Med24 and Mdh2 are required for Drosophila larval salivary gland cell death

Developmental Dynamics

Volumn 239, Issue 3, 2010, Pages 954-964

  Wang, Lei ^a,b   Lam, Geanette ^a   Thummel, Carl S ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

Ecdysone signaling; Metabolism; Mitochondria; Programmed cell death

Indexed keywords

ADENOSINE TRIPHOSPHATE; CASPASE; MALATE DEHYDROGENASE;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CITRIC ACID CYCLE; CONTROLLED STUDY; DROSOPHILA; ENERGY YIELD; GENE; GENE CONTROL; GENE MUTATION; LARVA; MDH2 GENE; MED24 GENE; METAMORPHOSIS; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; SALIVARY GLAND; TRANSCRIPTION REGULATION;

ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; ANIMALS; CELL DEATH; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; LARVA; MALATE DEHYDROGENASE; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MUTATION; SALIVARY GLANDS; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION FACTORS; TRANSGENES;

EID: 77149125214     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.22213     Document Type: Article

References (40)

1. Abdelwahid E, Yokokura T, Krieser RJ, Balasundaram S, Fowle WH, White K. 2007. Mitochondrial disruption in Drosophila apoptosis. Dev Cell 12:793-806.
2. Akdemir F, Farkas R, Chen P, Juhasz G, Medved'ova L, Sass M, Wang L, Wang X, Chittaranjan S, Gorski SM, Rodriguez A, Abrams JM. 2006. Autophagy occurs upstream or parallel to the apoptosome during histolytic cell death. Development 133:1457-1465.
3. Andres AJ, Fletcher JC, Karim FD, Thummel CS. 1993. Molecular analysis of the initiation of insect metamorphosis: a comparative study of Drosophila ecdysteroid-regulated transcription. Dev Biol 160:388-404.
4. Andres AJ, Thummel CS. 1994. Methods for quantitative analysis of transcription in larvae and prepupae. In: Goldstein LSB, Fyrberg EA, editors. Drosophila melanogaster: practical uses in cell and molecular biology. New York: Academic Press. p 565-573.
5. Berry DL, Baehrecke EH. 2007. Growth arrest and autophagy are required for salivary gland cell degradation in Drosophila. Cell 131:1137-1148.
6. Boube M, Faucher C, Joulia L, Cribbs DL, Bourbon HM. 2000. Drosophila homologs of transcriptional mediator complex subunits are required for adult cell and segment identity specification. Genes Dev 14:2906-2917.
7. Boyd L, O'Toole E, Thummel CS. 1991. Patterns of E74A RNA and protein expression at the onset of metamorphosis in Drosophila. Development 112:981-995.
8. Chen P, Nordstrom W, Gish B, Abrams JM. 1996. grim, a novel cell death gene in Drosophila. Genes Dev 10:1773-1782.
9. Claros MG, Vincens P. 1996. Computational method to predict mitochondrially imported proteins and their targeting sequences. Eur J Biochem 241:779-786.
10. Daish TJ, Mills K, Kumar S. 2004. Drosophila caspase DRONC is required for specific developmental cell death pathways and stress-induced apoptosis. Dev Cell 7:909-915.
11. Danial NN, Korsmeyer SJ. 2004. Cell death: critical control points. Cell 116:205-219.
12. Dorstyn L, Colussi PA, Quinn LM, Richardson H, Kumar S. 1999. DRONC, an ecdysone-inducible Drosophila caspase. Proc Natl Acad Sci U S A 96:4307-4312.
13. Freel CD, Richardson DA, Thomenius MJ, Gan EC, Horn SR, Olson MR, Kornbluth S. 2008. Mitochondrial localization of Reaper to promote inhibitors of apoptosis protein degradation conferred by GH3 domain-lipid interactions. J Biol Chem 283:367-379.
14. Goyal G, Fell B, Sarin A, Youle RJ, Sriram V. 2007. Role of mitochondrial remodeling in programmed cell death in Drosophila melanogaster. Dev Cell 12:807-816.
15. Grether ME, Abrams JM, Agapite J, White K, Steller H. 1995. The head involution defective gene of Drosophila melanogaster functions in programmed cell death. Genes Dev 9:1694-1708.
