-
1
-
-
0004321816
-
-
For general reviews on Buruli ulcer for example see:. Ravinglione M. (Ed), World Health Organization, Geneva, Switzerland
-
For general reviews on Buruli ulcer for example see:. Asiedu K., and Scherpbier R. In: Ravinglione M. (Ed). Buruli ulcer: Mycobacterium ulcerans infection (2000), World Health Organization, Geneva, Switzerland
-
(2000)
Buruli ulcer: Mycobacterium ulcerans infection
-
-
Asiedu, K.1
Scherpbier, R.2
-
2
-
-
0141537208
-
-
van der Werf T.S., Stinear T., Stienstra Y., van der Graaf W.T.A., and Small P.L. Lancet 362 (2003) 1062
-
(2003)
Lancet
, vol.362
, pp. 1062
-
-
van der Werf, T.S.1
Stinear, T.2
Stienstra, Y.3
van der Graaf, W.T.A.4
Small, P.L.5
-
3
-
-
19344362304
-
-
Johnson P.D.R., Stinear T., Small P.L.C., Pluschke G., Merritt R.W., Portaels F., Huygen K., Hayman J.A., and Asiedu K. PLoS Med. 2 (2005) e108
-
(2005)
PLoS Med.
, vol.2
-
-
Johnson, P.D.R.1
Stinear, T.2
Small, P.L.C.3
Pluschke, G.4
Merritt, R.W.5
Portaels, F.6
Huygen, K.7
Hayman, J.A.8
Asiedu, K.9
-
4
-
-
26944484811
-
-
van der Werf T.S., Stienstra Y., Johnson R.C., Phillips R., Adjei O., Fleischer B., Wansbrough-Jones M.H., Johnson P.D.R., Portaels F., van der Graaf W.T.A., and Asiedu K. Bull. World Health Org. 83 (2005) 785
-
(2005)
Bull. World Health Org.
, vol.83
, pp. 785
-
-
van der Werf, T.S.1
Stienstra, Y.2
Johnson, R.C.3
Phillips, R.4
Adjei, O.5
Fleischer, B.6
Wansbrough-Jones, M.H.7
Johnson, P.D.R.8
Portaels, F.9
van der Graaf, W.T.A.10
Asiedu, K.11
-
5
-
-
44249084709
-
-
Hong H., Demangel C., Pidot S.J., Leadlay P.F., and Stinear T. Nat. Prod. Rep. (2008) 447
-
(2008)
Nat. Prod. Rep.
, pp. 447
-
-
Hong, H.1
Demangel, C.2
Pidot, S.J.3
Leadlay, P.F.4
Stinear, T.5
-
7
-
-
0033524996
-
-
George K.M., Chatterjee D., Gunawardana G., Welty D., Hayman J., Lee R., and Small P.L.C. Science 283 (1999) 854
-
(1999)
Science
, vol.283
, pp. 854
-
-
George, K.M.1
Chatterjee, D.2
Gunawardana, G.3
Welty, D.4
Hayman, J.5
Lee, R.6
Small, P.L.C.7
-
8
-
-
0033618117
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-
For the gross-structure of mycolactone A/B, see:
-
For the gross-structure of mycolactone A/B, see:. Gunawardana G., Chatterjee D., George K.M., Brennan P., Whittern D., and Small P.L.C. J. Am. Chem. Soc. 121 (1999) 6092
-
(1999)
J. Am. Chem. Soc.
, vol.121
, pp. 6092
-
-
Gunawardana, G.1
Chatterjee, D.2
George, K.M.3
Brennan, P.4
Whittern, D.5
Small, P.L.C.6
-
9
-
-
0034803598
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-
For the stereochemistry of mycolactone A/B, see:
-
For the stereochemistry of mycolactone A/B, see:. Benowitz A.B., Fidanze S., Small P.L.C., and Kishi Y. J. Am. Chem. Soc. 123 (2001) 5128
-
(2001)
J. Am. Chem. Soc.
, vol.123
, pp. 5128
-
-
Benowitz, A.B.1
Fidanze, S.2
Small, P.L.C.3
Kishi, Y.4
-
10
-
-
0035904418
-
-
Fidanze S., Song F., Szlosek-Pinaud M., Small P.L.C., and Kishi Y. J. Am. Chem. Soc. 123 (2001) 10117
-
(2001)
J. Am. Chem. Soc.
, vol.123
, pp. 10117
-
-
Fidanze, S.1
Song, F.2
Szlosek-Pinaud, M.3
Small, P.L.C.4
Kishi, Y.5
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11
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0037149026
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-
For the total synthesis of mycolactone A/B. See: and Tetrahedron, 2007, 63, 5739
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For the total synthesis of mycolactone A/B. See:. Song F., Fidanze S., Benowitz A.B., and Kishi Y. Org. Lett. 4 (2002) 647 and Tetrahedron, 2007, 63, 5739
-
(2002)
Org. Lett.
