111In- or 99mTc-labeled recombinant VEGF bioconjugates: in vitro evaluation of their cytotoxicity on porcine aortic endothelial cells overexpressing Flt-1 receptors

Nuclear Medicine and Biology

Volumn 37, Issue 2, 2010, Pages 105-115

  Chan, Conrad ^a   Cai, Zhongli ^a   Su, Ruifen ^a   Reilly, Raymond M ^a,b,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

111In; 99mTc; Angiogenesis; Nuclear localization sequence, NLS; Vascular endothelial growth factor

Indexed keywords

DOUBLE STRANDED DNA; HISTIDINE; HISTONE H2A; LYSINE; METHANOL; PENTETIC ACID; RADIOPHARMACEUTICAL AGENT; RECOMBINANT VASCULOTROPIN; RECOMBINANT VASCULOTROPIN IN 111; RECOMBINANT VASCULOTROPIN TC 99M; TRICARBOXYLIC ACID; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 1; INDIUM; PEPTIDE; RECOMBINANT PROTEIN; TECHNETIUM; VASCULOTROPIN A;

AFFINITY CHROMATOGRAPHY; ANIMAL CELL; ARTICLE; AUGER ELECTRON SPECTROSCOPY; CELL SURVIVAL; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DERIVATIZATION; DOUBLE STRANDED DNA BREAK; DRUG SYNTHESIS; ENDOTHELIUM CELL; GENETIC TRANSFECTION; HUMAN; IMMUNOFLUORESCENCE; IN VITRO STUDY; ISOTOPE LABELING; MONTE CARLO METHOD; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PICHIA PASTORIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; RADIATION DOSE; RECEPTOR AFFINITY; RECEPTOR UPREGULATION; SWINE; ACTIVE TRANSPORT; AMINO ACID SEQUENCE; ANIMAL; AORTA; BIOLOGICAL MODEL; BIOSYNTHESIS; CELL NUCLEUS; CHEMISTRY; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION; GENETICS; METABOLISM; PICHIA; RADIATION EXPOSURE;

ACTIVE TRANSPORT, CELL NUCLEUS; AMINO ACID SEQUENCE; ANIMALS; AORTA; CELL NUCLEUS; CELL SURVIVAL; DNA BREAKS, DOUBLE-STRANDED; ENDOTHELIAL CELLS; GENE EXPRESSION; HUMANS; INDIUM RADIOISOTOPES; MODELS, BIOLOGICAL; MONTE CARLO METHOD; PENTETIC ACID; PEPTIDES; PICHIA; RADIATION DOSAGE; RECOMBINANT PROTEINS; SWINE; TECHNETIUM; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1;

EID: 76949098852     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2009.10.001     Document Type: Article

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