Clinical relevance of thymidylate synthase (TS) activity for S-1-based chemotherapy in squamous cell carcinoma of the oral cavity

British Journal of Oral and Maxillofacial Surgery

Volumn 48, Issue 2, 2010, Pages 88-93

  Koga, Makoto ^a   Anegawa, Emiko ^a   Yoh, Junko ^a   Tsuyama, Haruki ^a   Sakaino, Hidenori ^a   Iwamoto, Osamu ^a   Koga, Chihiro ^a   Kusukawa, Jingo ^a  

^a KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Oral cancer; S 1; Squamous cell carcinoma; Thymidylate synthase

Indexed keywords

5 CHLORO 2,4 DIHYDROXYPYRIDINE PLUS OXONATE POTASSIUM PLUS TEGAFUR; THYMIDYLATE SYNTHASE;

ADULT; AGED; ARTICLE; CAUSE SPECIFIC SURVIVAL; DRUG EFFECT; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MOUTH CARCINOMA; MOUTH SQUAMOUS CELL CARCINOMA; TREATMENT OUTCOME; TUMOR CLASSIFICATION; UNSPECIFIED SIDE EFFECT;

ADULT; AGED; AGED, 80 AND OVER; ANTIMETABOLITES, ANTINEOPLASTIC; CARCINOMA, SQUAMOUS CELL; DRUG ADMINISTRATION SCHEDULE; DRUG COMBINATIONS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; KAPLAN-MEIERS ESTIMATE; MALE; MIDDLE AGED; MOUTH NEOPLASMS; OXONIC ACID; PROGNOSIS; RETROSPECTIVE STUDIES; STATISTICS, NONPARAMETRIC; TEGAFUR; THYMIDYLATE SYNTHASE;

EID: 76949099328     PISSN: 02664356     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bjoms.2009.05.010     Document Type: Article

References (23)