, vol.4
, pp. 647
-
-
Song, F.1
Fidanze, S.2
Benowitz, A.B.3
Kishi, Y.4
-
13
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0037306541
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For mycolactone C, see: (a) the isolation and gross-structure:
-
For mycolactone C, see: (a) the isolation and gross-structure:. Mve-Obiang A., Lee R.E., Portaels F., and Small P.L.C. Infect. Immun. 71 (2003) 774
-
(2003)
Infect. Immun.
, vol.71
, pp. 774
-
-
Mve-Obiang, A.1
Lee, R.E.2
Portaels, F.3
Small, P.L.C.4
-
14
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12344259565
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-
the stereochemistry and total synthesis:
-
the stereochemistry and total synthesis:. Judd T.C., Bischoff A., Kishi Y., Adusumilli S., and Small P.L.C. Org. Lett. 6 (2004) 4901
-
(2004)
Org. Lett.
, vol.6
, pp. 4901
-
-
Judd, T.C.1
Bischoff, A.2
Kishi, Y.3
Adusumilli, S.4
Small, P.L.C.5
-
15
-
-
21044436769
-
-
Hong H., Spencer J.B., Porter J.L., Leadlay P.F., and Stinear T. ChemBioChem 6 (2005) 643
-
(2005)
ChemBioChem
, vol.6
, pp. 643
-
-
Hong, H.1
Spencer, J.B.2
Porter, J.L.3
Leadlay, P.F.4
Stinear, T.5
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16
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33750451251
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For mycolactone F, see: (a) isolation and gross-structure:
-
For mycolactone F, see: (a) isolation and gross-structure:. Ranger B.S., Mahrous E.A., Mosi L., Adusumilli S., Lee R.E., Colorni A., Rhodes M., and Small P.L.C. Infect. Immun. 74 (2006) 6037
-
(2006)
Infect. Immun.
, vol.74
, pp. 6037
-
-
Ranger, B.S.1
Mahrous, E.A.2
Mosi, L.3
Adusumilli, S.4
Lee, R.E.5
Colorni, A.6
Rhodes, M.7
Small, P.L.C.8
-
17
-
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36849041020
-
-
Hong H., Stinear T., Porter J., Demangel C., and Leadlay P.F. ChemBioChem 8 (2007) 2043
-
(2007)
ChemBioChem
, vol.8
, pp. 2043
-
-
Hong, H.1
Stinear, T.2
Porter, J.3
Demangel, C.4
Leadlay, P.F.5
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18
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39049083577
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stereochemistry and total synthesis of mycolactone F isolated from the saltwater fish pathogen M. marinum:
-
stereochemistry and total synthesis of mycolactone F isolated from the saltwater fish pathogen M. marinum:. Kim H.-J., and Kishi Y. J. Am. Chem. Soc. 130 (2008) 1842
-
(2008)
J. Am. Chem. Soc.
, vol.130
, pp. 1842
-
-
Kim, H.-J.1
Kishi, Y.2
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19
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72649103927
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stereochemistry and total synthesis of mycolactone F isolated from the freshwater fish pathogen M. marinum:
-
stereochemistry and total synthesis of mycolactone F isolated from the freshwater fish pathogen M. marinum:. Kim H.-J., Jackson K.L., Kishi Y., Williamson H.R., Mosi L., and Small P.L.C. Chem. Commun. (2009) 7402
-
(2009)
Chem. Commun.
, pp. 7402
-
-
Kim, H.-J.1
Jackson, K.L.2
Kishi, Y.3
Williamson, H.R.4
Mosi, L.5
Small, P.L.C.6
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20
-
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3042739430
-
-
Trott K.A., Stacy B.A., Lifland B.D., Diggs H.E., Harland R.M., Khokha M.K., Grammer T.A., and Parker J.M. Comp. Med. 54 (2004) 309
-
(2004)
Comp. Med.
