Rapid and dynamic alterations of gene expression profiles of adult porcine bone marrow-derived stem cell in response to hypoxia

Stem Cell Research

Volumn 4, Issue 2, 2010, Pages 117-128

  Wang, Suna ^a   Zhou, Yifu ^a   Seavey, Caleb N ^a   Singh, Avneesh K ^a   Xu, Xiuli ^a   Hunt, Timothy ^a   Hoyt Jr , Robert F ^a   Horvath, Keith A ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON DIOXIDE; OXYGEN; RNA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE PHASE; CELL DIFFERENTIATION; CELL HYPOXIA; CELL METABOLISM; CELL PROLIFERATION; CELL SURVIVAL; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE FUNCTION; GENOME; HEMATOPOIETIC STEM CELL; MALE; MESENCHYMAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SWINE; UPREGULATION;

ANIMALS; BONE MARROW CELLS; CELL HYPOXIA; CELLS, CULTURED; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; MESENCHYMAL STEM CELLS; MODELS, BIOLOGICAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SWINE;

ANIMALIA; SUS;

EID: 76749142384     PISSN: 18735061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.scr.2009.12.002     Document Type: Article

References (45)

1. Al-Khaldi A., Eliopoulos N., Martineau D., Lejeune L., Lachapelle K., and Galipeau J. Postnatal bone marrow stromal cells elicit a potent VEGF-dependent neoangiogenic response in vivo. Gene Ther. 10 8 (2003) 621
2. Arnhold S.J., Goletz I., Klein H., et al. Isolation and characterization of bone marrow-derived equine mesenchymal stem cells. Am. J. Vet. Res. 68 10 (2007) 1095
3. Barry F.P. Biology and clinical applications of mesenchymal stem cells. Birth Defects Res. C Embryo Today 69 3 (2003) 250
4. Beitner-Johnson D., Shull G.E., Dedman J.R., and Millhorn D.E. Regulation of gene expression by hypoxia: a molecular approach. Respir. Physiol. 110 2-3 (1997) 87
5. Belanger A.J., Lu H., Date T., et al. Hypoxia up-regulates expression of peroxisome proliferator-activated receptor gamma angiopoietin-related gene (PGAR) in cardiomyocytes: role of hypoxia inducible factor 1alpha. J. Mol. Cell. Cardiol. 34 7 (2002) 765
6. Bellot G., Garcia-Medina R., Gounon P., et al. Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains. Mol. Cell. Biol. 29 10 (2009) 2570
7. Ben-Yosef R., Paz A., Levy Y., et al. A novel device for protecting rectum during prostate cancer irradiation: in vivo data on a large mammal model. J. Urol. 181 3 (2009) 1401
8. Bobis S., Jarocha D., and Majka M. Mesenchymal stem cells: characteristics and clinical applications. Folia Histochem. Cytobiol. 44 4 (2006) 215
9. Brat D.J., Kaur B., and Van Meir E.G. Genetic modulation of hypoxia induced gene expression and angiogenesis: relevance to brain tumors. Front. Biosci. 8 (2003) d100
10. Chang M.H., Kuo W.W., Li P.C., et al. Down regulation of IGF-I and IGF-IR gene expression in right atria tissue of ventricular septal defect infants with right atria hypoxemia. Clin. Chim. Acta 379 1-2 (2007) 81
11. Das M., Dempsey E.C., Bouchey D., Reyland M.E., and Stenmark K.R. Chronic hypoxia induces exaggerated growth responses in pulmonary artery adventitial fibroblasts: potential contribution of specific protein kinase c isozymes. Am. J. Respir. Cell Mol. Biol. 22 1 (2000) 15
12. Detmar M., Brown L.F., Berse B., et al. Hypoxia regulates the expression of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) and its receptors in human skin. J. Invest. Dermatol. 108 3 (1997) 263
13. Dioum E.M., Clarke S.L., Ding K., Repa J.J., and Garcia J.A. HIF-2alpha-haploinsufficient mice have blunted retinal neovascularization due to impaired expression of a proangiogenic gene battery. Invest. Ophthalmol. Vis. Sci. 49 6 (2008) 2714
14. Early S.B., Hise K., Han J.K., Borish L., and Steinke J.W. Hypoxia stimulates inflammatory and fibrotic responses from nasal-polyp derived fibroblasts. Laryngoscope 117 3 (2007) 511
15. Eckert M.J., Perry J.T., Sohn V.Y., et al. Bioprosthetic repair of complex duodenal injury in a porcine model. J. Trauma 66 1 (2009) 103
16. Engelmann A., Speidel D., Bornkamm G.W., Deppert W., and Stocking C. Gadd45 beta is a pro-survival factor associated with stress-resistant tumors. Oncogene 27 10 (2008) 1429
17. Festy F., Hoareau L., Bes-Houtmann S., et al. Surface protein expression between human adipose tissue-derived stromal cells and mature adipocytes. Histochem. Cell Biol. 124 2 (2005) 113
18. Iop L., Chiavegato A., Callegari A., et al. Different cardiovascular potential of adult- and fetal-type mesenchymal stem cells in a rat model of heart cryoinjury. Cell Transplant. 17 6 (2008) 679
19. Jeong J.A., Hong S.H., Gang E.J., et al. Differential gene expression profiling of human umbilical cord blood-derived mesenchymal stem cells by DNA microarray. Stem Cells 23 4 (2005) 584
20. Kanichai M., Ferguson D., Prendergast P.J., and Campbell V.A. Hypoxia promotes chondrogenesis in rat mesenchymal stem cells: a role for AKT and hypoxia-inducible factor (HIF)-1alpha. J. Cell Physiol. 216 3 (2008) 708