1. Koga M., Aoki M., Anegawa E., Tezuka M., Iwamoto O., Koga C., et al. Clinical evaluation of palliative chemotherapy with S-1 for oral cancer patients. Gan To Kagaku Ryoho 34 (2007) 719-723 [article in Japanese]
2. Shimizu T., Yamada Y., Yasui H., Shirao K., and Fukuoka M. Clinical application of immunoreactivity of dyhydropyrimidine dehydrogenase (DPD) in gastric schirrhous carcinoma treated with S-1, a new DPD inhibitory fluoropyrimidine. Anticancer Res 25 (2005) 2997-3001
3. Obara S., Yamamoto K., Hosogai N., and Yoshimura Y. Evaluation of TS-1 based treatment and expression of thymidylate synthase and dihydropyrimidine dehydrogenase on oral squamous cell carcinoma. Oral Oncol 41 (2005) 276-282
4. Habara K., Ajiki T., Kamigaki T., Nakamura T., and Kuroda Y. High expression of thymidylate synthase leads to resistance to 5-fluorouracil in biliary tract carcinoma in vitro. Jpn J Cancer Res 92 (2001) 1127-1132
5. Kawasaki G., Yoshimoto I., Yanamoto S., and Mizuno A. Thymidylate synthase and dihydropyrimidine dehydrogenase expression in oral squamous well carcinoma: an immunohistochemical and clinicopathologic study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 94 (2002) 717-723
6. Johnston P.G., Fisher E.R., Rockette H.E., Fisher B., Wolmark N., Drake J.C., et al. The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer. J Clin Oncol 12 (1994) 2640-2647
7. Terashima M., Irinoda T., Fujiwara H., Nakaya T., Takagane A., Abe K., et al. Role of thymidylate synthase and dyhydropyrimidine dehydrogenase in tumor progression and sensitivity to 5-fluorouracil in huma gastric cancer. Anticancer Res 22 (2002) 761-768
8. Majima H. Phase I and preliminary phase II study of coadministration of uracil and FT-207 (UFT therapy). Gan To Kagaku Ryoho 7 (1980) 1383-1387 [article in Japanese]
9. Shirasaka T., Shimamoto Y., Ohshimo H., Yamaguchi M., Kato T., Yonekura K., et al. Development of a novel form of an oral 5-fluorouracil derivative (S-1) directed to the potentiation of the tumor selective cytotoxicity of 5-fluorouracil by two biochemical modulators. Anticancer Drugs 7 (1998) 548-557
10. Inuyama Y., Kida A., Tsukuda M., Kohno N., and Satake B. Early phase II study of S-1 in patients with advanced head and neck cancer. Gan To Kagaku Ryoho 25 (1998) 1151-1158 [article in Japanese]
11. Inuyama Y., Kida A., Tsukuda M., Kohno N., and Satake B. Late phase II study of S-1 in patients with advanced head and neck cancer. Gan To Kagaku Ryoho 28 (2001) 1381-1390 [article in Japanese]
12. Kurebayashi J., Yamamoto Y., Udagawa K., Okubo S., Fukushima M., and Sonoo H. Establishment of enzyme-linked immunosorbent assays for thymidylate synthase and dyhydropyrimidine dehydrogenase in cancer tissues. Oncol Rep 11 (2004) 973-979
13. Shimosato Y., Oboshi S., and Baba K. Histological evaluation of effects of radiotherapy and chemotherapy for carcinomas. Jpn J Clin Oncol 1 (1971) 19-35 [article in Japanese]
14. Harada K., Supriano, Kawashima Y., Yoshida H., and Sato M. S-1 inhibits tumorigenicity and angiogenesis of human oral squamous cell carcinoma cells by suppressing expression of phosphorylated Akt, vascular endothelial growth factor and fibroblast growth factor-2. Int J Oncol 30 (2007) 365-374
15. Spears C.P., Shahinian A.H., Moran R.G., Heidelberger C., and Corbett T.H. In vitro kinetics of thymidylate synthetase inhibition of 5-fluorouracil-sensitive and -resistant murine colon adenocarcinomas. Cancer Res 42 (1982) 450-456
16. Shiga H., Heath E.I., Rasmussen A.A., Trock B., Johnston P.G., Forastiere A.A., et al. Prognostic value of p53, glutathione-S-transferase pi, and thymidylate synthase for neoadjuvant cisplatin-based chemotherapy in patients with advanced head and neck cancer. Clin Cancer Res 5 (1999) 4097-5104
17. Harada K., Kawashima Y., Yoshida H., and Sato M. Thymidylate synthase expression in oral squamous cell carcinoma predicts response to S-1. Oncol Rep 15 (2006) 1417-1423
18. Uehara M., Takahashi S., Takenaka A., Izumi H., Fujii K., Ikawa O., et al. Activities of thymidylate synthase and dihydropyrimidine dehydrogenase in patients with colorectal cancer. Gon To Kagaku Ryoho 28 (2001) 2035-2041 [article in Japanese]
19. Takechi T., Fujoka A., Matsushima E., and Fukushima M. Enhancement of antitumour activity of 5-fluorouracil (5_FU) by inhibiting dihydropyrimidine dehydrogenase activity (DPD) using 5-chloro-2,4-dihydropyridine (CDHP) in human tumour cells. Eur J Cancer 38 (2002) 1271-1277
20. Araki Y., Isomoto H., and Shirouzu K. Dihydropyrimidine dehydrogenase activity and thymidylate synthase level are associated with response to 5-fluorouracil in human colorectal cancer. Kurume Med J 48 (2001) 93-98
21. Fukui Y., Oka T., Nagayama S., Danenberg P., Danenberg K.D., and Fukushima M. Thymidylate synthase, dhydropyrimidine dehydrogenase, orotatephosphoribosyltransferase mRNA and protein expression levels in solid tumours in large scale population analysis. Int J Mol Med 22 (2008) 709-716
22. Adlard J.W., Richman S.D., Seymour M.T., and Quirke P. Prediction of the response of colorectal cancer to systemic therapy. Lancet Oncol 3 (2002) 75-82
23. Wada Y., Yoshida K., Suzuki T., Mizuiri H., Konishi K., Ukon K., et al. Synergistic effects of doxetaxel and S-1 by modulating the expression of metabolic enzymes of 5-fluorouracil in human gastric cancer cell lines. Int J Cancer 119 (2006) 783-791