Skin permeation mechanism and bioavailability enhancement of celecoxib from transdermally applied nanoemulsion

Journal of Nanobiotechnology

Volumn 6, Issue , 2008, Pages

  Shakeel, Faiyaz ^a   Baboota, Sanjula ^b   Ahuja, Alka ^b   Ali, Javed ^b   Shafiq, Sheikh ^c  

^a Al Arab Medical Sciences University   (Libyan Arab Jamahiriya)

^b HAMDARD UNIVERSITY   (India)

^c ZYDUS RESEARCH CENTRE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

AQUEOUS PHASE; BI-LAYERS; BIOAVAILABILITY ENHANCEMENT; CELECOXIB; CYCLO-OXYGENASE-2 INHIBITOR; ENERGY MEASUREMENTS; FT-IR SPECTRUM; GASTROINTESTINAL (GI); LIPOPHILIC (LP); LONG TERM; MALE RATS; NANO EMULSION; OIL IN WATER (O/W); ORAL ADMINISTRATION; ORAL BIOAVAILABILITY; OSTEOARTHRITIS (OS); RAT SKIN; SIDE EFFECTS; SKIN PERMEATION; SPECTRAL ANALYSES; STRATUM CORNEUM (SC);

CARBOMER; CELECOXIB; CREMOPHOR; DIETHYLENE GLYCOL MONOETHYL ETHER; DRUG VEHICLE; OIL; PROPYLENE GLYCOL MONOCAPRYLIC ESTER; TRIACETIN; TRIETHANOLAMINE; WATER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AQUEOUS SOLUTION; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CAPSULE; DRUG DOSAGE FORM; DRUG DOSAGE FORM COMPARISON; DRUG MECHANISM; DRUG PENETRATION; EMULSION; HISTOPATHOLOGY; INFRARED SPECTROSCOPY; MALE; MAXIMUM PLASMA CONCENTRATION; MICROPHOTOGRAPHY; NANOEMULSION; NONHUMAN; RAT; SKIN PENETRATION; SKIN PERMEABILITY; THERMOGRAPHY; TIME TO MAXIMUM PLASMA CONCENTRATION; TITRIMETRY; TRANSDERMAL PATCH;

RATTUS;

EID: 48249122726     PISSN: None     EISSN: 14773155     Source Type: Journal    
DOI: 10.1186/1477-3155-6-8     Document Type: Article

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