The expression profile of FRAT1 in human gliomas

Brain Research

Volumn 1320, Issue , 2010, Pages 152-158

  Guo, Geng ^a   Mao, Xinggang ^a   Wang, Peng ^a   Liu, Bolin ^a   Zhang, Xiang ^a   Jiang, Xiaofan ^a   Zhong, Chengliang ^b   Huo, Junli ^a   Jin, Ji ^c   Zhuo, Yuzhen ^d  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c SHANXI MEDICAL UNIVERSITY   (China)

^d TIANJIN NANKAI HOSPITAL   (China)

Author keywords

catenin; FRAT1; Glioma; Immunohistochemistry; RT PCR; Western blot

Indexed keywords

BETA CATENIN; MESSENGER RNA; MOLECULAR MARKER;

ADOLESCENT; ADULT; AGED; ARTICLE; BIOLOGICAL THERAPY; BRAIN TISSUE; CANCER GRADING; CANCER GROWTH; CANCER TISSUE; CARCINOGENESIS; CHILD; CONTROLLED STUDY; FEMALE; FRAT1 ONCOGENE; GENE EXPRESSION PROFILING; GENE OVEREXPRESSION; GLIOMA; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTO ONCOGENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCHOOL CHILD; WESTERN BLOTTING; WORLD HEALTH ORGANIZATION;

ADOLESCENT; ADULT; AGED; BETA CATENIN; BLOTTING, WESTERN; BRAIN; BRAIN NEOPLASMS; CHILD; FEMALE; GLIOMA; HUMANS; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MIDDLE AGED; PROTO-ONCOGENE PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; YOUNG ADULT;

EID: 76749142862     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2010.01.037     Document Type: Article

References (38)

