Secreted form of EphA7 in lung cancer

International Journal of Oncology

Volumn 36, Issue 3, 2010, Pages 635-640

  Tsuboi, Masaru ^a   Mori, Hiroki ^a   Bunai, Tomoyasu ^a   Kageyama, Shinji ^a   Suzuki, Masaya ^a   Okudela, Koji ^a   Takamochi, Kazuya ^a   Ogawa, Hiroshi ^b   Niwa, Hiroshi ^b   Shinmura, Kazuya ^a   Sugimura, Haruhiko ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b SEIREI MIKATAHARA GENERAL HOSPITAL   (Japan)

Author keywords

EPHA7; Lung cancer

Indexed keywords

EPHRIN RECEPTOR A7; MESSENGER RNA;

ADULT; AGED; ARTICLE; CANCER CELL CULTURE; CANCER TISSUE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; HUMAN CELL; LARGE CELL CARCINOMA; LUNG ADENOCARCINOMA; LUNG ALVEOLUS EPITHELIUM; LUNG CANCER; LUNG CARCINOGENESIS; LUNG CARCINOMA; LUNG SMALL CELL CANCER; LUNG SQUAMOUS CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SMOKING; BIOSYNTHESIS; DNA METHYLATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; LUNG TUMOR; METABOLISM; MIDDLE AGED; PROMOTER REGION; TUMOR CELL LINE; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; CELL LINE, TUMOR; DNA METHYLATION; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; PROMOTER REGIONS, GENETIC; RECEPTOR, EPHA7; SMOKING;

EID: 77149162009     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo_00000539     Document Type: Article

References (28)

1. Eph nomenclature and committee: unified nomenclature for Eph family receptors and their ligands, the ephrins. Eph Nomenclature Committee. Cell 90: 403-404, 1997.
2. Pasquale EB: Eph-ephrin bidirectional signaling in physiology and disease. Cell 133: 38-52, 2008.
3. Nakamoto M and Bergemann AD: Diverse roles for the Eph family of receptor tyrosine kinases in carcinogenesis. Microsc Res Tech 59: 58-67, 2002.
4. Noren NK, Lu M, Freeman AL, Koolpe M and Pasquale EB: Interplay between EphB4 on tumor cells and vascular ephrin-B2 regulates tumor growth. Proc Natl Acad Sci USA 101: 5583-5588, 2004.
5. Campbell TN, Attwell S, Arcellana-Panlilio M and Robbins SM: Ephrin A5 expression promotes invasion and transformation of murine fibroblasts. Biochem Biophys Res Commun 350: 623-628, 2006.
6. Tanaka M, Sasaki K, Kamata R and Sakai R: The C-terminus of ephrin-B1 regulates metalloproteinase secretion and invasion of cancer cells. J Cell Sci 120: 2179-2189, 2007.
7. Nakamura R, Kataoka H, Sato N, et al: EPHA2/EFNA1 expression in human gastric cancer. Cancer Sci 96: 42-47, 2005.
8. Wang J, Kataoka H, Suzuki M, et al: Downregulation of EphA7 by hypermethylation in colorectal cancer. Oncogene 24: 5637-5647, 2005.
9. Taddei ML, Parri M, Angelucci A, et al: Kinase-dependent and -independent roles of EphA2 in the regulation of prostate cancer invasion and metastasis. Am J Pathol 174: 1492-1503, 2009.
10. Kataoka H, Igarashi H, Kanamori M, et al: Correlation of EPHA2 overexpression with high microvessel count in human primary colorectal cancer. Cancer Sci 95: 136-141, 2004.
11. Kataoka H, Tanaka M, Kanamori M, et al: Expression profile of EFNB1, EFNB2, two ligands of EPHB2 in human gastric cancer. J Cancer Res Clin Oncol 128: 343-348, 2002.
12. Ding L, Getz G, Wheeler DA, et al: Somatic mutations affect key pathways in lung adenocarcinoma. Nature 455: 1069-1075, 2008.
13. Guan M, Xu C, Zhang F and Ye C: Aberrant methylation of EphA7 in human prostate cancer and its relation to clinico-pathologic features. Int J Cancer 124: 88-94, 2009.
14. Wang J, Li G, Ma H, et al: Differential expression of EphA7 receptor tyrosine kinase in gastric carcinoma. Hum Pathol 38: 1649-1656, 2007.
15. Foster RE, Abdulrahman M, Morris MR, et al: Characterization of a 3;6 translocation associated with renal cell carcinoma. Genes Chromosomes Cancer 46: 311-317, 2007.
16. Tognon C, Knezevich SR, Huntsman D, et al: Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma. Cancer Cell 2: 367-376, 2002.
17. Tomlins SA, Laxman B, Dhanasekaran SM, et al: Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer. Nature 448: 595-599, 2007.
18. Soda M, Choi YL, Enomoto M, et al: Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature 448: 561-566, 2007.
19. Takeuchi K, Choi YL, Togashi Y, et al: KIF5B-ALK, a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer. Clin Cancer Res 15: 3143-3149, 2009.
20. Rikova K, Guo A, Zeng Q, et al: Global survey of phospho-tyrosine signaling identifies oncogenic kinases in lung cancer. Cell 131: 1190-1203, 2007.
21. Okudela K, Suzuki M, Kageyama S, et al: PIK3CA mutation and amplification in human lung cancer. Pathol Int 57: 664-671, 2007.
22. Kleihues Pand L and Sobin H: (eds.) Tumours of the lung, pleura, thymus and heart. IARC Press, Lyon, 2004.
23. Dawson DW, Hong JS, Shen RR, et al: Global DNA methylation profiling reveals silencing of a secreted form of Epha7 in mouse and human germinal center B-cell lymphomas. Oncogene 26: 4243-4252, 2007.
24. Kreyberg L: Relationship of different histological lung tumour groups to tobacco smoking. Br J Cancer 15: 51-53, 1961.
25. Brannan JM, Dong W, Prudkin L, et al: Expression of the receptor tyrosine kinase EphA2 is increased in smokers and predicts poor survival in non-small cell lung cancer. Clin Cancer Res 15: 4423-4430, 2009.
26. Wang LF, Fokas E, Juricko J, et al: Increased expression of EphA7 correlates with adverse outcome in primary and recurrent glioblastoma multiforme patients. BMC Cancer 8: 79, 2008.
27. Noren NK and Pasquale EB: Paradoxes of the EphB4 receptor in cancer. Cancer Res 67: 3994-3997, 2007.
28. Korner M and Miller LJ: Alternative splicing of pre-mRNA in cancer: focus on G protein-coupled peptide hormone receptors. Am J Pathol 175: 461-472, 2009.