SCOPUS 정보 검색 플랫폼

Volumn 396, Issue 2, 2010, Pages 817-824

Chiral HPLC analysis of venlafaxine metabolites in rat liver microsomal preparations after LPME extraction and application to an in vitro biotransformation study

(2) Da Fonseca, Patrícia a Bonato, Pierina Sueli a

a UNIVERSITY OF SÃO PAULO (Brazil)

Author keywords

Biotransformation study; Liquid phase microextraction; Microsomes; N desmethylvenlafaxine enantiomers; O desmethylvenlafaxine; Venlafaxine

Indexed keywords

1-OCTANOL; ACCEPTOR PHASE; ANALYTES; BIOTRANSFORMATION STUDY; CHIRAL HPLC; CHIRALPAK AD; CONCENTRATION RANGES; ENANTIOSELECTIVE; ENANTIOSELECTIVE ANALYSIS; IN-VITRO; LIQUID PHASE MICROEXTRACTION; MICROSOMAL PREPARATIONS; OPTIMAL CONDITIONS; ORGANIC PHASE; PH ADJUSTMENT; QUANTIFICATION LIMIT; RAT LIVERS; VALIDATED METHODS; VENLAFAXINE;

BIOCONVERSION; BIOMOLECULES; CHIRALITY; ENANTIOMERS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUIDS; LIVER; METABOLISM; METABOLITES;

SOLVENT EXTRACTION;

ANTIDEPRESSANT AGENT; CYCLOHEXANOL DERIVATIVE; VENLAFAXINE;

ANIMAL; BIOTRANSFORMATION; CHEMISTRY; CONFERENCE PAPER; EVALUATION; FRACTIONATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER MICROSOME; MALE; METABOLISM; METHODOLOGY; RAT; WISTAR RAT;

ANIMALS; ANTIDEPRESSIVE AGENTS; BIOTRANSFORMATION; CHEMICAL FRACTIONATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLOHEXANOLS; MALE; MICROSOMES, LIVER; RATS; RATS, WISTAR;

NEWCASTLE DISEASE VIRUS; RATTUS;

EID: 76849110960 PISSN: 16182642 EISSN: 16182650 Source Type: Journal
DOI: 10.1007/s00216-009-3271-1 Document Type: Conference Paper

Times cited : (30)

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