Interleukin-6 (G-174C) and tumour necrosis factor-alpha (G-308A) gene polymorphisms in geriatric patients with chronic periodontitis

Gerodontology

Volumn 27, Issue 1, 2010, Pages 70-75

  Costa, A M ^a   Guimaraes M C M ^a   De Souza, Elias Rosa ^a   Nobrega O T ^a,b   Bezerra, A C B ^b  

^a UNIVERSIDADE CATÓLICA DE BRASÍLIA   (Brazil)

^b UNIVERSITY OF BRASILIA   (Brazil)

Author keywords

Cytokine; Elderly; Periodontics; Polymorphism

Indexed keywords

ADENINE; CYTOSINE; GUANINE; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

AGED; ALLELE; ALVEOLAR BONE LOSS; ARTICLE; CHRONIC PERIODONTITIS; DISEASE COURSE; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETICS; GENOTYPE; GINGIVA BLEEDING; HUMAN; IMMUNOLOGY; PERIODONTAL DISEASE; PROMOTER REGION;

ADENINE; AGED; ALLELES; ALVEOLAR BONE LOSS; CHRONIC PERIODONTITIS; CYTOSINE; DISEASE PROGRESSION; FEMALE; GENE FREQUENCY; GENOTYPE; GINGIVAL HEMORRHAGE; GUANINE; HUMANS; INTERLEUKIN-6; PERIODONTAL ATTACHMENT LOSS; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77149148419     PISSN: 07340664     EISSN: 17412358     Source Type: Journal    
DOI: 10.1111/j.1741-2358.2009.00291.x     Document Type: Article

References (34)

