Elevated blood urea nitrogen is an independent risk factor of prolonged intensive care unit stay due to acute necrotizing pancreatitis

Journal of Critical Care

Volumn 25, Issue 1, 2010, Pages 105-111

  Faisst, Maik ^a   Wellner, Ulrich F ^a   Utzolino, Stefan ^a   Hopt, Ulrich T ^a   Keck, Tobias ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Acute pancreatitis; Blood urea nitrogen (BUN); Intensive care unit; Predictive markers; Renal failure

Indexed keywords

NITROGEN; UREA;

ACUTE HEMORRHAGIC PANCREATITIS; ADULT; AGED; ARTICLE; DISEASE COURSE; DISEASE MARKER; FEMALE; HOSPITALIZATION; HUMAN; INTENSIVE CARE UNIT; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MORTALITY; PROGNOSIS; RETROSPECTIVE STUDY; RISK FACTOR; SURVIVAL RATE; UREA NITROGEN BLOOD LEVEL;

ADULT; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; BLOOD UREA NITROGEN; FEMALE; HOSPITAL MORTALITY; HUMANS; INTENSIVE CARE UNITS; LENGTH OF STAY; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PANCREATITIS, ACUTE NECROTIZING; PREDICTIVE VALUE OF TESTS; PROGNOSIS; RETROSPECTIVE STUDIES; RISK FACTORS;

EID: 77049086841     PISSN: 08839441     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcrc.2009.02.002     Document Type: Article

References (40)

