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Volumn 57, Issue 6, 2009, Pages 722-728

Erythropoietin can promote survival of cerebral cells by downregulating Bax gene after traumatic brain injury in rats

Author keywords

Bax; Cell death; RhEPO; Traumatic brain injury

Indexed keywords

MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; RECOMBINANT ERYTHROPOIETIN;

EID: 77249089313     PISSN: 00283886     EISSN: 19984022     Source Type: Journal    
DOI: 10.4103/0028-3886.59466     Document Type: Article
Times cited : (21)

References (48)
  • 1
    • 0035869453 scopus 로고    scopus 로고
    • Neuronal expression of a functional receptor for the C5a complement activation fragment
    • O'Barr SA, Caguioa J, Gruol D, Perkins G, Ember JA, Hugli T, et al. Neuronal expression of a functional receptor for the C5a complement activation fragment. J Immunol 2001;166:4154-4162
    • (2001) J Immunol , vol.166 , pp. 4154-4162
    • O'Barr, S.A.1    Caguioa, J.2    Gruol, D.3    Perkins, G.4    Ember, J.A.5    Hugli, T.6
  • 2
    • 29144480517 scopus 로고    scopus 로고
    • Complement-dependent cell death and inflammatory gene changes in murine lupus cerebritis
    • Alexander JJ, Jacob A, Bao L, Macdonald RL, Quigg RJ. Complement-dependent cell death and inflammatory gene changes in murine lupus cerebritis. J Immunol 2005;175:8312-8319
    • (2005) J Immunol , vol.175 , pp. 8312-8319
    • Alexander, J.J.1    Jacob, A.2    Bao, L.3    MacDonald, R.L.4    Quigg, R.J.5
  • 4
  • 5
    • 2442645134 scopus 로고    scopus 로고
    • Moderate and severe traumatic brain injury: Epidemiologic, imaging and neuropathologic perspectives
    • McArthur DL, Chute DJ, Villablanca JP. Moderate and severe traumatic brain injury: Epidemiologic, imaging and neuropathologic perspectives. Brain Pathol 2004;14:185-194
    • (2004) Brain Pathol , vol.14 , pp. 185-194
    • McArthur, D.L.1    Chute, D.J.2    Villablanca, J.P.3
  • 6
    • 13844281636 scopus 로고    scopus 로고
    • Bench-tobedside review: Cell death/programmed cell death triggered by traumatic brain injury
    • Zhang X, Chen Y, Jenkins LW, Kochanek PM, Clark RS. Bench-tobedside review: Cell death/programmed cell death triggered by traumatic brain injury. Crit Care 2005;9:66-75.
    • (2005) Crit Care , vol.9 , pp. 66-75
    • Zhang, X.1    Chen, Y.2    Jenkins, L.W.3    Kochanek, P.M.4    Clark, R.S.5
  • 7
    • 0037133191 scopus 로고    scopus 로고
    • Erythropoietin prevents motor neuron cell death and neurologic disability in experimental spinal cord ischemic injury
    • Celik M, Gökmen N, Erbayraktar S, Akhisaroglu M, Konakc S, Ulukus C, et al. Erythropoietin prevents motor neuron cell death and neurologic disability in experimental spinal cord ischemic injury. Proc Natl Acad Sci U.S.A 2002;99:2258-2263
    • (2002) Proc Natl Acad Sci U.S.A , vol.99 , pp. 2258-2263
    • Celik, M.1    Gökmen, N.2    Erbayraktar, S.3    Akhisaroglu, M.4    Konakc, S.5    Ulukus, C.6
  • 8
    • 0035833541 scopus 로고    scopus 로고
    • Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades
    • Digicaylioglu M, Lipton SA. Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades. Nature (Lond) 2001;412:641-647
    • (2001) Nature (Lond) , vol.412 , pp. 641-647
    • Digicaylioglu, M.1    Lipton, S.A.2
  • 9
    • 0036913056 scopus 로고    scopus 로고
    • Neuroprotection and traumatic brain injury: Theoretical option or realistic proposition
    • Faden AI. Neuroprotection and traumatic brain injury: Theoretical option or realistic proposition. Curr Opin Neurol 2002;15:707-712
    • (2002) Curr Opin Neurol , vol.15 , pp. 707-712
    • Faden, A.I.1
  • 10
    • 0019421846 scopus 로고
    • Responses to cortical injury: I. Methodology and local effects of contusions in the rat
    • Feeney DM, Boyeson MG, Linn RT, Murray HM, Dail WG. Responses to cortical injury: I. Methodology and local effects of contusions in the rat. Brain Res 1981;211:67-77.