1. Takashiba S, Naruishi K. Gene polymorphisms in periodontal health and disease. Periodontol 2000 2006 40 : 94 106.
2. Kinane DF, Shiba H, Hart T. The genetic basis of periodontitis. Periodontol 2000 2005 39 : 91 117.
3. Kornman KS, Crane A, Wang HY et al. The interleukin-1 genotype as a severity factor in adult periodontal disease. J Clin Periodontol 1997 24 : 72 77.
4. Socransky SS, Haffajee AD, Cugini MA et al. Microbial complexes in subgingival plaque. J Clin Periodontol 1998 25 : 134 144.
5. Donati M, Berglundh T, Hytönen AM et al. Association of the -159 CD14 gene polymorphism and lack of association of the -308 TNFA and Q551R IL-4RA polymorphisms with severe chronic periodontitis in Swedish Caucasians. J Clin Periodontol 2005 32 : 474 479.
6. Taylor JJ, Preshaw PM, Donaldson PT. Cytokine gene polymorphism and immunoregulation in periodontal disease. Periodontol 2000 2004 35 : 158 182.
7. Loos BG, John RP, Laine ML. Identification of genetic risk factors for periodontitis and possible mechanisms of action. J Clin Periodontol 2005 32 (Suppl. 6 159 179.
8. Yoshie H, Kobayashi T, Tai H et al. The role of polymorphisms in periodontitis. Periodontol 2000 2007 43 : 102 132.
9. Trevilatto PC, Scarel-Caminaga RM, de Brito RB Jr. et al. Polymorphism at position -174 of IL-6 gene is associated with susceptibility to chronic periodontitis in a Caucasian Brazilian population. J Clin Periodontol 2003 30 : 438 442.
10. Shimada Y, Tai H, Endo M et al. Association of tumor necrosis factor receptor type 2 + 587 gene polymorphism with severe chronic periodontitis. J Clin Periodontol 2004 31 : 463 469.
11. Fassmann A, Izakovicova Holla L, Buckova D et al. Polymorphisms in the +252 (A/G) lymphotoxin-alpha and the -308 (A/G) tumor necrosis facto-alpha genes and susceptibility to chronic periodontitis in a Czech population. J Periodont Res 2003 38 : 394 399.
12. Folwaczny M, Glas J, Török HP et al. Lack of association between TNF α G-308A promoter polymorphism and periodontal disease. J Clin Periodontol 2004 31 : 449 453.
13. Soga Y, Nishimura F, Ohyama H et al. Tumor necrosis factor-alpha gene (TNFα) -1031/ -863, -857 single-nucleotide polymorphisms (SNPs) are associated with severe adult periodontitis in Japanese. J Clin Periodontol 2003 30 : 524 531.
14. Giunta S. Is inflammaging an auto(innate) immunity subclinical syndrome? Immun Ageing 2006 3 : 12.
15. Tervonen T, Raunio T, Kanuuttila M et al. Polymorphisms in the CD14 and IL-6 genes associated with periodontal disease. J Clin Periodontol 2007 34 : 377 383.
16. Duarte PM, de Oliveira MCG, Tambeli CH et al. Overexpression of interleukin-1β and interleukin-6 may play an important role in periodontal breakdown in type 2 diabetic patients. J Periodont Res 2007 42 : 377 381.
17. Karnikowski M, Córdova C, Oliveira RJ et al. Non-alcoholic fatty liver disease and metabolic syndrome in Brazilian middle-aged and older adults. Sao Paulo Med J 2007 125 : 333 337.
18. Moraes CF, Souza ER, Souza VC et al. A common polymorphism in the renin angiotensin system is associated with differential outcome of antihypertensive pharmacotherapy prescribed to Brazilian older women. Clin Chim Acta 2008 396 : 70 75.
19. Tonet AC, Karnikowski M, Moraes CF et al. Association between the -174 G/C promoter polymorphism of the interleukin-6 gene and cardiovascular disease risk factors in Brazilian older women. Braz J Med Biol Res 2008 41 : 47 53.
20. Ainamo J, Bay I. Problems and proposals for recording gingivitis and plaque. Int Dent J 1975 25 : 229 235.
21. Bourgeois D, Bouchard P, Mattout C. Epidemiology of periodontal status in dentate adults in France, 2002-2003. J Periodont Res 2007 42 : 219 227.
22. Armitage GC. Development of a classification system for periodontal diseases and conditions. Ann Periodontol 1999 4 : 1 6.
23. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988 16 : 1215.
24. Myliwska J, Bryl E, Foerster J, Myliwski A. Increase of Interleukin 6 and decrease of interleukin 2 production during aging process are influenced by the health status. Mech Ageing Dev 1998 100 : 313 328.
25. Mishto M, Santoro A, Bellavista E et al. Immunoproteasomes and immunosenescence. Ageing Res Rev 2003 2 : 419 432.
26. Górska R, Gregorek H, Kowalski J et al. Relationship between clinical parameters and cytokine profiles in inflamed gingival tissue and serum samples from patients with chronic periodontitis. J Clin Periodontol 2003 30 : 1046 1052.
27. Galbraith GM, Steed RB, Sanders JJ et al. Tumor necrosis factor alpha production by oral leukocytes: influence of tumor necrosis factor genotype. J Periodontol 1998 69 : 428 433.
28. Craandijk J, van Krugten MV, Verweij CL et al. Tumor necrosis factor-α gene polymorphisms in relation to periodontitis. J Clin Periodontol 2002 29 : 28 34.
29. Sakellari D, Katsares V, Georgiadou M et al. No correlation of five gene polymorphisms with periodontal conditions in a Greek population. J Clin Periodontol 2006 33 : 765 770.
30. Galbraith GM, Hendley TM, Sanders JJ et al. Polymorphic cytokine genotypes as markers of disease severity in adult periodontitis. J Clin Periodontol 1999 26 : 705 709.
31. Bonafe M, Olivieri F, Cavallone L et al. A gender-dependent genetic predisposition to produce high levels of IL-6 is detrimental for longevity. Eur J Immunol 2001 31 : 2357 2361.
32. Albandar JM. Global risk factors and risk indicators for periodontal diseases. Periodontol 2000 2002 29 : 177 206.
33. Mack F, Mojon P, Budtz-Jørgensen E et al. Caries and periodontal disease of the elderly in Pomerania, Germany: results of the Study of Health in Pomerania. Gerodontology 2004 21 : 27 36.
34. Nishimura I, Garret N. Impact of human genome project on treatment of frail and edentulous patients. Gerodontology 2004 21 : 3 9.