Effects of estradiol on cerebrospinal fluid levels of agouti-related protein in ovariectomized rhesus monkeys

Endocrinology

Volumn 151, Issue 3, 2010, Pages 1002-1009

  Xiao, Ennian ^a   Kim, Andrea J ^a   Dutia, Roxanne ^a   Conwell, Irene ^a   Ferin, Michel ^a   Wardlaw, Sharon L ^a  

^a Columbia University College of Physicians and Surgeons ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGOUTI RELATED PROTEIN; ESTRADIOL; HORMONE PRECURSOR; MELANOCORTIN; PROOPIOMELANOCORTIN;

ANIMAL EXPERIMENT; ARTICLE; BODY MASS; CEREBROSPINAL FLUID; CEREBROSPINAL FLUID LEVEL; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HYPOTHALAMUS; IMMUNOREACTIVITY; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; RHESUS MONKEY; SENSITIVITY ANALYSIS;

AGOUTI-RELATED PROTEIN; ANIMALS; ESTRADIOL; FEMALE; HYPOTHALAMUS; MACACA MULATTA; OVARIECTOMY; PRO-OPIOMELANOCORTIN;

EID: 77149176244     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2009-0853     Document Type: Article

References (49)

1. Turgeon JL, Carr MC, Maki PM, Mendelsohn ME, Wise PM 2006 Complex actions of sex steroids in adipose tissue, the cardiovascular system, and brain: insights from basic science and clinical studies. Endocr Rev 27:575-605
2. Salpeter SR, Walsh JM, Ormiston TM, Greyber E, Buckley NS, Salpeter EE 2006 Meta-analysis: effect of hormone-replacement therapy on components of the metabolic syndrome in postmenopausal women. Diabetes Obes Metab 8:538-554 3. Rogers NH, Perfield 2nd JW, Strissel KJ, Obin MS, Greenberg AS 2009 Reduced energy expenditure and increased inflammation are early events in the development of ovariectomy-induced obesity. Endocrinology 150:2161-2168
3. Asarian L, Geary N 2002 Cyclic estradiol treatment normalizes body weight and restores physiological patterns of spontaneous feeding and sexual receptivity in ovariectomized rats. Horm Behav 42:461-471
4. Heine PA, Taylor JA, Iwamoto GA, Lubahn DB, Cooke PS 2000 Increased adipose tissue in male and female estrogen receptor-α knockout mice. Proc Nat Acad Sci USA 97:12729-12734
5. Jones ME, Thorburn AW, Britt KL, Hewitt KN, Wreford NG, Proietto J, Oz OK, Leury BJ, Robertson KM, Yao S, Simpson ER 2000 Aromatase-deficient (ArKO) mice have a phenotype of increased adiposity. Proc Nat Acad Sci USA 97:12735-12740
6. Espeland MA, Stefanick ML, Kritz-Silverstein D, Fineberg SE, Waclawiw MA, James MK, Greendale GA; Postmenopausal Estrogen-Progestin Interventions Study Investigators 1997 Effect of postmenopausal hormone therapy on body weight and waist and hip girths. J Clin Endocrinol Metab 82:1549-1556
7. Mattiasson I, Rendell M, Törnquist C, Jeppsson S, Hulthén UL 2002 Effects of estrogen replacement therapy on abdominal fat compartments as related to glucose and lipid metabolism in early postmenopausal women. Horm Metab Res 34:583-588
8. Carr MC 2003 The emergence of the metabolic syndrome with menopause. J Clin Endocrinol Metab 88:2404-2411
9. Lovejoy JC, Champagne CM, de Jonge L, Xie H, Smith SR 2008 Increased visceral fat and decreased energy expenditure during the menopausal transition. Int J Obes 32:949-958
10. Simerly RB, Chang C, Muramatsu M, Swanson LW 1990 Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: an in situ hybridization study. J Comp Neurol 294:76-95
11. Lee M, Wardlaw SL 2007 The central melanocortin system and the regulation of energy balance. Front Biosci 12:3994-4010
12. Cowley MA, Pronchuk N, Fan W, Dinulescu DM, Colmers WF, Cone RD 1999 Integration of NPY, AGRP, and melanocortin signals in the hypothalamic paraventricular nucleus: evidence of a cellular basis for the adipostat. Neuron 24:155-163
