-
1
-
-
0024539308
-
A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: A mid-atlantic oncology program study
-
Lokich JJ, Ahlgren JD, Gullo JJ, et al. A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: a mid-atlantic oncology program study. J Clin Oncol 1989; 7: 425-32.
-
(1989)
J Clin Oncol
, vol.7
, pp. 425-432
-
-
Lokich, J.J.1
Ahlgren, J.D.2
Gullo, J.J.3
-
2
-
-
0022179186
-
Long-term ambulatory treatment of metastatic colorectal adenocarcinoma by continuous intravenous infusion of 5-fluorouracil
-
Quebbeman E, Ausman R, Hansen R, et al. Long-term ambulatory treatment of metastatic colorectal adenocarcinoma by continuous intravenous infusion of 5-fluorouracil. J Surg Oncol 1985; 30: 60-5.
-
(1985)
J Surg Oncol
, vol.30
, pp. 60-65
-
-
Quebbeman, E.1
Ausman, R.2
Hansen, R.3
-
3
-
-
0024596670
-
Continuous systemic 5-fluorouracil (5-FU) infusion in advanced colorectal cancer. Results in 91 patients
-
Hansen R, Quebbeman E, Ausman R, et al. Continuous systemic 5-fluorouracil (5-FU) infusion in advanced colorectal cancer. Results in 91 patients. J Surg Oncol 1989; 40: 177-8.
-
(1989)
J Surg Oncol
, vol.40
, pp. 177-178
-
-
Hansen, R.1
Quebbeman, E.2
Ausman, R.3
-
4
-
-
0024580507
-
Treatment of colorectal cancer and other malignancies with continuous infusion of 5-fluorouracil
-
Barbounis VP, Kalofonos HP, Munro AJ, et al. Treatment of colorectal cancer and other malignancies with continuous infusion of 5-fluorouracil. Anticancer Res 1989; 9: 33-40.
-
(1989)
Anticancer Res
, vol.9
, pp. 33-40
-
-
Barbounis, V.P.1
Kalofonos, H.P.2
Munro, A.J.3
-
5
-
-
0029284818
-
Clinical trial of continuous infusion of 5-fluorouracil using an ambulatory pump for metastatic colorectal cancer
-
Yamao T, Shimada Y, Kondo H, et al. Clinical trial of continuous infusion of 5-fluorouracil using an ambulatory pump for metastatic colorectal cancer. Jpn J Clin Oncol 1995; 25: 46-50.
-
(1995)
Jpn J Clin Oncol
, vol.25
, pp. 46-50
-
-
Yamao, T.1
Shimada, Y.2
Kondo, H.3
-
6
-
-
0023735359
-
Continuous 5-fluorouracil (5-FU) infusion in advanced gastric carcinoma
-
Moynihan T, Hansen R, Anderson T, et al. Continuous 5-fluorouracil (5-FU) infusion in advanced gastric carcinoma. Am J Clin Oncol 1988; 11: 461-4.
-
(1988)
Am J Clin Oncol
, vol.11
, pp. 461-464
-
-
Moynihan, T.1
Hansen, R.2
Anderson, T.3
-
7
-
-
0024532587
-
Low dose continuous infusion 5-fluoroacil. Evaluation in advanced breast carcinoma
-
Huan S, Pazdur RT, Singhakowinta A, et al. Low dose continuous infusion 5-fluoroacil. Evaluation in advanced breast carcinoma. Cancer 1989; 63: 419-22.
-
(1989)
Cancer
, vol.63
, pp. 419-422
-
-
Huan, S.1
Pazdur, R.T.2
Singhakowinta, A.3
-
8
-
-
0023880296
-
Continuous 5-fluorouracil (5-FU) infusion in carcinoma of the pancreas
-
Hansen R, Quebbeman E, Ritch P, et al. Continuous 5-fluorouracil (5-FU) infusion in carcinoma of the pancreas. Am J Med Sci 1988; 295: 91-3.
-
(1988)
Am J Med Sci
, vol.295
, pp. 91-93
-
-
Hansen, R.1
Quebbeman, E.2
Ritch, P.3
-
9
-
-
0025845697
-
Continuous systemic 5-fluorouracil infusion in refractory prostatic cancer
-
Hansen R, Moynihan T, Beatty P, et al. Continuous systemic 5-fluorouracil infusion in refractory prostatic cancer. Urology 1991; 37: 358-61.
