Impaired secretion of carboxyl-terminal truncated factor VII due to an F7 nonsense mutation associated with FVII deficiency

Thrombosis Research

Volumn 125, Issue 3, 2010, Pages 262-266

  Tanaka, Ryoko ^a   Nakashima, Daisuke ^a   Suzuki, Atsuo ^a   Miyawaki, Yuhri ^a   Fujimori, Yuta ^a   Yamada, Takayuki ^a   Takagi, Akira ^a,b   Murate, Takashi ^a,b   Yamamoto, Koji ^c   Katsumi, Akira ^a   Matsushita, Tadashi ^a   Naoe, Tomoki ^a   Kojima, Tetsuhito ^a,c  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

^c NAGOYA UNIVERSITY HOSPITAL   (Japan)

Author keywords

C terminal truncation; F7 mutation; FVII deficiency; Impaired secretion

Indexed keywords

BLOOD CLOTTING FACTOR 7;

ADULT; ANIMAL CELL; ARTICLE; BLOOD CLOTTING FACTOR 7 DEFICIENCY; CARBOXY TERMINAL SEQUENCE; CASE REPORT; CHO CELL; DISEASE ASSOCIATION; ENDOPLASMIC RETICULUM; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE MUTATION; GOLGI COMPLEX; HUMAN; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; WESTERN BLOTTING;

ADULT; ANIMALS; CELL CULTURE TECHNIQUES; CHO CELLS; CODON, NONSENSE; CRICETINAE; CRICETULUS; CULTURE MEDIA; CULTURE MEDIA, SERUM-FREE; FACTOR VII; FACTOR VII DEFICIENCY; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PREGNANCY; RECOMBINANT PROTEINS; SEQUENCE ANALYSIS, DNA;

EID: 76949105054     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2009.09.014     Document Type: Article

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