HIF-dependent induction of adenosine receptor A2b skews human dendritic cells to a Th2-stimulating phenotype under hypoxia

Immunology and Cell Biology

Volumn 88, Issue 2, 2010, Pages 165-171

  Yang, Meixiang ^a,b   Ma, Chunhong ^b   Liu, Shuxun ^c   Shao, Qianqian ^a   Gao, Wenjuan ^a   Song, Bingfeng ^a   Sun, Jintang ^a   Xie, Qi ^a   Zhang, Yun ^a   Feng, Alei ^a   Liu, Yanguo ^a   Hu, Weixu ^a   Qu, Xun ^a  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Adenosine receptor; Dendritic cells; Hypoxia; Hypoxia inducible factor; Th2

Indexed keywords

ADENOSINE A2B RECEPTOR; ADENOSINE RECEPTOR; CYCLIC AMP; CYTOKINE; GAMMA INTERFERON; HYPOXIA INDUCIBLE FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 12P70; N (4 CYANOPHENYL) 2 [4 (2,3,6,7 TETRAHYDRO 2,6 DIOXO 1,3 DIPROPYL 1H PURIN 8 YL)PHENOXY]ACETAMIDE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL CULTURE; CELL HYPOXIA; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; HUMAN; HUMAN CELL; INTRACELLULAR MEMBRANE; MONOCYTE; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; RECEPTOR UPREGULATION; T LYMPHOCYTE; TH2 CELL;

CELL DIFFERENTIATION; CELL HYPOXIA; CELL POLARITY; CYCLIC AMP; CYTOKINES; DENDRITIC CELLS; GENE KNOCKDOWN TECHNIQUES; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTERLEUKIN-12; INTRACELLULAR SPACE; LIPOPOLYSACCHARIDES; LYMPHOCYTE ACTIVATION; PHENOTYPE; RECEPTOR, ADENOSINE A1; RECEPTOR, ADENOSINE A2A; RECEPTOR, ADENOSINE A2B; RECEPTOR, ADENOSINE A3; TH2 CELLS;

EID: 77149154994     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2009.77     Document Type: Article

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