L., et al. Expression of cell-associated and secreted forms of herpes simplex virus type 1 glycoprotein gB in mammalian cells. J Virol 1987, 61:315-325.
21. Sin J.I., Kim J.J., Boyer J.D., Ciccarelli R.B., Higgins T.J., Weiner D.B. In vivo modulation of vaccine-induced immune responses toward a Th1 phenotype increases potency and vaccine effectiveness in a herpes simplex virus type 2 mouse model. J Virol 1999, 73:501-509.
22. Nass P.H., Elkins K.L., Weir J.P. Protective immunity against herpes simplex virus generated by DNA vaccination compared to natural infection. Vaccine 2001, 19:1538-1546.
23. Xiao S., Chen H., Fang L., et al. Comparison of immune responses and protective efficacy of suicidal DNA vaccine and conventional DNA vaccine encoding glycoprotein C of pseudorabies virus in mice. Vaccine 2004, 22:345-351.
24. Schmid I., Krall W.J., Uittenbogaart C.H., Braun J., Giorgi J.V. Dead cell discrimination with 7-amino-actinomycin D in combination with dual color immunofluorescence in single laser flow cytometry. Cytometry 1992, 13:204-208.
25. O'Brien M.C., Bolton W.E. Comparison of cell viability probes compatible with fixation and permeabilization for combined surface and intracellular staining in flow cytometry. Cytometry 1995, 19:243-255.
26. Koopman G., Reutelingsperger C.P., Kuijten G.A., Keehnen R.M., Pals S.T., van Oers M.H. Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood 1994, 84:1415-1420.
27. van Engeland M., Nieland L.J., Ramaekers F.C., Schutte B., Reutelingsperger C.P. Annexin V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure. Cytometry 1998, 31:1-9.
28. Vermes I., Haanen C., Steffens-Nakken H., Reutelingsperger C. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. J Immunol Methods 1995, 184:39-51.
29. Derby E., Reddy V., Kopp W., et al. Three-color flow cytometric assay for the study of the mechanisms of cell-mediated cytotoxicity. Immunol Lett 2001, 78:35-39.
30. LI A.F., Houng J., Henderson D., Escher A. Co-delivery of pro-apoptotic BAX vaccine recruits dendritic cells and promotes efficacy of autoimmune diabetes prevention in mice. Vaccine 2004, 22:1751-1763.
31. Nimal S., Thomas M.S., Heath A.W. Fusion of antigen to Fas-ligand in a DNA vaccine enhances immunogenicity. Vaccine 2007, 25:2306-2315.
32. Mester J.C., Twomey T.A., Tepe E.T., Bernstein D.I. Immunity induced by DNA immunization with Herpes simplex virus type 2 glycoproteins B and C. Vaccine 2000, 18:875-883.
33. Domingo C., Gadea I., Paredeiro M., Castilla C., Fernandez S. Immunological properties of a DNA plasmid encoding a chimeric protein of Herpes simplex virus type 2 glycoprotein B and glycoprotein D. Vaccine 2003, 21:3565-3574.
34. Balenga N.A., Zahedifard F., Weiss R., Sarbolouki M.N., Thalhamer J., Rafati S. Protective efficiency of dendrosomes as novel nano-sized adjuvants for DNA vaccination against birch pollen allergy. J Biotechnol 2006, 124(3):602-614.
35. Bergmann-Leitner E.S., Leitner W.W., Duncan E.H., Savranskaya T., Angov E. Molecular adjuvants for malaria DNA vaccines based on the modulation of host-cell apoptosis. Vaccine 2009, 27:5700-5708.
36. Kojima Y., Jounai N., Takeshita F., Nakazawa M., Okuda K., Watabe S., Xin K.Q., Okuda K. The degree of apoptosis as an immunostimulant for a DNA vaccine against HIV-1 infection. Vaccine 2007, 25:438-445.