    • (1981) Brain Res , vol.211 , pp. 67-77
    • Feeney, D.M.1    Boyeson, M.G.2    Linn, R.T.3    Murray, H.M.4    Dail, W.G.5
  • 11
    • 0035503014 scopus 로고    scopus 로고
    • Physiological and structural evidence for hippocampal involvement in persistent seizure susceptibility after traumatic brain injury
    • Golarai G, Greenwood AC, Feeney DM, Connor JA. Physiological and structural evidence for hippocampal involvement in persistent seizure susceptibility after traumatic brain injury. J Neurosci 2001;21:8523-8537
    • (2001) J Neurosci , vol.21 , pp. 8523-8537
    • Golarai, G.1    Greenwood, A.C.2    Feeney, D.M.3    Connor, J.A.4
  • 12
    • 0037047154 scopus 로고    scopus 로고
    • Recombinant human erythropoietin counteracts secondary injury and markedly enhances neurological recovery from experimental spinal cord trauma
    • Gorio A, Gokmen N, Erbayraktar S, Yilmaz O, Madaschi L, Cichetti C, et al. Recombinant human erythropoietin counteracts secondary injury and markedly enhances neurological recovery from experimental spinal cord trauma. Proc Natl Acad Sci U.S.A 2002;99: 9450-9455
    • (2002) Proc Natl Acad Sci U.S.A , vol.99 , pp. 9450-9455
    • Gorio, A.1    Gokmen, N.2    Erbayraktar, S.3    Yilmaz, O.4    Madaschi, L.5    Cichetti, C.6
  • 13
    • 0042355359 scopus 로고    scopus 로고
    • Critical role for Akt1 in the modulation of apoptotic phosphatidylserine exposure and microglial activation
    • Kang JQ, Chong ZZ, Maiese K. Critical role for Akt1 in the modulation of apoptotic phosphatidylserine exposure and microglial activation. Mol Pharmacol 2003;64:557-569
    • (2003) Mol Pharmacol , vol.64 , pp. 557-569
    • Kang, J.Q.1    Chong, Z.Z.2    Maiese, K.3
  • 15
    • 13544273998 scopus 로고    scopus 로고
    • Caspase-dependent and -independent neuronal death: Two distinct pathways to neuronal injury
    • Stefanis L. Caspase-dependent and -independent neuronal death: Two distinct pathways to neuronal injury. Neuroscientist 2005;11:50-62.