-
(1991)
Urology
, vol.37
, pp. 358-361
-
-
Hansen, R.1
Moynihan, T.2
Beatty, P.3
-
10
-
-
0021972067
-
Long-term, ambulatory, continuous intravenous infusion of 5-FU for the treatment of advanced adenocarcinomas
-
Caballero GA, Ausman RK, Quebbeman EJ, et al. Long-term, ambulatory, continuous intravenous infusion of 5-FU for the treatment of advanced adenocarcinomas. Cancer Treat Rep 1985; 69: 13-5.
-
(1985)
Cancer Treat Rep
, vol.69
, pp. 13-15
-
-
Caballero, G.A.1
Ausman, R.K.2
Quebbeman, E.J.3
-
11
-
-
0018744377
-
Mechanism of induction of gastrointestinal toxicity in the mouse by 5-fluorouracil, 5-fluorouridine and 5-fluoro-2′-deoxyuridine
-
Houghton JA, Houghton PJ, Wooten RS. Mechanism of induction of gastrointestinal toxicity in the mouse by 5-fluorouracil, 5-fluorouridine and 5-fluoro-2′-deoxyuridine. Cancer Res 1979; 39: 2406-13.
-
(1979)
Cancer Res
, vol.39
, pp. 2406-2413
-
-
Houghton, J.A.1
Houghton, P.J.2
Wooten, R.S.3
-
12
-
-
0027227591
-
Inhibition of oxonic acid of gastrointestinal toxicity of 5-fluorouracil without loss of its antitumor activity in rats
-
Shrasaka T, Shimamoto Y, Fukushima M. Inhibition of oxonic acid of gastrointestinal toxicity of 5-fluorouracil without loss of its antitumor activity in rats. Cancer Res 1993; 53: 4004-9.
-
(1993)
Cancer Res
, vol.53
, pp. 4004-4009
-
-
Shrasaka, T.1
Shimamoto, Y.2
Fukushima, M.3
-
13
-
-
0018222094
-
Clinical response and plasma levels of 5-fluorouracil in patients with colonic cancer treated drug infusion
-
Hillcoat BL, McCulloch PB, Figueredo AT, et al. Clinical response and plasma levels of 5-fluorouracil in patients with colonic cancer treated drug infusion. Br J Cancer 1978; 38: 719-24.
-
(1978)
Br J Cancer
, vol.38
, pp. 719-724
-
-
Hillcoat, B.L.1
McCulloch, P.B.2
Figueredo, A.T.3
-
14
-
-
0017811782
-
The pharmacokinetics of high-dose continuous 5-flourouracil infusions
-
Gudauskas G, Goldie JH. The pharmacokinetics of high-dose continuous 5-flourouracil infusions. Proc Am Ass Cancer Res 1978; 19: 230.
-
(1978)
Proc Am Ass Cancer Res
, vol.19
, pp. 230
-
-
Gudauskas, G.1
Goldie, J.H.2
-
16
-
-
0019452812
-
Modulation of 5-fluourouracil toxicity by allopurinol in man
-
Howell SB, Wung WE, Taetle R, et al. Modulation of 5-fluourouracil toxicity by allopurinol in man. Cancer 1981; 48: 1281-9.
-
(1981)
Cancer
, vol.48
, pp. 1281-1289
-
-
Howell, S.B.1
Wung, W.E.2
Taetle, R.3
-
17
-
-
0020071111
-
A rapid high-performance liquid chromatographic method for quantitation of 5-fluorouracil in plasma after continuing intravenous infusion
-
Sampson DC, Fox RM, Tattersall MHN, et al. A rapid high-performance liquid chromatographic method for quantitation of 5-fluorouracil in plasma after continuing intravenous infusion. Ann Clin Biochem 1982; 19: 125-8.
-
(1982)
Ann Clin Biochem
, vol.19
, pp. 125-128
-
-
Sampson, D.C.1
Fox, R.M.2
Tattersall, M.H.N.3
-
18
-
-
0019993424
-
Cerebrospinal fluid versus serum concentrations of 5-FU, allopurinol, and oxipurinol during treatment of metastatic brain cancer with 5-FU infusion, allopurinol, and radiation
-
Hornbeck CL, Floyd RA, Byfield JE, et al. Cerebrospinal fluid versus serum concentrations of 5-FU, allopurinol, and oxipurinol during treatment of metastatic brain cancer with 5-FU infusion, allopurinol, and radiation. Cancer Treat Rep 1982; 66: 571-3.