, vol.54
, pp. 309
-
-
Trott, K.A.1
Stacy, B.A.2
Lifland, B.D.3
Diggs, H.E.4
Harland, R.M.5
Khokha, M.K.6
Grammer, T.A.7
Parker, J.M.8
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21
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25144433250
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For mycolactone E, see: (a) isolation and gross-structure:
-
For mycolactone E, see: (a) isolation and gross-structure:. Hong H., Stinear T., Skelton P., Spencer J.B., and Leadlay P.F. Chem. Commun. (2005) 4306
-
(2005)
Chem. Commun.
, pp. 4306
-
-
Hong, H.1
Stinear, T.2
Skelton, P.3
Spencer, J.B.4
Leadlay, P.F.5
-
22
-
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21144473378
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-
and
-
and. Mve-Obiang A., Lee R.E., Umstot E.S., Trott K.A., Grammer T.C., Parker J.M., Ranger B.S., Grainger R., Mahrous E.A., and Small P.L.C. Infect. Immun. 73 (2005) 3307
-
(2005)
Infect. Immun.
, vol.73
, pp. 3307
-
-
Mve-Obiang, A.1
Lee, R.E.2
Umstot, E.S.3
Trott, K.A.4
Grammer, T.C.5
Parker, J.M.6
Ranger, B.S.7
Grainger, R.8
Mahrous, E.A.9
Small, P.L.C.10
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23
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61349164855
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stereochemistry and total synthesis:
-
stereochemistry and total synthesis:. Aubry S., Lee R.E., Mahrous E.A., Small P.L.C., Beachboard D., and Kishi Y. Org. Lett. 10 (2008) 5385
-
(2008)
Org. Lett.
, vol.10
, pp. 5385
-
-
Aubry, S.1
Lee, R.E.2
Mahrous, E.A.3
Small, P.L.C.4
Beachboard, D.5
Kishi, Y.6
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24
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76949088180
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-
note
-
11a The total amount of mycolactones present in this extract was estimated to be equivalent with ∼10 injections for HPLC analysis.
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-
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25
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56749131645
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For a recent review on anion-relay-chemistry see:
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For a recent review on anion-relay-chemistry see:. Smith III A.B., and Wuest W.M. Chem. Commun. (2008) 5883
-
(2008)
Chem. Commun.
, pp. 5883
-
-
Smith III, A.B.1
Wuest, W.M.2
-
26
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0037866261
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-
For the preparation of TBS-1,3-dithiane see:
-
For the preparation of TBS-1,3-dithiane see:. Silverman R.B., Lu X., and Banik G.M. J. Org. Chem. 57 (1992) 6617
-
(1992)
J. Org. Chem.
, vol.57
, pp. 6617
-
-
Silverman, R.B.1
Lu, X.2
Banik, G.M.3
-
27
-
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0028292023
-
-
For dihydroxylation of sulfur containing substrates, see for example:
-
For dihydroxylation of sulfur containing substrates, see for example:. Walsh P.J., Ho P.T., King S.B., and Sharpless K.B. Tetrahedron Lett. 35 (1994) 5129
-
(1994)
Tetrahedron Lett.
, vol.35
, pp. 5129
-
-
Walsh, P.J.1
Ho, P.T.2
King, S.B.3
Sharpless, K.B.4
-
28
-
-
0030600166
-
-
Sammakia T., Hurley B., Sammond D.M., Smith R.S., Sobolov S.B., and Oeschger T.R. Tetrahedron Lett. 37 (1996) 4427
-
(1996)
Tetrahedron Lett.
, vol.37
, pp. 4427
-
-
Sammakia, T.1
Hurley, B.2
Sammond, D.M.3
Smith, R.S.4
Sobolov, S.B.5
Oeschger, T.R.6
-
29
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76949095234
-
-
note
-
The core alcohol 2 was synthesized by Dr. Han-Je Kim in this laboratory.
-
-
-
-
31
-
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76949096504
-
-
note
-
TBAF tested included: TBAF (Aldrich) as supplied and TBAF buffered with imidazole hydrochloride and AcOH.
-
-
-
-
33
-
-
76949097959
-
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note
-
This test was performed by Dr. Katrina L. Jackson in this laboratory. The complete data will be reported elsewhere.
-
-
-
-
34
-
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76949091010
-
-
note
-
Using the initial solvent conditions described for mycolactone E (benzene/EtOH 98.5:1.5) resulted in the overlap of several peaks, see Supplementary data.
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