메뉴 건너뛰기




Volumn 219, Issue 1-2, 2010, Pages 64-74

Additive effects of combination treatment with anti-inflammatory and neuroprotective agents in experimental autoimmune encephalomyelitis

Author keywords

Cytokine; Estrogen; Experimental autoimmune encephalomyelitis; Interferon beta; Multiple sclerosis

Indexed keywords

BETA INTERFERON; ESTROGEN RECEPTOR BETA; GELATINASE B; INTERLEUKIN 10; INTERLEUKIN 17; NICOTINAMIDE ADENINE DINUCLEOTIDE; VERY LATE ACTIVATION ANTIGEN 4;

EID: 77249101481     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2009.11.018     Document Type: Article
Times cited : (11)

References (44)
  • 1
    • 0034485142 scopus 로고    scopus 로고
    • Estrogen receptor alpha in human breast cancer: occurrence and significance
    • Ali S., Coombes R.C. Estrogen receptor alpha in human breast cancer: occurrence and significance. J. Mammary Gland Biol. Neoplasia 2000, 5:271-281.
    • (2000) J. Mammary Gland Biol. Neoplasia , vol.5 , pp. 271-281
    • Ali, S.1    Coombes, R.C.2
  • 2
    • 0033017354 scopus 로고    scopus 로고
    • Immunologic therapy of multiple sclerosis
    • Arnason B.G.W. Immunologic therapy of multiple sclerosis. Annu. Rev. Med. 1999, 50:291-302.
    • (1999) Annu. Rev. Med. , vol.50 , pp. 291-302
    • Arnason, B.G.W.1
  • 3
    • 43049165460 scopus 로고    scopus 로고
    • Type 1 interferons cool the inflamed brain
    • Axtell R.C., Steinman L. Type 1 interferons cool the inflamed brain. Immunity 2008, 28:600-602.
    • (2008) Immunity , vol.28 , pp. 600-602
    • Axtell, R.C.1    Steinman, L.2
  • 4
    • 60549086393 scopus 로고    scopus 로고
    • Beta(1) integrins differentially control extravasation of inflammatory cell subsets into the CNS during autoimmunity
    • Bauer M., Brakebusch C., Coisne C., Sixt M., Wekerle H., Engelhardt B., Fassler R. beta(1) integrins differentially control extravasation of inflammatory cell subsets into the CNS during autoimmunity. Proc. Natl Acad. Sci. USA 2009, 106:1920-1925.
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 1920-1925
    • Bauer, M.1    Brakebusch, C.2    Coisne, C.3    Sixt, M.4    Wekerle, H.5    Engelhardt, B.6    Fassler, R.7
  • 5
    • 33747115709 scopus 로고    scopus 로고
    • Anti-inflammatory properties of Type I interferons
    • Billiau A. Anti-inflammatory properties of Type I interferons. Antiviral Res. 2006, 71:108-116.
    • (2006) Antiviral Res. , vol.71 , pp. 108-116
    • Billiau, A.1
  • 6
    • 0009435112 scopus 로고
    • The Vcam-1/Vla-4 pathway is involved in chronic lesion expression in multiple-sclerosis (MS)
    • Cannella B., Raine C.S. The Vcam-1/Vla-4 pathway is involved in chronic lesion expression in multiple-sclerosis (MS). J. Neuropathol. Exp. Neurol. 1993, 52:311-311.
    • (1993) J. Neuropathol. Exp. Neurol. , vol.52 , pp. 311-311
    • Cannella, B.1    Raine, C.S.2
  • 7
    • 10344255797 scopus 로고    scopus 로고
    • Interferon beta-1a in relapsing multiple sclerosis: four-year extension of the European IFNbeta-1a Dose-Comparison Study
    • Clanet M., Kappos L., Hartung H.P., Hohlfeld R. Interferon beta-1a in relapsing multiple sclerosis: four-year extension of the European IFNbeta-1a Dose-Comparison Study. Mult. Scler. 2004, 10:139-144.