-
(1982)
Cancer Treat Rep
, vol.66
, pp. 571-573
-
-
Hornbeck, C.L.1
Floyd, R.A.2
Byfield, J.E.3
-
19
-
-
0021846746
-
Continuous 5-day regional chemotherapy by 5-fluourouracil in colon carcinoma: Pharmacokinetic evaluation
-
Boublil JL, Milano G, Khater R, et al. Continuous 5-day regional chemotherapy by 5-fluourouracil in colon carcinoma: pharmacokinetic evaluation. Br J Cancer 1985; 52: 15-20.
-
(1985)
Br J Cancer
, vol.52
, pp. 15-20
-
-
Boublil, J.L.1
Milano, G.2
Khater, R.3
-
20
-
-
0022520957
-
Plasma pharmacokinetics of 5-FU given continuous infusion with allopurinal
-
Erlichman C, Fine S, Elhakim T. Plasma pharmacokinetics of 5-FU given continuous infusion with allopurinal. Cancer Treat Rep 1986; 70: 903-4.
-
(1986)
Cancer Treat Rep
, vol.70
, pp. 903-904
-
-
Erlichman, C.1
Fine, S.2
Elhakim, T.3
-
21
-
-
0023876379
-
Circadian rhythm-varing plasma concentration of 5-fluorouracil during five day continuous venous infusion at a constant rate in cancer patients
-
Petit E, Milano G, Levi F. Circadian rhythm-varing plasma concentration of 5-fluorouracil during five day continuous venous infusion at a constant rate in cancer patients. Cancer Res 1988; 48: 1676-9.
-
(1988)
Cancer Res
, vol.48
, pp. 1676-1679
-
-
Petit, E.1
Milano, G.2
Levi, F.3
-
22
-
-
0025058867
-
Relationship between dihydropyrimidine dehydrogenase activity and plasma 5-fluourouracil levels with evidence for circadian variation of enzyme activity and plasma levels in patients receiving 5-fluourouracil by protracted continuous infusion
-
Harris BE, Song R, Soong S, et al. Relationship between dihydropyrimidine dehydrogenase activity and plasma 5-fluourouracil levels with evidence for circadian variation of enzyme activity and plasma levels in patients receiving 5-fluourouracil by protracted continuous infusion. Cancer Res 1990; 50: 197-201.
-
(1990)
Cancer Res
, vol.50
, pp. 197-201
-
-
Harris, B.E.1
Song, R.2
Soong, S.3
-
23
-
-
0027932318
-
Spontaneous or imposed circadian changes in plasma concentrations of 5-fluorouracil coadministered with folinic acid and oxaliplatin: Relationship with mucosal toxicity in patients with cancer
-
Metzger G, Massari C, Etienne M-C, et al. Spontaneous or imposed circadian changes in plasma concentrations of 5-fluorouracil coadministered with folinic acid and oxaliplatin: relationship with mucosal toxicity in patients with cancer. Clin Pharmacol Ther 1994; 56: 190-201.
-
(1994)
Clin Pharmacol Ther
, vol.56
, pp. 190-201
-
-
Metzger, G.1
Massari, C.2
Etienne, M.-C.3
-
24
-
-
0024267360
-
Circadian rhythm of rat liver dihydropyrimidine dehydrogenase. Possible relevance to fluoropyrimidine chemotherapy
-
Harris BE, Song R, He Y-J, et al. Circadian rhythm of rat liver dihydropyrimidine dehydrogenase. Possible relevance to fluoropyrimidine chemotherapy. Biochem Pharmacol 1988; 37: 4759-62.
-
(1988)
Biochem Pharmacol
, vol.37
, pp. 4759-4762
-
-
Harris, B.E.1
Song, R.2
He, Y.-J.3
-
25
-
-
0024833789
-
Effects of the plasma concentration of 5-fluorouracil and the duration of continuous venous infusion of 5-fluorouracil with an inhibitor of 5-fluorouracil degradation on Yoshida sarcomas in rats
-
Fujii S, Shimamoto Y, Shirasaka T, et al. Effects of the plasma concentration of 5-fluorouracil and the duration of continuous venous infusion of 5-fluorouracil with an inhibitor of 5-fluorouracil degradation on Yoshida sarcomas in rats. Jpn J Cancer Res 1989; 80: 167-72.
