Acidic elements in histamine H3 receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 5, 2010, Pages 1581-1584

  Sander, Kerstin ^a   von Coburg, Yvonne ^a   Camelin, Jean Claude ^b   Ligneau, Xavier ^b   Rau, Oliver ^a   Schubert Zsilavecz, Manfred ^a   Schwartz, Jean Charles ^b   Stark, Holger ^a  

^a GOETHE UNIVERSITY   (Germany)

^b Bioprojet Biotech   (France)

Author keywords

Antagonists; GPCR; Histamine; Ligands; Metabolic diseases; Pharmacophore; PPAR

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ALDEHYDE DERIVATIVE; CIPROFLOXACIN; CYSTEINE DERIVATIVE; GLITAZONE DERIVATIVE; HISTAMINE H3 RECEPTOR; HISTAMINE H3 RECEPTOR ANTAGONIST; IMIDAZOLE DERIVATIVE; LIGAND; NITRILE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PIPERIDINE; PIPERIDINE DERIVATIVE; RHODANINE; THIAZOLIDINE DERIVATIVE;

ACIDITY; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CYCLIZATION; DRUG DESIGN; ELECTRONICS; NONHUMAN; PHARMACOPHORE; RODENT; STEREOSPECIFICITY; STRUCTURE ACTIVITY RELATION;

ACIDS; DRUG DESIGN; HISTAMINE ANTAGONISTS; HUMANS; LIGANDS; PPAR GAMMA; RECEPTORS, HISTAMINE H3; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 76749147279     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.01.089     Document Type: Article

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