    • (2005) Neuroscientist , vol.11 , pp. 50-62
    • Stefanis, L.1
  • 16
    • 15244341057 scopus 로고    scopus 로고
    • Erythropoietin after focal cerebral ischemia activates the Janus kinase-signal transducer and activator of transcription signaling pathway and improves brain injury in postnatal day 7 rats
    • Sola A, Rogido M, Lee BH, Genetta T, Wen TC. Erythropoietin after focal cerebral ischemia activates the Janus kinase-signal transducer and activator of transcription signaling pathway and improves brain injury in postnatal day 7 rats. Pediatr Res 2005;57:481-487
    • (2005) Pediatr Res , vol.57 , pp. 481-487
    • Sola, A.1    Rogido, M.2    Lee, B.H.3    Genetta, T.4    Wen, T.C.5
  • 17
    • 4944256085 scopus 로고    scopus 로고
    • Caspase inhibitor z-DEVD-fmk attenuates calpain and necrotic cell death in vitro and after traumatic brain injury
    • Knoblach SM, Alroy DA, Nikolaeva M, Cernak I, Stoica BA, Faden AI. Caspase inhibitor z-DEVD-fmk attenuates calpain and necrotic cell death in vitro and after traumatic brain injury. J Cereb Blood Flow Metab 2004;24:1119-1132
    • (2004) J Cereb Blood Flow Metab , vol.24 , pp. 1119-1132
    • Knoblach, S.M.1    Alroy, D.A.2    Nikolaeva, M.3    Cernak, I.4    Stoica, B.A.5    Faden, A.I.6
  • 18
    • 3042690166 scopus 로고    scopus 로고
    • Pathogenesis of hippocampal neuronal death after hypoxia-ischemia changes during brain development
    • Liu CL, Siesjo BK, Hu BR. Pathogenesis of hippocampal neuronal death after hypoxia-ischemia changes during brain development. Neuroscience 2004;127:113-123
    • (2004) Neuroscience , vol.127 , pp. 113-123
    • Liu, C.L.1    Siesjo, B.K.2    Hu, B.R.3
  • 19
    • 31344482594 scopus 로고    scopus 로고
    • Complement activation after lumbosacral ventral root avulsion injury
    • Ohlsson M, Havton LA. Complement activation after lumbosacral ventral root avulsion injury. Neurosci Lett 2005;394:179-183
    • (2005) Neurosci Lett , vol.394 , pp. 179-183
    • Ohlsson, M.1    Havton, L.A.2
  • 20
    • 1042266617 scopus 로고    scopus 로고
    • Mechanisms of erythropoietin- induced brain protection in neonatal hypoxia-ischemia rat model
    • Sun Y, Zhou C, Polk P, Nanda A, Zhang JH. Mechanisms of erythropoietin- induced brain protection in neonatal hypoxia-ischemia rat model. J Cereb Blood Flow Metab 2004;24:259-270
    • (2004) J Cereb Blood Flow Metab , vol.24 , pp. 259-270
    • Sun, Y.1    Zhou, C.2    Polk, P.3    Nanda, A.4    Zhang, J.H.5
  • 21
    • 38349094545 scopus 로고    scopus 로고
    • Recombinant human erythropoietin administration protects cortical neurons from traumatic brain injury in rats
    • Liao ZB, Zhi XG, Shi QH, He ZH. Recombinant human erythropoietin administration protects cortical neurons from traumatic brain injury in rats. Eur J Neurol 2008;15:140-149
    • (2008) Eur J Neurol , vol.15 , pp. 140-149
    • Liao, Z.B.1    Zhi, X.G.2    Shi, Q.H.3    He, Z.H.4
  • 22
    • 4444351598 scopus 로고    scopus 로고
    • Necrosis, cell death and hybrid death in the cortex and thalamus after barrel cortex ischemia in rats
    • Wei L, Ying DJ, Cui L, Langsdorf J, Yu SP. Necrosis, cell death and hybrid death in the cortex and thalamus after barrel cortex ischemia in rats. Brain Res 2004;1022:54-61.
    • (2004) Brain Res , vol.1022 , pp. 54-61
    • Wei, L.1    Ying, D.J.2    Cui, L.3    Langsdorf, J.4    Yu, S.P.5
  • 23
    • 26444572335 scopus 로고    scopus 로고
    • Erythropoietin is neuroprotective, improves functional recovery, and reduces neuronal cell death and inflammation in a rodent model of experimental closed head injury
    • Yatsiv I, Grigoriadis N, Simeonidou C, Stahel PF, Schmidt OI, Alexandrovitch AG, et al. Erythropoietin is neuroprotective, improves functional recovery, and reduces neuronal cell death and inflammation in a rodent model of experimental closed head injury. Faseb J 2005;12:1701-1703
    • (2005) Faseb J , vol.12 , pp. 1701-1703
    • Yatsiv, I.1    Grigoriadis, N.2    Simeonidou, C.3    Stahel, P.F.4    Schmidt, O.I.5    Alexandrovitch, A.G.6
  • 25
    • 0038374983 scopus 로고    scopus 로고
    • Time course of cellular pathology after controlled cortical impact injury
    • Chen S, Pickard JD, Harris NG. Time course of cellular pathology after controlled cortical impact injury. Exp Neurol 2003;182:87-102.