21. Karakiulakis G., Papakonstantinou E., Aletras A.J., Tamm M., and Roth M. Cell type-specific effect of hypoxia and platelet-derived growth factor-BB on extracellular matrix turnover and its consequences for lung remodeling. J Biol. Chem. 282 2 (2007) 908
22. Kenneth N.S., and Rocha S. Regulation of gene expression by hypoxia. Biochem. J. 414 1 (2008) 19
23. Kermani A.J., Fathi F., and Mowla S.J. Characterization and genetic manipulation of human umbilical cord vein mesenchymal stem cells: potential application in cell-based gene therapy. Rejuvenation Res. 11 2 (2008) 379
24. Kietzmann T., Knabe W., and Schmidt-Kastner R. Hypoxia and hypoxia-inducible factor modulated gene expression in brain: involvement in neuroprotection and cell death. Eur. Arch. Psychiatry Clin. Neurosci. 251 4 (2001) 170
25. Kimos M.C., Wang S., Borkowski A., et al. Esophagin and proliferating cell nuclear antigen (PCNA) are biomarkers of human esophageal neoplastic progression. Int. J. Cancer 111 3 (2004) 415
26. Koritzinsky M., Magagnin M.G., van den Beucken T., et al. Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control. EMBO J. 25 5 (2006) 1114
27. Le A.D., Zhang Q., Wu Y., et al. Elevated vascular endothelial growth factor in keloids: relevance to tissue fibrosis. Cells Tissues Organs 176 1-3 (2004) 87
28. Lee B.J., Wang S.G., Roh H.J., Goh E.K., Chon K.M., and Park D.Y. Changes in expression of p53, proliferating cell nuclear antigen and bcl-2 in recurrent laryngeal cancer after radiotherapy. J. Laryngol. Otol. 120 7 (2006) 579
29. Martin-Rendon E., Hale S.J., Ryan D., et al. Transcriptional profiling of human cord blood CD133+ and cultured bone marrow mesenchymal stem cells in response to hypoxia. Stem Cells 25 4 (2007) 1003
30. Ohnishi S., Yasuda T., Kitamura S., and Nagaya N. Effect of hypoxia on gene expression of bone marrow-derived mesenchymal stem cells and mononuclear cells. Stem Cells 25 5 (2007) 1166
31. Papa S., Zazzeroni F., Bubici C., et al. Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2. Nat. Cell Biol. 6 2 (2004) 146
32. Saed G.M., Collins K.L., and Diamond M.P. Transforming growth factors beta1, beta2 and beta3 and their receptors are differentially expressed in human peritoneal fibroblasts in response to hypoxia. Am. J. Reprod. Immunol. 48 6 (2002) 387
33. Shake J.G., Gruber P.J., Baumgartner W.A., et al. Mesenchymal stem cell implantation in a swine myocardial infarct model: engraftment and functional effects. Ann. Thorac. Surg. 73 6 (2002) 1919
34. Suga H., Eto H., Inoue K., Aoi N., Kato H., Araki J., Higashino T., and Yoshimura K. Cellular and molecular features of lipoma tissue: comparison with normal adipose tissue. Br. J. Dermatol. 161 4 (2009) 819-825 Epub 2009 Apr 30
35. Sweadner K.J., and Rael E. The FXYD gene family of small ion transport regulators or channels: cDNA sequence, protein signature sequence, and expression. Genomics 68 1 (2000) 41
36. Tang Y.L. Autologous mesenchymal stem cells for post-ischemic myocardial repair. Methods Mol. Med. 112 (2005) 183
37. Tibshirani R., Hastie T., Narasimhan B., and Chu G. Diagnosis of multiple cancer types by shrunken centroids of gene expression. Proc. Natl. Acad. Sci. USA 99 10 (2002) 6567
38. Tusher V.G., Tibshirani R., and Chu G. Significance analysis of microarrays applied to the ionizing radiation response. Proc. Natl. Acad. Sci. USA 98 9 (2001) 5116
39. Wang S., Zhan M., Yin J., et al. Transcriptional profiling suggests that Barrett's metaplasia is an early intermediate stage in esophageal adenocarcinogenesis. Oncogene 25 23 (2006) 3346
40. Wu E.H., Li H.S., Zhao T., et al. Effect of hypoxia on the gene profile of human bone marrow-derived mesenchymal stem cells. Sheng Li Xue Bao 59 2 (2007) 227
41. Xu Y., Selaru F.M., Yin J., et al. Artificial neural networks and gene filtering distinguish between global gene expression profiles of Barrett's esophagus and esophageal cancer. Cancer Res. 62 12 (2002) 3493
42. Yau T.M., Kim C., Ng D., et al. Increasing transplanted cell survival with cell-based angiogenic gene therapy. Ann. Thorac. Surg. 80 5 (2005) 1779
43. Zhang H., Akman H.O., Smith E.L., Zhao J., Murphy-Ullrich J.E., and Batuman O.A. Cellular response to hypoxia involves signaling via Smad proteins. Blood 101 6 (2003) 2253
44. Zhang H., Song P., Tang Y., et al. Injection of bone marrow mesenchymal stem cells in the borderline area of infarcted myocardium: heart status and cell distribution. J. Thorac. Cardiovasc. Surg. 134 5 (2007) 1234
45. Zhou Y., Wang S., Yu Z., Hoyt Jr. R.F., Sachdev V., Vincent P., Arai A.E., Kwak M., Burkett S.S., and Horvath K.A. Direct injection of autologous mesenchymal stromal cells improves myocardial function. Biochem. Biophys. Res. Commun. 390 3 (2009) 902-907 Epub 2009 Oct 21