13. Broberger C, Johansen J, Johansson C, Schalling M, Hökfelt T 1998 The neuropeptide Y/agouti gene-related protein (AGRP) brain circuitry in normal, anorectic, and monosodium glutamate-treated mice. Proc Nat Acad Sci USA 95:15043-15048
14. Morrell JI, McGinty JF, Pfaff DW 1985 A subset of β-endorphin- or dynorphin-containing neurons in the medial basal hypothalamus accumulates estradiol. Neuroendocrinology 41:417-426
15. Titolo D, Cai F, Belsham DD 2006 Coordinate regulation of neuropeptide Y and agouti-related peptide gene expression by estrogen depends on the ratio of estrogen receptor (ER) α to ERβ in clonal hypothalamic neurons. Mol Endocrinol 20:2080-2092
16. Acosta-Martinez M, Horton T, Levine JE 2007 Estrogen receptors in neuropeptide Y neurons: at the crossroads of feeding and reproduction. Trends Endocrinol Metab 18:48-50
17. Gao Q, Horvath TL 2008 Crosstalk between estrogen and leptin signaling in the hypothalamus. Am J Physiol Endocrinol Metab 294: E817-E826
18. Wardlaw SL, Wehrenberg WB, Ferin M, Carmel PW, Frantz AG 1980 High levels of β-endorphin in hypophyseal portal blood. Endocrinology 106:1323-1326
19. Wardlaw SL, Wehrenberg WB, Ferin M, Antunes JL, Frantz AG 1982 Effect of sex steroids on β-endorphin in hypophyseal portal blood. J Clin Endocrinol Metab 55:877-881
20. Wehrenberg WB, Wardlaw SL, Frantz AG, Ferin M 1982 β-Endorphin in hypophyseal portal blood: variations throughout the menstrual cycle. Endocrinology 111:879-881
21. Tsigos C, Crosby SR, Gibson S, Young RJ, White A 1993 Proopiomelanocortin is the predominant adrenocorticotropin-related peptide in human cerebrospinal fluid. J Clin Endocrinol Metab 76:620-624
22. Pritchard LE, Oliver RL, McLoughlin JD, Birtles S, Lawrence CB, Turnbull AV, White A 2003 Proopiomelanocortin-derived peptides in rat cerebrospinal fluid and hypothalamic extracts: evidence that secretion is regulated with respect to energy balance. Endocrinology 144:760-766
23. Creemers JW, Pritchard LE, Gyte A, Le Rouzic P, Meulemans S, Wardlaw SL, Zhu X, Steiner DF, Davies N, Armstrong D, Lawrence CB, Luckman SM, Schmitz CA, Davies RA, Brennand JC, White A 2006 Agouti-related protein is posttranslationally cleaved by proprotein convertase 1 to generate agouti-related protein (AGRP)83-132: interaction between AGRP83-132 and melanocortin receptors cannot be influenced by syndecan-3. Endocrinology 147:1621-1631
24. Jackson PJ, Douglas NR, Chai B, Binkley J, Sidow A, Barsh GS, Millhauser GL 2006 Structural and molecular evolutionary analysis of agouti and agouti-related proteins. Chem Biol 13:1297-1305
25. Jen KL, Hansen BC, Metzger BL 1985 Adiposity, anthropometric measures, and plasma insulin levels of rhesus monkeys. Int J Obes 9:213-224
26. Papadopoulos AD, Wardlaw SL 1999 Endogenous α-MSH modulates the hypothalamic-pituitary-adrenal response to the cytokine interleukin-1β. J Neuroendocrinol 11:315-319
27. Breen TL, Conwell IM, Wardlaw SL 2005 Effects of fasting, leptin, and insulin on AGRP and POMC peptide release in the hypothalamus. Brain Res 1032:141-148
28. Schlachter LB, Wardlaw SL, Tindall GT, Frantz AG 1983 Persistence of β-endorphin in human cerebrospinal fluid after hypophysectomy. J Clin Endocrinol Metab 57:221-224
29. Haskell-Luevano C, Chen P, Li C, Chang K, Smith MS, Cameron JL, Cone RD 1999 Characterization of the neuroanatomical distribution of agouti-related protein immunoreactivity in the rhesus monkey and the rat. Endocrinology 140:1408-1415
30. Clegg DJ, Brown LM, Zigman JM, Kemp CJ, Strader AD, Benoit SC, Woods SC, Mangiaracina M, Geary N 2007 Estradiol-dependent decrease in the orexigenic potency of ghrelin in female rats. Diabetes 56:1051-1058