1. Behrens J., von Kries J.P., Kuhl M., Bruhn L., Wedlich D., Grosschedl R., and Birchmeier W. Functional interaction of beta-catenin with the transcription factor LEF-1. Nature 382 (1996) 638-642
2. Buckner J.C., Brown P.D., O'Neill B.P., Meyer F.B., Wetmore C.J., and Uhm J.H. Central nervous system tumors. Mayo Clin. Proc. 82 (2007) 1271-1286
3. Clevers H. Wnt/beta-catenin signaling in development and disease. Cell 127 (2006) 469-480
4. Dominguez I., and Green J.B. Dorsal downregulation of GSK3beta by a non-Wnt-like mechanism is an early molecular consequence of cortical rotation in early Xenopus embryos. Development 127 (2000) 861-868
5. Farr III G.H., Ferkey D.M., Yost C., Pierce S.B., Weaver C., and Kimelman D. Interaction among GSK-3, GBP, axin, and APC in Xenopus axis specification. J. Cell Biol. 148 (2000) 691-702
6. Ferkey D.M., and Kimelman D. Glycogen synthase kinase-3 beta mutagenesis identifies a common binding domain for GBP and Axin. J. Biol. Chem. 277 (2002) 16147-16152
7. Fraser E., Young N., Dajani R., Franca-Koh J., Ryves J., Williams R.S., Yeo M., Webster M.T., Richardson C., Smalley M.J., Pearl L.H., Harwood A., and Dale T.C. Identification of the Axin and Frat binding region of glycogen synthase kinase-3. J. Biol. Chem. 277 (2002) 2176-2185
8. Freemantle S.J., Portland H.B., Ewings K., Dmitrovsky F., DiPetrillo K., Spinella M.J., and Dmitrovsky E. Characterization and tissue-specific expression of human GSK-3-binding proteins FRAT1 and FRAT2. Gene 291 (2002) 17-27
9. Giles R.H., van Es J.H., and Clevers H. Caught up in a Wnt storm: Wnt signaling in cancer. Biochim. Biophys. Acta 1653 (2003) 1-24
10. Hess K.R., Broglio K.R., and Bondy M.L. Adult glioma incidence trends in the United States, 1977-2000. Cancer 101 (2004) 2293-2299
11. Ille F., and Sommer L. Wnt signaling: multiple functions in neural development. Cell. Mol. Life Sci. 62 (2005) 1100-1108
12. Jonkers J., Korswagen H.C., Acton D., Breuer M., and Berns A. Activation of a novel proto-oncogene, Frat1, contributes to progression of mouse T-cell lymphomas. EMBO J. 16 (1997) 441-450
13. Jonkers J., van Amerongen R., van der Valk M., Robanus-Maandag E., Molenaar M., Destree O., and Berns A. In vivo analysis of Frat1 deficiency suggests compensatory activity of Frat3. Mech. Dev. 88 (1999) 183-194
14. Jonkers J., Weening J.J., van der Valk M., Bobeldijk R., and Berns A. Overexpression of Frat1 in transgenic mice leads to glomerulosclerosis and nephrotic syndrome, and provides direct evidence for the involvement of Frat1 in lymphoma progression. Oncogene 18 (1999) 5982-5990
15. Kaba S.E., and Kyritsis A.P. Recognition and management of gliomas. Drugs 53 (1997) 235-244
16. Li L., Yuan H., Weaver C.D., Mao J., Farr III G.H., Sussman D.J., Jonkers J., Kimelman D., and Wu D. Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1. EMBO J. 18 (1999) 4233-4240
17. Logan C.Y., and Nusse R. The Wnt signaling pathway in development and disease. Annu. Rev. Cell Dev. Biol. 20 (2004) 781-810
18. Mao X.G., Zhang X., and Zhen H.N. Progress on potential strategies to target brain tumor stem cells. Cell. Mol. Neurobiol. 29 (2009) 141-155
19. Moon R.T., Kohn A.D., De Ferrari G.V., and Kaykas A. WNT and beta-catenin signalling: diseases and therapies. Nat. Rev. Genet. 5 (2004) 691-701
20. Pelengaris S., Khan M., and Evan G. c-MYC: more than just a matter of life and death. Nat. Rev. Cancer. 2 (2002) 764-776
21. Polakis P. Wnt signaling and cancer. Genes Dev. 14 (2000) 1837-1851
22. Remmele W., Hildebrand U., Hienz H.A., Klein P.J., Vierbuchen M., Behnken L.J., Heicke B., and Scheidt E. Comparative histological, histochemical, immunohistochemical and biochemical studies on oestrogen receptors, lectin receptors, and Barr bodies in human breast cancer. Virchows Arch. A Pathol. Anat. Histopathol. 409 (1986) 127-147
23. Saitoh T., and Katoh M. FRAT1 and FRAT2, clustered in human chromosome 10q24.1 region, are up-regulated in gastric cancer. Int. J. Oncol. 19 (2001) 311-315
24. Saitoh T., Moriwaki J., Koike J., Takagi A., Miwa T., Shiokawa K., and Katoh M. Molecular cloning and characterization of FRAT2, encoding a positive regulator of the WNT signaling pathway. Biochem. Biophys. Res. Commun. 281 (2001) 815-820
25. Saitoh T., Mine T., and Katoh M. Molecular cloning and expression of proto-oncogene FRAT1 in human cancer. Int. J. Oncol. 20 (2002) 785-789
26. Salic A., Lee E., Mayer L., and Kirschner M.W. Control of beta-catenin stability: reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts. Mol. Cell 5 (2000) 523-532
27. Sanson M., Thillet J., and Hoang-Xuan K. Molecular changes in gliomas. Curr. Opin. Oncol. 16 (2004) 607-613
28. Sareddy G.R., Panigrahi M., Challa S., Mahadevan A., and Babu P.P. Activation of Wnt/beta-catenin/Tcf signaling pathway in human astrocytomas. Neurochem. Int. 55 (2009) 307-317
29. Tolwinski N.S., and Wieschaus E. Rethinking WNT signaling. Trends Genet. 20 (2004) 177-181
30. van Amerongen R., and Berns A. Re-evaluating the role of Frat in Wnt-signal transduction. Cell Cycle. 4 (2005) 1065-1072
31. van Amerongen R., Nawijn M., Franca-Koh J., Zevenhoven J., van der Gulden H., Jonkers J., and Berns A. Frat is dispensable for canonical Wnt signaling in mammals. Genes Dev. 19 (2005) 425-430
32. van den Bent M.J., Hegi M.E., and Stupp R. Recent developments in the use of chemotherapy in brain tumours. Eur. J. Cancer 42 (2006) 582-588
33. Van der Flier L.G., Sabates-Bellver J., Oving I., Haegebarth A., De Palo M., Anti M., Van Gijn M.E., Suijkerbuijk S., Van de Wetering M., Marra G., and Clevers H. The intestinal Wnt/TCF signature. Gastroenterology 132 (2007) 628-632
34. Wang Y., Hewitt S.M., Liu S., Zhou X., Zhu H., Zhou C., Zhang G., Quan L., Bai J., and Xu N. Tissue microarray analysis of human FRAT1 expression and its correlation with the subcellular localisation of beta-catenin in ovarian tumours. Br. J. Cancer 94 (2006) 686-691
35. Wang Y., Liu S., Zhu H., Zhang W., Zhang G., Zhou X., Zhou C., Quan L., Bai J., Xue L., Lu N., and Xu N. FRAT1 overexpression leads to aberrant activation of beta-catenin/TCF pathway in esophageal squamous cell carcinoma. Int. J. Cancer 123 (2008) 561-568
36. Yost C., Farr III G.H., Pierce S.B., Ferkey D.M., Chen M.M., and Kimelman D. GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis. Cell 93 (1998) 1031-1041
37. Yu J.M., Jun E.S., Jung J.S., Suh S.Y., Han J.Y., Kim J.Y., and Kim K.W. Role of Wnt5a in the proliferation of human glioblastoma cells. Cancer Lett. 257 (2007) 172-181
38. Zhao C., Blum J., Chen A., Kwon H.Y., Jung S.H., Cook J.M., Lagoo A., and Reya T. Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo. Cancer Cell 12 (2007) 528-541