-
(1989)
Jpn J Cancer Res
, vol.80
, pp. 167-172
-
-
Fujii, S.1
Shimamoto, Y.2
Shirasaka, T.3
-
26
-
-
0023187085
-
Clinical pharmacokinetics of 5-fluorouracil and it metabolites in plasma, urine and bile
-
Heggie GD, Sommadossi J-P, Cross DS, et al. Clinical pharmacokinetics of 5-fluorouracil and it metabolites in plasma, urine and bile. Cancer Res 1987; 47: 2203-06.
-
(1987)
Cancer Res
, vol.47
, pp. 2203-2206
-
-
Heggie, G.D.1
Sommadossi, J.-P.2
Cross, D.S.3
-
27
-
-
0023250474
-
Inhibitory effects of pyrimidine, Barbituric acid and pyridine derivatives on 5-fluourouracil degradation in rat liver extracts
-
Tatsumi K, Fukushima M, Shirasaka T, et al. Inhibitory effects of pyrimidine, Barbituric acid and pyridine derivatives on 5-fluourouracil degradation in rat liver extracts. Gann 1987; 78: 748-55.
-
(1987)
Gann
, vol.78
, pp. 748-755
-
-
Tatsumi, K.1
Fukushima, M.2
Shirasaka, T.3
-
28
-
-
0014200274
-
Analogs of pyrimidine nucleosides, I. N-(a-furanidyl) derivatives of natural pyrimidine based and their antimetabolites
-
Hiller SA, Zhuk PA, Lidak MJ. Analogs of pyrimidine nucleosides, I. N-(a-furanidyl) derivatives of natural pyrimidine based and their antimetabolites. Dokl Akad Kauk SSSR 1967; 176: 332-5.
-
(1967)
Dokl Akad Kauk SSSR
, vol.176
, pp. 332-335
-
-
Hiller, S.A.1
Zhuk, P.A.2
Lidak, M.J.3
-
29
-
-
0018216763
-
Effect of uracil and it derivatives on antitumor activity of 5-fluourouracil and 1-(2-tetrahydrofuryl)-5-flourouracil
-
Fujii S, Ikenaka K, Fukishima M, et al. Effect of uracil and it derivatives on antitumor activity of 5-fluourouracil and 1-(2-tetrahydrofuryl)-5-flourouracil. Gann 1978; 69: 763-72.
-
(1978)
Gann
, vol.69
, pp. 763-772
-
-
Fujii, S.1
Ikenaka, K.2
Fukishima, M.3
-
30
-
-
0018645911
-
Effect of uracil on metabolism of 5-fluorouracil in vitro
-
Ikenaka K, Shirasaka T, Kitano S, et al. Effect of uracil on metabolism of 5-fluorouracil in vitro. Jpn J Cancer Res 1979; 70: 353-9.
-
(1979)
Jpn J Cancer Res
, vol.70
, pp. 353-359
-
-
Ikenaka, K.1
Shirasaka, T.2
Kitano, S.3
-
31
-
-
0027534425
-
Dihydropyrimidine dehydrogenase activity in cancer patients
-
Fleming RA, Milano GA, Gaspard MH, et al. Dihydropyrimidine dehydrogenase activity in cancer patients. Eur J cancer 1993; 29A: 740-44.
-
(1993)
Eur J Cancer
, vol.29 A
, pp. 740-744
-
-
Fleming, R.A.1
Milano, G.A.2
Gaspard, M.H.3
-
32
-
-
0028073326
-
Predictive value of thymidylate synthetase and dihydropyrimidine dehydrogenase
-
Peters GJ, van der Wilt CL, van Groeningen CJ. Predictive value of thymidylate synthetase and dihydropyrimidine dehydrogenase. Eur J Cancer 1994; 30A: 1408-11.
-
(1994)
Eur J Cancer
, vol.30 A
, pp. 1408-1411
-
-
Peters, G.J.1
Van Der Wilt, C.L.2
Van Groeningen, C.J.3
-
33
-
-
0028097137
-
A role for dihydropyrimidine dehydrogenase and thymidylate synthase in tumor sensitivity to flurouracil
-
Beck A, Etienne MC, Che'radame S, et al. A role for dihydropyrimidine dehydrogenase and thymidylate synthase in tumor sensitivity to flurouracil. Eur J Cancer 1994; 30A: 1517-22.