1. Sigurdsson G. Intensive care management of acute pancreatitis. Dig Surg 11 (1994) 231-241
2. Steinberg W., and Tenner S. Acute pancreatitis. N Engl J Med 330 (1994) 1198-1210
3. Takeda K., Takada T., Kawarada Y., Hirata K., Mayumi T., Yoshida M., Sekimoto M., Hirota M., Kimura Y., Isaji S., Koizumi M., Otsuki M., and Matsuno S. Jpn guidelines for the management of acute pancreatitis: medical management of acute pancreatitis. J Hepatobiliary Pancreat Surg 13 (2006) 42-47
4. Ammori B.J. Role of the gut in the course of severe acute pancreatitis. Pancreas 26 (2003) 122-129
5. Ueda T.T.Y., Yasuda T., Matsumura N., Sawa H., Nakajima T., Ajiki T., Fujino Y., Suzuki Y., and Kuroda Y. Simple scoring system for the prediction of the prognosis of severe acute pancreatitis. Surgery 141 (2007) 51-58
6. Kes P., Vucicevic Z., Ratkovic-Gusic I., and Fotivec A. Acute renal failure complicating severe acute pancreatitis. Nephron 73 (1996) 488-489
7. Tran D.D., Oe P.L., de Fijter C.W., van der Meulen J., and Cuesta M.A. Acute renal failure in patients with acute pancreatitis: prevalence, risk factors, and outcome. Nephrol Dial Transplant 8 (1993) 1079-1084
8. Ranson J.H., Rifkind K.M., Roses D.F., Fink S.D., Eng K., and Spencer F.C. Prognostic signs and the role of operative management in acute pancreatitis. Surg Gynecol Obstet 139 (1974) 69-81
9. Blamey S.L., Imrie C.W., O'Neill J., Gilmour W.H., and Carter D.C. Prognostic factors in acute pancreatitis. Gut 25 (1984) 1340-1346
10. Buchler M.W., Gloor B., Muller C.A., Friess H., Seiler C.A., and Uhl W. Acute necrotizing pancreatitis: treatment strategy according to the status of infection. Ann Surg 232 (2000) 619-626
11. Mofidi R., Madhavan K.K., Garden O.J., and Parks R.W. An audit of the management of patients with acute pancreatitis against national standards of practice. Br J Surg (2007)
12. Le Mee J., Paye F., Sauvanet A., O'Toole D., Hammel P., Marty J., Ruszniewski P., and Belghiti J. Incidence and reversibility of organ failure in the course of sterile or infected necrotizing pancreatitis. Arch Surg 136 (2001) 1386-1390
13. Beger H.G., Bittner R., Block S., and Buchler M. Bacterial contamination of pancreatic necrosis. A prospective clinical study. Gastroenterology 91 (1986) 433-438
14. Zhu A.J., Shi J.S., and Sun X.J. Organ failure associated with severe acute pancreatitis. World J Gastroenterol 9 (2003) 2570-2573
15. Pitchumoni C.S., Patel N.M., and Shah P. Factors influencing mortality in acute pancreatitis: can we alter them?. J Clin Gastroenterol 39 (2005) 798-814
16. Gloor B., Muller C.A., Worni M., Martignoni M.E., Uhl W., and Buchler M.W. Late mortality in patients with severe acute pancreatitis. Br J Surg 88 (2001) 975-979
17. Doepel M., Eriksson J., Halme L., Kumpulainen T., and Hockerstedt K. Good long-term results in patients surviving severe acute pancreatitis. Br J Surg 80 (1993) 1583-1586
18. Bank S., Singh P., Pooran N., and Stark B. Evaluation of factors that have reduced mortality from acute pancreatitis over the past 20 years. J Clin Gastroenterol 35 (2002) 50-60
19. Wilson C., Heath D.I., and Imrie C.W. Prediction of outcome in acute pancreatitis: a comparative study of APACHE II, clinical assessment and multiple factor scoring systems. Br J Surg 77 (1990) 1260-1264
20. McKay C.J.I.C. Staging of acute pancreatitis. Is it important?. Surg Clin North Am 79 (1999) 733-743
21. Flint R.W.J. Early physiological response to intensive care as a clinically relevant approach to predicting outcome in severe acute pancreatitis. Arch Surg 139 (2004) 438-443
22. Frossard J.L.H.A., and Pastor C.M. New serum markers for the detection of severe acute pancreatitis in humans. Am J Respir Crit Care Med 164 (2001) 162-170
23. Werner J., Hartwig W., Uhl W., Muller C., and Buchler M.W. Useful markers for predicting severity and monitoring progression of acute pancreatitis. Pancreatology 3 (2003) 115-127
24. Johnson C.D., Abu-Hilal M., and Members of the British Acute Pancreatitis Study Group. Persistent organ failure during the first week as a marker of fatal outcome in acute pancreatitis. Gut (2004) 1340-1344
25. Flint R., Windsor J., and Bonham M. Trends in the management of severe acute pancreatitis: interventions and outcome. ANZ J Surg 74 (2004) 335-342
26. Halonen K.I., Pettila V., Leppaniemi A.K., Kemppainen E.A., Puolakkainen P.A., and Haapiainen R.K. Multiple organ dysfunction associated with severe acute pancreatitis. Crit Care Med 30 (2002) 1274-1279
27. Isenmann R., Rau B., and Beger H.G. Bacterial infection and extent of necrosis are determinants of organ failure in patients with acute necrotizing pancreatitis. Br J Surg 86 (1999) 1020-1024
28. De Waele J.J., Hoste E., Blot S.I., Hesse U., Pattyn P., de Hemptinne B., Decruyenaere J., Vogelaers D., and Colardyn F. Perioperative factors determine outcome after surgery for severe acute pancreatitis. Crit Care 8 (2004) R504-R511
29. Karimgani I.K.A., Porter A., Langevin R.E., and Banks P.A. Prognostic factors in sterile pancreatic necrosis. Gastroenterology 103 (1992) 1636-1640
30. Spitzer A.L., Barcia A.M., Schell M.T., Barber A., Norman J., Grendell J., and Harris H.W. Applying Ockham's razor to pancreatitis prognostication: a four-variable predictive model. Ann Surg 243 (2006) 380-388
31. Wu B.U., Johannes R.S., Sun X., Tabak Y., Conwell D.L., and Banks P.A. The early prediction of mortality in acute pancreatitis: a large population-based study. Gut (2008)
32. Arnell T.D.d.C., Chang L., Bongard F., and Stabile B.E. Admission factors can predict the need for ICU monitoring in gallstone pancreatitis. Am Surg (1996) 62815-62819
33. Kaya E.D.A., and Polat C. Evaluation of diagnostic findings and scoring systems in outcome prediction in acute pancreatitis. World J Gastroenterol 13 (2007) 3090-3094
34. Mayerle J.H.V., and Lerch M.M. Current management of acute pancreatitis. Nat Clin Pract Gastroenterol Hepatol 2 (2005) 473-483
35. Vega J., Karlezi R.A., and Galvez S. [Prolonged hospitalization in the intensive care unit: A worthless effort?]. Rev Med Chil 118 (1990) 643-648
36. Fragenholz P.J.F.-d.C.C., Harris N.S., Pelletier A.J., and Camargo C.A. Direct medical costs of acute pancreatitis hospitalizations in the United States. Panceras 35 (2007) 302-307
37. Soran A.C.L., Lee K.K.W., and Tisherman S.A. Outcome and quality of life of patients with acute pancreatitis requiring intensive care. J Surg Res 91 (2000) 89-94
38. Chalfin D.B.C.I.L., and Lambrinos J. The economics and cost-effectiveness of critical care medicine. Int Care Med 21 (1995) 952-961
39. Tenner S., Sica G., Hughes M., Noordhoek E., Feng S., Zinner M., and Banks P.A. Relationship of necrosis to organ failure in severe acute pancreatitis. Gastroenterology 113 (1997) 899-903
40. Malangoni M.A., and Martin A.S. Outcome of severe acute pancreatitis. Am J Surg 189 (2005) 273-277