Homodimerization of IL-2 receptor β chain is necessary and sufficient to activate Jak2 and dowstream signaling pathways

FEBS Letters

Volumn 421, Issue 1, 1998, Pages 32-36

  Ferrag, Fatima ^a   Pezet, Alain ^a   Chiarenza, Andrea ^a   Buteau, Hélène ^a   Nelson, Brad H ^b   Goffin, Vincent ^a   Kelly, P A ^a  

^a INSERM   (France)

^b Fred Hutchinson Cancer Research Center   (United States)

Author keywords

Cytokine receptor; Dimerization; Janus kinase; Signal transduction; Specificity

Indexed keywords

BETA CASEIN; CELL RECEPTOR; CYTOKINE RECEPTOR; ERYTHROPOIETIN; ERYTHROPOIETIN RECEPTOR; INTERLEUKIN 2 RECEPTOR; PHOSPHOTYROSINE; PROLACTIN; PROLACTIN RECEPTOR; PROTEIN KINASE; RECEPTOR SUBUNIT; STEM CELL FACTOR;

ANIMAL CELL; ARTICLE; BETA CHAIN; CHO CELL; CONTROLLED STUDY; DIMERIZATION; ENZYME ACTIVATION; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; SIGNAL TRANSDUCTION;

ANIMALS; CASEINS; CHO CELLS; CRICETINAE; DIMERIZATION; DNA-BINDING PROTEINS; ENZYME ACTIVATION; ERYTHROPOIETIN; HUMANS; JANUS KINASE 2; MICE; MILK PROTEINS; PHOSPHORYLATION; PROLACTIN; PROMOTER REGIONS (GENETICS); PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; RECEPTORS, ERYTHROPOIETIN; RECEPTORS, INTERLEUKIN-2; RECEPTORS, PROLACTIN; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; STAT5 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TRANSFECTION;

ANIMALIA; JANUS;

EID: 0032472207     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(97)01529-9     Document Type: Article

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