    • (2004) Mult. Scler. , vol.10 , pp. 139-144
    • Clanet, M.1    Kappos, L.2    Hartung, H.P.3    Hohlfeld, R.4
  • 10
    • 77249158016 scopus 로고    scopus 로고
    • Differential roles of Th1 and Th17 CD4+ T cell subsets in the pathogenesis of EAE
    • Domingues H.S., Krishnamoorthy G., Lassmann H., Wekerle H. Differential roles of Th1 and Th17 CD4+ T cell subsets in the pathogenesis of EAE. J. Neuroimmunol. 2008, 203:238-239.
    • (2008) J. Neuroimmunol. , vol.203 , pp. 238-239
    • Domingues, H.S.1    Krishnamoorthy, G.2    Lassmann, H.3    Wekerle, H.4
  • 11
    • 44849090628 scopus 로고    scopus 로고
    • Estrogen receptor alpha, but not beta, is required for optimal dendritic cell differentiation and [corrected] CD40-induced cytokine production
    • Douin-Echinard V., Laffont S., Seillet C., Delpy L., Krust A., Chambon P., Gourdy P., Arnal J.F., Guery J.C. Estrogen receptor alpha, but not beta, is required for optimal dendritic cell differentiation and [corrected] CD40-induced cytokine production. J. Immunol. 2008, 180:3661-3669.
    • (2008) J. Immunol. , vol.180 , pp. 3661-3669
    • Douin-Echinard, V.1    Laffont, S.2    Seillet, C.3    Delpy, L.4    Krust, A.5    Chambon, P.6    Gourdy, P.7    Arnal, J.F.8    Guery, J.C.9
  • 12
    • 18844429202 scopus 로고    scopus 로고
    • Suppression of experimental autoimmune encephalomyelitis using estrogen receptor-selective ligands
    • Elloso M.M., Phiel K., Henderson R.A., Harris H.A., Adelman S.J. Suppression of experimental autoimmune encephalomyelitis using estrogen receptor-selective ligands. J. Endocrinol. 2005, 185:243-252.
    • (2005) J. Endocrinol. , vol.185 , pp. 243-252
    • Elloso, M.M.1    Phiel, K.2    Henderson, R.A.3    Harris, H.A.4    Adelman, S.J.5
  • 14
    • 77249143004 scopus 로고    scopus 로고
    • Estrogen receptor alpha-signaling in inflammatory leukocytes is dispensable for 17 beta-estradiol-mediated inhibition of experimental autoimmune encephalomyelitis
    • Garidou L., Laffont S., Douin V., Krust A., Chambon P., Guy J.C., Guery J.C. Estrogen receptor alpha-signaling in inflammatory leukocytes is dispensable for 17 beta-estradiol-mediated inhibition of experimental autoimmune encephalomyelitis. J. Neuroimmunol. 2004, 154:83-83.
    • (2004) J. Neuroimmunol. , vol.154 , pp. 83-83
    • Garidou, L.1    Laffont, S.2    Douin, V.3    Krust, A.4    Chambon, P.5    Guy, J.C.6    Guery, J.C.7
  • 15
    • 60049089535 scopus 로고    scopus 로고
    • Effect of natalizumab on clinical and radiological disease activity in multiple sclerosis: a retrospective analysis of the Natalizumab Safety and Efficacy in Relapsing-Remitting Multiple Sclerosis (AFFIRM) study
    • Havrdova E., Galetta S., Hutchinson M., Stefoski D., Bates D., Polman C.H., O'Connor P.W., Giovannoni G., Phillips J.T., Lublin F.D., Pace A., Kim R., Hyde R. Effect of natalizumab on clinical and radiological disease activity in multiple sclerosis: a retrospective analysis of the Natalizumab Safety and Efficacy in Relapsing-Remitting Multiple Sclerosis (AFFIRM) study. Lancet Neurol. 2009, 8:254-260.
    • (2009) Lancet Neurol. , vol.8 , pp. 254-260
    • Havrdova, E.1    Galetta, S.2    Hutchinson, M.3    Stefoski, D.4    Bates, D.5    Polman, C.H.6    O'Connor, P.W.7    Giovannoni, G.8    Phillips, J.T.9    Lublin, F.D.10    Pace, A.11    Kim, R.12    Hyde, R.13
  • 18
    • 0035464310 scopus 로고    scopus 로고
    • Enhancement of collagen-induced arthritis in female mice by estrogen receptor blockage
    • Jansson L., Holmdahl R. Enhancement of collagen-induced arthritis in female mice by estrogen receptor blockage. Arthritis Rheum. 2001, 44:2168-2175.
