Intradermal administration of DNA vaccines combining a strategy to bypass antigen processing with a strategy to prolong dendritic cell survival enhances DNA vaccine potency

Vaccine

Volumn 25, Issue 45, 2007, Pages 7824-7831

  Huang, Bruce ^a   Mao, Chih Ping ^a   Peng, Shiwen ^a   He, Liangmei ^a   Hung, Chien Fu ^a   Wu, T C ^a  

^a DEPARTMENT OF PATHOLOGY   (United States)

Author keywords

BclxL; Cancer immunotherapy; Dendritic cells; DNA vaccines; E6; Human papillomavirus 16 (HPV 16); Single chain trimer (SCT); Tumor treatment

Indexed keywords

BETA 2 MICROGLOBULIN; CD8 ANTIGEN; DNA VACCINE; EPITOPE; GAMMA INTERFERON; INHIBITOR OF APOPTOSIS PROTEIN; LUCIFERASE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PROTEIN BCL XL; PROTEIN E6;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTATION; ANTIGEN SPECIFICITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CD8+ T LYMPHOCYTE; CELL SURFACE; CELL SURVIVAL; CONTROLLED STUDY; DENDRITIC CELL; DNA IMMUNIZATION; DRUG POTENCY; FEMALE; HUMAN PAPILLOMAVIRUS TYPE 16; IMMUNE RESPONSE; IMMUNOGENICITY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

ANIMALS; CELL SURVIVAL; DENDRITIC CELLS; DRUG ADMINISTRATION ROUTES; EPITOPES; INJECTIONS, INTRADERMAL; MICE; MICE, INBRED C57BL; ONCOGENE PROTEINS, VIRAL; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS VACCINES; REPRESSOR PROTEINS; VACCINES, DNA;

EID: 35348894921     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2007.08.036     Document Type: Article

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