31. Wardlaw SL, Thoron L, Frantz AG 1982 Effects of sex steroids on brain β-endorphin. Brain Res 245:327-331
32. Wilcox JN, Roberts JL 1985 Estrogen decreases rat hypothalamic proopiomelanocortin messenger ribonucleic acid levels. Endocrinology 117:2392-2396
33. Wise PM, Scarbrough K, Weiland NG, Larson GH 1990 Diurnal pattern of proopiomelanocortin gene expression in the arcuate nucleus of proestrous, ovariectomized, and steroid-treated rats: a possible role in cyclic luteinizing hormone secretion. Mol Endocrinol 4:886-892
34. Treiser SL, Wardlaw SL 1992 Estradiol regulation of proopiomelanocortin gene expression and peptide content in the hypothalamus. Neuroendocrinology 55:167-173
35. Bohler Jr HC, Tracer H, Merriam GR, Petersen SL 1991 Changes in proopiomelanocortin messenger ribonucleic acid levels in the rostral periarcuate region of the female rat during the estrous cycle. Endocrinology 128:1265-1269
36. Pelletier G, Li S, Luu-The V, Labrie F 2007 Oestrogenic regulation of pro-opiomelanocortin, neuropeptide Y and corticotrophin-releasing hormone mRNAs in mouse hypothalamus. J Neuroendocrinol 19:426-431
37. Sarkar DK, Yen SS 1985 Changes in β-endorphin-like immunoreactivity in pituitary portal blood during the estrous cycle and after ovariectomy in rats. Endocrinology 116:2075-2079
38. Sanchez VC, Goldstein J, Stuart RC, Hovanesian V, Huo L, Munzberg H, Friedman TC, Bjorbaek C, Nillni EA 2004 Regulation of hypothalamic prohormone convertases 1 and 2 and effects on processing of prothyrotropin- releasing hormone. J Clin Invest 114:357-369
39. Enriori PJ, Evans AE, Sinnayah P, Jobst EE, Tonelli-Lemos L, Billes SK, Glavas MM, Grayson BE, Perello M, Nillni EA, Grove KL, Cowley MA 2007 Diet-induced obesity causes severe but reversible leptin resistance in arcuate melanocortin neurons. Cell Metab 5:181-194
40. Gao Q, Mezei G, Nie Y, Rao Y, Choi CS, Bechmann I, Leranth C, Toran-Allerand D, Priest CA, Roberts JL, Gao XB, Mobbs C, Shulman GI, Diano S, Horvath TL 2007 Anorectic estrogen mimics leptin's effect on the rewiring of melanocortin cells and Stat3 signaling in obese animals. Nat Med 13:89 -94
41. Malyala A, Zhang C, Bryant DN, Kelly MJ, Rønnekleiv OK 2008 PI3K signaling effects in hypothalamic neurons mediated by estrogen. J Comp Neurol 506:895-911
42. El-Haschimi K, Pierroz DD, Hileman SM, Bjørbaek C, Flier JS 2000 Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity. J Clin Invest 105:1827-1832
43. + channel signaling in the arcuate nucleus. Endocrinology 148:4937-4951
44. Gao Q, Horvath TL 2007 Neurobiology of feeding and energy expenditure. Annu Rev Neurosci 30:367-398
45. Bennett PA, Lindell K, Karlsson C, Robinson IC, Carlsson LM, Carlsson B 1998 Differential expression and regulation of leptin receptor isoforms in the rat brain: effects of fasting and oestrogen. Neuroendocrinology 67:29-36
46. Lindell K, Bennett PA, Itoh Y, Robinson IC, Carlsson LM, Carlsson B 2001 Leptin receptor 5′untranslated regions in the rat: relative abundance, genomic organization and relation to putative response elements. Mol Cell Endocrinol 172:37-45
47. Clegg DJ, Brown LM, Woods SC, Benoit SC 2006 Gonadal hormones determine sensitivity to central leptin and insulin. Diabetes 55:978-987
48. Pritchard LE, White A 2007 Neuropeptide processing and its impact on melanocortin pathways. Endocrinology 148:4201-4207
49. Musatov S, Chen W, Pfaff DW, Mobbs CV, Yang XJ, Clegg DJ, Kaplitt MG, Ogawa S 2007 Silencing of estrogen receptor α in the ventromedial nucleus of hypothalamus leads to metabolic syndrome. Proc Natl Acad Sci USA 104:2501-2506