    • (2001) Arthritis Rheum. , vol.44 , pp. 2168-2175
    • Jansson, L.1    Holmdahl, R.2
  • 19
    • 0027991759 scopus 로고
    • Estrogen induces a potent suppression of experimental autoimmune encephalomyelitis and collagen-induced arthritis in mice
    • Jansson L., Olsson T., Holmdahl R. Estrogen induces a potent suppression of experimental autoimmune encephalomyelitis and collagen-induced arthritis in mice. J. Neuroimmunol. 1994, 53:203-207.
    • (1994) J. Neuroimmunol. , vol.53 , pp. 203-207
    • Jansson, L.1    Olsson, T.2    Holmdahl, R.3
  • 21
    • 0346366976 scopus 로고    scopus 로고
    • Estrogen receptor alpha mediates estrogen's immune protection in autoimmune disease
    • Liu H.B., Loo K.K., Palaszynski K., Ashouri J., Lubahn D.B., Voskuhl R.R. Estrogen receptor alpha mediates estrogen's immune protection in autoimmune disease. J. Immunol. 2003, 171:6936-6940.
    • (2003) J. Immunol. , vol.171 , pp. 6936-6940
    • Liu, H.B.1    Loo, K.K.2    Palaszynski, K.3    Ashouri, J.4    Lubahn, D.B.5    Voskuhl, R.R.6
  • 22
    • 0344838658 scopus 로고    scopus 로고
    • Estradiol enhances primary antigen-specific CD4 T cell responses and Th1 development in vivo. Essential role of estrogen receptor alpha expression in hematopoietic cells
    • Maret A., Coudert J.D., Garidou L., Foucras G., Gourdy P., Krust A., Dupont S., Chambon P., Druet P., Bayard F., Guery J.C. Estradiol enhances primary antigen-specific CD4 T cell responses and Th1 development in vivo. Essential role of estrogen receptor alpha expression in hematopoietic cells. Eur. J. Immunol. 2003, 33:512-521.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 512-521
    • Maret, A.1    Coudert, J.D.2    Garidou, L.3    Foucras, G.4    Gourdy, P.5    Krust, A.6    Dupont, S.7    Chambon, P.8    Druet, P.9    Bayard, F.10    Guery, J.C.11
  • 23
    • 34248548647 scopus 로고    scopus 로고
    • Beta-interferon unbalances the peripheral T cell proinflammatory response in experimental autoimmune encephalomyelitis
    • Martin-Saavedra F.M., Flores N., Dorado B., Eguiluz C., Bravo B., Garcia-Merino A., Ballester S. Beta-interferon unbalances the peripheral T cell proinflammatory response in experimental autoimmune encephalomyelitis. Mol. Immunol. 2007, 44:3597-3607.
    • (2007) Mol. Immunol. , vol.44 , pp. 3597-3607
    • Martin-Saavedra, F.M.1    Flores, N.2    Dorado, B.3    Eguiluz, C.4    Bravo, B.5    Garcia-Merino, A.6    Ballester, S.7
  • 24
    • 49449097216 scopus 로고    scopus 로고
    • Beta interferon restricts the inflammatory potential of CD4(+) cells through the boost of the Th2 phenotype, the inhibition of Th17 response and the prevalence of naturally occurring T regulatory cells
    • Martin-Saavedra F.M., Gonzalez-Garcia C., Bravo B., Ballester S. Beta interferon restricts the inflammatory potential of CD4(+) cells through the boost of the Th2 phenotype, the inhibition of Th17 response and the prevalence of naturally occurring T regulatory cells. Mol. Immunol. 2008, 45:4008-4019.
    • (2008) Mol. Immunol. , vol.45 , pp. 4008-4019
    • Martin-Saavedra, F.M.1    Gonzalez-Garcia, C.2    Bravo, B.3    Ballester, S.4
  • 25
    • 49449097216 scopus 로고    scopus 로고
    • Beta interferon restricts the inflammatory potential of CD4+ cells through the boost of the Th2 phenotype, the inhibition of Th17 response and the prevalence of naturally occurring T regulatory cells
    • Martin-Saavedra F.M., Gonzalez-Garcia C., Bravo B., Ballester S. Beta interferon restricts the inflammatory potential of CD4+ cells through the boost of the Th2 phenotype, the inhibition of Th17 response and the prevalence of naturally occurring T regulatory cells. Mol. Immunol. 2008, 45:4008-4019.
