C-kit-targeted imaging of gastrointestinal stromal tumor using radiolabeled anti-c-kit monoclonal antibody in a mouse tumor model

Nuclear Medicine and Biology

Volumn 37, Issue 2, 2010, Pages 179-187

  Sogawa, Chizuru ^a   Tsuji, Atsushi B ^a   Sudo, Hitomi ^a,b   Sugyo, Aya ^a   Yoshida, Chisato ^a,c   Odaka, Kenichi ^a   Uehara, Tomoya ^c   Arano, Yasushi ^c   Koizumi, Mitsuru ^a   Saga, Tsuneo ^a  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^b JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c CHIBA UNIVERSITY   (Japan)

Author keywords

C kit; Gastrointestinal stromal tumor; Monoclonal antibody; Mouse tumor model

Indexed keywords

MONOCLONAL ANTIBODY 12A8 I 125; MONOCLONAL ANTIBODY 12A8 IN 111; RADIOISOTOPE; STEM CELL FACTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; CELL CLONE; CELL STRAIN HEK293; COMPETITIVE INHIBITION; CONTROLLED STUDY; DEHALOGENATION; DISSOCIATION CONSTANT; DRUG DISTRIBUTION; DRUG SCREENING; DRUG TARGETING; EXPRESSION VECTOR; GASTROINTESTINAL STROMAL TUMOR; GENE EXPRESSION REGULATION; GENE MUTATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INOCULATION; INTERNALIZATION; ISOTOPE LABELING; MALE; MOLECULAR IMAGING; MOUSE; NONHUMAN; NUDE MOUSE; RADIOACTIVITY; SCINTIGRAPHY; SENSITIVITY AND SPECIFICITY; TUMOR CELL; TUMOR XENOGRAFT;

ANIMALS; ANTIBODIES, MONOCLONAL; BINDING, COMPETITIVE; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; GASTROINTESTINAL STROMAL TUMORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INDIUM RADIOISOTOPES; IODINE RADIOISOTOPES; MALE; MICE; MOLECULAR IMAGING; MUTATION; PROTO-ONCOGENE PROTEINS C-KIT; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 76949097633     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2009.10.008     Document Type: Article

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