    • (2003) Exp Neurol , vol.182 , pp. 87-102
    • Chen, S.1    Pickard, J.D.2    Harris, N.G.3
  • 26
    • 0037365196 scopus 로고    scopus 로고
    • Erythropoietin fosters both intrinsic and extrinsic neuronal protection through modulation of microglia, Akt1, Bad, and caspase-mediated pathways
    • Chong ZZ, Kang JQ, Maiese K. Erythropoietin fosters both intrinsic and extrinsic neuronal protection through modulation of microglia, Akt1, Bad, and caspase-mediated pathways. Br J Pharmacol 2003;138:1107-1118
    • (2003) Br J Pharmacol , vol.138 , pp. 1107-1118
    • Chong, Z.Z.1    Kang, J.Q.2    Maiese, K.3
  • 27
    • 0038297283 scopus 로고    scopus 로고
    • Intracerebroventricular injection of terminal complement complex causes inflammatory reaction in the rat brain
    • Casarsa C, de Luigi A, Pausa M, de Simoni MG, Tedesco F. Intracerebroventricular injection of terminal complement complex causes inflammatory reaction in the rat brain. Eur J Immunol 2003;33:1260-1270
    • (2003) Eur J Immunol , vol.33 , pp. 1260-1270
    • Casarsa, C.1    De Luigi, A.2    Pausa, M.3    De Simoni, M.G.4    Tedesco, F.5
  • 28
    • 0037322558 scopus 로고    scopus 로고
    • Formation of complement membrane attack complex in mammalian cerebral cortex evokes seizures and neurodegeneration
    • Xiong ZQ, Qian W, Suzuki K, McNamara JO. Formation of complement membrane attack complex in mammalian cerebral cortex evokes seizures and neurodegeneration. J Neurosci 2003;23:955-960
    • (2003) J Neurosci , vol.23 , pp. 955-960
    • Xiong, Z.Q.1    Qian, W.2    Suzuki, K.3    McNamara, J.O.4
  • 29
    • 0035479019 scopus 로고    scopus 로고
    • Enhanced glial activation and expression of specific CNS inflammation-related molecules in aged versus young rats following cortical stab injury
    • Kyrkanides S, O'Banion MK, Whiteley PE, Daeschner JC, Olschowka JA. Enhanced glial activation and expression of specific CNS inflammation-related molecules in aged versus young rats following cortical stab injury. J Neuroimmunol 2001;119:268-277
    • (2001) J Neuroimmunol , vol.119 , pp. 268-277
    • Kyrkanides, S.1    O'Banion, M.K.2    Whiteley, P.E.3    Daeschner, J.C.4    Olschowka, J.A.5
  • 30
    • 0041835960 scopus 로고    scopus 로고
    • Central nervous system-targeted complement inhibition mediates neuroprotection after closed head injury in transgenic mice
    • Rancan M, Morganti-Kossmann MC, Barnum SR, Saft S, Schmidt OI, Ertel W, et al. Central nervous system-targeted complement inhibition mediates neuroprotection after closed head injury in transgenic mice. J Cereb Blood Flow Metab 2003;23:1070-1074
    • (2003) J Cereb Blood Flow Metab , vol.23 , pp. 1070-1074
    • Rancan, M.1    Morganti-Kossmann, M.C.2    Barnum, S.R.3    Saft, S.4    Schmidt, O.I.5    Ertel, W.6
  • 31
    • 33645079378 scopus 로고    scopus 로고
    • Complement regulator loss on apoptotic neuronal cells causes increased complement activation and promotes both phagocytosis and cell lysis
    • Cole DS, Hughes TR, Gasque P, Morgan BP. Complement regulator loss on apoptotic neuronal cells causes increased complement activation and promotes both phagocytosis and cell lysis. Mol Immunol 2006;43:1953-1964
    • (2006) Mol Immunol , vol.43 , pp. 1953-1964
    • Cole, D.S.1    Hughes, T.R.2    Gasque, P.3    Morgan, B.P.4
  • 32
    • 0347990376 scopus 로고    scopus 로고
    • The neurophysiology of brain injury
    • Gaetz M. The neurophysiology of brain injury. Clin Neurophysiol 2004;115:4-18.