    • (2008) Mol. Immunol. , vol.45 , pp. 4008-4019
    • Martin-Saavedra, F.M.1    Gonzalez-Garcia, C.2    Bravo, B.3    Ballester, S.4
  • 26
    • 0038070602 scopus 로고    scopus 로고
    • Immunolocalization of estrogen receptor beta in the mouse brain: Comparison with estrogen receptor alpha (vol 144, pg 2055, 2003)
    • Mitra S.W. Immunolocalization of estrogen receptor beta in the mouse brain: Comparison with estrogen receptor alpha (vol 144, pg 2055, 2003). Endocrinology 2003, 144:2844-2844.
    • (2003) Endocrinology , vol.144 , pp. 2844-2844
    • Mitra, S.W.1
  • 28
    • 33745773543 scopus 로고    scopus 로고
    • Treatment with an estrogen receptor alpha ligand is neuroprotective in experimental autoimmune encephalomyelitis
    • Morales L.B., Loo K.K., Liu H.B., Peterson C., Tiwari-Woodruff S., Voskuhl R.R. Treatment with an estrogen receptor alpha ligand is neuroprotective in experimental autoimmune encephalomyelitis. J. Neurosci. 2006, 26:6823-6833.
    • (2006) J. Neurosci. , vol.26 , pp. 6823-6833
    • Morales, L.B.1    Loo, K.K.2    Liu, H.B.3    Peterson, C.4    Tiwari-Woodruff, S.5    Voskuhl, R.R.6
  • 29
    • 0034333256 scopus 로고    scopus 로고
    • VLA-4/CD49d downregulated on primed T lymphocytes during interferon-beta therapy in multiple sclerosis
    • Muraro P.A., Leist T., Bielekova B., McFarland H.F. VLA-4/CD49d downregulated on primed T lymphocytes during interferon-beta therapy in multiple sclerosis. J. Neuroimmunol. 2000, 111:186-194.
    • (2000) J. Neuroimmunol. , vol.111 , pp. 186-194
    • Muraro, P.A.1    Leist, T.2    Bielekova, B.3    McFarland, H.F.4
  • 30
    • 10644259532 scopus 로고    scopus 로고
    • Neuroimmunoprotective effects of estrogen and derivatives in experimental autoimmune encephalomyelitis: therapeutic implications for multiple sclerosis
    • Offner H. Neuroimmunoprotective effects of estrogen and derivatives in experimental autoimmune encephalomyelitis: therapeutic implications for multiple sclerosis. J. Neurosci. Res. 2004, 78:603-624.
    • (2004) J. Neurosci. Res. , vol.78 , pp. 603-624
    • Offner, H.1
  • 34
    • 0034951492 scopus 로고    scopus 로고
    • Interferon-beta treatment of experimental autoimmune encephalomyelitis leads to rapid nonapoptotic termination of T cell infiltration
    • Schmidt J., Sturzebecher S., Toyka K.V., Gold R. Interferon-beta treatment of experimental autoimmune encephalomyelitis leads to rapid nonapoptotic termination of T cell infiltration. J. Neurosci. Res. 2001, 65:59-67.
    • (2001) J. Neurosci. Res. , vol.65 , pp. 59-67
    • Schmidt, J.1    Sturzebecher, S.2    Toyka, K.V.3    Gold, R.4
  • 35
    • 44449146212 scopus 로고    scopus 로고
    • Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin
    • Shinohara M.L., Kim J.H., Garcia V.A., Cantor H. Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin. Immunity 2008, 29:68-78.
    • (2008) Immunity , vol.29 , pp. 68-78
    • Shinohara, M.L.1    Kim, J.H.2    Garcia, V.A.3    Cantor, H.4
  • 36
    • 33846966636 scopus 로고    scopus 로고
    • A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage
    • Steinman L. A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage. Nat. Med. 2007, 13:139-145.