16. Hay BA, Guo M. 2006. Caspase-dependent cell death in Drosophila. Annu Rev Cell Dev Biol 22:623-650.
17. Jacobson MD, Weil M, Raff MC. 1997. Programmed cell death in animal development. Cell 88:347-354.
18. Jiang C, Baehrecke EH, Thummel CS. 1997. Steroid regulated programmed cell death during Drosophila metamorphosis. Development 124:4673-4683.
19. Jiang C, Lamblin AF, Steller H, Thummel CS. 2000. A steroid-triggered transcriptional hierarchy controls salivary gland cell death during Drosophila metamorphosis. Mol Cell 5:445-455.
20. LaJeunesse DR, Buckner SM, Lake J, Na C, Pirt A, Fromson K. 2004. Three new Drosophila markers of intracellular membranes. Biotechniques 36:784-788, 790.
21. Lee CY, Baehrecke EH. 2001. Steroid regulation of autophagic programmed cell death during development. Development 128:1443-1455.
22. Lee CY, Simon CR, Woodard CT, Baehrecke EH. 2002. Genetic mechanism for the stage- and tissue-specific regulation of steroid triggered programmed cell death in Drosophila. Dev Biol 252:138-148.
23. Lee CY, Wendel DP, Reid P, Lam G, Thummel CS, Baehrecke EH. 2000. E93 directs steroid-triggered programmed cell death in Drosophila. Mol Cell 6:433-443.
24. Li TR, White KP. 2003. Tissue-specific gene expression and ecdysone-regulated genomic networks in Drosophila. Dev Cell 5:59-72.
25. Martin DN, Baehrecke EH. 2004. Caspases function in autophagic programmed cell death in Drosophila. Development 131:275-284.
26. McPhee CK, Baehrecke EH. 2009. Autophagy in Drosophila melanogaster. Biochim Biophys Acta 1793:1452-1460.
27. Mills K, Daish T, Harvey KF, Pfleger CM, Hariharan IK, Kumar S. 2006. The Drosophila melanogaster Apaf-1 homologue ARK is required for most, but not all, programmed cell death. J Cell Biol 172:809-815.
28. Rodriguez A, Oliver H, Zou H, Chen P, Wang X, Abrams JM. 1999. Dark is a Drosophila homologue of Apaf-1/CED-4 and functions in an evolutionarily conserved death pathway. Nat Cell Biol 1:272-279.
29. Schafer ZT, Kornbluth S. 2006. The apoptosome: physiological, developmental, and pathological modes of regulation. Dev Cell 10:549-561.
30. Scott RC, Schuldiner O, Neufeld TP. 2004. Role and regulation of starvationinduced autophagy in the Drosophila fat body. Dev Cell 7:167-178.
31. Voelker RA, Ohnishi S, Langley CH. 1979. Genetic and cytogenetic studies of the malate dehydrogenases of Drosophila melanogaster. Biochem Genet 17:947-956.
32. Wallace DC, Fan W. 2009. The pathophysiology of mitochondrial disease as modeled in the mouse. Genes Dev 23:1714-1736.
33. Wang L, Evans J, Andrews HK, Beckstead RB, Thummel CS, Bashirullah A. 2008. A genetic screen identifies new regulators of steroid-triggered programmed cell death in Drosophila. Genetics 180:269-281.
34. White K, Grether ME, Abrams JM, Young L, Farrell K, Steller H. 1994. Genetic control of programmed cell death in Drosophila. Science 264:677-683.
35. White K, Tahaoglu E, Steller H. 1996. Cell killing by the Drosophila gene reaper. Science 271:805-807.
36. Winoto A, Littman DR. 2002. Nuclear hormone receptors in T lymphocytes. Cell 109(suppl):S57-S66.
37. Yin VP, Thummel CS. 2004. A balance between the diap1 death inhibitor and reaper and hid death inducers controls steroid-triggered cell death in Drosophila. Proc Natl Acad Sci U S A 101:8022-8027.
38. Yin VP, Thummel CS. 2005. Mechanisms of steroid-triggered programmed cell death in Drosophila. Semin Cell Dev Biol 16:237-243.
39. Yin VP, Thummel CS, Bashirullah A. 2007. Down-regulation of inhibitor of apoptosis levels provides competence for steroid-triggered cell death. J Cell Biol 178:85-92.
40. Yu SY, Yoo SJ, Yang L, Zapata C, Srinivasan A, Hay BA, Baker NE. 2002. A pathway of signals regulating effector and initiator caspases in the developing Drosophila eye. Development 129:3269-3278.