Nanoemulsion: A promising tool for solubility and dissolution enhancement of celecoxib

Pharmaceutical Development and Technology

Volumn 15, Issue 1, 2010, Pages 53-56

  Shakeel, Faiyaz ^a   Faisal, Mohammed S ^b  

^a AL ARAB MEDICAL UNIVERSITY   (Libyan Arab Jamahiriya)

^b HAMDARD UNIVERSITY   (India)

Author keywords

Celecoxib; Nanoemulsions; Solid dispersions; Solid lipid nanoparticles

Indexed keywords

ALCOHOL; CELECOXIB; CREMOPHOR; DIETHYLENE GLYCOL MONOETHYL ETHER; LIPID; NANOPARTICLE; POLOXAMER; POVIDONE; PROPANEDIOL DERIVATIVE; PROPYLENE GLYCOL MONOCAPRYLIC ESTER; SEFSOL 218; STEARIC ACID; TAUROCHOLIC ACID; TRIACETIN; UNCLASSIFIED DRUG; DELAYED RELEASE FORMULATION; EMULSION; NONSTEROID ANTIINFLAMMATORY AGENT; PYRAZOLE DERIVATIVE; SULFONAMIDE;

ARTICLE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG FORMULATION; DRUG SOLUBILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NANOEMULSION; PARTICLE SIZE; PRIORITY JOURNAL; SOLID; TECHNIQUE; VISCOSITY; CHEMISTRY; DELAYED RELEASE FORMULATION; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG SCREENING; DRUG STABILITY; EMULSION; PROCEDURES; SOLUBILITY;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; DRUG STABILITY; EMULSIONS; NANOPARTICLES; PYRAZOLES; SOLUBILITY; SULFONAMIDES;

EID: 76749140379     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.3109/10837450902967954     Document Type: Article

References (25)

1. Baboota S, Shakeel F, Ahuja A, Ali J, Shafiq S. Design development and evaluation of novel nanoemulsion formulation for transdermal potential of celecoxib. Acta Pharm. 2007;57:315-332.
2. Shakeel F, Baboota S, Ahuja A, Ali J, Shafiq S. Celecoxib nanoemulsion: Skin permeation mechanism and bioavailability assessment. J Drug Target. 2008;16:733-740.
3. Shakeel F, Baboota S, Ahuja A, Ali J, Shafiq S. Skin permeation mechanism and bioavailability enhancement of celecoxib from transdermally applied nanoemulsion. J Nanobiotech. 2008;6:E8.
4. Ahmed SM, Abdel-Rahman AA, Saleh SI, Ahmed MO. Comparative dissolution characteristics of bropirimine-beta-cyclodextrin inclusion complex and its solid dispersions with PEG-6000. Int J Pharm. 1993;96:5-11.
5. Popli H, Murthy RS, Miglani BD. Solid dispersions as a drug delivery system for sulfamethoxazole and nitrofurantoin. Ind J Hosp Pharm. 1994;31:97-100.
6. Shakeel F, Baboota S, Ahuja A, Ali J, Aqil M, Shafiq S. Nanoemulsions as vehicles for transdermal delivery of aceclofenac. AAPS Pharm Sci Tech. 2007;8:E104.
7. Baboota S, Alazaki A, Kohli K, Ali J, Dixit N, Shakeel F. Development and evaluation of a microemulsion formulation for transdermal delivery of terbenafine. PDA J Pharm Sci Tech. 2007;61:276-283.
8. Tanabe K, Itoh S, Iwasaki T, Nakano Y, Yamazaki M. Rectal absorption enhancement of oxaprozin using solid dispersions with polyvinylpyrrolidone. Jp J Hosp Pharm. 1994;20:509-514.
9. Kearney AS, Gabriel DL, Mehta SC, Radebaugh GW. Effect of polyvinylpyrrolidone on the crystallinity and dissolution rate of solid dispersions of the antiinflammatory CI-987. Int J Pharm. 1994;104:169-174.
10. Khidr SH. Effect of block copolymers on the dissolution of some water-insoluble drugs: Part-1 nifedipine-pluronic F-127 solid dispersions system. Bull Pharm Sci. 1994;17:81-86.
11. Baboota S, Faisal MS, Ali J, Ahuja A. Effect of poloxamer 188 on the lymphatic uptake of carvedilol loaded solid lipid nanoparticles for bioavailability enhancement. J Drug Target. 2009;17:249-256.
12. Shafiq S, Shakeel F, Talegaonkar S, Ali J, Baboota S, Ahuja A, Khar RK, Ali M. Formulation development and optimization using nanoemulsion technique: a technical note. AAPS Pharm Sci Tech. 2007;8:E 28.
13. Shafiq S, Shakeel F, Talegaonkar S, Ahmad FJ, Khar RK, Ali M. Development and bioavailability assessment of ramipril nanoemulsion formulation. Eur J Pharm Biopharm. 2007;66:227-242.
14. Shafiq S, Shakeel F, Talegaonkar S, Ahmad FJ, Khar RK, Ali M. Design and development of ramipril nanoemulsion formulation: In vitro and in vivo assessment. J Biomed Nanotech. 2007;3:28-42.
15. Shafiq S, Shakeel F. Enhanced stability of ramipril in nanoemulsion containing Cremophor-EL: A technical note. AAPS Pharm Sci Tech. 2008;9:1097-1101.
16. Ahmed M, Ramadan W, Rambhu D, Shakeel F. Potential of nanoemulsions for intravenous delivery of rifampicin. Pharmazie. 2008;63:806-811.
17. Shakeel F, Baboota S, Ahuja A, Ali J, Shafiq S. Accelerated stability testing of celecoxib nanoemulsion containing Cremophor-EL. Afr J Pharm Pharmacol. 2008;2:179-183.
18. Shakeel F, Baboota S, Ahuja A, Ali J, Faisal S, Shafiq S. Stability evaluation of celecoxib nanoemulsion containing Tween 80. Thai J Pharm Sci. 2008;32:4-9.
19. Shakeel F, Baboota S, Ahuja A, Ali J, Shafiq S. Enhanced antiinflammatory effects of celecoxib from a transdermally applied nanoemulsion. Pharmazie. 2009;64:258-259.
20. Shakeel F, Baboota S, Ahuja A, Ali J, Shafiq S. Skin permeation mechanism of aceclofenac using novel nanoemulsion formulation. Pharmazie. 2008;63:580-584.
21. Shakeel F, Baboota S, Ahuja A, Ali J, Shafiq S. Celecoxib nanoemulsion for transdermal drug delivery: Characterization and in vitro evaluation. J Disp Sci Tech. 2009;30:6 (in press). doi:10.1080/01932690802644012.
22. Sheen PC, Khetarpal VK, Cariola CM, Rowlings CE. Formulation studies of a poorly water-soluble drug in solid dispersions to improve bioavailability. Int J Pharm. 1995;118:221-227.
23. Lheritier J, Chauvet A, Abramovici B, Masse J. Improvement of the dissolution kinetics of SR 33557 by means of solid dispersions containing PEG-600. Int J Pharm. 1995;123:273-279.
24. Rahmathulla M, Gangadharappa HV, Rathod N. Solubility and dissolution improvement of rofecoxib using solid dispersion technique. Pak J Pharm Sci. 2008;21:350-355.
25. Baboota S, Shakeel F, Ahuja A, Ali J, Ahmed S, Shafiq S. Development and validation of a stability-indicating HPLC method for analysis of celecoxib in bulk drug and microemulsion formulations. Acta Chromatogr. 2007;18:116-129.