    • (2007) Nat. Med. , vol.13 , pp. 139-145
    • Steinman, L.1
  • 37
    • 58749105841 scopus 로고    scopus 로고
    • IL-23 promotes maintenance but not commitment to the Th17 lineage
    • Stritesky G.L., Yeh N., Kaplan M.H. IL-23 promotes maintenance but not commitment to the Th17 lineage. J. Immunol. 2008, 181:5948-5955.
    • (2008) J. Immunol. , vol.181 , pp. 5948-5955
    • Stritesky, G.L.1    Yeh, N.2    Kaplan, M.H.3
  • 38
    • 77249179822 scopus 로고    scopus 로고
    • The role of IL-17 and IFN-gamma in defining pathogenic potential of T cells in EAE
    • Stromnes I., Goverman J., Liggitt D. The role of IL-17 and IFN-gamma in defining pathogenic potential of T cells in EAE. Clin. Immunol. 2007, 123:S61-S62.
    • (2007) Clin. Immunol. , vol.123
    • Stromnes, I.1    Goverman, J.2    Liggitt, D.3
  • 39
    • 35548975206 scopus 로고    scopus 로고
    • Differential neuroprotective and antiinflammatory effects of estrogen receptor (ER)alpha and ERbeta ligand treatment
    • Tiwari-Woodruff S., Morales L.B., Lee R., Voskuhl R.R. Differential neuroprotective and antiinflammatory effects of estrogen receptor (ER)alpha and ERbeta ligand treatment. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:14813-14818.
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 14813-14818
    • Tiwari-Woodruff, S.1    Morales, L.B.2    Lee, R.3    Voskuhl, R.R.4
  • 40
    • 0032796747 scopus 로고    scopus 로고
    • Axonal pathology in multiple sclerosis: relationship to neurologic disability
    • Trapp B.D., Ransohoff R., Rudick R. Axonal pathology in multiple sclerosis: relationship to neurologic disability. Curr. Opin. Neurol. 1999, 12:295-302.
    • (1999) Curr. Opin. Neurol. , vol.12 , pp. 295-302
    • Trapp, B.D.1    Ransohoff, R.2    Rudick, R.3
  • 41
    • 59449090979 scopus 로고    scopus 로고
    • Oestrogen modulates experimental autoimmune encephalomyelitis and interleukin-17 production via programmed death 1
    • Wang C., Dehghani B., Li Y., Kaler L.J., Vandenbark A.A., Offner H. Oestrogen modulates experimental autoimmune encephalomyelitis and interleukin-17 production via programmed death 1. Immunology 2009, 126:329-335.
    • (2009) Immunology , vol.126 , pp. 329-335
    • Wang, C.1    Dehghani, B.2    Li, Y.3    Kaler, L.J.4    Vandenbark, A.A.5    Offner, H.6
  • 42
    • 64849102732 scopus 로고    scopus 로고
    • Membrane estrogen receptor regulates experimental autoimmune encephalomyelitis through up-regulation of programmed death 1
    • Wang C., Dehghani B., Li Y.X., Kaler L.J., Proctor T., Vandenbark A.A., Offner H. Membrane estrogen receptor regulates experimental autoimmune encephalomyelitis through up-regulation of programmed death 1. J. Immunol. 2009, 182:3294-3303.
    • (2009) J. Immunol. , vol.182 , pp. 3294-3303
    • Wang, C.1    Dehghani, B.2    Li, Y.X.3    Kaler, L.J.4    Proctor, T.5    Vandenbark, A.A.6    Offner, H.7
  • 43
    • 24044441632 scopus 로고    scopus 로고
    • 17 beta-Estradiol induced Ca2+ influx via L-type calcium channels activates the Src/ERK/cyclic-amp response element binding protein signal pathway and Bcl-2 expression in rat hippocampal neurons: a potential initiation mechanism for estrogen-induced neuroprotection
    • Wu T.W., Wang J.M., Chen S., Brinton R.D. 17 beta-Estradiol induced Ca2+ influx via L-type calcium channels activates the Src/ERK/cyclic-amp response element binding protein signal pathway and Bcl-2 expression in rat hippocampal neurons: a potential initiation mechanism for estrogen-induced neuroprotection. Neuroscience 2005, 135:59-72.
    • (2005) Neuroscience , vol.135 , pp. 59-72
    • Wu, T.W.1    Wang, J.M.2    Chen, S.3    Brinton, R.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.