    • (2004) Clin Neurophysiol , vol.115 , pp. 4-18
    • Gaetz, M.1
  • 33
    • 0033782260 scopus 로고    scopus 로고
    • Caspase pathways, neuronal cell death, and CNS injury
    • Eldadah BA, Faden AI. Caspase pathways, neuronal cell death, and CNS injury. J Neurotrauma 2000;17:811-829
    • (2000) J Neurotrauma , vol.17 , pp. 811-829
    • Eldadah, B.A.1    Faden, A.I.2
  • 34
    • 2442687858 scopus 로고    scopus 로고
    • Cell death mechanisms following traumatic brain injury
    • Raghupathi R. Cell death mechanisms following traumatic brain injury. Brain Pathol 2004;14:215-222
    • (2004) Brain Pathol , vol.14 , pp. 215-222
    • Raghupathi, R.1
  • 36
    • 0034703412 scopus 로고    scopus 로고
    • Intracerebral complement C5a receptor (CD88) expression is regulated by TNF and lymphotoxin-alpha following closed head injury in mice
    • Stahel PF, Kariya K, Shohami E, Barnum SR, Eugster H, Trentz O, et al. Intracerebral complement C5a receptor (CD88) expression is regulated by TNF and lymphotoxin-alpha following closed head injury in mice. J Neuroimmunol 2000;109:164-172
    • (2000) J Neuroimmunol , vol.109 , pp. 164-172
    • Stahel, P.F.1    Kariya, K.2    Shohami, E.3    Barnum, S.R.4    Eugster, H.5    Trentz, O.6
  • 37
    • 29744452839 scopus 로고    scopus 로고
    • Administration of vaccinia virus complement control protein shows significant cognitive improvement in a mild injury model
    • Pillay NS, Kellaway LA, Kotwal GJ. Administration of vaccinia virus complement control protein shows significant cognitive improvement in a mild injury model. Ann N Y Acad Sci 2005;1056:450-461
    • (2005) Ann N y Acad Sci , vol.1056 , pp. 450-461
    • Pillay, N.S.1    Kellaway, L.A.2    Kotwal, G.J.3
  • 38
    • 33746930853 scopus 로고    scopus 로고
    • Pharmacological complement inhibition at the C3 convertase level promotes neuronal survival, neuroprotective intracerebral gene expression, and neurological outcome after traumatic brain injury
    • Leinhase I, Schmidt OI, Thurman JM, Hossini AM, Rozanski M, Taha Me, et al. Pharmacological complement inhibition at the C3 convertase level promotes neuronal survival, neuroprotective intracerebral gene expression, and neurological outcome after traumatic brain injury. Exp Neurol 2006;199:454-464
    • (2006) Exp Neurol , vol.199 , pp. 454-464
    • Leinhase, I.1    Schmidt, O.I.2    Thurman, J.M.3    Hossini, A.M.4    Rozanski, M.5    Me, T.6
  • 39
    • 33748484079 scopus 로고    scopus 로고
    • The role of the complement system in CNS inflammatory diseases
    • Stahel PF, Barnum SR. The role of the complement system in CNS inflammatory diseases. Expert Rev Clin Immunol 2006;2:445-456
    • (2006) Expert Rev Clin Immunol , vol.2 , pp. 445-456
    • Stahel, P.F.1    Barnum, S.R.2
  • 40
    • 2442667974 scopus 로고    scopus 로고
    • The alternative pathway of complement in disease: Opportunities for therapeutic targeting