-
(1994)
Eur J Cancer
, vol.30 A
, pp. 1517-1522
-
-
Beck, A.1
Etienne, M.C.2
Che'radame, S.3
-
34
-
-
0028049685
-
Inhibition of fluorouracil catabolism in cancer patients by the antiviral agent (E)-5-(2-bromovinyl)-2′-deoxyuridine
-
Keizer HJ, De Bruijn EA, Tjaden UR, et al. Inhibition of fluorouracil catabolism in cancer patients by the antiviral agent (E)-5-(2-bromovinyl)-2′-deoxyuridine. J Cancer Res Clin Oncol 1994; 120: 545-9.
-
(1994)
J Cancer Res Clin Oncol
, vol.120
, pp. 545-549
-
-
Keizer, H.J.1
De Bruijn, E.A.2
Tjaden, U.R.3
-
35
-
-
0000632425
-
Initial phase I trial of the dihydropyrimidine dehydrogenase inactivator 5-ethynyluracil (776C85) plus 5-fluorouracil
-
abstr 368
-
Burris H, Schilsky R, Fields S, et al. Initial phase I trial of the dihydropyrimidine dehydrogenase inactivator 5-ethynyluracil (776C85) plus 5-fluorouracil. Am Soc Clin Oncol Proc 1995; 14: 171 (abstr 368).
-
(1995)
Am Soc Clin Oncol Proc
, vol.14
, pp. 171
-
-
Burris, H.1
Schilsky, R.2
Fields, S.3
-
36
-
-
0009691107
-
5-Ethynyluracil (776C85), an inhibitor of dihydropyrimidine dehydrogenase (DPD), permits reliable oral dosing of 5-fluorouracil (5-FU) and prolongs its half-life (1/2 T)
-
abstr 1478
-
Adjei AA, Doucette M, Spector T, et al. 5-Ethynyluracil (776C85), an inhibitor of dihydropyrimidine dehydrogenase (DPD), permits reliable oral dosing of 5-fluorouracil (5-FU) and prolongs its half-life (1/2 T). Am Soc Clin Oncol Proc 1995; 14: 459 (abstr 1478).
-
(1995)
Am Soc Clin Oncol Proc
, vol.14
, pp. 459
-
-
Adjei, A.A.1
Doucette, M.2
Spector, T.3
-
37
-
-
0026701936
-
Mechanism-based inactivation of dihydropyrimidine dehydrogenase by 5-ethyluracil
-
Porter DJT, Chestnut WG, Merrill BM, et al. Mechanism-based inactivation of dihydropyrimidine dehydrogenase by 5-ethyluracil. J Biol Chem 1992; 267: 5236-42.
-
(1992)
J Biol Chem
, vol.267
, pp. 5236-5242
-
-
Porter, D.J.T.1
Chestnut, W.G.2
Merrill, B.M.3
-
38
-
-
0018888144
-
Allopurinol modulation of the toxicity and antitumor activity of 5-fluorouracil
-
Schwartz PM, Dunigan JM, Marsh JC, et al. Allopurinol modulation of the toxicity and antitumor activity of 5-fluorouracil. Cancer Res 1980; 40: 1885-9.
-
(1980)
Cancer Res
, vol.40
, pp. 1885-1889
-
-
Schwartz, P.M.1
Dunigan, J.M.2
Marsh, J.C.3
-
39
-
-
0019983332
-
5-FU and allopurinol: Toxicity modulation and phase II results in colon cancer
-
Kroener JF, Saleh F, Howell SB. 5-FU and allopurinol: toxicity modulation and phase II results in colon cancer. Cancer Treat Rep 1982, 66: 1133-7.
-
(1982)
Cancer Treat Rep
, vol.66
, pp. 1133-1137
-
-
Kroener, J.F.1
Saleh, F.2
Howell, S.B.3
-
40
-
-
0022005048
-
A controlled trial of the effect of 4-hydroxypyrazolo-pyrimidine (allopurinol) on the toxicity of a single bolus dose of 5-fluorouracil
-
Wooley PV, Ayoob MT, Smith FP, et al. A controlled trial of the effect of 4-hydroxypyrazolo-pyrimidine (allopurinol) on the toxicity of a single bolus dose of 5-fluorouracil. J Clin Oncol 1985; 3: 103-9.
-
(1985)
J Clin Oncol
, vol.3
, pp. 103-109
-
-
Wooley, P.V.1
Ayoob, M.T.2
Smith, F.P.3
|