    • Holers VM, Thurman JM. The alternative pathway of complement in disease: Opportunities for therapeutic targeting. Mol Immunol 2004;41:147-152
    • (2004) Mol Immunol , vol.41 , pp. 147-152
    • Holers, V.M.1    Thurman, J.M.2
  • 41
    • 0037310683 scopus 로고    scopus 로고
    • Lack of a functional alternative complement pathway ameliorates ischemic acute renal failure in mice
    • Thurman JM, Ljubanovic D, Edelstein CL, Gilkeson GS, Holers VM. Lack of a functional alternative complement pathway ameliorates ischemic acute renal failure in mice. J Immunol 2003;170:1517-1523
    • (2003) J Immunol , vol.170 , pp. 1517-1523
    • Thurman, J.M.1    Ljubanovic, D.2    Edelstein, C.L.3    Gilkeson, G.S.4    Holers, V.M.5
  • 42
    • 12344333421 scopus 로고    scopus 로고
    • Acute tubular necrosis is characterized by activation of the alternative pathway of complement
    • Thurman JM, Lucia MS, Ljubanovic D, Holers VM. Acute tubular necrosis is characterized by activation of the alternative pathway of complement. Kidney Int 2005;67:524-530
    • (2005) Kidney Int , vol.67 , pp. 524-530
    • Thurman, J.M.1    Lucia, M.S.2    Ljubanovic, D.3    Holers, V.M.4
  • 43
    • 31144460785 scopus 로고    scopus 로고
    • The central role of the alternative complement pathway in human disease
    • Thurman JM, Holers VM. The central role of the alternative complement pathway in human disease. J Immunol 2006;176:1305-1310
    • (2006) J Immunol , vol.176 , pp. 1305-1310
    • Thurman, J.M.1    Holers, V.M.2
  • 45
    • 12144288766 scopus 로고    scopus 로고
    • Neuron-specific mRNA complexity responses during hippocampal cell death after traumatic brain injury
    • Marciano PG, Brettschneider J, Manduchi E, Davis JE, Eastman S, Raghupathi R, et al. Neuron-specific mRNA complexity responses during hippocampal cell death after traumatic brain injury. J Neurosci 2004;24:2866-2876
    • (2004) J Neurosci , vol.24 , pp. 2866-2876
    • Marciano, P.G.1    Brettschneider, J.2    Manduchi, E.3    Davis, J.E.4    Eastman, S.5    Raghupathi, R.6
  • 46
    • 27744503953 scopus 로고    scopus 로고
    • CD46 plays a key role in tailoring innate immune recognition of apoptotic and necrotic cells
    • Elward K, Griffiths M, Mizuno M, Harris CL, Neal JW, Morgan BP, et al. CD46 plays a key role in tailoring innate immune recognition of apoptotic and necrotic cells. J Biol Chem 2005;280:36342-36354
    • (2005) J Biol Chem , vol.280 , pp. 36342-36354
    • Elward, K.1    Griffiths, M.2    Mizuno, M.3    Harris, C.L.4    Neal, J.W.5    Morgan, B.P.6
  • 47
    • 0034669915 scopus 로고    scopus 로고
    • Attenuation of experimental autoimmune demyelination in complement- deficient mice
    • Nataf S, Carroll SL, Wetsel RA, Szalai AJ, Barnum SR. Attenuation of experimental autoimmune demyelination in complement- deficient mice. J Immunol 2000;165:5867-5873
    • (2000) J Immunol , vol.165 , pp. 5867-5873
    • Nataf, S.1    Carroll, S.L.2    Wetsel, R.A.3    Szalai, A.J.4    Barnum, S.R.5


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